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New developments in preventing and managing hypertension
New developments in preventing and managing hypertension

... Getting older is a nonmodifiable risk factor for high blood pressure. It is likely that systolic blood pressure will rise13 and this is thought to mirror the length of time that people have been exposed to modifiable risk factors.14 Women tend to have a lower blood pressure than men up to the age of ...
Comparison of Red Cell and Whole Blood Volume as
Comparison of Red Cell and Whole Blood Volume as

... treated as normal distributions and compared with the paired t test. The plasma volume distribution was not normal. Its skewness was within 2 standard deviations of skewness for a sample size of 27 and could thus be treated as a symmetrical distribution and compared using the Wilcoxon signed rank te ...
Value of ABCD in Predicting Cerebral Ischemic Attacks: Three
Value of ABCD in Predicting Cerebral Ischemic Attacks: Three

... Abstract- Cerebrovascular attack (CVA) and transient ischemic attack (TIA) are major causes of emergency department visits around the globe. A significant number of these patients may experience repeat attacks if left untreated. Several risk stratifying scoring systems have been developed in recent ...
Adenosine Diphosphate–Induced Platelet Aggregation
Adenosine Diphosphate–Induced Platelet Aggregation

... (data not shown). To further study the association between the H2 haplotype and ADP-stimulated platelet aggregation, we randomly selected 10 carriers and 10 noncarriers of the H2 haplotype. As ADP-induced platelet aggregation is considered to be dependent on the extracellular Ca2⫹ concentration,17 w ...
The Renin–Angiotensin– Aldosterone System: Approaches to
The Renin–Angiotensin– Aldosterone System: Approaches to

... renal function. It has been demonstrated that Levels of tumor necrosis factor α are dogs with severe compensatory mitral valve increased in congestive heart failure, causdisease receiving enalapril for 2 years had no ing left ventricular dilation and remodeling. statistical difference in serum ure ...
Allergology International Vol.53 No.4
Allergology International Vol.53 No.4

... Chusid et al.1 are as follows: (i) a persistent eosinophilia of 1500 /µL for longer than 6 months; (ii) lack of evidence of any known cause of eosinophilia; and (iii) evidence of organ system involvement. Many diseases are associated with various degrees of eosinophilia.2 The present patient had no ...
Hemoglobinopathies
Hemoglobinopathies

... members. DNA testing is not routinely done but can be used to help diagnose hemoglobin variants, thalassemia, and to determine carrier ...
here - Cobalt Development Institute
here - Cobalt Development Institute

... thyroid and polycythemic effects were reversible upon cessation of oral cobalt treatment. Doses lower than 3 milligrams per kilogram body weight were not reported to induce thyroid effects in children. Currently, the clinical use of cobalt for the treatment of anaemia has been replaced by the use of ...
Blood group A
Blood group A

... An adult human has about 4–6 liters of blood circulating in the body. Blood consists of several types of cells floating around in a fluid called plasma. The red blood cells (RBCs) contain haemoglobin, a protein that binds oxygen. RBCs transport oxygen to, and remove carbon dioxide from the tissues. ...
Blood group A
Blood group A

... An adult human has about 4–6 liters of blood circulating in the body. Blood consists of several types of cells floating around in a fluid called plasma. The red blood cells (RBCs) contain haemoglobin, a protein that binds oxygen. RBCs transport oxygen to, and remove carbon dioxide from the tissues. ...
Task 1b) Preparing the blood agar
Task 1b) Preparing the blood agar

... amikacine ...


... Patients. Twenty patients with JCML were studied. Clinical data of the patients are listed in Table 1. The diagnosis of JCML was based on a synthesis of data from physical and laboratory examinations,includinghepatosplenomegaly,increasedWBCcountswith all stages of granulocytic differentiation and wi ...
METHODS Scanning Electron Microscopy (SEM) Coded samples
METHODS Scanning Electron Microscopy (SEM) Coded samples

... designation followed by the name and GenBank accession number of the best-matching sequence, percent sequence identity and finally the number of sequences of this type is shown at the end of each branch. Three GELOTUs, one closely related to Treponema sp, are ...
The Blood Group Systems Inheritance and Genetics
The Blood Group Systems Inheritance and Genetics

... Several methods for testing the ABO group of an individual exist. The most common method is: Serology: This is a direct detection of the ABO antigens. It is the main method used in blood transfusion centres and hospital blood banks. This form of testing involves two components: a) Antibodies that a ...
Dynamics of Leukocyte-Platelet Adhesion in Whole
Dynamics of Leukocyte-Platelet Adhesion in Whole

... largest percentage of unactivated “baseline” binding, followed by PMN and lymphocytes. These numbers compare favorably with previously reported results of binding of unstimulated isolated cell fractions, except for monocytes, which showed a lesser bound percentage in whole blood compared with recomb ...
Direct Intravascular Blood Volume Analysis
Direct Intravascular Blood Volume Analysis

