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Neuron
Neuron

... the bicommissural space. FEF, frontal eye field; LIP, lateral intraparietal; DP, dorsal prelunate; as, arcuate sulcus; ips, intraparietal sulcus; L, left. (B) Multiple activity peaks along the intraparietal sulcus revealed by the group analysis. Activity map is superimposed on coronal MRI sections ( ...
Somatotopic mapping of natural upper- and lower
Somatotopic mapping of natural upper- and lower

... Yet a limitation of the HGM approach applied in previous experimental studies is that, like ESM, it crucially relies on active patient cooperation and compliance over an extended time period. This may be difficult to achieve in infants, small children, and in cognitively impaired individuals, or if e ...
Anatomofunctional organization of the ventral primary motor and
Anatomofunctional organization of the ventral primary motor and

... The ventral agranular frontal cortex of the macaque monkey is formed by a mosaic of anatomically distinct areas. Although each area has been explored by several neurophysiological studies, most of them focused on small sectors of single areas, thus leaving to be clarified which is the general anatom ...
Mirror neurons in monkey area F5 do not adapt to the observation of
Mirror neurons in monkey area F5 do not adapt to the observation of

... from IT cortex of anesthetized11 as well as of awake behaving monkeys9 have not been able to lend support to this latter hypothesis. Conceptually, an interesting question is whether adaptation to visual stimulation is confined to visual neurons located in striate and extrastriate visual cortex or whe ...
Methods of Studying The Nervous System
Methods of Studying The Nervous System

... Electrical Recording Methods • Multiple unit recording – Multiple unit recording provides an indication of the rate of firing of many neurons in the general vicinity of the electrode tip – An electrode larger than a microelectrode picks up the action potentials from many nearby neurons – The signal ...
Preparation for action: one of the key functions of motor cortex.
Preparation for action: one of the key functions of motor cortex.

... result has been interpreted as a strong argument in favor of the hypothesis that providing prior information intervenes during processes of movement preparation or planning, but not during those of movement execution. The use of the preparatory paradigm makes it thus possible, first, to dissociate i ...
the premotor cortex of the monkey
the premotor cortex of the monkey

... msec allowed from the onset time of the go signal to reach the target key (part 4, Fig. 1). Depression of the target key, regardless of whether it was rewarded, was followed by one of eight randomly determined “intertrial intervals” (0.8 to 2.4 set) during which the monkey was required to continue d ...
Role of the trigeminal mesencephalic nucleus in rat whisker pad
Role of the trigeminal mesencephalic nucleus in rat whisker pad

... macrovibrisae showed that whisking neurons similar to those observed in the trigeminal ganglion were located in the TMnu. These neurons had different patterns of activation, which were dependent on the type of spontaneous macrovibrissae movement. In particular, their spiking activity tonically incre ...
Temporal and spatial alterations in GPi neuronal encoding might
Temporal and spatial alterations in GPi neuronal encoding might

... from each electrode was sorted and classified on-line using a templatematching algorithm (Worgotter et al., 1986), implemented by a PCbased spike sorter (MSD, Alpha-Omega Engineering, Nazareth, Israel). The spike trains detected by this system, as well as the behavioral events and other measurements ...
Mirror Neurons: Findings and Functions
Mirror Neurons: Findings and Functions

... After the first experiment, a great amount of research has provided evidence for the location of the MNS and its properties. This research has shown that there appear to be other areas with mirror properties. Besides the premotor area, one of its important input areas, the rostral inferior parietal ...
Crapse (2008) Corollary discharge across the animal kingdom
Crapse (2008) Corollary discharge across the animal kingdom

... that is caused by external agents (for example, when something hits you). It is critical for nervous systems to be able to differentiate between these two scenarios. A ubiquitous strategy is to route copies of movement commands to sensory structures. These signals, which are referred to as corollary ...
Neurons in red nucleus and primary motor cortex exhibit similar
Neurons in red nucleus and primary motor cortex exhibit similar

... was implanted over the stereotaxic coordinates of the RN. The recording chamber was centered on the midline and angled 35◦ posterior of vertical, which allowed us to identify the superior and inferior colliculus during penetrations into the rostral and caudal RN, respectively. Neural data was collec ...
optimal feedback control and the neural basis of volitional motor
optimal feedback control and the neural basis of volitional motor

... adjustments to stabilize the body. Neural recordings from monkeys are often used to examine how the activity of individual neurons relates to sensorimotor function. The anatomical and physiological properties of the limbs9,41 and CNS are similar across primates42,43, and species such as Macaca mulat ...
Mirror Proposal 8-01 - USC - University of Southern California
Mirror Proposal 8-01 - USC - University of Southern California

... developing. F5 canonical neurons select via re-afferent connections visual neurons describing a variety of surfaces. Only those selected become AIP neurons that code affordances. Visual Feedback for Grasping: A Possible Precursor of the Mirror Property: We offer a new hypothesis for the generalizati ...
Tracking Whole-Brain Connectivity Dynamics in the Resting State
Tracking Whole-Brain Connectivity Dynamics in the Resting State

