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... material Fig. S2A). We could not detect significant differences in Ctnna-Citrine levels or localization in hoxb1b−/− embryos compared with sibling controls at the cell or tissue level in the neural keel (supplementary material Fig. S2A). Moreover, if Hoxb1b has an effect on cell-cell adhesion proper ...
NNF1 is an essential yeast gene required for proper spindle
NNF1 is an essential yeast gene required for proper spindle

... multiple polypeptides, making it likely that signals on both RNA and protein are required for nuclear export (Fischer et al., 1996). Recently a receptor for protein export was also identified in human cells as Rab1, and in yeast as Rip1. Both Rab1 and Rip1 interact with a specific 10 amino acid nucl ...
Cell Mediated Immunity in Virus Infections
Cell Mediated Immunity in Virus Infections

... H. Katz at Harvard, which used a very complex in vivo mouse model of T cell/B cell collaboration (23). We later read of the experiments of E. Shevach and A. Rosenthal at NIH, Bethesda, who were looking at the Ir gene question using in vitro stimulation of guinea pig T cells (24). The paradigm (25) i ...
Molecular cloning, sequence analysis, and function of the intestinal
Molecular cloning, sequence analysis, and function of the intestinal

... has emerged as a key regulator in several cellular processes, including the self-renewal of neural, hematopoietic, intestinal, and mammary stem cells (Park et al., 2003; Reinisch et al., 2006; Pietersen et al., 2008) and cancer cell proliferation. The protein functions largely, but not exclusively, ...
The FbaB-type fibronectin-binding protein of Streptococcus pyogenes
The FbaB-type fibronectin-binding protein of Streptococcus pyogenes

... of the CRIB-TagRFP at the site of M3 GAS entry (Fig. 3E). These data indicate that FbaB triggers Rac1 recruitment and activation during the process of entry. FbaB is an invasin with EC tropism Our gain-of-function analysis demonstrated the potential for FbaB to function as a potent invasin for prima ...
HODGKIN LYMPHOMA
HODGKIN LYMPHOMA

... Hodgkin lymphoma • Lost normal histologic architecture of the lymph nodes. • The only malignant cells is the classic Reed sternberg cell or one of its variants. • But the surrounding cells for the RS cells are reactive and not malignant. • Immunohistochemical staining can help in the ...
Heart regeneration
Heart regeneration

... that a more recent study has called into question the effects of periostin on cell-cycle activity or cardiac repair21.) A recent study of the mitogenic effects of NRG1 showed that simple systemic injection of this growth factor into adult mice enhanced infarct scar shrinkage and improved mechanical ...
ApexCal - Ivoclar Vivadent
ApexCal - Ivoclar Vivadent

... in contact with the calcium hydroxide paste shows three layers after about 24 hours: a thin superficial zone of cauterized and compressed tissue, a thicker zone of colliquative necrosis and a zone of varying thickness of coagulation necrosis. Vasomotor dysfunction occurs and changes take place in th ...
THE EFFECT OF CHROMIUM ON THE GROWTH OF CHLORELLA
THE EFFECT OF CHROMIUM ON THE GROWTH OF CHLORELLA

... cultivated in special 500 ml algae growing vessels, in a liquid C-30 modified culture medium, in a sterile medium at 25°C. Table 1 features the composition of the culture medium. Trace elements were added to the medium substrate from the basic solution prepared beforehand. For the inoculation, I hav ...
PartThreehemodynamic
PartThreehemodynamic

... activate renin-angiotensin-aldosterone axis  sodium and water retention by the kidneys (secondary aldosteronism) – This is not unique to CHF (e.g. can be observed in decreased osmotic pressure) ...
control of inflammation by the innate immune system
control of inflammation by the innate immune system

... through their release of cytokines and preformed mediators such as histamine, prostaglandins, and leukotrienes (38). Macrophages and DCs engulf microbes, which they detect via PRRs that are expressed on their cell surface, within endosomal/lysosomal compartments, and in the cytosol (4, 37). The net ...
soft tissue damage and healing: theory and techniques
soft tissue damage and healing: theory and techniques

... summary of steps involved in rehabilitation). The rehabilitation process of an injured athlete may be divided into stages. This is convenient, but it should be noted that the boundaries between these stages are not clearly defined. Biological systems are more than just assemblages of discrete units: ...
The alternative oxidase lowers mitochondrial reactive oxygen
The alternative oxidase lowers mitochondrial reactive oxygen