... Clinical research has proven that intravascular blood volume measurement represents a critical consideration for diagnosis and treatment of several acute and chronic conditions. Published studies from leading institutions such as the Cleveland Clinic, Yale University School of Medicine, and Columbia ...
How to approach chronic anemia Mark J. Koury and Melissa Rhodes
How to approach chronic anemia Mark J. Koury and Melissa Rhodes

... normal shortly after birth. Serum ferritin, which reflects total body iron stores, will be normal or elevated, further distinguishing the thalassemia trait from iron deficiency. When a definitive diagnosis of 1 or 2 ␣-globin gene deletions is desired for treatment or genetic counseling, ␣-globin gen ...
Caring for patients who refuse blood
Caring for patients who refuse blood

... Websites and resources  ...
lymphatic vessels
lymphatic vessels

... The picture shows The capsule (C) of the spleen connects to trabeculae (T) which partially subdivide the pulp—like interior of the organ. The red pulp (R) occupies most of the parenchyma, with white pulp (W) restricted to smaller areas, mainly around the central arterioles. ...
Results - BioMed Central
Results - BioMed Central

... available since the 1960s. In adults, reference ranges are the same for all ages despite evidence that erythrocyte count and haemoglobin concentration start to decline in men around 40 years of age; age-associated changes in women are less marked [1]. The World Health Organisation defines anaemia as ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... ocleidomastoid muscle and their insertion points into the clavicle, the internal jugular vein bound with the caroti d artery in the carotid sheath, runs deep to the sternocleidomastoid muscle and emerges between the two heads o f this muscle before passing deep to the clavicle to join the subclavian ...
Blood Donation - Some Facts
Blood Donation - Some Facts

... only platelets, which are special cells in the blood used by your body to heal wounds and clot blood, and the rest is returned to your body. This type of donation is open to experienced donors with adequate veins and high platelet counts. The collection process is similar to whole blood donation, bu ...
Cardio-Cerebral Diseases - MedCrave Online Publishing Group
Cardio-Cerebral Diseases - MedCrave Online Publishing Group

... syndrome that involves left ventricular apical akinesis and mimics acute coronary syndrome. It was first described in Japan in 1990 by Sato et al. [58]. Patients often present with chest pain, have ST-segment elevation on electrocardiogram, and elevated cardiac enzyme levels consistent with a myocar ...
- LSHTM Research Online
- LSHTM Research Online

... and MCH [5,8]. Subtle effects such as these might be hard to discern in SCD, where blood parameters are expected to primarily reflect diseaserelated processes, such as variable degrees of anemia, leukocytosis, and thrombocytosis [11–14]. HbF levels in SCD are also affected by the disease itself. The ...
Infectious Etiologies of Acute Febrile Illness among
Infectious Etiologies of Acute Febrile Illness among

... illness (AFI) etiologies in tropical regions challenge diagnosis, treatment, and public health responses to endemic and epidemic diseases. Further confounding this is the fact that a majority of the patients present with non-descript symptoms (e.g., low-grade fever, general malaise, headache, and mu ...
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Hemolytic-uremic syndrome



Hemolytic-uremic syndrome (or haemolytic-uraemic syndrome), abbreviated HUS, is a disease characterized by hemolytic anemia (anemia caused by destruction of red blood cells), acute kidney failure (uremia), and a low platelet count (thrombocytopenia). It predominantly, but not exclusively, affects children. Most cases are preceded by an episode of infectious, sometimes bloody, diarrhea acquired as a foodborne illness or from a contaminated water supply and caused by E. coli O157:H7, although Shigella, Campylobacter and a variety of viruses have also been implicated. It is now the most common cause of acquired acute renal failure in childhood. It is a medical emergency and carries a 5–10% mortality; of the remainder, the majority recover without major consequences but a small proportion develop chronic kidney disease and become reliant on renal replacement therapy.The primary target appears to be the vascular endothelial cell. This may explain the pathogenesis of HUS, in which a characteristic renal lesion is capillary microangiopathy.HUS was first defined as a syndrome in 1955. The more common form of the disease, Shiga-like toxin-producing E. coli HUS (STEC-HUS), is triggered by the infectious agent E. coli O157:H7. Certain Shiga toxin secreting strains of Shigella dysenteriae can also cause HUS. Approximately 5% of cases are classified as pneumococcal HUS, which results from infection by Streptococcus pneumoniae, the agent that causes traditional lobar pneumonia. There is also a rare, chronic, and severe form known as atypical hemolytic uremic syndrome (aHUS), which is caused by genetic defects resulting in chronic, uncontrolled complement activation. Both STEC-HUS and aHUS cause endothelial damage, leukocyte activation, platelet activation, and widespread inflammation and multiple thromboses in the small blood vessels, a condition known as systemic thrombotic microangiopathy (TMA), which leads to thrombotic events as well as organ damage/failure and death.
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