... Considering the strong evidence for fluctuations in FC, how then should we best investigate spontaneous variations in the framework of a large group study? In contrast to investigations with task designs or paced experimental manipulations, the variety of mental states experienced during rest and the ...
decision-making in the primate brain
decision-making in the primate brain

... shift gaze to one of two possible target locations in order to receive a fruit juice reward. A change from yellow to red indicated that looking to the upper target would be rewarded while a change from yellow to green indicated that the lower target would be rewarded. In successive blocks of trials, ...
Towards the integration of neural mechanisms and cognition in
Towards the integration of neural mechanisms and cognition in

... How intelligence arises in humans is far to be completely unveiled. Understanding the brain mechanisms that make it possible is one of the most interesting and debated topics in neuroscience. However, recent advances speculate about that this is only half part of the story. Intelligent behaviours in ...
Studies of the Role of the Paramedian Pontine Reticular Formation
Studies of the Role of the Paramedian Pontine Reticular Formation

... It is surprising that issues about the on-direction of cells in PPRF are still unresolved 30 years after chronic unit recording methods allowed the first descriptions of pontine cells with saccade-related and eye-position–related activity.9–12 However, untrained subjects were used in early experimen ...
Dexterous Finger Movements in Primate Without Monosynaptic
Dexterous Finger Movements in Primate Without Monosynaptic

... Because the ability to perform skilled finger movements with the hand has likewise increased during development, it was suggested that the monosynaptic corticomotoneuronal (CM; henceforth referred to as direct CM) connection might play a decisive role in this control (Bernhard and Bohm 1954). In beh ...
Brain Electrical Activity During Waking and Sleep States
Brain Electrical Activity During Waking and Sleep States

... is stimulated via implanted electrodes in sleeping animals, behavioral awakening and EEG desynchronization result. This is also true in animals after section of the long ascending sensory systems in the mesencephalon but does not occur after lesions of the mesencephalic RF. Indeed, after extensive l ...
EEG Biofeedback, Hemoencephalography Biofeedback and
EEG Biofeedback, Hemoencephalography Biofeedback and

... Migraine is a common, disabling and often progressive disorder characterized by increased excitability  of the central nervous system .1,2   It occurs in 18%of women and 6% of men in the US with peak  prevalence in individuals between the ages of 25 and 55.3 Economic burden of migraine in the US is  ...
Evidence for a distributed hierarchy of action
Evidence for a distributed hierarchy of action

... transport them, and hold them quite differently to use them. In addition, individual motor elements can be adjusted in advance, based on the desired outcome. Gentilucci, Negrotti, and Gangitano (1997) showed that when a person reaches and picks up an object, then places it on a second target, the ini ...
Brain Electrical Activity During Waking and Sleep States
Brain Electrical Activity During Waking and Sleep States

... stimulated via implanted electrodes in sleeping animals, behavioral awakening and EEG desynchronization result. This is also true in animals after section of the long ascending sensory systems in the mesencephalon but does not occur after lesions of the mesencephalic RF. Indeed, after extensive lesi ...
Nucleus Basalis and Thalamic Control of Neocortical Activity in the
Nucleus Basalis and Thalamic Control of Neocortical Activity in the

... rats. Surgery was performed under deep anesthesia induced by a mixture (4 ml/kg) of ketamine (25 mg/ml), rompun (1.3 mg/ml), and acepromazine (0.25 m&ml). The rat was placed in the stereotaxic apparatus with bregma and lambda in the same horizontal plane. For mapping studies, 18 holes were drilled i ...
Chronic multiunit recordings in behaving animals: advantages and
Chronic multiunit recordings in behaving animals: advantages and

... fMRI does not accurately reflect the spiking activity of neurons in a particular brain area but seems to be related more to the input coming from other brain structures (Logothetis et al., 2001). Till date, the golden standard to investigate the way information is processed within brain structures s ...
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Brain–computer interface

A brain–computer interface (BCI), sometimes called a mind-machine interface (MMI), direct neural interface (DNI), or brain–machine interface (BMI), is a direct communication pathway between the brain and an external device. BCIs are often directed at assisting, augmenting, or repairing human cognitive or sensory-motor functions.Research on BCIs began in the 1970s at the University of California, Los Angeles (UCLA) under a grant from the National Science Foundation, followed by a contract from DARPA. The papers published after this research also mark the first appearance of the expression brain–computer interface in scientific literature.The field of BCI research and development has since focused primarily on neuroprosthetics applications that aim at restoring damaged hearing, sight and movement. Thanks to the remarkable cortical plasticity of the brain, signals from implanted prostheses can, after adaptation, be handled by the brain like natural sensor or effector channels.Following years of animal experimentation, the first neuroprosthetic devices implanted in humans appeared in the mid-1990s.
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