Responses to Water Deficit
... thereby triggering a signal transduction pathway(s) that induces gene expression. Therefore, several different stresses may trigger the s,ameor similar signal transduction pathways. The induction pathway(s) is also poorly understood, although there is evidence that there is more than one pathway. Th ...
... thereby triggering a signal transduction pathway(s) that induces gene expression. Therefore, several different stresses may trigger the s,ameor similar signal transduction pathways. The induction pathway(s) is also poorly understood, although there is evidence that there is more than one pathway. Th ...
CELL SCAVENGER HUNT
... The mitochondria are organelles that specialize in making energy for the cell. It is often referred to as the “powerhouse of the cell”. The mitochondria take food particles and convert the food energy into ATP. ATP is a form of energy that cells can ultimately use. The cafeteria dining area is like ...
... The mitochondria are organelles that specialize in making energy for the cell. It is often referred to as the “powerhouse of the cell”. The mitochondria take food particles and convert the food energy into ATP. ATP is a form of energy that cells can ultimately use. The cafeteria dining area is like ...
The Production and Action of Interferon in Chinese Hamster Cells
... amounts being produced in 'aged' ceils. Its apparent tool. wt. was 25 ooo. C H O - K t cells, an established line of Chinese hamster cells, did not synthesize interferon in response to viruses, but were sensitive to its action. A functioning interferon system has been discovered in all classes of ve ...
... amounts being produced in 'aged' ceils. Its apparent tool. wt. was 25 ooo. C H O - K t cells, an established line of Chinese hamster cells, did not synthesize interferon in response to viruses, but were sensitive to its action. A functioning interferon system has been discovered in all classes of ve ...
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... It is not yet clear whether these sequence features are found in the RBD itself or whether they comprise a distinct domain. The latter case would support Han’s two-component model for recruitment of mRNAs to condensed phases. However, the former suggests a bifunctional model, in which LCSs bind mRN ...
... It is not yet clear whether these sequence features are found in the RBD itself or whether they comprise a distinct domain. The latter case would support Han’s two-component model for recruitment of mRNAs to condensed phases. However, the former suggests a bifunctional model, in which LCSs bind mRN ...
Getting RNA and Protein in Phase
... It is not yet clear whether these sequence features are found in the RBD itself or whether they comprise a distinct domain. The latter case would support Han’s two-component model for recruitment of mRNAs to condensed phases. However, the former suggests a bifunctional model, in which LCSs bind mRN ...
... It is not yet clear whether these sequence features are found in the RBD itself or whether they comprise a distinct domain. The latter case would support Han’s two-component model for recruitment of mRNAs to condensed phases. However, the former suggests a bifunctional model, in which LCSs bind mRN ...
Raman spectroscopy of a single living cell
... (Apoptosis) through our Raman Spectroscopy as we can trap two cells in our dual beam Optical Tweezers and bring them near to each other to see how they interact and what molecular interactions lead to the ultimate end. ...
... (Apoptosis) through our Raman Spectroscopy as we can trap two cells in our dual beam Optical Tweezers and bring them near to each other to see how they interact and what molecular interactions lead to the ultimate end. ...
Discovery of a novel ligand that modulates the
... through a reptin–AGR2 peptide interaction assay of the top 30 hits from the in silico screen (see Fig. S1 and S2†) and Liddean, the most active analog obtained through chemical optimization (see Scheme S1 and Fig. S4 and S5†). (b) The Autodock prediction of the binding mode of 1 is shown as black st ...
... through a reptin–AGR2 peptide interaction assay of the top 30 hits from the in silico screen (see Fig. S1 and S2†) and Liddean, the most active analog obtained through chemical optimization (see Scheme S1 and Fig. S4 and S5†). (b) The Autodock prediction of the binding mode of 1 is shown as black st ...
Syllabus, BIOSC 2105: Cell Signaling Spring Term, 2014 Instructor
... 5. How does CaMKII slow intracellular [Ca] decline? ...
... 5. How does CaMKII slow intracellular [Ca] decline? ...
... and "TATA" box-like structures [29, 30]. The 5'-flanking regions of CC chemokines contains a number of potential binding sites for several nuclear factors, such as NF-κB and NF-IL-6/C/EBPβ [29, 30]. In addition, the regulated on activation normal T-cell expressed and secreted (RANTES) promotor conta ...
free medium for progeny cell division - Journal of Cell Science
... initiated, their descendants had reached different stages in the daughter generation. The right side of Fig. 4B shows the relationship between cell age of the daughter cells at insertion of the continuous 36-h starvation and their intermitotic time (= cell age at the next mitosis). It was found that ...
