Translational control of meiotic cell cycle progression
... An important outstanding question for how sequential developmental events can be ordered by translational control is how the translation initiation machinery can become targeted to and activated at specific subsets of mRNAs, and how this machinery might change in different cell types and stages. Her ...
... An important outstanding question for how sequential developmental events can be ordered by translational control is how the translation initiation machinery can become targeted to and activated at specific subsets of mRNAs, and how this machinery might change in different cell types and stages. Her ...
TORC2 Signaling is Antagonized by Protein Phosphatase
... (Inoki et al. 2005; Wullschleger et al. 2006; Zoncu et al. 2011). The TOR kinase is inhibited by the complex of rapamycin and Fpr1, a peptidyl-prolyl cis-trans isomerase. The TOR kinase is conserved in eukaryotes. Unlike fungal species, which may possess two TOR kinases, higher eukaryotes such as h ...
... (Inoki et al. 2005; Wullschleger et al. 2006; Zoncu et al. 2011). The TOR kinase is inhibited by the complex of rapamycin and Fpr1, a peptidyl-prolyl cis-trans isomerase. The TOR kinase is conserved in eukaryotes. Unlike fungal species, which may possess two TOR kinases, higher eukaryotes such as h ...
Intracellular distribution of histone mRNAs in human fibroblasts studied
... H1, H3, and H4 mRNAs. Hybridization with either 35S_ or 3H-labeled probes followed by autoradiography produced a bimodal population of cells in which =43% of cells exhibited grain densities significantly increased relative to background. Consistent with this result, the fraction of cells in S phase ...
... H1, H3, and H4 mRNAs. Hybridization with either 35S_ or 3H-labeled probes followed by autoradiography produced a bimodal population of cells in which =43% of cells exhibited grain densities significantly increased relative to background. Consistent with this result, the fraction of cells in S phase ...
Project Details - School of Biomedical Sciences
... Taurine (2-aminoethanesulphonic acid) is a semi-essential amino acid, which is not incorporated into proteins. In mammalian tissues, taurine is ubiquitous and is the most abundant free amino acid in the heart, retina, skeletal muscle, brain, and leukocytes, exhibiting multiple functions and tissue-p ...
... Taurine (2-aminoethanesulphonic acid) is a semi-essential amino acid, which is not incorporated into proteins. In mammalian tissues, taurine is ubiquitous and is the most abundant free amino acid in the heart, retina, skeletal muscle, brain, and leukocytes, exhibiting multiple functions and tissue-p ...
BioScience®
... complexity but also with the new roles emerging for cilia. These show cilia to be central players in the lives of cells, exhibiting sensory as well as motile functions and serving as sites for integrating some of the major signaling systems of the cell. These recent findings have dramatically raised ...
... complexity but also with the new roles emerging for cilia. These show cilia to be central players in the lives of cells, exhibiting sensory as well as motile functions and serving as sites for integrating some of the major signaling systems of the cell. These recent findings have dramatically raised ...
Resistance of cell membranes to different detergents - MPI
... These domains differ in their composition, physical properties, and biological functions. Membranes typically exist in a fluid state characterized by unconfined diffusion of its loosely packed lipids. This state is therefore also called the liquid-disordered (ld) phase. However, studies of liposomes ...
... These domains differ in their composition, physical properties, and biological functions. Membranes typically exist in a fluid state characterized by unconfined diffusion of its loosely packed lipids. This state is therefore also called the liquid-disordered (ld) phase. However, studies of liposomes ...
Unicellular vs. Multicellular
... Unicellular organisms vary in size. The smallest organism a bacteria is only 300 nanometers and range upto 20cm. These organisms usually posses cilia, flagella or pseudopidia that help them in locomotion. They have simple body with basic features. Reproduction is both by asexual and sexual means. Nu ...
... Unicellular organisms vary in size. The smallest organism a bacteria is only 300 nanometers and range upto 20cm. These organisms usually posses cilia, flagella or pseudopidia that help them in locomotion. They have simple body with basic features. Reproduction is both by asexual and sexual means. Nu ...
Antiproliferative and apoptotic effects of O
... In addition, we found that TRX induced accumulation of cells in the G1 and G2 phases of the cell cycle whereas DFO arrested cells in G1 and during progression through S phase. These data suggest that the partial inhibition of DNA replication observed after exposure to DFO may be due to a lower effic ...
... In addition, we found that TRX induced accumulation of cells in the G1 and G2 phases of the cell cycle whereas DFO arrested cells in G1 and during progression through S phase. These data suggest that the partial inhibition of DNA replication observed after exposure to DFO may be due to a lower effic ...
The Functions Of Polarized Water And Membrane Lipids: A Rebuttal
... existence of lipid bilayers in cellular membrane to be compelling" is not difficult to understand. One can hardly expect journal editors to accept "major" reviews ot lipid membranes from those who do not subscribe to the conventional view of lipid membranes. T o be fair and scientific, the critical ...
... existence of lipid bilayers in cellular membrane to be compelling" is not difficult to understand. One can hardly expect journal editors to accept "major" reviews ot lipid membranes from those who do not subscribe to the conventional view of lipid membranes. T o be fair and scientific, the critical ...
Research Interests
... morphogenesis. Repeated pair-wise changes in these morphogenic characters (from cellular processes to patterning elements) that are phylogenetically correlated will suggest hypotheses of functional relationships between the correlated characters that can then be tested. Likewise, variations in a mo ...
... morphogenesis. Repeated pair-wise changes in these morphogenic characters (from cellular processes to patterning elements) that are phylogenetically correlated will suggest hypotheses of functional relationships between the correlated characters that can then be tested. Likewise, variations in a mo ...
