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PMT Poster
PMT Poster

... Transporters (PMT) group will extend the multidisciplinary research project focused on membrane transporters that are major determinants of the absorption, distribution and elimination of many clinically used drugs. • The two major superfamilies under study are the SoLute Carrier Superfamily (SLC) a ...
pLV-RNAi - Biosettia
pLV-RNAi - Biosettia

Resistance of cell membranes to different detergents - MPI
Resistance of cell membranes to different detergents - MPI

... lipids. Such diversity would be unnecessary if lipid bilayers served only as hydrophobic barriers and homogeneous twodimensional solvents for membrane proteins. As is now increasingly appreciated, membranes show extensive lipid-driven compartmentalization, giving rise to distinct membrane domains. T ...
Required Early Complement Activation in Contact
Required Early Complement Activation in Contact

... to participate in induction of acquired B cell humoral immunity. In this study, we present evidence that C also participates in acquired T cell immunity. We found that C was involved in early events of the efferent elicitation phase of contact sensitivity (CS), and delayed-type hypersensitivity (DTH ...
lecture 16
lecture 16

... – circulatory fluid is called blood – is confined at all times to a series of vessels – blood is distinct from interstitial fluid – exchange takes place between the blood in the vessels and the interstitial fluid in the tissues – in capillary beds in many animals – closed system does have a heart (o ...
An Overview on Respiratory System
An Overview on Respiratory System

... forms two layers: one adheres to the lung and other to the wall of the thoracic cavity. The pleural cavity is only a potential space. The thin film of serous fluid separates the two layers of the pleura, which allow them glide over each other, preventing friction between them during breathing. The e ...
Squamous cell carcinoma: an atypical presentation
Squamous cell carcinoma: an atypical presentation

... These types of lesions are more frequent in males and tend to have a higher incidence in older people. The leading risk factor is ultraviolet exposure (sunlight). Other factors associated with this pathology are the presence of congenital genome repair anomaly, such as xeroderma pigmentosum, human p ...
Lecture 2 “Influence of pharmaceutical factors, such as physical
Lecture 2 “Influence of pharmaceutical factors, such as physical

... •As a quality control measure to check performance during the shelf life •To predict performance under various dosing conditions („biorelevant“ methods) •To verify that the quality of a product is not adversely affected when there is a change in excipients or manufacturing method (can sometimes be u ...
7-3 Movement Through The Membranes
7-3 Movement Through The Membranes

... in a given volume of solvent. Mass/Volume e.g. ...
Slide 1
Slide 1

... subunits of glucose, with (α1 → 6) -linked branches, but glycogen is more extensively branched (on average, every 8 to 12 residues) and more compact than starch • In hepatocytes glycogen is found in large granules, which are themselves clusters of smaller granules composed of single, highly branched ...
CUSTOMER_CODE SMUDE DIVISION_CODE SMUDE
CUSTOMER_CODE SMUDE DIVISION_CODE SMUDE

... constitute over 90% of the tissue in some areas of the brain. They are many branched and have a somewhat star like shape. c. ...
KOBITO1 Encodes a Novel Plasma Membrane Protein Necessary
KOBITO1 Encodes a Novel Plasma Membrane Protein Necessary

... cytokinesis defects (Zuo et al., 2000), suggesting that KOR is involved in cellulose synthesis during cell division, cell elongation, and secondary cell wall formation. By contrast, genetic evidence shows that CESA isoforms are specialized in terms of function. Indeed, strong mutant alleles of rsw1 ...
Hierarchical Models of the Visual System - Serre Lab
Hierarchical Models of the Visual System - Serre Lab

... architectures have been developed in computer vision (LeCun et al., 1998). These neural networks do not mimic the organization of the visual cortex in detail, but biology is often cited as a source of inspiration. While these models are not, strictly speaking, models of the visual system, their impr ...
File - Illinois Online High School
File - Illinois Online High School

