Administration of cyclosporine for 24 months
... they previously had acute GVHD or if a skin biopsy showed histological evidence of subclinical GVHD. Patients were excluded if they had manifestations of clinical extensive chronic GVHD, recurrent malignant disease, serum creatinine levels above 177 mol/L (2.0 mg/dL) or more than twice the normal v ...
... they previously had acute GVHD or if a skin biopsy showed histological evidence of subclinical GVHD. Patients were excluded if they had manifestations of clinical extensive chronic GVHD, recurrent malignant disease, serum creatinine levels above 177 mol/L (2.0 mg/dL) or more than twice the normal v ...
ch 21 Blood Vessels
... 1. The volume that flows through any tissue in a given period of time is blood flow. 2. The velocity of blood flow is inversely related to the cross-sectional area of blood vessels; blood flows most slowly where cross-sectional area is greatest (Figure 21.11). 3. Blood flow decreases from the aorta ...
... 1. The volume that flows through any tissue in a given period of time is blood flow. 2. The velocity of blood flow is inversely related to the cross-sectional area of blood vessels; blood flows most slowly where cross-sectional area is greatest (Figure 21.11). 3. Blood flow decreases from the aorta ...
your lab focus
... heparin in vivo than is actually the case, leading to dose reductions and a corresponding risk of recurrent thrombosis. Alternatively, an artifactually shortened clotting time would typically cause the physician to inappropriately increase the anticoagulant dose, putting the patient at risk for hemo ...
... heparin in vivo than is actually the case, leading to dose reductions and a corresponding risk of recurrent thrombosis. Alternatively, an artifactually shortened clotting time would typically cause the physician to inappropriately increase the anticoagulant dose, putting the patient at risk for hemo ...
Vascular Injury: Overview Hemostasis Hemostasis Blood vessels
... Adhesion • Coating of subendothelial collagen by von Willebrand factor accelerates adhesion by a receptor-mediated process – Platelet GPIb binds to vWF on the damaged surface ...
... Adhesion • Coating of subendothelial collagen by von Willebrand factor accelerates adhesion by a receptor-mediated process – Platelet GPIb binds to vWF on the damaged surface ...
End Points of Resuscitation
... early indicator of complications (ongoing hemorrhage, ACS) – Effects of ethanol, drugs, seizures, bicarbonate on BD level should be considered when using this end point ...
... early indicator of complications (ongoing hemorrhage, ACS) – Effects of ethanol, drugs, seizures, bicarbonate on BD level should be considered when using this end point ...
Ed Harris – My Story - Scleroderma Education Project
... Armed with a vastly improved way to do medical research, I located some little known research studies from the Netherlands that showed a very significant finding about scleroderma that appears to have been missed by virtually all scleroderma researchers at that time. It turns out that in sclerod ...
... Armed with a vastly improved way to do medical research, I located some little known research studies from the Netherlands that showed a very significant finding about scleroderma that appears to have been missed by virtually all scleroderma researchers at that time. It turns out that in sclerod ...
Transfusion Medicine: A History
... Furthering the work of Lewisohn and Weil, Rous and Turner developed a solution of salt, isocitrate and dextrose in order to both anticoagulate and preserve blood. This mixture made the blood extremely dilute, so it had to be removed prior to transfusion. (1:1 solution:blood ratio) This method, with ...
... Furthering the work of Lewisohn and Weil, Rous and Turner developed a solution of salt, isocitrate and dextrose in order to both anticoagulate and preserve blood. This mixture made the blood extremely dilute, so it had to be removed prior to transfusion. (1:1 solution:blood ratio) This method, with ...
Platelets Kinase Released from Activated Human Caused by
... Complement component C3 has been shown to be phosphorylated in vitro by at least five different protein kinases, in different domains of the molecule and with different biologic effects. The C3a moiety of C3 is known to be phosphorylated by PKA and PKC (11) as well as by an ecto-protein kinase from ...
... Complement component C3 has been shown to be phosphorylated in vitro by at least five different protein kinases, in different domains of the molecule and with different biologic effects. The C3a moiety of C3 is known to be phosphorylated by PKA and PKC (11) as well as by an ecto-protein kinase from ...
57 INFLAMMATORY RESPONSE IN INFECTIVE ENDOCARDITIS E
... started, the higher the rate of survival and the lower the rate of complications. Diagnosis of blood culture negative endocarditis (BCNE) is very difficult and not always possible. BCNE occurs in 2.5-31% of IE cases (6). The Duke criteria perform poorly in these patients (34). In such cases a proper ...
... started, the higher the rate of survival and the lower the rate of complications. Diagnosis of blood culture negative endocarditis (BCNE) is very difficult and not always possible. BCNE occurs in 2.5-31% of IE cases (6). The Duke criteria perform poorly in these patients (34). In such cases a proper ...
* Bleeding Disorders * Approach a Child with Purpura * Hematology
... HSP: •Prognosis: •Complete recovery is the rule unless ...
... HSP: •Prognosis: •Complete recovery is the rule unless ...
