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Condensin II Promotes the Formation of Chromosome Territories by
Condensin II Promotes the Formation of Chromosome Territories by

... Condensin II is required to inhibit the Rabl configuration and to disperse heterologous centromeres We next sought to determine if nurse cell CTs were consistent with the Rabl configuration in which the centromeric regions of all chromosomes cluster together near the nuclear periphery and the telome ...
Cell shrinkage and apoptosis: a role for potassium and sodium ion
Cell shrinkage and apoptosis: a role for potassium and sodium ion

... alterations in the membrane fluidity and permeability during apoptosis were determined. As in previous reports (Lennon et al, 1991; Martin and Cotter, 1991), when exponentially growing HL-60 cell cultures were exposed to cytotoxic agents or UV irradiation virtually all cells undergo apoptosis, displ ...
The many ways to age for a single yeast cell
The many ways to age for a single yeast cell

... endonuclease G NUC1) and an unusual form of autophagy that resembles PCD-associated megaautophagy in plants. Besides these roles during sexual and asexual reproduction, additional physiological scenarios associated with PCD in yeast have been described, among which ageing has drawn most attention in ...
Synthesis and sorting of proteoglycans
Synthesis and sorting of proteoglycans

... interactions, normally of ionic nature, with growth factors, for example. Recent studies have identified ~30 PG protein cores. These cores are not just scaffolds for GAGs: they contain domains that have particular biological activities (Iozzo, 1998). Many PGs are thus multifunctional molecules that ...
1-1 Test Bank Huether: Understanding Pathophysiology, 4th Edition
1-1 Test Bank Huether: Understanding Pathophysiology, 4th Edition

... 30. What causes the rapid change in the resting membrane potential that initiates an action potential? A. Potassium gates open, and potassium rushes into the cell changing the membrane potential from negative to positive. B. Sodium gates open, and sodium rushes into the cell changing the membrane po ...
Two distinct classes of prestalk
Two distinct classes of prestalk

reviews - London Health Sciences Centre
reviews - London Health Sciences Centre

... It has long been recognized that some types of cancer show an organ-specific pattern of metastasis. Breast cancer frequently metastasizes to bone, liver, brain and lungs; prostate cancer preferentially spreads to bone. Patients with colorectal cancer, by contrast, often develop initial metastases in ...
Microbial Discovery Activity
Microbial Discovery Activity

... Some students proposed modifications to the exercise to develop it further and make it more difficult. They proposed creating pictures of the various cell parts (which could be created ahead of time by the students themselves, or could be provided by the teacher as actual micrographs) that could be ...
Organelle Trail - cloudfront.net
Organelle Trail - cloudfront.net

... 1. CRIME: What has this organelle done?  Why is this organelle "wanted"? In other words, what does it do for the cell? Or, what is the organelle’s function? 2. PHYSICAL DESCRIPTION: What does the organelle look like?  Provide a description and an actual picture. The picture can be a mug shot (prin ...
MUC1 is a novel costimulatory molecule of human T cells and
MUC1 is a novel costimulatory molecule of human T cells and

... through phosphorylation of transcription factors [18]. In the original studies [8], it was demonstrated that MUC1 was only expressed on a fraction of activated T cells at a given time. Once matured with mitogens, MUC1 was determined to have coinhibitory capabilities in highly purified T-cell cultures ...
A Novel Role of Annexin A2 in Human Type I Collagen Gene
A Novel Role of Annexin A2 in Human Type I Collagen Gene

... two 20 ml aliquots were removed for EMSA analysis [one aliquot did not receive any probe to confirm removal of the probe (i.e., binding to the beads), while the other aliquot was replenished with an appropriate amount of probe to confirm removal of DNAbinding protein complexes]. The protein-DNA-strept ...
introduction - Macmillan Learning
introduction - Macmillan Learning

... After returning from a summer vacation, he injected some chickens with an old culture. The chickens became ill, but, to Pasteur’s surprise, they recovered. Pasteur then grew a fresh culture of the bacterium with the intention of injecting it into some fresh chickens. But, as the story goes, his supp ...
Mitochondrial alternative oxidase acts to dampen the generation of
Mitochondrial alternative oxidase acts to dampen the generation of

