Gerald F. DiBona Sympathetic Nervous System and Hypertension
... (glomerular) damage. The effects of renal denervation on renal hemodynamics, renal function, and urinary albumin excretion were examined in 100 consecutive resistant hypertensive patients.14 Renal denervation decreased blood pressure, renal resistive index, and incidence of albuminuria without adver ...
... (glomerular) damage. The effects of renal denervation on renal hemodynamics, renal function, and urinary albumin excretion were examined in 100 consecutive resistant hypertensive patients.14 Renal denervation decreased blood pressure, renal resistive index, and incidence of albuminuria without adver ...
Plasma cell leukemia: consensus statement on diagnostic
... cells, and exclude other lymphoproliferative diseases, including low-grade B-cell or lymphoplasmacytic lymphoma. Do we need both an absolute value of circulating plasma cells and a percentage of WBC? The criteria developed by Kyle2, requiring both more than 20% circulating plasma cells and an absolu ...
... cells, and exclude other lymphoproliferative diseases, including low-grade B-cell or lymphoplasmacytic lymphoma. Do we need both an absolute value of circulating plasma cells and a percentage of WBC? The criteria developed by Kyle2, requiring both more than 20% circulating plasma cells and an absolu ...
Low urinary indoxyl sulfate levels early after transplantation reflect a
... Department of Hematology and Oncology, Internal Medicine III, University Medical Center, Regensburg, Germany; 2Institute of Functional Genomics, University of Regensburg, Regensburg, Germany; 3Institute of Clinical Microbiology and Hygiene and 4Department of Orthopedic Surgery, University Medical Ce ...
... Department of Hematology and Oncology, Internal Medicine III, University Medical Center, Regensburg, Germany; 2Institute of Functional Genomics, University of Regensburg, Regensburg, Germany; 3Institute of Clinical Microbiology and Hygiene and 4Department of Orthopedic Surgery, University Medical Ce ...
Pain, purpura and curly hairs
... A 43-year-old man was referred to dermatology after presenting to the accident and emergency department with leg pain, swelling and rash. The purpuric rash had developed over the preceding 4 weeks. He had no history of trauma or recent illness, and was otherwise well at presentation. He had a histor ...
... A 43-year-old man was referred to dermatology after presenting to the accident and emergency department with leg pain, swelling and rash. The purpuric rash had developed over the preceding 4 weeks. He had no history of trauma or recent illness, and was otherwise well at presentation. He had a histor ...
Shorter deferral periods for blood donation
... It may not be possible to provide evidence in support of the efficacy of PRT in preventing disease transmission in a clinical setting due to the substantial amount of data required for this type of study. Therefore, the efficacy of PRT was measured in terms of the logarithmic reduction in blood comp ...
... It may not be possible to provide evidence in support of the efficacy of PRT in preventing disease transmission in a clinical setting due to the substantial amount of data required for this type of study. Therefore, the efficacy of PRT was measured in terms of the logarithmic reduction in blood comp ...
Therapeutic Apheresis in Children
... BE DONE. A drug history should be obtained; donors who have taken aspirin or aspirin containing medications within 3 days of donation should be temporarily deferred ...
... BE DONE. A drug history should be obtained; donors who have taken aspirin or aspirin containing medications within 3 days of donation should be temporarily deferred ...
Hypertension and Anaesthesia
... adverse peri-operative myocardial event has been the focus of numerous studies. Prys-Roberts and colleagues showed an increase in arrhythmias and post-operative myocardial infarction in a small population of hypertensive patients during the early 1970s.7 Goldman and Caldera, in 1979, looked at a lar ...
... adverse peri-operative myocardial event has been the focus of numerous studies. Prys-Roberts and colleagues showed an increase in arrhythmias and post-operative myocardial infarction in a small population of hypertensive patients during the early 1970s.7 Goldman and Caldera, in 1979, looked at a lar ...
Hereditary spherocytosis, elliptocytosis, and other red cell
... be ruled out in 96.9% of the cases). This test is able to detect HS due to defects in band 3, spectrin and 4.2 but less effective for HS due to ankyrin defects.70 The test can also be positive in pyropoikilocytosis (HPP) due to significant extent of cell fragmentation leading to generation of red cel ...
... be ruled out in 96.9% of the cases). This test is able to detect HS due to defects in band 3, spectrin and 4.2 but less effective for HS due to ankyrin defects.70 The test can also be positive in pyropoikilocytosis (HPP) due to significant extent of cell fragmentation leading to generation of red cel ...
What Determines Blood Vessel Structure? Genetic Prespecification
... Formation of the vascular tree is the result of a complex interplay between genetic factors and epigenetic factors including hemodynamics and tissue oxygenation. The process of cardiovascular development occurs in two steps, vasculogenesis and then vascular remodeling. During vasculogenesis, cells a ...
... Formation of the vascular tree is the result of a complex interplay between genetic factors and epigenetic factors including hemodynamics and tissue oxygenation. The process of cardiovascular development occurs in two steps, vasculogenesis and then vascular remodeling. During vasculogenesis, cells a ...
