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LC1
LC1

... Animal and plant cells have different contents Cell differentiation is needed in all organisms Cell specialisation happens in humans Microscopes have helped us better understand cells The nucleus is crucial in the cell Chromosomes control who you are Cells need to replicate accurately Stem cells sho ...
Immunocytochemical Localization of the
Immunocytochemical Localization of the

... In order to obtain reliable and reproducible immunocytochemical results, cells must be fixed to cross-link the proteins and cellular elements in situ and to allow access to the immunocytochemical re agents. However, results may vary' depending upon the tissue prepara tion and type of fixative used a ...
Dehydroascorbate Uptake Activity Correlates with
Dehydroascorbate Uptake Activity Correlates with

... Downloaded from on June 16, 2017 - Published by www.plantphysiol.org Copyright © 2003 American Society of Plant Biologists. All rights reserved. ...
- Mochtar Riady Institute
- Mochtar Riady Institute

... can induce apoptosis or impair monocyte-derived dendritic cell (MDDC) function. However, it is still unclear which AFP domain (D-AFP) plays major role in this function. Results: As expected monocytes cultured in the presence of Granulocyte MacrophageColony Stimulating Factor (GM-CSF) and Interleukin ...
Healing the Heart
Healing the Heart

... Although standard tests can detect atherosclerosis, they aren’t foolproof. They may reveal plaques, but give no indication whether or not they are life-threatening. Tests like angiography, for example, where doctors inject a dye into the bloodstream and track it with xrays, can show how much blood i ...
All About Blood - Spark Innovations
All About Blood - Spark Innovations

... Remember when we talked about white blood cells and how they find germs. The white blood cells are always on the lookout for invaders trying to take over your body. What’s amazing is that a single drop of blood can contain anywhere from (ask students if they remember how many per drop) 7,000 to 25,0 ...
Study Guide Answers: Blood and the Cardiovascular System
Study Guide Answers: Blood and the Cardiovascular System

... Changes in the structure or function of the valves; Fluid or swelling in the sac around the heart; Inflammation of the heart (myocarditis)  Past or current heart attack  Poor blood supply to the heart arteries  Abnormal heart rhythms (arrhythmias) A change in pressure in the blood within the heart c ...
OMB No. 0925-0046 (Approved Through 5/31/2016)
OMB No. 0925-0046 (Approved Through 5/31/2016)

... citations) c. Currently, HER2+ breast cancers are classified based on HER2 gene amplification, a distinction which is utilized to guide HER2 targeted therapeutics. However, retrospective clinical analysis had suggested significant clinical benefit for adjuvant trastuzumab, even in the absence of HER ...
Measuring the mechanics of biofilms at multiple lengthscales
Measuring the mechanics of biofilms at multiple lengthscales

... Methods for measuring the mechanics of surface-attached bacterial systems on a range of lengthscales enables enhanced understanding of their disease-causing properties. Biofilms are multicellular communities of sessile, interacting microbes that form infections readily on medical devices and in chro ...
this PDF file
this PDF file

... 5. Choyke L, Hayes S. From Archives the of the AFIP Primary extragonadal Germcell tumours of the retroperitoneum: differentiation of primary and secondary tumours. Radiographics. 1993; 13: 1365–75. 6. Pectasides D, Aravantinos G, Visvikis A, et al. Platinumbased chemotherapy of primary extragonadal ...
An Increase in B cell and Cytotoxic NK cell
An Increase in B cell and Cytotoxic NK cell

... well as functional T cell responses to recall antigens and mitogens, were assessed by flow cytometry in 40 patients with relapsing multiple sclerosis before and after one-year natalizumab treatment. Results: Absolute numbers of all major lymphocyte populations increased after treatment, most markedl ...
Virus Specific Cytological Effects in Infected Plant Cells
Virus Specific Cytological Effects in Infected Plant Cells

... to certain tissues like the phloem. Various distinct regular or irregular patterns of chlorotic or necrotic tissues develop on leaves indicating that the distribution of systemically spread virus is not really uniform throughout the plant. The effects of systemically spread virus are obviously regul ...
transcription factor foxc2 demarcates the jugular lymphangiogenic
transcription factor foxc2 demarcates the jugular lymphangiogenic

