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Introducing Antisense Oligonucleotides into Cells
Introducing Antisense Oligonucleotides into Cells

... fragment from the third helix has been shown to confer this property to the protein [11]. Investigators have used this peptide coupled to an antisense oligonucleotide to facilitate direct entry of the oligonucleotide into the nucleus, giving high efficiency of penetration with low dosing.  Small mo ...
A conserved role for kinesin-5 in plant mitosis
A conserved role for kinesin-5 in plant mitosis

... cytokinetic organelle, the phragmoplast (Asada et al., 1997). In the arabidopsis genome, four sequences have been annotated as kinesin-5 members, whereas in animal genomes kinesin-5 is present usually as a single-copy gene. These plant proteins have similarity to mammalian Eg5, particularly in the m ...
The Cell Membrane
The Cell Membrane

... STRUCTURE AND FUNCTION ...
Leukaemia Section T-cell/histiocyte-rich large B cell lymphoma Atlas of Genetics and Cytogenetics
Leukaemia Section T-cell/histiocyte-rich large B cell lymphoma Atlas of Genetics and Cytogenetics

... similarities with nodular lymphocyte-predominant Hodgkin's lymphoma (Pittaluga et al., 2010). These two entities may share initial transforming events that occur at germinal center B cell, followed by early divergence in the evolution of the neoplastic process (Franke et al., 2002). ...
Identification of a novel cis-acting element for fibroblast
Identification of a novel cis-acting element for fibroblast

pdf - University of California, San Francisco
pdf - University of California, San Francisco

... Cells were fixed and stained with Hoechst 33258 (blue) and antibodies to ␣-tubulin (red) and Anillin (green). (A) In control cells (no RNAi), Anillin localized to the cleavage furrow during anaphase (left panel), formed rings around the midbody matrix in telophase (center panel; note the gap in tubu ...
Plant Stem Cell Niches: Standing the Test of Time
Plant Stem Cell Niches: Standing the Test of Time

... embryonic root and part of the embryonic stem (hypocotyl). In contrast, ectopic expression of PLT1 or PLT2 results in the proliferation of basal cell identities as well as the formation of ectopic stem cell niches. Interestingly, these ectopic stem cell populations are not marked by high auxin level ...
Lecture Slides
Lecture Slides

... • Pores in the envelope allow materials to move between the nucleus and cytoplasm. • The nucleus contains a nucleolus where ribosomes are made. ...
Antivascular Actions of Microtubule
Antivascular Actions of Microtubule

... and combretastatins), can interfere with mitotic spindle formation in tumor cells, block proliferation by cell cycle arrest, and cause cell death via the induction of apoptosis, actions that undoubtedly contribute to their clinical activity (1). More recent studies have shown that most MBDs also hav ...
Gene Regulation of Carbon Fixation, Storage
Gene Regulation of Carbon Fixation, Storage

... Chlamydomonas reinhardtii (Schulze et al., 2010). Control points can be at the translational level (Mittag, 2003) or the posttranslational level (Zhang et al., 2011) and sometimes are regulated as a feedback signal system. As an example, oscillations of sugar content contributed to sugar-responsive ...
Phragmoplastin dynamics: multiple forms
Phragmoplastin dynamics: multiple forms

... and Falbel, 2002). This is based largely on observations from electron microscopy. A recent study on the formation of syncytial-type cell plates in the endosperm revealed that vesicles that are attached to the phragmoplast microtubules have a pair of kinked, rodshaped structures, resembling kinesin- ...
Deflagellation and Flagellar Regeneration in Chlamydomonas
Deflagellation and Flagellar Regeneration in Chlamydomonas

... A. Chlamydomonas In this experiment, you will be working with Chlamydomonas reinhardtii, a unicellular. Chlamydomonas is a photosynthetic organism which in the light, will grow in a defined medium containing inorganic salts and trace elements. Chlamydomonas has a cell wall and a single, large chloro ...
Nerve activates contraction
Nerve activates contraction