УДК: 619:615
... experimental animals, which were carried nitrate load, starting from the 10th day of the experiment. Thus, in animal experimental group E1 enzyme activity was 0,361±0,14 mmol/l/h., whereas in the control group it was 0,379±0,10 mmol/l/h that is the AsAT activity increased by 4.7%. On the 30th day of ...
... experimental animals, which were carried nitrate load, starting from the 10th day of the experiment. Thus, in animal experimental group E1 enzyme activity was 0,361±0,14 mmol/l/h., whereas in the control group it was 0,379±0,10 mmol/l/h that is the AsAT activity increased by 4.7%. On the 30th day of ...
Ambiguous Phenotypes and Genotypes in 16
... all samples were mixed with diploid mononuclear cells from normal blood donors ...
... all samples were mixed with diploid mononuclear cells from normal blood donors ...
Anatomical description of double left suprarenal vein and its
... the double LSRV (normal and variant) were identified, both tributaries from the left renal vein. The normal LSRV measured 3 cm up to the renal vein whereas the variant LSRV was 7.5 cm long. The latter was also thinner, started on the lateral border of the suprarenal and went down adjacent to the ren ...
... the double LSRV (normal and variant) were identified, both tributaries from the left renal vein. The normal LSRV measured 3 cm up to the renal vein whereas the variant LSRV was 7.5 cm long. The latter was also thinner, started on the lateral border of the suprarenal and went down adjacent to the ren ...
The Use and Abuse of Self Monitoring of Blood Glucose
... the eyes (retinopathy), kidneys (nephropathy), and peripheral nerves (neuropathy) and large blood vessel complications of the heart (causing heart attacks), head and neck (causing strokes), and legs (leading to gangrene and amputations). Diabetic retinopathy is the leading cause of blindness in indu ...
... the eyes (retinopathy), kidneys (nephropathy), and peripheral nerves (neuropathy) and large blood vessel complications of the heart (causing heart attacks), head and neck (causing strokes), and legs (leading to gangrene and amputations). Diabetic retinopathy is the leading cause of blindness in indu ...
The Use and Abuse of Self Monitoring of Blood Glucose
... the eyes (retinopathy), kidneys (nephropathy), and peripheral nerves (neuropathy) and large blood vessel complications of the heart (causing heart attacks), head and neck (causing strokes), and legs (leading to gangrene and amputations). Diabetic retinopathy is the leading cause of blindness in indu ...
... the eyes (retinopathy), kidneys (nephropathy), and peripheral nerves (neuropathy) and large blood vessel complications of the heart (causing heart attacks), head and neck (causing strokes), and legs (leading to gangrene and amputations). Diabetic retinopathy is the leading cause of blindness in indu ...
Antiphospholipid Antibodies
... in the general population, which occurs more commonly before 10 weeks of pregnancy. Additionally, APLAs are associated with other pregnancy complications, including eclampsia, preeclampsia, and placental insufficiency. A woman is considered to have had a clinical event that meets the Sapporo criteri ...
... in the general population, which occurs more commonly before 10 weeks of pregnancy. Additionally, APLAs are associated with other pregnancy complications, including eclampsia, preeclampsia, and placental insufficiency. A woman is considered to have had a clinical event that meets the Sapporo criteri ...
Inherited platelet-based bleeding disorders
... Inherited platelet-based bleeding disorders include abnormalities of platelet number (inherited thrombocytopenias) and function (inherited disorders of platelet function) (Table 1). Some disorders are characterized by both thrombocytopenia and abnormalities of platelet function. Inherited disorders ...
... Inherited platelet-based bleeding disorders include abnormalities of platelet number (inherited thrombocytopenias) and function (inherited disorders of platelet function) (Table 1). Some disorders are characterized by both thrombocytopenia and abnormalities of platelet function. Inherited disorders ...
Case Studies - Oxford Academic
... Herein, we report the case of a patient with an infrequent hereditary arrangement of 4 various genetic anomalies of hemoglobin genes: the patient and her husband had 3 mutations on the α-gene and a sickle-cell anomaly on the β-gene, which is a rare combination.9,10 The co-occurrence of sickle-cell a ...
... Herein, we report the case of a patient with an infrequent hereditary arrangement of 4 various genetic anomalies of hemoglobin genes: the patient and her husband had 3 mutations on the α-gene and a sickle-cell anomaly on the β-gene, which is a rare combination.9,10 The co-occurrence of sickle-cell a ...
I. Blood Collection - Austin Community College
... Written materials are given to the donor which explains high risk activities which may make the donor ineligible Donor must be informed and give consent that blood will be used for others unless they are in a special donor category First time donors must provide proof of identification such as SS#, ...
... Written materials are given to the donor which explains high risk activities which may make the donor ineligible Donor must be informed and give consent that blood will be used for others unless they are in a special donor category First time donors must provide proof of identification such as SS#, ...