... from specific segments of the deep venous system (11). In the anterior part of the embryo, lymphatics are derived from the jugular lymph sacs, which, in turn, are derived from the jugular segment of the cardinal veins (11-14). Endothelial cells (ECs) in the jugular segment of the cardinal veins are ...
Biotransformation of xenobiotics
Biotransformation of xenobiotics

... The most important oxidative reactions : hydroxylation, epoxide formation, dealkyation and deamination Reductive reactions : reduction of carbonyl-, azo- or nitro compounds, dehalogenation Methylation and Desulfuration Reactions of biotransformation can lead to more toxic substances than the parent ...
Chemical Suppression of Defects in Mitotic Spindle Assembly
Chemical Suppression of Defects in Mitotic Spindle Assembly

... Our work was inspired by the observation that the DNA replication inhibitor hydroxyurea (HU) can rescue a mutant carrying a temperaturesensitive allele (ipl1-321) of the Aurora B kinase, whose inactivation leads to defective chromosome segregation and genome instability (Figure 2) (Lampson and Chees ...
Autophagy in Stem Cell Maintenance and Differentiation
Autophagy in Stem Cell Maintenance and Differentiation

... luripotent stem cells are defined by their self-renewal capacity and their ability to develop into cells of all 3 germ layers. Theoretically, those cells hold great promise for regenerative medicine, where they could be used to replace damaged cells of a tissue, thus constituting a powerful tool to ...
unit 2 nutrition ii
unit 2 nutrition ii

... 18. Solve this crossword. Across 1. A liquid that appears when it is hot or when we practice physical exercise 3. They carry blood towards the heart 5. They are two spongy and pink organs 8. The air comes out 9. It is a muscular organ that pumps blood throughout the body 11. They are located in the ...
The Development of Novel Approaches to the Identification of
The Development of Novel Approaches to the Identification of

... Activation Test (h-CLAT) by using the THP-1 cell line, where two independent laboratories have performed analyses with 9 chemicals (33), and one laboratory has conducted tests with 29 chemicals (34). One potentially fruitful initiative is an activity supported by ECVAM and COLIPA (the European Cosme ...
Hepatitis C virus can accumulate mutations that confer resistance to
Hepatitis C virus can accumulate mutations that confer resistance to

... • Serves as a source for cell-cell spread; In vivo relevance ...
Chapter 2: Human Anatomy
Chapter 2: Human Anatomy

... Protect against disease Help regulate body temperature Prevent serious blood loss after injury ...
Chapter 23 Circulation and Respiration
Chapter 23 Circulation and Respiration

... enlarge, this is the pulse. Most arteries that we are able to feel a pulse on must cross over a bone for us to identify the pulse readily (wrist and carotid arteries are the most often used to take one’s pulse). Capillaries Capillaries are the smallest blood vessels in the human body as well as othe ...
Mineral Nutrition in Plants II
Mineral Nutrition in Plants II

... the young stems and leaves place themselves so that the leaves may be well illuminated...they are extremely heliotropic; and this probably serves...as a guide (for) the buried seeds through fissures in the ground or through overlying masses of vegetation, into the light and air. - Charles Darwin “Th ...
Respiratory System PPT File
Respiratory System PPT File

... • Irritation of the trachea and larynx • Reduced lung function and breathlessness due to swelling and narrowing of the lung airways and excess mucus in the lung passages • Impairment of the lungs’ clearance system, leading to the build-up of poisonous substances, which results in lung irritation and ...
1.2 Unifying Themes of Biology
1.2 Unifying Themes of Biology

... • A system is an organized group of interacting parts. – A cell is a system of chemicals and processes. – A body system includes organs that interact. – An ecosystem includes living and nonliving things that interact. ...
Memories M. Carrie Miceli May 17, 2002
Memories M. Carrie Miceli May 17, 2002

...  "of the many aged people still living on the Faroes who had measles in 1781, not one was attacked a second time"  "all the old people who had not gone through with measles in earlier life were attacked when they were exposed to infection” Ludwig Panum (Danish Physician)  Immune memory is long li ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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