... that scan or photo to this document. Keep photos/images small. B. NEXT, Type or copy & paste typed responses that you have prepared, in the spaces provided on THIS DOCUMENT. Only add your responses in the boxes that ask for them – such as “Add Responses Here”. Some assignments may require you to upl ...
reviews - Lab. Biodados UFMG
reviews - Lab. Biodados UFMG

... re-enter a quiescent state and can undergo enforced differentiation32–34. Deletion of Rb in the skin results in a decrease in the number of label-retaining, slowly cycling cells in the stem cell compartment35. These data raise two different possibilities: first, RB-mutant skin stem cells might die o ...
medical device development and testing
medical device development and testing

... Medical Device Development and Testing Southwest Research Institute® (SwRI®) offers expertise in diverse areas such as biomaterials and tissue engineering, materials characterization, biological encapsulation, and medical device development. Scientists in the Materials and Bioengineering Section hav ...
Programmed Changes in Form during Moss Development
Programmed Changes in Form during Moss Development

... This inhibition could be reversed by adding calcium or by washing out the lanthanum and adding cytokinin. However, it is not clear whether initial cell formation and/or bud assembly was inhibited. Clear support for a requirement for calcium in initial cell formation came from experiments in which th ...
Cell membrane phospholipids
Cell membrane phospholipids

... • DPPC is the major lipid component of lung surfactant (extracellular fluid layer lining the alveoli) Surfactant reduces the pressure needed to reinflate alveoli So, it prevents alveolar collapse (atelectasis) ...
REVIEWS TBP-associated factors (TAF s): multiple, selective
REVIEWS TBP-associated factors (TAF s): multiple, selective

... are sequence-specific DNA-binding proteins whose recognition sites are present within the vicinity of their target promoters. A typical activator contains a promoter-targeting region, which comprises generally a sequence-specific DNA-binding domain and a separate activation region (reviewed in Ref. ...
European Respiratory Society Annual Congress 2013
European Respiratory Society Annual Congress 2013

... (Wingless/integrase-1) signaling pathway has been implicated in various proliferative diseases, including lung cancer. In addition, the phosphorylation of GSK-3β, a key regulator of the WNT pathway, correlates with ASM hypertrophy. The WNT pathway may therefore be of particular significance in under ...
BCL_Paper3_GermsAndTheImmuneSystem
BCL_Paper3_GermsAndTheImmuneSystem

... The reproduction system of protozoa is strange in that it can be either asexual or sexual. The asexual reproduction process is the same as the binary fission process described for bacteria. The sexual reproduction process, however, is much more complicated. First, protozoa form gametes which are th ...
A theoretical model based upon mast cells and histamine to explain
A theoretical model based upon mast cells and histamine to explain

... flare responses (74). These effects are inhibited by pyrilamine, indicating that the response to VIP is mediated by histamine, and furthermore, MCs can release VIP by histamine liberators (24). Direct effects of EMFs on mast cells As mentioned before, epidermal MCs may release inflammatory mediators ...
Canine Musculoskeletal Support - Veterinary Center of Parker Inc.
Canine Musculoskeletal Support - Veterinary Center of Parker Inc.

... Black currant juice – an excellent source of anthocyanins with antioxidant properties. Carrot – source of whole vitamin A complex, trace minerals Bovine liver – provides important cell substrates for hepatic cells and Kupffer cells. This is important for metabolic processes of the liver and for toxi ...
Clear Cell Tumors of the Head and Neck: An
Clear Cell Tumors of the Head and Neck: An

... The clear cell variant of chondrosarcoma (CCC) is an extremely rare variant that accounts for about 2% of all chondrosarcoma. Only nine cases are reported in the head and neck area. The histological finding of head and neck cases are consistent with general features of this entity in the whole body ...
The ongoing search for the molecular basis of plant osmosensing
The ongoing search for the molecular basis of plant osmosensing

... stomata; how well they accomplish this task contributes to their water use efficiency, a key factor in drought response (Long and Ort, 2010). At the cellular level, water is critical for maintaining and controlling an important driving force in plant cells called turgor pressure. Much of a plant cel ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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