Molecular Mechanism of a Mild Phenotype in Coagulation Factor XIII
... A-subunit deficiency are umbilical bleeding in the neonatal period and repeated fetal wastage in pregnant females.1-3 Generally, most of the patients require lifelong substitution therapy to prevent serious bleeding complications. About 200 cases of FXIII deficiency have been reported,3 and the gene ...
... A-subunit deficiency are umbilical bleeding in the neonatal period and repeated fetal wastage in pregnant females.1-3 Generally, most of the patients require lifelong substitution therapy to prevent serious bleeding complications. About 200 cases of FXIII deficiency have been reported,3 and the gene ...
Activation-induced cell death in T lymphocytes from multiple
... Freshly isolated PBMC were washed twice with PBS and blocked for 10 min at room temperature in blocking solution (PBS with 10% of fetal bovine serum). Cells were then incubated with specific antibodies for 25 min at room temperature with shaking. The following antibodies were used: phycoerythrin (PE) ...
... Freshly isolated PBMC were washed twice with PBS and blocked for 10 min at room temperature in blocking solution (PBS with 10% of fetal bovine serum). Cells were then incubated with specific antibodies for 25 min at room temperature with shaking. The following antibodies were used: phycoerythrin (PE) ...
Lymphatic System The lymphatic system and the cardiovascular
... are closely related structures that are joined by a capillary system. The lymphatic vessels are present wherever there are blood vessels and transport excess fluid to the end vessels without the assistance of any "pumping" action. The lymphatic system is composed of lymph vessels, lymph nodes, and o ...
... are closely related structures that are joined by a capillary system. The lymphatic vessels are present wherever there are blood vessels and transport excess fluid to the end vessels without the assistance of any "pumping" action. The lymphatic system is composed of lymph vessels, lymph nodes, and o ...
Blood managemenT, TransfusIons and surgerY
... doctor about autologous donation and to weigh the associated risks, costs and benefits. Many elective surgeries do not require blood transfusions, and about half of all autologous units that are collected are never used. Unused autologous donations are discarded. Blood banks can collect your blood b ...
... doctor about autologous donation and to weigh the associated risks, costs and benefits. Many elective surgeries do not require blood transfusions, and about half of all autologous units that are collected are never used. Unused autologous donations are discarded. Blood banks can collect your blood b ...
Passive Reporting Underestimates Rate of Platelet
... Platelet-Associated TACO (continued from page 1) designated as TACO. However, proactive evaluation and surveillance of reactions revealed that TACO occurred in two patients who were not reported to the transfusion service. Their reactions were characterized by new-onset hypertension, crackles on lun ...
... Platelet-Associated TACO (continued from page 1) designated as TACO. However, proactive evaluation and surveillance of reactions revealed that TACO occurred in two patients who were not reported to the transfusion service. Their reactions were characterized by new-onset hypertension, crackles on lun ...
Advances in Environmental Biology County
... and iron absorption from the gastrointestinal tract increases. Patients with thalassemia major often followed by ineffective blood production have a high iron absorption from the gastrointestinal tract. Iron, in the presence of superoxide and hydrogen peroxide generated in cells, produces cells dama ...
... and iron absorption from the gastrointestinal tract increases. Patients with thalassemia major often followed by ineffective blood production have a high iron absorption from the gastrointestinal tract. Iron, in the presence of superoxide and hydrogen peroxide generated in cells, produces cells dama ...
Hemolytic-uremic syndrome
Hemolytic-uremic syndrome (or haemolytic-uraemic syndrome), abbreviated HUS, is a disease characterized by hemolytic anemia (anemia caused by destruction of red blood cells), acute kidney failure (uremia), and a low platelet count (thrombocytopenia). It predominantly, but not exclusively, affects children. Most cases are preceded by an episode of infectious, sometimes bloody, diarrhea acquired as a foodborne illness or from a contaminated water supply and caused by E. coli O157:H7, although Shigella, Campylobacter and a variety of viruses have also been implicated. It is now the most common cause of acquired acute renal failure in childhood. It is a medical emergency and carries a 5–10% mortality; of the remainder, the majority recover without major consequences but a small proportion develop chronic kidney disease and become reliant on renal replacement therapy.The primary target appears to be the vascular endothelial cell. This may explain the pathogenesis of HUS, in which a characteristic renal lesion is capillary microangiopathy.HUS was first defined as a syndrome in 1955. The more common form of the disease, Shiga-like toxin-producing E. coli HUS (STEC-HUS), is triggered by the infectious agent E. coli O157:H7. Certain Shiga toxin secreting strains of Shigella dysenteriae can also cause HUS. Approximately 5% of cases are classified as pneumococcal HUS, which results from infection by Streptococcus pneumoniae, the agent that causes traditional lobar pneumonia. There is also a rare, chronic, and severe form known as atypical hemolytic uremic syndrome (aHUS), which is caused by genetic defects resulting in chronic, uncontrolled complement activation. Both STEC-HUS and aHUS cause endothelial damage, leukocyte activation, platelet activation, and widespread inflammation and multiple thromboses in the small blood vessels, a condition known as systemic thrombotic microangiopathy (TMA), which leads to thrombotic events as well as organ damage/failure and death.