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Blood: Its Components and Its Role
Blood: Its Components and Its Role

... Red blood cells, or erythrocytes, are responsible for carrying oxygen from the lungs throughout the circulatory system. The oxygen is carried by a protein part of the blood known as hemoglobin. Red blood cells have flexible membranes that allow them to squeeze through the very smallest blood vessel. ...
Westmead Hospital
Westmead Hospital

... Please Note – this document is a guide only, and your Nephrologist/Renal Clinic may have a different preferred format ...
Autophagy and Immunity
Autophagy and Immunity

... membrane-enclosed vesicles Taken up by phagocytes, preventing release of intracellular components ...
Ultrastructure of the Infectious and Reproductive
Ultrastructure of the Infectious and Reproductive

... The most remarkable feature of the IF is its huge amount of periplasmic material. Although a number of proteins are located in the periplasm (Gortz et al., 1988; and unpublished), the nature and significance of the periplasmic material are largely unknown. During the infection process the IF always ...
Mitochondrial involvement in tracheary element
Mitochondrial involvement in tracheary element

... factor 1 (Apaf1), and causes recruitment of procaspase-9 which transactivates due to close proximity.7 Clearly, cytochrome c, Apaf1, and procaspase 9 do not define the entire apparatus, since other apoptosis inducing factors (e.g. AIF, diablo) play key roles in the mitochondrial pathway.8,9 There ar ...
PDF
PDF

... discussed the advantages of the zebrafish model for the study of embryonic myogenesis. Zebrafish embryos are optically clear, which allows for easy lineage-tracking in live embryos. By using confocal imaging and informatics systems, researchers can follow the cellular trajectories of one to hundreds ...
Word
Word

... established a quantitative integration assay for primary cells to assess the role of ...
Invasion: Breaching Anatomical Barriers
Invasion: Breaching Anatomical Barriers

... Avoiding the Host Defenses 1. Hiding within host cells • Cell-to-cell Spreading Shigella and Listeria species ...
Role of bilateral zones of ingressing superficial cells
Role of bilateral zones of ingressing superficial cells

... (Fig. 9). These may be superficial cells in the process of leaving the surface. More laterally, cells with many protrusions appear to be contacting, and possibly migrating over, each other and the blastocoel wall. The extent to which the deep layer contributes to mesodermal structures cannot be quan ...
Biotic and abiotic elicitors induce biosynthesis and accumulation of
Biotic and abiotic elicitors induce biosynthesis and accumulation of

... evaporation and used for further analysis. Calibration and determination of trans-resveratrol concentration using the HPLC analysis The resveratrol compound used for further HPLC analysis was dissolved in methanol at a concentration of 1 mgl-1 and stored away from direct light at 4 0C until used. Th ...
Respiratory system
Respiratory system

... are what makes the blood red and it also delivers oxygen to body cells and takes carbon dioxide back to the lungs. They make over half the volume of blood. The second blood cell is the white blood cell. They fight off viruses and germs and helps clean the blood. It is the biggest cell in your blood. ...
Cellular Polarity in Prokaryotic Organisms
Cellular Polarity in Prokaryotic Organisms

... for the actin polymerization that drives bacterial motility in the host cell cytoplasm. IcsA belongs to a large family of auto-transporters that, along with other members of this family, is found localized at the old cell pole (Jain et al. 2006). In fact, even in artificially generated, spherical E. ...
Integument
Integument

... most common type. Cells of the stratum germinativum may proliferate and invade the dermis and hypodermis. Slow growing and tends not to metastasize. Full cure in 99% of the cases. (b) Squamous cell carcinoma - Develops in the stratum spinosum. Grows rapidly and could metastasize to nearby lymph node ...
for? of Immune Homeostasis: Molecules to Die FOXO Transcription
for? of Immune Homeostasis: Molecules to Die FOXO Transcription

... researchers several years ago, it was work by the groups of Burgering and Greenberg (9, 10) that initially demonstrated this in mammalian systems. Subsequently FOXOs have been found to be phosphorylated in vivo on multiple threonine (T1, T2) and serine residues (S1, S2, S3, S4, S5) (Fig. 2). Three o ...
Chapter 1
Chapter 1

... – Atoms, small units of matter that participate in chemical reactions, and molecules, two or more atoms joined together. ...
T-tubule proliferation facilitates trans
T-tubule proliferation facilitates trans

... electrophysiology were examined by stand- ...
Alterations of the EGFR and Hippo/ Yes
Alterations of the EGFR and Hippo/ Yes

... In part 1, we have investigated the connection between ERK1/2 and Hippo/YAP pathway in NSCLC. Herein, we show that ERK1 and ERK2 have an effect on the Hippo/YAP pathway in human NSCLC cells. Firstly, inhibition of ERK1/2 by siRNA or small-molecular inhibitors decreased the YAP protein level, the rep ...
A Computational and Experimental Study
A Computational and Experimental Study

... the underlying pore morphology, but also by the relatively flexible zinc–oxygen cores which permit utilization of the void volume of the channel to accommodate stresses.[21] In summary, this work represents the first study that has combined experimental and computational approaches to establish the ...
open cell regime - Colorado State University
open cell regime - Colorado State University

... • Ship plumes ingested into open cells result in deeper and brighter clouds with higher liquid water amounts and rain rates. Heavier rainfall in the nearby clouds presumably leads to enhanced moisture convergence below the ship track. ...
Beta cell restoration
Beta cell restoration

... Our short and mid-term focus is on establishing proof in human clinical studies that one or more of the repurposed drug candidates will indeed enhance beta cell survival in humans and that it can be safely tolerated by patients (proof of concept). Another key area is identifying biomarkers, or indic ...
Microfabrication in Biology and Medicine
Microfabrication in Biology and Medicine

... systems (micro TAS), have existed for .30 years, with several applications attaining commercial and/or scientific success. Although there have been a few applications to biology or medicine during that time, only in the past decade has a closer union emerged. Several factors have driven this recent ...
Sponges are sessile, feed by phagocytosis, and reproduce sexually
Sponges are sessile, feed by phagocytosis, and reproduce sexually

... water passes through the ostia and out through theosculum. Bacteria smaller than 0.5 microns in size are trapped by choanocytes, which are the principal cells engaged in nutrition, and are ingested by phagocytosis. Particles that are larger than the ostia may be phagocytized by pinacocytes. In some  ...
4.25.05 Excretion and Cardiovascular
4.25.05 Excretion and Cardiovascular

... • Blood pressure due to the pumping of the heart accounts for the flow of blood in the arteries. • Systolic pressure is high when the heart expels the blood. • Diastolic pressure occurs when the heart ventricles are relaxing. • This pressure is so strong, it can be measured through your skin using t ...
Westchester Community College
Westchester Community College

... Discuss the role that B-lymphocytes and plasma cells play in an antibodymediated response; Discuss the role that the various T-lymphocytes play in a cell-mediated response; Describe the structure of an antibody; List the five antibody types and their specific roles in immunity; Discuss primary versu ...
What is cellular Senescence? - Roswell Park Cancer Institute
What is cellular Senescence? - Roswell Park Cancer Institute

... After this interval the senescence growth arrest becomes essentially permanent, effectively suppressing the ability of the stressed cell to form a malignant tumor. One early manifestation of the senescent phenotype is the expression of cell surface–bound IL-1α. This cytokine acts in a juxtacrine man ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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