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Ribosomes as Antibiotic Targets Ribosomes as
Ribosomes as Antibiotic Targets Ribosomes as

... Shigella (causes intestinal illness) grew from 32% to 67%! ...
Conservation of inner nuclear membrane targeting sequences in
Conservation of inner nuclear membrane targeting sequences in

... In postmitotic cells and cells undergoing a closed mitosis, inner nuclear membrane (INM)–localized integral membrane proteins also have to find their way through the NPC. Upon synthesis, polytopic membrane proteins are first incorporated into the endoplasmic re­ ticulum (ER) membrane and travel via ...
Fungi
Fungi

... Protozoa are unicellular eukaryotic microorganisms that lack cell walls . They are generally colorless and motile. Protozoa are distinguished from prokaryotes by their eukaryotic nature and usually greater size, from algae by their lack of chlorophyll, from yeasts and other fungi by their motility a ...
07_Lecture_Presentation
07_Lecture_Presentation

... globular proteins • Later studies found problems with this model, particularly the placement of membrane proteins, which have hydrophilic and hydrophobic regions • In 1972, S. J. Singer and G. Nicolson proposed that the membrane is a mosaic of proteins dispersed within the bilayer, with only the hyd ...
Autophagy and Immunity
Autophagy and Immunity

... degrades the cytoplasmic contents. Large: 400-1500 nm May originate from ER or from fusion of lipid-containing vesicles that form ‘sequestration crescent’. ...
RESPIRATION AND PROTEIN SYNTHESIS IN ESCHERICHIA COLI
RESPIRATION AND PROTEIN SYNTHESIS IN ESCHERICHIA COLI

... ` . clean" membrane or wall preparations . Because rather delicate but metabolically important associations may exist in the cell between the plasma membrane and various cytoplasmic components such as DNA, RNA, ribosomes, nucleic acid synthetases, etc ., we have attempted to isolate membrane-envelop ...
Protein Secretion in Plants: from the trans
Protein Secretion in Plants: from the trans

... seems likely that protein secretion has undergone specific modifications in the plant lineage. A few examples from plant development may illustrate requirements that have to be met by the protein secretory system. Vegetative pollen cells secrete a peptide ligand (SCR) into their cell wall that interac ...
CELL
CELL

Spatial control of phospholipid flux restricts endoplasmic reticulum
Spatial control of phospholipid flux restricts endoplasmic reticulum

... 2003). After fertilization, the maternal and paternal pronuclei form, increase in size, and migrate toward each other, meeting in the middle as the embryo enters mitosis (Fig. 1C). The nuclear envelopes become permeable, and microtubules penetrate to interact with the chromosomes. The nuclear envelo ...
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The Effects of Nocodazole on Amoeba Pseudopod Counts
The Effects of Nocodazole on Amoeba Pseudopod Counts

... leukemia cells, as well as other cancerous cells. This study however, focused on the effects of nocodazole on the pseudopodia count of amoebae. Amoebae are members of the protozoa family and are classified into two different species amoeba dubia and amoeba proteus. They are large unicellular organis ...
Different subcellular locations of secretome components of
Different subcellular locations of secretome components of

Polyamine dependence of normal cell
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... when bound to cyclins that are expressed cyclically during the cell cycle. Polyamine biosynthesis varies bicyclically during the cell cycle with peaks in enzyme activities at the G1 /S and S/G2 transitions. The enzyme activities are regulated at transcriptional, translational and post-translational ...
7-3 Cell Boundaries
7-3 Cell Boundaries

... used to describe the concentrations: Hypertonic– surrounding solution is MORE concentrated than interior of cell – water moves out of the cell. • hypotonic - surrounding solution is LESS concentrated than interior of cell – water moves into of the cell • isotonic - surrounding solution is EQUALLY co ...
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A role for the DNA-damage checkpoint kinase Chk1 in the virulence

... Sgarlata and Perez-Martin, 2005a). To determine the kinase activity associated with Cdk1 during b-factor-dependent filament formation, we took advantage of the Schizosaccharomyces pombe protein Suc1, which is known to bind specifically to mitotic CDKs with high affinity (Ducommun and Beach, 1990) an ...
08A-MembraneStructure
08A-MembraneStructure