... Plant material and growth conditions The suspension cells used were derived from leaves of wt or transgenic tobacco (Nicotiana tabacum L. cv. Petit Havana SR1) and had been in culture for approximately 5 years prior to this study (Vanlerberghe et al. 1994). The transgenic cells (AS8) constitutively ...
S1 Topic 8 The Basic Structure of a Cell
S1 Topic 8 The Basic Structure of a Cell

...  understand and use the English terms related to the basic structure of a cell (e.g., structure, cell, cell membrane, cell wall, cytoplasm, nucleus) and the functions of different parts of a cell (e.g., controls activities, contains DNA, carries information, produce new cells, what goes in, what go ...
NIH Public Access - McArdle Laboratory for Cancer Research
NIH Public Access - McArdle Laboratory for Cancer Research

... B6 recipient mice were given a single dose of TCDD one day prior to transplant and were then euthanized on post-operative days (POD) 10 or 16, or at the time of rejection (Figure 1A). Compared to untreated (median GST=10 days), no graft loss from rejection was seen in the TCDD-treated group in the f ...
Lipid Map of the Mammalian Cell
Lipid Map of the Mammalian Cell

... when the lipid tails are turned away from water and water molecules have maximum freedom (the ‘hydrophobic effect’), PC molecules assemble into a bilayer. The typical PC carries one saturated and one unsaturated chain. It yields a fluid (‘liquid crystalline’) membrane with many characteristics of bi ...
Non-Flagellar Swimming in Marine Synechococcus
Non-Flagellar Swimming in Marine Synechococcus

... cell-surface components that may be involved in swimming, a major polypeptide of 130 kDa was identified whose decrease in abundance following brief proteinase K treatment of actively swimming cells coincided with the loss of motility (Brahamsha, 1996a). A survey of motile and nonmotile marine Synech ...
Choose your fate: artery, vein or lymphatic vessel?
Choose your fate: artery, vein or lymphatic vessel?

... diseases. This review focuses on recent advances in embryonic vascular development research, particularly the elucidation of molecular mechanisms that are involved in the development of specialized arteriovenous or lymphatic cell lineages. ...
PDF
PDF

... fusomes were detected, but only among germ cells at some distance from ectopic hub cells (Fig. 4D, arrow). Strikingly, germ cells adjacent to ectopic hub cells often contained dot fusomes (Fig. 4D, arrowheads). As the ectopic cells were several tiers removed from the endogenous hub, these data stron ...
Memoryless self-reinforcing directionality in endosomal active
Memoryless self-reinforcing directionality in endosomal active

... likelihood estimation. The range of the power-law tail does not depend on how the data are binned to calculate the distributions (Fig. 3c, inset). It spans the entire length scale that is physically reasonable: from the smallest possible step size, which is the individual run length, to the largest ...
At work: Finding out about Amoeba Copymaster Information Finding
At work: Finding out about Amoeba Copymaster Information Finding

... in amoeba: amoeba: the the contractile vacuole vacuole .. It It becomes becomes bigger bigger and smaller smaller at after a short time. The contractile vacuole helps to prevent this: it takes up the water that flows in, and regular regular intervals intervals10.. The contractile vacuole is is very ...
Pseudoautosomal genes in man - Development
Pseudoautosomal genes in man - Development

... Shapiro & Mohandas (1986). The regional localizIn families ascertained at random, we have found a ation of the MIC2 gene on the Y chromosome was single X/Y recombination event including MIC2 in 46 achieved by in situ hybridization using the pSGl informative male meiosis. Testing the same families pr ...
PDF
PDF

... mice in each case). The percentage of cells in which the centroid of the ciliated area was in the anterior quadrant peaked at P9 (Fig. 1F). The density of the basal bodies also changed during differentiation. Whereas the cell area was slightly larger at P9 than at P7 and the adult stage (Fig. 1G), t ...
3 | cell structure and function
3 | cell structure and function

... are used for locomotion. Pili are used to exchange genetic material during a type of reproduction called conjugation. Fimbriae are protein appendages used by bacteria to attach to other cells. ...
Recruitment of lymphocytes to the human liver
Recruitment of lymphocytes to the human liver

... expressed on endothelial cells capture fast moving lymphocytes from the bloodstream. These receptors may be members of either the selectin family of adhesion proteins27 or the immunoglobulin superfamily.28–30 Once captured, the adherent cell detects activating messages presented in the form of chemo ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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