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Prokaryotic Cell Structure and Function
Prokaryotic Cell Structure and Function

... the bacteria and offer metabolic and physiological flexibility of the organism’s response to environmental changes and stresses. With rare exceptions, plasmids exist within the cell as highly supercoiled circular dsDNA molecules of a few kilobases, such as ColVK30 which is 2 kbp in length, to over a ...
Physiology 3 Transport PDQ
Physiology 3 Transport PDQ

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Nguyen-ICAAC-IDSA-2008-A-972

... SCV as compared to NP. Cytosolic antibiotics (OXA, MXF), show higher potency (lower EC50) against NP than against SCV. These differences may be rationalized by the apparent different subcellular localization of both strains, antibiotics proving more effective or potent in the compartment where they ...
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The University of Kansas Center for Research on Learning
The University of Kansas Center for Research on Learning

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Anaemia - NHSBT Hospitals and Science

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The CDC Biofilm Reactor

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blood pressure - Cloudfront.net

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KS4 Blood Vessels

... Capillaries: role and position These vessels link arteries with veins. They are found all over the body and are essential for the exchange of materials between the blood and other body cells. artery ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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