... basal ROS level that exceeds that of WT or S11 cells. Low-level DCF fluorescence was detected in control WT and S11 cells when the fluorescence signals were amplified to such an extent that AS8 images were rendered overexposed (data not shown). The addition of antimycin A to AS8 and WT cells resulte ...
Origin of muscle satellite cells in the Xenopus embryo
Origin of muscle satellite cells in the Xenopus embryo

... basement membrane surrounding the multinucleate muscle fibers. Skeletal muscle does not show continuous cell turnover in the adult organism but following muscle damage satellite cells become reactivated. They are then released from the muscle fibers, divide, start to express myogenic transcription f ...
senescent cells
senescent cells

... are compromised. Interfering with pathways that can induce senescence-associated replicative arrest are likely to promote cancer, as occurs when p16INK4a, the retinoblastoma (Rb) protein, or p53 is diminished or inactivated (67, 103). On the other hand, strategies that delay senescent cell accumulat ...
Group I discrepancy
Group I discrepancy

... Difference between A1 and A2 Reagent anti-A is a mixture of two Abs ; • Anti-A which react with both A1 and A2 cells. • Anti-A1 which reacts with A cells but not with A2 cells in simple testing . • The seeds of the plant Dolichos biflorus serve as a source of anti-A1 which is known as anti-A1 lecti ...
cathepsin-d is required for the growth of fibroblasts in - HAL
cathepsin-d is required for the growth of fibroblasts in - HAL

... D231N mutated cath-D devoid of proteolytic activity (D231N). Only cancer cells secreting wild-type or D231N pro-cath-D stimulated CD55-/-SV40 fibroblast outgrowth, whereas control cells had no effect (Figure 1B) suggesting that secreted pro-cath-D might promote 3D outgrowth of fibroblasts in a para ...
File
File

... -a watery fluid that contains everything inside the cell membrane and outside the nucleus -where chemical reactions occur -allows material to be transported quickly between the structures in the cell -store waste until they can be disposed of ...
Polyamine dependence of normal cell
Polyamine dependence of normal cell

... have shown that cell cycle progression is affected within one cell cycle after seeding cells in the presence of drugs that deplete the cellular polyamine pools [46–48]. The S phase was prolonged within the first cell cycle after seeding the cells, while effects on the G1 /S transition and the G2 +M ...
THE IMPACT OF MOLLUSCICIDES ON ENZYME ACTIVITIES IN
THE IMPACT OF MOLLUSCICIDES ON ENZYME ACTIVITIES IN

... described. The results from the enzyme histochemical studies are confined to reactions in the three cell types of the hepatopancreas: the digestive cells, the crypt cells, and the excretory cells. For the photometric measurements, the enzyme activity in the hepatopancreas will be compared with that ...
Immunocytochemistry of Rhamnogalacturonan II in Cell Walls of
Immunocytochemistry of Rhamnogalacturonan II in Cell Walls of

... Radish root cell walls (1 g) were hydrolyzed with 0.1% (w/v) Pectinase SS (Kyowa Chemical Products Co. Ltd.) in 100 ml of 20 mM Na acetate buffer (pH 4.0) for 48 h, and the pH of the digest was adjusted to 8.0 with 2 M Tris. Insoluble material was removed by centrifugation (10,000 xg, 20 min) and th ...
Megakaryoblastic Leukemia-1/2, a
Megakaryoblastic Leukemia-1/2, a

... of the tissue specificity, however, myocardin was not a candidate for regulation of skeletal muscle-specific genes or growth factor-inducible immediate early genes. We recently identified megakaryoblastic leukemia-1 (MKL1), a protein with a similarity to myocardin, as a potent transcriptional activa ...
A new multivalent B cell activation model
A new multivalent B cell activation model

... of anti-IgD. In the presence of IL-4 and IL-5, IgG1 production levels were equivalent to or better than seen when stimulation was with Hδa/1–dextran; however, IgE induction was not seen in either situation. The Ig production capacity was compared to that seen when B cells were activated with CD40L, ...
The A6B4 Integrin Can Regulate ErbB-3 Expression: Implications for
The A6B4 Integrin Can Regulate ErbB-3 Expression: Implications for

... expression diminished Akt activation. These data support the hypothesis that ErbB-3 is necessary for the ability of a6h4 to activate Akt in these cells. Of note, neither expression of a6h4 nor loss of ErbB-3 expression influenced the expression of ErbB-2 in these cells (Fig. 3A). Given that the a6h4 ...
Hypersensitivity
Hypersensitivity

... produced by the immediate release of histamine, tryptase, arachidonate and derivatives by basophils and mast cells.. ...
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Tissue engineering



Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological functions. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own right.While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.
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