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LIGHT MICROSCOPIC STUDY OF PORELLA PLATYPHYLLA (L
LIGHT MICROSCOPIC STUDY OF PORELLA PLATYPHYLLA (L

... -80°C. The reason for this is that the longer and slower freezing process could cause the formation of large ice crystals which destroy membrane systems and organelles too. Cells were unimpaired after the rapid and short frost effect at -80°C. When the cells were coloured with neutral red before fre ...
50116Xm1Review
50116Xm1Review

... Clinical Cancer in Patients Clinical Trials (Phase I, Phase II, and Phase III) Dr. Steve Graziano: Lung Cancer Therapy (Last week of class) ...
Fluid, Electrolyte and Acid
Fluid, Electrolyte and Acid

... Movement of solute and solvent across a membrane caused by hydrostatic (water pushing) pressure Occurs at the capillary level If normal pressure gradient changes (as occurs with right-sided heart failure) edema results from “third spacing” ...
Respiratory AnimPhysio20151
Respiratory AnimPhysio20151

... pleural space • Edema of pleural cavity • Possible causes: – blockage of lymphatic drainage – cardiac failure-increased capillary filtration P – reduced plasma colloid osmotic pressure – infection/inflammation of pleural surfaces which breaks down capillary membranes ...
filtration of a bacterial fermentation broth: harvest conditions
filtration of a bacterial fermentation broth: harvest conditions

... component from cell surface after 5 hours of aging would enhance the magnitude of charge repulsion between cells and as a consequence decrease the specific hydraulic resistance of B2 and B3 aged broths. For broth aged at pH 4, the value predicted for the cake hydraulic resistance is much lower than ...
Human skin
Human skin

...  sympathetic fibers  along the blood vessels  sensory fibers  rami glandulares of rami perforantes of the intercostal nerves  rr. mammarii mediales  rr. cutanei anteriores II-VI intercostal nerve  rr. mammarii laterales  rr. cutanei lateralis IV-VI intercostal nerve Prof. Dr. Nikolai Lazarov ...
file - Athens Academy
file - Athens Academy

...  visceral peritoneum: covers organs of the peritoneal cavity  parietal peritoneum: lines peritoneal cavity  visceral pericardium: covers surface of heart  parietal pericardium: lines pericardial cavity  visceral pleura: covers surface of lungs  parietal pleura: lines pleural cavity Coelomic fl ...
Patients Cell Development Reminiscent to SCID IL
Patients Cell Development Reminiscent to SCID IL

... To analyze the effect of IL-10 overexpressed by APCs as observed in some SCID patients, we have expressed the human IL-10 cDNA under the control of the murine MHC class II promoter in transgenic mice. Similar to SCID patients, these mice presented a defect in T cell maturation characterized by a rap ...
The Role of the MDI and DPI in Pediatric Patients
The Role of the MDI and DPI in Pediatric Patients

... are not required, clinical trials testing these devices are rarely carried out prior to approval. For a holding chamber, the device must be shown in in vitro modeling studies to deliver drug similarly (quantity, particle size) to the properly used, unaided MDI. This must include study of only 3 MDI ...
The A6B4 Integrin Can Regulate ErbB-3 Expression: Implications for
The A6B4 Integrin Can Regulate ErbB-3 Expression: Implications for

... first evidence that a6h4 contributes to the functions of carcinoma cells and they elucidated some of the mechanisms involved. Specifically, these studies identified key roles for a6h4 in the migration, invasion, and survival of carcinoma cells (7–9). Studies by several other laboratories have substa ...
PHLEBOTOMY INTRO The Vascular System The vascular
PHLEBOTOMY INTRO The Vascular System The vascular

... The veins that form the M-shaped venous distribution pattern include the cephalic vein, median vein, median cephalic vein, median basilic vein, and basilic vein. The veins most commonly used for venipuncture in this distribution pattern are described as follows: • Median vein (also called the interm ...
File - thebiotutor.com
File - thebiotutor.com

...  Cell membranes are partially permeable (only some substances can diffuse across). Diffusion of gases in leaves:  CO2 diffuses into the leaf through the stomata from the air. It then travels to the palisade leaf cells and diffuse into them to be part of photosynthesis.  O2 from photosynthesis and ...
The Ability to Form Primary Tumor Xenografts is Predictive of
The Ability to Form Primary Tumor Xenografts is Predictive of

... compared to cell lines and murine allografts (3, 5). However, there are also limitations to the model including loss of species-specific tumor cell-stromal interface and differences in pharmacokinetic and pharmacodynamic interactions, that potentially may limit their predictive value in drug develop ...
histology of muscle tissues and types
histology of muscle tissues and types

... thick middle layer between the outer epicardium layer and the inner endocardium layer. The pulmonary artery helps to fulfil the function of exchange between cardiac muscle cells. The primary structural proteins of cardiac muscle are myosin and actin. The cardiac muscle cells are typically branch-lik ...
Acute Renal Failure
Acute Renal Failure