... initiated, their descendants had reached different stages in the daughter generation. The right side of Fig. 4B shows the relationship between cell age of the daughter cells at insertion of the continuous 36-h starvation and their intermitotic time (= cell age at the next mitosis). It was found that ...
AP Biology Syllabus
... a hypothesis, collection, analysis, and presentation of data, and a clear discussion of results. To ensure the lab component of the course is met, on average, two out of every four days is devoted to laboratory work. Students are required to come in to the laboratory prepared and ready to complete t ...
... a hypothesis, collection, analysis, and presentation of data, and a clear discussion of results. To ensure the lab component of the course is met, on average, two out of every four days is devoted to laboratory work. Students are required to come in to the laboratory prepared and ready to complete t ...
The regulation of carbohydrate metabolism in animal cells: Isolation
... grow in glucose-free medium supplemented with maltose, trehalose or starch; however, in the present report we show that such growth is due to the activity of serum enzymes which convert these substrates to glucose. Cells, cell-culture media and methods, and other procedures are as previously describ ...
... grow in glucose-free medium supplemented with maltose, trehalose or starch; however, in the present report we show that such growth is due to the activity of serum enzymes which convert these substrates to glucose. Cells, cell-culture media and methods, and other procedures are as previously describ ...
Adhesion molecules in cancer invasion and metastasis
... One class of cell-cell adhesion molecules implicated in tissue formation is the Ca ++ -dependent, developmentally regulated transmembrane cadherin proteins16. Cadherins are the most interesting among all adhesion molecules since when they are present all adhesion interactions may be continued even i ...
... One class of cell-cell adhesion molecules implicated in tissue formation is the Ca ++ -dependent, developmentally regulated transmembrane cadherin proteins16. Cadherins are the most interesting among all adhesion molecules since when they are present all adhesion interactions may be continued even i ...
Identification of a Platelet-aggregating Factor of
... thrombin (data not shown). Furthermore, this platelet aggre gation was not induced by ADP-efflux from the tumor cells, since the platelet aggregation was always measured in PRPcontaining apyrase (0.5 units/ml), an ADP degrading enzyme. These data indicate that the platelet aggregation induced by NL- ...
... thrombin (data not shown). Furthermore, this platelet aggre gation was not induced by ADP-efflux from the tumor cells, since the platelet aggregation was always measured in PRPcontaining apyrase (0.5 units/ml), an ADP degrading enzyme. These data indicate that the platelet aggregation induced by NL- ...
Isolation and Sequencing of Actin1, Actin2 and Tubulin1 Genes
... Actin and tubulin are highly abundant conserved proteins in eukaryotic cells, which participate in more protein-protein interactions than any other proteins [4,5]. These properties, together with the actin capacity to carry out the transition between monomeric (G-actin) and filamentous (F-actin) sta ...
... Actin and tubulin are highly abundant conserved proteins in eukaryotic cells, which participate in more protein-protein interactions than any other proteins [4,5]. These properties, together with the actin capacity to carry out the transition between monomeric (G-actin) and filamentous (F-actin) sta ...
Systems Microbiology ..(Download PowerPoint)
... before been able to conduct comprehensive studies of microbes and their interactions with one another in their natural habitats. Now, a new study provides the first inventories of microbial capabilities in nine very different types of ecosystems, ranging from coral reefs to deep mines. Science News ...
... before been able to conduct comprehensive studies of microbes and their interactions with one another in their natural habitats. Now, a new study provides the first inventories of microbial capabilities in nine very different types of ecosystems, ranging from coral reefs to deep mines. Science News ...
Cell Membranes and Disease
... (cyclic AMP), a product of this enzyme, leads to most of the known actions of these hormones in the liver.20 A second major insight into the molecular basis of cellular responses resulted from the demonstration that the plasma membrane of the target cells contains both the recognition system and eff ...
... (cyclic AMP), a product of this enzyme, leads to most of the known actions of these hormones in the liver.20 A second major insight into the molecular basis of cellular responses resulted from the demonstration that the plasma membrane of the target cells contains both the recognition system and eff ...