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... (Holmgren 1984). Drosophila segments form simultaneously from a syncytial blastoderm in a process that differs dramatically from vertebrate somitogenesis. However, the Drosophila condition is evolutionarily derived within the arthropods (Peel 2004). Thus, the initial discovery that genes related to ...
... (Holmgren 1984). Drosophila segments form simultaneously from a syncytial blastoderm in a process that differs dramatically from vertebrate somitogenesis. However, the Drosophila condition is evolutionarily derived within the arthropods (Peel 2004). Thus, the initial discovery that genes related to ...
Mitochondria in Lymphocytes of Normal and
... impossible to obtain accurate estimations of mitochondrial content, partly because of the physical difficulties involved in counting these bodies and partly because of the fact that some of the mitochondria occasionally fail to take the dye, while some fading of the stain occurs." Although Wiseman's ...
... impossible to obtain accurate estimations of mitochondrial content, partly because of the physical difficulties involved in counting these bodies and partly because of the fact that some of the mitochondria occasionally fail to take the dye, while some fading of the stain occurs." Although Wiseman's ...
Chaotic expression dynamics implies pluripotency: when theory and
... domain, referred to as an "attractor" in dynamical systems theory (as discussed by Kauffman and others [11,12]). The attractor can be a fixed point if the cellular state does not change over time, but it can be a closed cycle when the cellular state oscillates. Depending on the initial conditions, c ...
... domain, referred to as an "attractor" in dynamical systems theory (as discussed by Kauffman and others [11,12]). The attractor can be a fixed point if the cellular state does not change over time, but it can be a closed cycle when the cellular state oscillates. Depending on the initial conditions, c ...
coccolith
... bottom of the marine food chain, excellent food for herbivorous bacteria. Some have flagella (whip-like appendages) so unlike plants, are capable ...
... bottom of the marine food chain, excellent food for herbivorous bacteria. Some have flagella (whip-like appendages) so unlike plants, are capable ...
The Control of Patterning and Morphogenesis during Root
... species, there are only two cell types in the root epidermis: cells that produce long hairlike extensions (i.e., root hair cells, which are derived from trichoblasts) and cells that do not &e., hairless cells, which are derived from atrichoblasts; Cormack, 1949, 1962; Cutter, 1978). The arrangement ...
... species, there are only two cell types in the root epidermis: cells that produce long hairlike extensions (i.e., root hair cells, which are derived from trichoblasts) and cells that do not &e., hairless cells, which are derived from atrichoblasts; Cormack, 1949, 1962; Cutter, 1978). The arrangement ...
Plk4/SAK/ZYG-1 in the regulation of centriole
... Active Plk4/SAK kinase is present at duplicating mother centrioles during G1/S and the protein levels increase at both centrioles into mitosis [29]. In addition to centriole localization, Plk4/SAK protein levels are regulated and, when aberrant, centriole assembly is either amplified or decreased co ...
... Active Plk4/SAK kinase is present at duplicating mother centrioles during G1/S and the protein levels increase at both centrioles into mitosis [29]. In addition to centriole localization, Plk4/SAK protein levels are regulated and, when aberrant, centriole assembly is either amplified or decreased co ...
Expression of a Nondegradable Cyclin B1 Affects
... these misshaped cells are grossly disorganized, focused around the nucleus, whereas they were entirely missing or abnormally organized along the cell cortex. A high percentage of cells expressing nondestructible cyclin B1 had doubled DNA content as a result of undergoing endomitosis. During anaphase ...
... these misshaped cells are grossly disorganized, focused around the nucleus, whereas they were entirely missing or abnormally organized along the cell cortex. A high percentage of cells expressing nondestructible cyclin B1 had doubled DNA content as a result of undergoing endomitosis. During anaphase ...
Correlated Discharge among Cell Pairs within the Oculomotor
... and c) were obtained during fixation behavior for two sets of triplets. The correlations among triplets were visualized in a manner similar to the visualization of correlations among pairs (Perkel et al., 1975). Although the time interval between spikes Figure 3. Cross-correlations of position cells ...
... and c) were obtained during fixation behavior for two sets of triplets. The correlations among triplets were visualized in a manner similar to the visualization of correlations among pairs (Perkel et al., 1975). Although the time interval between spikes Figure 3. Cross-correlations of position cells ...
Expression of a Nondegradable Cyclin B1 Affects
... these misshaped cells are grossly disorganized, focused around the nucleus, whereas they were entirely missing or abnormally organized along the cell cortex. A high percentage of cells expressing nondestructible cyclin B1 had doubled DNA content as a result of undergoing endomitosis. During anaphase ...
... these misshaped cells are grossly disorganized, focused around the nucleus, whereas they were entirely missing or abnormally organized along the cell cortex. A high percentage of cells expressing nondestructible cyclin B1 had doubled DNA content as a result of undergoing endomitosis. During anaphase ...
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... microinjection into the yolk cell. The most effective approach was found to be microinjection of 35S directly into the yolk at 3 hpf, and allowing label incorporation into the biosynthetic pathway for GAG chain sulfation for 5 hours (Fig. 2B). Thus, after morpholino injection at the 1- to 2-cell sta ...
... microinjection into the yolk cell. The most effective approach was found to be microinjection of 35S directly into the yolk at 3 hpf, and allowing label incorporation into the biosynthetic pathway for GAG chain sulfation for 5 hours (Fig. 2B). Thus, after morpholino injection at the 1- to 2-cell sta ...