• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Skeletal muscle contraction
Skeletal muscle contraction

... surrounded by a white connective tissue called perimysium. Each fasciculus, in turn, is made up of bundles of muscle cells (also called muscle fibers). Within each cell there are cylindrical bundles of myofibrils. These myofibrils are composed of two types of myofilaments, which are the actual contr ...
III - UO Blogs
III - UO Blogs

... •  gametangia are not under the control of the het genes ...
Modelling a Debris Flow with PCRaster
Modelling a Debris Flow with PCRaster

Probing the invasiveness of prostate cancer cells in a 3D
Probing the invasiveness of prostate cancer cells in a 3D

... Cancer cell motility has already been systematically visualized and analyzed in microchannels and on two-dimensional substrates (10). However, the speed and character of cell motility is quite different from that normally seen in three-dimensional in vivo studies (11). Microfabricated three-dimensio ...
Dictyostelium cytokinesis: from molecules to mechanics
Dictyostelium cytokinesis: from molecules to mechanics

... on the biochemical basis for this mechanical process considering both the contractile apparatus and the viscoelastic cortex that provides the context for contractility. We will concentrate on research utilizing the cellular slime mold Dictyostelium discoideum, a system that has provided numerous ins ...
The Polymeric Immunoglobulin Receptor Accumulates in
The Polymeric Immunoglobulin Receptor Accumulates in

... PCI2 cells stably transfected with plgR were differentiated in the presence of NGF on matrigel-coated chamber slides as described above. For some experiments, cells stably expressing pIgR were transiently transfected with eDNA encoding the human LDL-R before differentiation. Control experiments were ...
Finite element analysis of the pressure
Finite element analysis of the pressure

... cells are known to endure strain levels between 100 and 150 % as they deform to pass through narrow channels (Cha et al. 2012), or when deformed using techniques such as controlled cavitation rheology (Li et al. 2013) and optical tweezers (Dao et al. 2003). However, the microstructure of red blood c ...
In Vitro Toxicology and Cellular Fate Determination Using
In Vitro Toxicology and Cellular Fate Determination Using

... cultures, the Biomek® 2000 workstation dispensed the CellTiter-Glo™ Reagent and then agitated the plates for two minutes on the integrated shaker. Plates were incubated for 10 minutes in the dark at room temperature before being read on an EG&G MicroLumat Luminometer. Apo-ONE™ Assays of staurosporin ...
Storage of Quinolizidine Alkaloids in Epidermal Tissues
Storage of Quinolizidine Alkaloids in Epidermal Tissues

... What are the biochemical characteristics of epider­ mal cells? From the cytological point of view they are highly specialized in that they produce a protective cuticle, which shows distinct biotoxic properties [36]. Epidermal cells with the exception of the guard cells have no chloroplasts and are t ...
the pathogenesis of sendai virus infection in the mouse lung twe
the pathogenesis of sendai virus infection in the mouse lung twe

... within 24 hr of infection and had reached its peak by the 5th day. Since the cells of the bronchial mucous membrane were showing degenerative changes from the 1st day, it is reasonable to assume that the virus was replicating in these cells and that it was the replication of the virus that was respo ...
Hijacking of eukaryotic functions by intracellular bacterial pathogens
Hijacking of eukaryotic functions by intracellular bacterial pathogens

... niche. Researchers interested in the biology of these pathogens have often addressed two basic phenomena: the mode of entry and the intracellular lifestyle of the pathogen within the infected cell. Bacterial uptake has been intensively analyzed in non-phagocytic cells, also known as “non-professiona ...
Workbook 2 - Blood and Circulation
Workbook 2 - Blood and Circulation

... What is blood and why is it important? By the end of this topic you should: (a) Understand the need for and the structure of the human circulatory system and know that there are two separate circulations, one to the lungs and one to the other organs of the body. (b) Be able to draw and label diagram ...
Wnt3a-mediated chemorepulsion controls movement
Wnt3a-mediated chemorepulsion controls movement