... 1. Expansion of extracellular fluid volume. 2. Hyperkalemia is a frequent complication of ARF; Coexistent metabolic acidosis may exacerbate hyperkalemia by promoting potassium efflux from cells. Hyperkalemia may be particularly severe, even at the time of diagnosis, in patients with rhabdomyolysis, ...
LYMPHATIC SYSTEM
LYMPHATIC SYSTEM

... -Carbonic acid formed in filtrate dissociates to release carbon dioxide and water - Carbon dioxide then diffuses into tubule cells, where it acts to trigger further hydrogen ion secretion - For each hydrogen ion secreted, a sodium ion and a bicarbonate ion are reabsorbed by the PCT cells - Secreted ...
Fluid-Phase Endocytosis in Plant Cells
Fluid-Phase Endocytosis in Plant Cells

... have been identified in animal systems, some of which are just beginning to be uncovered in plant cells. By definition and operational design, all types of endocytosis (whether clathrin-mediated, caveolin-mediated, lipid raft-dependent, flotillin-dependent, and micro- or macropinocytosis; Moscatelli ...
Gamma delta T cell responses associated with the development of
Gamma delta T cell responses associated with the development of

... and this profile predicted the subsequent development of TB. Gamma delta T cell involvement during TB infection has been demonstrated by the presence of specific Vc9/ Vd2 T cells in children with TB and this was associated with increased proliferation of these cells, reduced IFNc production and granul ...
CA Circulatory L
CA Circulatory L

... aorta remains closed because of higher pressure in the left & right aorta (higher than in the right ventricle). • As a result, the right aorta receives blood from the left aorta (so both aortas carry oxygenated blood) and blood from the right ventricle (low in oxygen) passes only into the pulmonary ...
Respiratory Epithelium, Larynx and Trachea
Respiratory Epithelium, Larynx and Trachea

...  Its function is to clean, moisten and warm the inhaled air and conduct it to respiratory part. Respiratory unit ...
7-2 Eukaryotic Cell Structure
7-2 Eukaryotic Cell Structure

... In many plant cells there is a single, large central vacuole filled with liquid. The pressure of the central vacuole allows plants to support heavy structures such as leaves and flowers. ...
Rapid analysis of the extracellular matrix protein decorin using the
Rapid analysis of the extracellular matrix protein decorin using the

... Decorin is found in connective tissue where, among other roles, it helps to regulate cell growth by interacting with growth factors and collagen. After cloning of full-length human decorin cDNA into the pQE-TriSystem vector, human fibrosarcoma cells (HT-1080) were transfected, and the expression of ...
Gram Positive Bacteria Marker (3811): sc-58136
Gram Positive Bacteria Marker (3811): sc-58136

... Bacteria cells are classified as Gram-positive if they retain a crystal violet dye during the Gram stain process. Gram-positive bacteria appear blue or violet under a microscope after the stain has been applied, whereas Gramnegative bacterial look red or pink. This difference in color is mainly due ...
File - Mrs. Barrett`s Biology Site
File - Mrs. Barrett`s Biology Site

... Internal transport in small animals is by diffusion and active transport e.g. amoeba, jellyfish and flatworms whereas bigger and more complex animals e.g. humans need a vascular system. Open circulatory system – blood leaves the blood vessels. Blood is pumped into open-ended vessels. The blood then ...
Anatomy and Physiology - Columbus City Schools
Anatomy and Physiology - Columbus City Schools

... plant physiology are important for food production and for commercial industries, but also for maintaining healthy ecosystems and even global climate since plants consume carbon dioxide (a greenhouse gas) during photosynthesis. Society directly benefits from applications of physiology as a disciplin ...
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Organ-on-a-chip

An organ-on-a-chip (OC) is a multi-channel 3-D microfluidic cell culture chip that simulates the activities, mechanics and physiological response of entire organs and organ systems. It constitutes the subject matter of significant biomedical engineering research, more precisely in bio-MEMS. The convergence of labs-on-chips (LOCs) and cell biology has permitted the study of human physiology in an organ-specific context, introducing a novel model of in vitro multicellular human organisms. One day, they will perhaps abolish the need for animals in drug development and toxin testing.Although multiple publications claim to have translated organ functions onto this interface, the movement towards this microfluidic application is still in its infancy. Organs-on-chips will vary in design and approach between different researchers. As such, validation and optimization of these systems will likely be a long process. Organs that have been simulated by microfluidic devices include the heart, the lung, kidney, artery, bone, cartilage, skin and more.Nevertheless, building valid artificial organs requires not only a precise cellular manipulation, but a detailed understanding of the human body’s fundamental intricate response to any event. A common concern with organs-on-chips lies in the isolation of organs during testing. ""If you don’t use as close to the total physiological system that you can, you’re likely to run into troubles"" says William Haseltine, founder of Rockville, Maryland. Microfabrication, microelectronics and microfluidics offer the prospect of modeling sophisticated in vitro physiological responses under accurately simulated conditions.
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