New disease perspectives and goals of therapy in CLL
... and CD43) along with CD5, an antigen normally found on T cells. Typically, CLL cells also express surface immunoglobulin (slg), CD79b, CD20, and CD22 at low density.4,11 The phenotypic features of CLL are not only used for initial diagnosis, but they also play a role in the assessment of minimal res ...
... and CD43) along with CD5, an antigen normally found on T cells. Typically, CLL cells also express surface immunoglobulin (slg), CD79b, CD20, and CD22 at low density.4,11 The phenotypic features of CLL are not only used for initial diagnosis, but they also play a role in the assessment of minimal res ...
Blood Typing
... with one RBC antigen: the Rh antigen. (In actuality, there are several separate Rh antigens, but we’re only going to worry about one of them, called RhD). The Rh antigen got its name because it was first described in the blood cells of rhesus monkeys. Simply speaking, either your blood cells have th ...
... with one RBC antigen: the Rh antigen. (In actuality, there are several separate Rh antigens, but we’re only going to worry about one of them, called RhD). The Rh antigen got its name because it was first described in the blood cells of rhesus monkeys. Simply speaking, either your blood cells have th ...
blood - Quia
... Blood contains genetically determined proteins Antigens (a substance the body recognizes as foreign) may be attacked by the immune system Antibodies are the “recognizers” Blood is “typed” by using antibodies that will cause blood with certain proteins to clump (agglutination) ...
... Blood contains genetically determined proteins Antigens (a substance the body recognizes as foreign) may be attacked by the immune system Antibodies are the “recognizers” Blood is “typed” by using antibodies that will cause blood with certain proteins to clump (agglutination) ...
- Wiley Online Library
... population. We did not find any differences in major transplant outcomes, including acute (≥Grade II) and chronic GVHD, NRM, and OS between secretors and nonsecretors. Our data therefore do not suggest a clinically significant effect of secretor status on a donor-derived humoral immune response agai ...
... population. We did not find any differences in major transplant outcomes, including acute (≥Grade II) and chronic GVHD, NRM, and OS between secretors and nonsecretors. Our data therefore do not suggest a clinically significant effect of secretor status on a donor-derived humoral immune response agai ...
and Coding of Complications
... • Ileus occurs after almost all abdominal surgeries – physiologic response – all patients treated NPO and then advanced in diet when bowel activity returns • Ileus occurs with all patients with abdominal trauma and perforation caused by the trauma or any perforation or infected process – that’s ...
... • Ileus occurs after almost all abdominal surgeries – physiologic response – all patients treated NPO and then advanced in diet when bowel activity returns • Ileus occurs with all patients with abdominal trauma and perforation caused by the trauma or any perforation or infected process – that’s ...
Multiple Alleles: Modeling of Blood Groups and its Applications
... (3) Chronological Background of Rh factor Blood group: The ABO blood group isn't the only aspect of our blood type chemistry. There are about a dozen known genes which affect "blood type" activity. Because the ABO blood type has been known the longest, and has such a powerful effect, it is the one w ...
... (3) Chronological Background of Rh factor Blood group: The ABO blood group isn't the only aspect of our blood type chemistry. There are about a dozen known genes which affect "blood type" activity. Because the ABO blood type has been known the longest, and has such a powerful effect, it is the one w ...
Diagnostic Accuracy of Stool Assays for Inflammatory Bacterial
... Because acute bacterial gastroenteritis is often inflammatory, rapid stool assays that detect intestinal inflammation might be used to distinguish between bacterial and nonbacterial gastroenteritis. We performed metaanalyses to determine the discriminatory power, in developed and in resource-poor co ...
... Because acute bacterial gastroenteritis is often inflammatory, rapid stool assays that detect intestinal inflammation might be used to distinguish between bacterial and nonbacterial gastroenteritis. We performed metaanalyses to determine the discriminatory power, in developed and in resource-poor co ...
Effect of Oral Nimodipine on Platelet Function
... nimodipine had no effect on plasma TXB2 concentrations21; this finding also supports nimodipine's lack of in vivo effect in ischemia. The effect of nimodipine on platelets in normal, healthy, young control subjects may be different from that in older patients with active vascular disease. For instan ...
... nimodipine had no effect on plasma TXB2 concentrations21; this finding also supports nimodipine's lack of in vivo effect in ischemia. The effect of nimodipine on platelets in normal, healthy, young control subjects may be different from that in older patients with active vascular disease. For instan ...
Inova Blood Donor Services
... Your blood type is determined by the presence of specific antibodies found on the surface of red blood cells. There are four main blood types: O, A, B and AB. Your blood also carries an Rh factor that is positive or negative. Together, that gives us 8 possible blood variations. Women typically have ...
... Your blood type is determined by the presence of specific antibodies found on the surface of red blood cells. There are four main blood types: O, A, B and AB. Your blood also carries an Rh factor that is positive or negative. Together, that gives us 8 possible blood variations. Women typically have ...