... images. The last panel shows the location of GFP cells in the bilateral heart fields, indicated by white outline (for the corresponding movie, see Movie 1 in the supplementary material). (C) vMHC in situ hybridisation of an HH11 embryo after live imaging shows normal heart morphogenesis and cardiac ...
Role of plectin in cytoskeleton organization and dynamics
Role of plectin in cytoskeleton organization and dynamics

... antibodies, for instance due to the expression of differentially spliced transcripts, or contain the protein in a form in which the epitopes of the antibodies tested were inaccessible. The widespread expression of plectin has been confirmed by RNase protection assays using cDNA representative of a v ...
Signal Requirements for the Generation of CD4+ and CD8+ T
Signal Requirements for the Generation of CD4+ and CD8+ T

... early stages of rejection, with perivascular mononuclear cell infiltrates and interendothelial cell gaps rapidly progressing to blood vessel lining disruption.5 The immunohistological demonstration of EC involvement in allogeneic as well as self-directed immune response has prompted a number of in v ...
Why do muscles shorten? 112ch11
Why do muscles shorten? 112ch11

... Cardiac cells depolarize for long periods and do not have the quick twitches that are characteristic of skeletal muscle Cardiac cells are linked by Gap Junctions so when Na+ enters a cell it can cross into and depolarize the next cell and so-on. While each skeletal myofiber requires a depolarization ...
Blood Vessels: The Vascular System
Blood Vessels: The Vascular System

...  Intercostal arteries supply the muscles of the thorax wall  Other branches of the thoracic aorta supply the ...
From yeast to patient neurons and back again - Lindquist Lab
From yeast to patient neurons and back again - Lindquist Lab

... Rationale Behind Yeast-to-Human a-syn Platforms The two original questions driving the two research papers in question were conceived independently. In Tardiff et al.,1 we asked two questions: Can we identify small molecules from unbiased chemical screens that correct multiple toxic phenotypes assoc ...
Document
Document

... makes it capable of giving blood to all groups. While blood group (AB) is a universal recipient because it has both antigen a and antigen b and doesn't contain any antibodies, which makes it capable of receiving blood from all types. 4-Because it deals with the arrangement of living organisms accor ...
The Care and Feeding of the Microscope Lab 5
The Care and Feeding of the Microscope Lab 5

... Microscopists improve contrast by coloring specimens with stains (dyes) that bind to cellular structures and absorb light to provide contrast. ...
-Chain Cytokine Signals γ Activation Is Independent of Jak3
-Chain Cytokine Signals γ Activation Is Independent of Jak3

... expansion in vivo. When adoptively transferred, IL-2-deficient or IL-2R-deficient DO11.10 T cells challenged with OVA peptide underwent comparable expansion compared with wild-type T cells (14, 15). Similarly, after correcting the autoimmune defect in IL2R␤-deficient mice by selective expression of ...
Invertebrates
Invertebrates

... Arthropods and mollusks for example have an open circulatory system. In this type of system, there is neither a true heart or capillaries as are found in humans. Instead of a heart there are blood vessels that act as pumps to force the blood along. The closed circulatory system of a few mollusks and ...
Grade 5 Biology Title Page
Grade 5 Biology Title Page

... likely to die of lung cancer. But long before that, you’ll find your lung capacity decreased. You may develop asthma and, if that doesn’t stop you, emphysema – where 90 per cent of all cases are caused by smoking. ...
Cell Cycle Regulation of the Activity and Subcellular Localization of
Cell Cycle Regulation of the Activity and Subcellular Localization of

... monoclonal antibodies, Plkl was found to be diffusely distributed throughout interphase cells; in dividing cells, however, a striking association with postmitotic bridges was noted, suggesting that Plkl might be discarded at the end of mitosis through shedding of the midbody into the culture medium ...
PDF file - Via Medica Journals
PDF file - Via Medica Journals

... patients, whereas the density of G cells and gastrin levels were elevated [12, 13]. These data suggest an intricate balance among immune factors and stomach neuropeptides, including somatostatin and gastrin, in the control of gastrointestinal function. Alterations in relative numbers of G and D cell ...
< 1 ... 396 397 398 399 400 401 402 403 404 ... 1638 >

Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report