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Role of N-Ras in Renal Fibrosis
Role of N-Ras in Renal Fibrosis

Systems biology of virus-host signaling network
Systems biology of virus-host signaling network

... model had greater predictive power than the literature-derived network, while reducing the total number of connections, suggesting that many interactions found in the literature were not functional in the specific experimental system considered (i.e., liver hepatocarcinoma cells) (18). Similarly, ex ...
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... et al., 2001). In extension of this data, we now also determined the accumulation kinetics of the two less strongly, but likewise unequivocally accumulating compounds, 1 and 11, in cell-wall extracts from Pst-infected A. thaliana leaves, using 10 as reference (Fig. 4). Similar to 10, both 1 and 11 b ...
Isolation of Spherosomes with Lysosome Characteristics from
Isolation of Spherosomes with Lysosome Characteristics from

... activity after separation of the particulate compo­ nents from the soluble material indicates the pos­ sibility of an interaction between hydrolases and soluble factors. In fact the high speed supernatant contains an inhibitory factor for acid protease and phosphatase as demonstrated by determ inati ...
Full-Text PDF
Full-Text PDF

... mouse macrophages as well as in HeLa cells. The acetylation of H3K9 as well as trimethylation of H3K4 on the Il6 and Il12b, but not Cxcl1 and Tnf promoters was induced in response to LPS in an Akirin2-dependent manner. These data suggested the involvement of promoter specific or stimulus specific re ...
88th Inaugural Lecture - University of Port Harcourt
88th Inaugural Lecture - University of Port Harcourt

... development, until he turned his attention to neuroscience in the late 1970s. (Crick, 1988; Sherborn, 1995; Strathern, 1997). ...
Isolation of Spherosomes with Lysosome
Isolation of Spherosomes with Lysosome

... activity after separation of the particulate compo­ nents from the soluble material indicates the pos­ sibility of an interaction between hydrolases and soluble factors. In fact the high speed supernatant contains an inhibitory factor for acid protease and phosphatase as demonstrated by determ inati ...
Text
Text

... of the body cavities define three fluid-filled cavities: the peritoneal, pleural and pericardial cavities. These serous cavities constitute important reservoirs of innate-like B-cell subsets, also called B1 cells, the major innate function of which is to ensure early immune protection from infection by ...
Article - Research | www.stowers.org
Article - Research | www.stowers.org

... matic reduction of the apical cell surface area (Figures 1A–1C) also apparent at the level of the basal SJs, as seen by labeling with an antibody against Discs-large (Dlg) (not shown). Whereas the MF is characterized by an acute decrease in the apical cell surface of over 10 cell diameters, the who ...
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... the oxygen consumption of C. albicans while the silver complexes increase oxygen consumption. In addition, pregrowth of cells in the copper complexes resulted in a lower ergosterol content while the silver complexes induced an elevation in ergosterol synthesis. The ability of copper and silver compl ...
Cancer-Initiating Cells from Colorectal Cancer Patients Escape from
Cancer-Initiating Cells from Colorectal Cancer Patients Escape from

Untitled - University of Guelph
Untitled - University of Guelph

... because an RNA-interference-induced decrease in Arabidopsis AIP1 levels lowers F-actin turnover while promoting actin bundling [51]. In both the AIP1 and the ADF1 studies, increased F-actin bundling is associated with inhibition of cell expansion [51,52]. Although several actin-bundling proteins of ...
traffic jams affect plant development and signal transduction
traffic jams affect plant development and signal transduction

... Although the basic machinery for vesicular transport is conserved among all eukaryotic cells, the plant endomembrane system also has unique components. In mammals and yeast, each cell has only one type of vacuole, whereas in plants, different types of vacuole — lytic and protein storage — frequently ...
Two classic cadherin-related molecules with no cadherin
Two classic cadherin-related molecules with no cadherin

... may be required to shape a complex body that is composed of many different cell populations. The V-form cadherin genes are classified into type I and type II on the basis of phylogenetic differences (Takeichi, 1995). The type I cadherins are expressed rather ubiquitously, whereas the type II cadheri ...
16A Leonard Hall
16A Leonard Hall