The Dock and Lock Method: A Novel
... The idea, approach, and proof-of-concept of the dock and lock (DNL) method, which has the potential for making a large number of bioactive molecules with multivalency and multifunctionality, are reviewed. The key to the DNL method seems to be the judicious application of a pair of distinct protein d ...
... The idea, approach, and proof-of-concept of the dock and lock (DNL) method, which has the potential for making a large number of bioactive molecules with multivalency and multifunctionality, are reviewed. The key to the DNL method seems to be the judicious application of a pair of distinct protein d ...
Chapters 4 and 5 Cell Structures, Functions and Transport
... STRUCTURE • This is the boundary between the cell cytoplasm & the environment • Is partially permeable • Made up 45% protein & 45% phospholipids with the remaining 10% cholesterol, glycoprotein & glyolipids ...
... STRUCTURE • This is the boundary between the cell cytoplasm & the environment • Is partially permeable • Made up 45% protein & 45% phospholipids with the remaining 10% cholesterol, glycoprotein & glyolipids ...
The Mouse T Cell Receptor: Structural Heterogeneity of Molecules
... glycosylated (Allison et al., 1982) it is likely that to a considerable degree the heterogeneity observed in the one- and two-dimensional electrophoretic analyses results from posttranslational modification rather than from variability in amino acid sequence. The virtual identity of the V8 protease ...
... glycosylated (Allison et al., 1982) it is likely that to a considerable degree the heterogeneity observed in the one- and two-dimensional electrophoretic analyses results from posttranslational modification rather than from variability in amino acid sequence. The virtual identity of the V8 protease ...
Most fundamental cellular processes are not
... the number of structural interfaces of a protein rather than its number of partners. It also suggested different models for network evolution through gene duplication, depending on whether or not a newly created protein connects to a pre-existing structural interface. Finally, we showed that protein ...
... the number of structural interfaces of a protein rather than its number of partners. It also suggested different models for network evolution through gene duplication, depending on whether or not a newly created protein connects to a pre-existing structural interface. Finally, we showed that protein ...
OMB No. 0925-0046 (Approved Through 5/31/2016)
... We have elucidated cell intrinsic and microenvironmental pathways which regulate BCSCs including BRCA1, Notch, Hedgehog (HH), Wnt, as well as the cytokines IL-6 and IL-8. a. We demonstrated that the hereditary breast cancer gene BRCA1 plays a key role in the regulation of human mammary stem/progenit ...
... We have elucidated cell intrinsic and microenvironmental pathways which regulate BCSCs including BRCA1, Notch, Hedgehog (HH), Wnt, as well as the cytokines IL-6 and IL-8. a. We demonstrated that the hereditary breast cancer gene BRCA1 plays a key role in the regulation of human mammary stem/progenit ...
Fluorescent tagging of an endogenous gene by
... Detection of TurboGFP integration into the target locus: Various methods can be used to assess integration of exogenous DNA into a target locus. The methods of detection that we tested were high-content imaging, flow cytometry, PCR, and Sanger sequencing. Below we describe the detection of TurboGFP ...
... Detection of TurboGFP integration into the target locus: Various methods can be used to assess integration of exogenous DNA into a target locus. The methods of detection that we tested were high-content imaging, flow cytometry, PCR, and Sanger sequencing. Below we describe the detection of TurboGFP ...
Protein for Pets is Happy to Announce The
... store holds a dog walk every Saturday to bring people and their dogs together with other like-minded, health conscious P4P customers. The Santa Monica store, as well as the other P4P stores, will periodically team up with rescues and shelters across California and hold adoption days at the store. Ma ...
... store holds a dog walk every Saturday to bring people and their dogs together with other like-minded, health conscious P4P customers. The Santa Monica store, as well as the other P4P stores, will periodically team up with rescues and shelters across California and hold adoption days at the store. Ma ...
From skin to the treatment of diseases the possibilities of iPS cell
... were also capable of forming adult chimeras and generate functional germ cells. This finding shows that fully reprogrammed iPSCs can be generated by the transduction of somatic cells with four transcription factors. In further investigations, a wide range of murine cells was tested for their reprogr ...
... were also capable of forming adult chimeras and generate functional germ cells. This finding shows that fully reprogrammed iPSCs can be generated by the transduction of somatic cells with four transcription factors. In further investigations, a wide range of murine cells was tested for their reprogr ...