Total white blood cell count, liver enzymes, and
... hospitalizations have had conflicting results (4,5). Only age is consistently positively correlated with the rate of MetS in patients with schizophrenia (6). Research on the biological correlates of MetS in schizophrenia must be improved. Hematologic parameters such as the total white blood cell (WB ...
... hospitalizations have had conflicting results (4,5). Only age is consistently positively correlated with the rate of MetS in patients with schizophrenia (6). Research on the biological correlates of MetS in schizophrenia must be improved. Hematologic parameters such as the total white blood cell (WB ...
Use of Beta-Blockers In patients With Diabetes Mellitus
... • Post-MI beta-blockade reduces mortality by 23% in diabetic patients. • In CHF studies, β-blockers have consistently shown a significant benefit in patients with ...
... • Post-MI beta-blockade reduces mortality by 23% in diabetic patients. • In CHF studies, β-blockers have consistently shown a significant benefit in patients with ...
Exercise and hypertension
... with pre-existing atherosclerotic vascular disease. However, the absolute risk of sudden death during any particular episode of heavy exercise is low (1 sudden death per 1.5 million episodes of exertion) and, reassuringly, habitual heavy exercise did attenuate the relative risk of sudden death that ...
... with pre-existing atherosclerotic vascular disease. However, the absolute risk of sudden death during any particular episode of heavy exercise is low (1 sudden death per 1.5 million episodes of exertion) and, reassuringly, habitual heavy exercise did attenuate the relative risk of sudden death that ...
trait (minor), 100% for beta-thalassemia major and variable
... γ2) and just before birth to adult Hb A (a2β2). At 6 months after birth, HbF comprises less than 5% of total Hb and reaches adult level at 2 years of age43. Clinically severe forms of betathalassemia become apparent on completion of the switch from fetal to adult Hb. The majority of beta-thalassemia ...
... γ2) and just before birth to adult Hb A (a2β2). At 6 months after birth, HbF comprises less than 5% of total Hb and reaches adult level at 2 years of age43. Clinically severe forms of betathalassemia become apparent on completion of the switch from fetal to adult Hb. The majority of beta-thalassemia ...
Hot Topic 4
... individual patient and wider costs to society. It is therefore desirable to take measures to limit transfusion and to clearly define the indications for transfusion. In the past the approach has been the aim to maintain a haemoglobin concentration above 100g/l, with higher levels often aimed for in ...
... individual patient and wider costs to society. It is therefore desirable to take measures to limit transfusion and to clearly define the indications for transfusion. In the past the approach has been the aim to maintain a haemoglobin concentration above 100g/l, with higher levels often aimed for in ...
First case report of blood and urine cultures positive bacteraemia by
... Following sample collection, the patient was immediately given empirical treatment with parenteral ceftriaxone (2 g twice daily) in anticipation that the patient was suffering from typhoid fever; most of the recent S. Typhi Kolkata isolates had shown decreased susceptibility to ciprofloxacin (Dutta ...
... Following sample collection, the patient was immediately given empirical treatment with parenteral ceftriaxone (2 g twice daily) in anticipation that the patient was suffering from typhoid fever; most of the recent S. Typhi Kolkata isolates had shown decreased susceptibility to ciprofloxacin (Dutta ...
Hemolytic-uremic syndrome
Hemolytic-uremic syndrome (or haemolytic-uraemic syndrome), abbreviated HUS, is a disease characterized by hemolytic anemia (anemia caused by destruction of red blood cells), acute kidney failure (uremia), and a low platelet count (thrombocytopenia). It predominantly, but not exclusively, affects children. Most cases are preceded by an episode of infectious, sometimes bloody, diarrhea acquired as a foodborne illness or from a contaminated water supply and caused by E. coli O157:H7, although Shigella, Campylobacter and a variety of viruses have also been implicated. It is now the most common cause of acquired acute renal failure in childhood. It is a medical emergency and carries a 5–10% mortality; of the remainder, the majority recover without major consequences but a small proportion develop chronic kidney disease and become reliant on renal replacement therapy.The primary target appears to be the vascular endothelial cell. This may explain the pathogenesis of HUS, in which a characteristic renal lesion is capillary microangiopathy.HUS was first defined as a syndrome in 1955. The more common form of the disease, Shiga-like toxin-producing E. coli HUS (STEC-HUS), is triggered by the infectious agent E. coli O157:H7. Certain Shiga toxin secreting strains of Shigella dysenteriae can also cause HUS. Approximately 5% of cases are classified as pneumococcal HUS, which results from infection by Streptococcus pneumoniae, the agent that causes traditional lobar pneumonia. There is also a rare, chronic, and severe form known as atypical hemolytic uremic syndrome (aHUS), which is caused by genetic defects resulting in chronic, uncontrolled complement activation. Both STEC-HUS and aHUS cause endothelial damage, leukocyte activation, platelet activation, and widespread inflammation and multiple thromboses in the small blood vessels, a condition known as systemic thrombotic microangiopathy (TMA), which leads to thrombotic events as well as organ damage/failure and death.