... In VIII 03-29 g, h, j SPAN 351, 402, 451, change ‘so the proposals …Spanish Department’ to ‘within a short period of time so the department will be asked to select another open number.’ In IX 03-32 a, b move ‘Sechrist’ to read ‘with Sechrist abstaining,’ and add (which was approved at the last meeti ...
Myc Requires Distinct E2F Activities to Induce S Phase
Myc Requires Distinct E2F Activities to Induce S Phase

... in media containing low serum and harvested at the indicated times. The percentage of surviving cells was calculated; the mean values and standard deviations are shown. (B) Annexin staining assays. Wild-type and E2F1⫺/⫺ MEFs were transfected with 2 ␮g of CMV-GFP and either 5 ␮g of control vector or ...
Developmental roles of Rhomboid proteases
Developmental roles of Rhomboid proteases

... metalloproteases that reside on the plasma membrane. In contrast, expression of rhomboid1 is extremely restricted and dynamic [18–20]. In fact, there is a strict correlation between the expression pattern of Rhomoid1 and the activation of the EGFR pathway as monitored by staining for phosphorylated ...
Vacuole Membrane Protein 1 Is an Endoplasmic
Vacuole Membrane Protein 1 Is an Endoplasmic

... and expel water by transient fusion with the plasma membrane (Gabriel et al., 1999). Contractile vacuole biogenesis is dependent on clathrin-coated vesicles and the adaptor-protein complex 1 (AP-1) for transporting protein and membranes required for the CV formation (O’Halloran and Anderson, 1992; L ...
The PXY-CLE41 receptor ligand pair defines a
The PXY-CLE41 receptor ligand pair defines a

... in plant meristems has come from studies of the vascular meristem where the highly ordered nature of vascular development makes it an excellent system for studying the mechanisms that control the orientation of cell division. In contrast to initials in apical meristems, vascular initials are long th ...
Plant PCD In vegetative development Suspensor degradation
Plant PCD In vegetative development Suspensor degradation

... CMS A long noncoding RNA regulates photoperiod-sensitive male sterility, an essential component of hybrid rice(2012) doi: 10.1073/pnas.1121374109 A non-coding RNA locus mediates environment-conditioned male sterility in rice. (2012) Cell Research 22:791–792. doi:10.1038/cr.2012.43 Comparative expres ...
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... k-fibers are under tension, leaving us with a paradox about the origin of the curved shape of the spindle. Let us imagine that something connects sister k-fibers and makes them follow a smooth arc. What could this structure be? The type of material that is able to link k-fibers in such a way must be of ...
A Cytochemical Study of the Stem Cell Concept in Specimens o£ a
A Cytochemical Study of the Stem Cell Concept in Specimens o£ a

... TEXT-FIG. 1. The frequency distributions of the relative amounts of DNA in the interphase nuclei o[ five tumor specimens (A to E) compared with the distribution of the diploid DNA values of interphase ]ymphocytes. Each tumor specimen (Specimens A to E) is shown individually with the DNA distribution ...
The pollen wall and tapetum are altered in the
The pollen wall and tapetum are altered in the

... but was acetolysis sensitive (Aarts et al., 1997; Ariizumi et al., 2003). The early stages of microsporocyte meiosis and primexine deposition appeared to occur normally in the RC7 line. At the tetrad stage, primexine appeared to be deposited on the microspores based on the regular undulation of the ...
Review Convergent Extension - Massachusetts Institute of Technology
Review Convergent Extension - Massachusetts Institute of Technology

... Continued examination of all of the movements and cellular mechanisms in many different organisms will be needed to appreciate the regulatory logic and evolutionary constraints that determine the form of the vertebrate embryo. Frogs and Fish Use Different Cellular Mechanisms to Accomplish Convergent ...
Shewanella oneidensis MR-1 chemotaxis proteins and electron
Shewanella oneidensis MR-1 chemotaxis proteins and electron

... electron transfer along extracellular appendages known as microbial nanowires [11–13]; and (iv) extracellular matrices containing conductive or semi-conductive minerals [14]. Given that survival of the cells may well be dependent upon EET, it would be surprising if a number of solutions to this prob ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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