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a zebrafish model of myotubular myopathy
a zebrafish model of myotubular myopathy

... disorders of childhood. It is caused by mutations in the myotubularin (MTM1) gene. In vitro, MTM1 functions as a lipid phosphatase that dephosphorylates specific phosphoinositides (PIs). Via its ability to modify PIs, MTM1 serves as a critical regulator of several processes, most notably endocytosis ...
Cell Structure
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... • The eukaryotic cell has many different organelles that each have their own function that contributes the work of the whole cell. • The fact that all these organelles have evolved and can work together for the good of the whole cell gives eukaryotic cells the ability to do a lot more than prokaryot ...
Biology H Chapters 4, 5
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... • Currently trying to map all human genes to the appropriate chromosome. • Example: gene responsible for sickle cell anemia is located on chromosome 11. ...
BP 201T. HUMAN ANATOMY AND PHYSIOLOGY-II
BP 201T. HUMAN ANATOMY AND PHYSIOLOGY-II

... Scope: This subject is designed to impart fundamental knowledge on the structure and functions of the various systems of the human body. It also helps in understanding both homeostatic mechanisms. The subject provides the basic knowledge required to understand the various disciplines of pharmacy. Ob ...
All women with fair hair have blue eyes
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... The majority of drivers consistently break the current speed limit - and without penalty, as the police are unable to enforce the speed limit in all cases. There is no evidence to suggest that driving at 80 mph is more dangerous than driving at 70 mph. If the speed limit were raised, the police coul ...
Biology Principles Review
Biology Principles Review

... - cells >>>> tissues >>>> organs >>>> organ systems >>>> organism - each cell performs a specific function for each tissue or organ - as cells mature, they shape and contents change - as cells become specialized they may contain organelles that are NOT common to all cells (for example: plastids, cel ...
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Cell Structure and Function
Cell Structure and Function

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The following terms must be included on your concept map

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Functional role of c-Jun/PP2B in regulation of gene expression

... Lung cancer with its high prevalence, recurrent rate and metastatic potential becomes the leading cause of cancer death in Taiwan. Malignant pleural effusion (MPE) is a poor prognostic sign for patients with non-small cell lung cancer (NSCLC). The generation of MPE is largely regulated by vascular e ...
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... When a cell reaches its size limit, it will either stop growing or it will divide. Cell division keeps cells from getting too large. It is also the way that cells reproduce. A cell’s cycle of growing and dividing is called the cell cycle. The cell cycle has three main stages.. During interphase, the ...
Cell Structure and Function
Cell Structure and Function

... The cytoplasmic/plasma/cell membrane  Contains glycolipids as well as complex lipids called sterols  Cholesterol molecules found in animal cell membranes not found in prokaryotic membranes(except for some mycoplasmas  Sterols make the membrane less permeable to most biological molecules  Help to ...
Homeostatic Crisis at Cellular Level
Homeostatic Crisis at Cellular Level

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Cell Structure PPT - Madison County Schools

... synthesize the steroid sex hormones. – Enzymes synthesize lipids • (oils, phospholipids, & steroids) ...
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... may result in only partial absorption and, thus, lower bioavailability. For example, the oral route requires that a drug dissolves in the GI fluid and then penetrates the epithelial cells of the intestinal mucosa, yet disease states or the presence of food may affect this process. ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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