... • They may be covalently bonded either to lipids, forming glycolipids, or, more commonly, to proteins, forming glycoproteins. • The oligosaccharides on the external side of the plasma membrane vary from species to species, individual to individual, and even from cell type to cell type within the sam ...
08A-MembraneStructure
08A-MembraneStructure

... • They may be covalently bonded either to lipids, forming glycolipids, or, more commonly, to proteins, forming glycoproteins. • The oligosaccharides on the external side of the plasma membrane vary from species to species, individual to individual, and even from cell type to cell type within the sam ...
Endothelial Cell Changes as an Indicator for Upcoming Allograft
Endothelial Cell Changes as an Indicator for Upcoming Allograft

... scale from 1 to 5: (1) quiet endothelial cell layer with a regular cell morphology and distribution, without any sign of cellular activation; (2) slightly irregular endothelial cell morphology and/or distribution, but without any sign of cellular activation; (3) mild to moderate irregular endothelia ...
AN 700 EXAM 2 KEY TERMINOLOGY
AN 700 EXAM 2 KEY TERMINOLOGY

... dense (dense = more EC fibers, fewer cells); contains larger blood vessels than those in lamina propria Smooth muscle layer; contains inner (closer to submucosa; circular but longitudinal in transverse cut) and outer (longitudinal but circular in transverse cut) ME layers Consists of upper underlyin ...
Honors Biology Name: Microorganisms Quiz Review A) BACTERIA
Honors Biology Name: Microorganisms Quiz Review A) BACTERIA

... 2. Are there any other organisms on this planet classified as prokaryotes? 3. What is the proper name for bacteria that have the following shapes? a. Round b. Rod-like c. Spirals ...
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A Novel Role of Annexin A2 in Human Type I Collagen Gene
A Novel Role of Annexin A2 in Human Type I Collagen Gene

Sectional Anatomy of the Brain - Dr. Leichnetz
Sectional Anatomy of the Brain - Dr. Leichnetz

... Corpus callosum- rostrum, genu, and rostral body of corpus callosum interconnect frontal lobes Septum pellucidum- vertical membranous partition separating lateral ventricles Anterior limb, internal capsule- separates the caudate from the putamen Caudate nucleus- in lateral wall of lateral ventricle; ...
Using Gene Expression Noise to Understand Gene Regulation
Using Gene Expression Noise to Understand Gene Regulation

... by which regulators modulate this process. In many of these studies, the analysis of regulatory behavior required the application of an external input or a change in environmental conditions. It is not always easy to introduce such a perturbation, but what if they already existed in nature? As discu ...
Molecular Biology of the Cell
Molecular Biology of the Cell

... IBIOS, Bioinformatics and Genomics Option ...
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Cell nucleus



In cell biology, the nucleus (pl. nuclei; from Latin nucleus or nuculeus, meaning kernel) is a membrane-enclosed organelle found in eukaryotic cells. Eukaryotes usually have a single nucleus, but a few cell types have no nuclei, and a few others have many.Cell nuclei contain most of the cell's genetic material, organized as multiple long linear DNA molecules in complex with a large variety of proteins, such as histones, to form chromosomes. The genes within these chromosomes are the cell's nuclear genome. The function of the nucleus is to maintain the integrity of these genes and to control the activities of the cell by regulating gene expression—the nucleus is, therefore, the control center of the cell. The main structures making up the nucleus are the nuclear envelope, a double membrane that encloses the entire organelle and isolates its contents from the cellular cytoplasm, and the nucleoskeleton (which includes nuclear lamina), a network within the nucleus that adds mechanical support, much like the cytoskeleton, which supports the cell as a whole.Because the nuclear membrane is impermeable to large molecules, nuclear pores are required that regulate nuclear transport of molecules across the envelope. The pores cross both nuclear membranes, providing a channel through which larger molecules must be actively transported by carrier proteins while allowing free movement of small molecules and ions. Movement of large molecules such as proteins and RNA through the pores is required for both gene expression and the maintenance of chromosomes. The interior of the nucleus does not contain any membrane-bound sub compartments, its contents are not uniform, and a number of sub-nuclear bodies exist, made up of unique proteins, RNA molecules, and particular parts of the chromosomes. The best-known of these is the nucleolus, which is mainly involved in the assembly of ribosomes. After being produced in the nucleolus, ribosomes are exported to the cytoplasm where they translate mRNA.
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