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Selective Gene Delivery to Head and Neck Cancer Cells via an
Selective Gene Delivery to Head and Neck Cancer Cells via an

... vectors has been noted to occur based on a deficiency of either or both of these cellular receptor classes (17, 18, 40). On this basis, we evaluated the relative levels of both receptor classes in the resistance of SCCHN cell lines as compared with levels in the highly permissive HeLa cell line. Dir ...
Slide 1
Slide 1

... The heart is one of the most important organs the entire human body because it pumps blood through it. The heart is a muscular organ that is found in all vertebrates. http://www.mayoclinic.com/health/heart-disease-prevention/WO00041 ...
Human embryonic stem cells express a unique set
Human embryonic stem cells express a unique set

... The first human ES (hES) cell line was established only recently (Thomson et al., 1998), and 12 lines are publicly available worldwide (NIH Human Embryonic Stem Cell Registry). Despite their great potential, hES cells have not been a prolific source of information. This is mainly due to the technica ...
1. Most organisms are active within a limited
1. Most organisms are active within a limited

... pH is a measure of the concentration of hydrogen ions per litre of solution ...
Introduction to Dermatology
Introduction to Dermatology

... Skin is the largest organ in human body Dermatological diseases can cause social and psychological problems, also it may affect ability to work (e.g. Chronic hand dermatitis.) Skin is the gate of the body(might reflect systemic disease). ...
Planctomyces stranskae - International Journal of Systematic and
Planctomyces stranskae - International Journal of Systematic and

... One form (morphotype Va) possesses an apical spike and thin pili on the globose hemisphere. The other form (morphotype Vb) lacks the spike, but its globose hemisphere is covered by numerous rigid, multifibrillar, and tapered appendages, thicker and more substantial than pili; we call them bristles. ...
Identification of a Platelet-aggregating Factor of
Identification of a Platelet-aggregating Factor of

... peared to be in the order NL-4 > NL-17, NL-44 > NL-14. Among three clones with high platelet-aggregating activity, NL-17 was highly metastatic, while NL-4 and NL-44 were rarely metastatic to the lung when the cells were injected i.v. These observations indicate that platelet-aggregating activity is ...
Ativity 25 - PCC - Portland Community College
Ativity 25 - PCC - Portland Community College

... • http://www.nhlbi.nih.gov/health/dci/Diseases/Hbp/HBP_WhatIs.html ...
the universe within - The Learning Centers at Fairplex
the universe within - The Learning Centers at Fairplex

... The exhibit educationally and artfully displays approximately 200 organs, human bodies and other anatomical specimens. OUR BODY: THE UNIVERSE WITHIN allows your students to learn about their own bodies and, ultimately, teaches them how to take better care of themselves and make positive lifestyle ch ...
Cellular Force Microscopy for in Vivo
Cellular Force Microscopy for in Vivo

... small indentation scans covering several cells, and cell wall puncture using very high forces. The mechanical effects of turgor pressure were investigated by mapping cell apparent stiffness in various states of plasmolysis as well as by comparing stiffness before and after releasing turgor pressure ...
Introduction-to-OBO - Buffalo Ontology Site
Introduction-to-OBO - Buffalo Ontology Site

... ontologies must be developed within the Foundry framework • We welcome the development of competing approaches to open-access ontology development – which can only make the Foundry stronger ...
The programme of cell death in plants and animals – A comparison
The programme of cell death in plants and animals – A comparison

... cell death (PCD) in plants has been attempted. PCD and its mechanism are fairly well known in animals than in plants. The available information indicates that out of eight categories of cells that undergo PCD, only six are known in plants. The mechanism of PCD in the different categories of plant ce ...
Inmunol 27-4
Inmunol 27-4

... et al. proposed that infection would be detected by innate receptors for microbiological biomolecules that are either absent or different in mammals. These agents were found to stimulate antigen presenting cells in such a way that would provide T lymphocytes with appropriate costimulatory molecules ...
Parathyroid Gland – Introduction
Parathyroid Gland – Introduction