... new cells (cytokinesis).  The period between cell divisions is known as ‘Interphase'. Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings ...
Growth Factors
Growth Factors

... Copyright © 2009 Wolters Kluwer Health | Lippincott Williams & Wilkins ...
1st Quarter CRT Review Game
1st Quarter CRT Review Game

... temperature of 37* C and a fairly constant amount of sugar in the blood. What processes are these examples of? A. development B. Cellular organization ...
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Query Table Table Table Shared Tables Quick Start Guide

... Cells can be checked against an existing value, and the Pass/Fail status set automatically ...
Reprogramming nuclei
Reprogramming nuclei

... the transfer of nuclei into oocytes or zygotes will have a different outcome. The oocyte is a developing egg cell, and most transfer experiments in mammalian systems use secondary oocytes that have passed through the first meiotic division to split off the first polar body. The egg represents the fu ...
Plants Cells
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Introduction to Virology I Viruses Defined
Introduction to Virology I Viruses Defined

... Despite this simple three-part strategy, the tactical solutions encoded in genomes of viruses from individual families are incredibly diverse. There are countless virus particles out there with amazing diversity with respect to size, nature and toplogy of genomes, coding strategies, tissue and cell ...
CO 2
CO 2

... C4 plants  PHYSICALLY separate carbon fixation from Calvin cycle  different cells to fix carbon vs. where Calvin cycle occurs  store carbon in 4C compounds  different enzyme to capture CO2 (fix carbon)  PEP carboxylase ...
Hyndman, I. (2016) Review: the contribution of both
Hyndman, I. (2016) Review: the contribution of both

... increases. In some cell types that already show evidence of neoplasia (abnormal growth), the rate of acquisition of further mutations is increased. This increases the chance for an already-mutated cell to acquire the additional genetic alterations which are necessary for the formation of a solid tu ...
Straying off the Highway: Trafficking of Secreted
Straying off the Highway: Trafficking of Secreted

... with the wall pellet, while proteins and peptides that were not bound to the wall in vivo are lost from the extract. There are certainly other technical challenges, such as the fact that most secreted proteins are glycosylated, which complicates separation and identification, but the major confoundi ...
A Tour of the Cell
A Tour of the Cell

... • Light microscopes can be used to explore the structures and functions of cells. • When scientists examine a specimen on a microscope slide, – light passes through the specimen and – lenses enlarge, or magnify, the image. ...
Stimulating Epidermal Regeneration with Plant
Stimulating Epidermal Regeneration with Plant

... a virus to insert specific genes. The latest experimental results have shown that restoring pluripotency is also ...
Stem Cells and Types of Stem Cells
Stem Cells and Types of Stem Cells

... tissue type. For example, a blood stem cell (also called a hematopoietic stem cell) can differentiate into all cells of the blood system including the oxygen-carrying red blood cells, the white blood cells of the immune system and platelets, but not cells of the nervous system. Despite their limited ...
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Cell cycle



The cell cycle or cell-division cycle is the series of events that take place in a cell leading to its division and duplication (replication) that produces two daughter cells. In prokaryotes which lack a cell nucleus, the cell cycle occurs via a process termed binary fission. In cells with a nucleus, as in eukaryotes, the cell cycle can be divided into three periods: interphase, the mitotic (M) phase, and cytokinesis. During interphase, the cell grows, accumulating nutrients needed for mitosis, preparing it for cell division and duplicating its DNA. During the mitotic phase, the cell splits itself into two distinct daughter cells. During the final stage, cytokinesis, the new cell is completely divided. To ensure the proper division of the cell, there are control mechanisms known as cell cycle checkpoints.The cell-division cycle is a vital process by which a single-celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed. After cell division, each of the daughter cells begin the interphase of a new cycle. Although the various stages of interphase are not usually morphologically distinguishable, each phase of the cell cycle has a distinct set of specialized biochemical processes that prepare the cell for initiation of cell division.
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