... Tinctorial properties of the cytoplasm vary, and the presence of clear or dark cells reflects different functional status of the chief cells. Chief cells in the mouse parathyroid may be clear or dark, with an increase in clear cells in older mice. Cytoplasmic volume or nuclear density of the chief c ...
Metabolic Incorporation of Stable Isotope Labels into Glycans
Metabolic Incorporation of Stable Isotope Labels into Glycans

... during their existence1,3 and virtually all membrane and secreted proteins are glycosylated.2 Glycoprotein glycans often play crucial roles in physiological events such as cell-cell recognition,4-6 signal transduction,7 inflammation8 and tumorigenesis.9-13 Given the important physiological roles of ...
O 2 , CO 2
O 2 , CO 2

... Fig 42.11 ...
Respiratory System
Respiratory System

... • Emphysema - damage to air sacs walls causing loss of elasticity; • Pleurisy - inflammation of the pleural membrane lining lungs and the chest cavity; • Lung Cancer - malignant tumors that develop in lung tissue • Acute Bronchitis-inflammation of the bronchial tubes; • Influenza - serious infection ...
The Dielectric Response of Spherical Live Cells in Suspension: An
The Dielectric Response of Spherical Live Cells in Suspension: An

... Dielectric spectroscopy has been successfully used in the past to characterize biological matter (1–8). These types of measurements probe the collective dielectric response of many live cells in suspensions or in tissues, but by using more or less elaborated models, useful information about the stat ...
Basic and Translational Research Program
Basic and Translational Research Program

... The goal of the Hoffman-Kim laboratory is to understand axon guidance in complex environments and inform biomaterial and tissue engineering strategies for promoting nerve regeneration. We apply engineering techniques to biological systems in vitro to challenge growing neurons with multiple guidance ...
Cardiovascular System
Cardiovascular System

... • Approximately 1 percent of cardiac cells do not function in contraction, but have specialized features that are essential for normal heart excitation. • These cells constitute a network known as the conducting system of the heart and are in electrical contact with the cardiac muscle cells via gap ...
PDF
PDF

... maintain commitments to their lineages, as shown by studies of their development in clonal cultures (e.g. Rutz and Hauschka, 1982) or by transplanting them singly to new positions in the embryo (Wylie et al. 1987). Commitment could depend upon the activity of relatively few specific regulatory 'line ...
| Medical nanoparticles for next generation drug delivery to the lungs
| Medical nanoparticles for next generation drug delivery to the lungs

... The lung is a unique organ for drug delivery. Its large surface area, thin epithelium layer and rich blood supply ensure fast drug absorption. These properties offer not only the possibility to treat lung disease, but also allow for the systemic application of drugs. Levels of metabolism in the lung ...
CLEP Biology - Problem Drill 15: Animal Function Question No. 1 of
CLEP Biology - Problem Drill 15: Animal Function Question No. 1 of

... Specific immunity has specificity and memory. It provides resistance to specific invaders. It contains two interactive immune response: 1. The humoral immune response: -- Detects antigens in blood stream -- Involves antibodies generated by B-cells 2. The cellular immune response: -- Detect antigens ...
Inhibition of Staphylococcus aureus biofilm formation using AIP
Inhibition of Staphylococcus aureus biofilm formation using AIP

... biofilms, which can cause problems within the devices and lead to infection. Catheter-related bloodstream infections can increase hospital costs by over $50,000 for each patient. ...
Systematic profiling of cellular phenotypes with spotted cell
Systematic profiling of cellular phenotypes with spotted cell

... each spot. As an initial proof-of-concept, we first performed genomewide differential interference contrast (DIC) imaging to examine the effects of deleting each yeast gene on basic aspects of cellular morphology such as cell shape, size, budding pattern and clumping, from which we expected to find ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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