Vancomycin-resistant enterococcal bacteremia: comparison of
... Three patients presented with disseminated intravascular coagulation. The mean Acute Physiology And Chronic Health Evaluation II score was higher in patients colonized with E. faecium than E. faecalis (26.3 vs 18.8), but statistical significance was not obtained. The 14-day mortality rate in the E. ...
... Three patients presented with disseminated intravascular coagulation. The mean Acute Physiology And Chronic Health Evaluation II score was higher in patients colonized with E. faecium than E. faecalis (26.3 vs 18.8), but statistical significance was not obtained. The 14-day mortality rate in the E. ...
weighing up the risks: hazards of anaemia
... 90% (deduced from the oxy-haemoglobin dissociation curve).(20) Although during acute normovoleamic anaemia there is an expansion of the plasma compartment containing dissolved oxygen. So by hyperoxic ventilation (FiO2 = 60%) it is possible to saturate this compartment fully causing an increased grad ...
... 90% (deduced from the oxy-haemoglobin dissociation curve).(20) Although during acute normovoleamic anaemia there is an expansion of the plasma compartment containing dissolved oxygen. So by hyperoxic ventilation (FiO2 = 60%) it is possible to saturate this compartment fully causing an increased grad ...
Extensive Mucocutaneous Histiocytic Sarcoma raised from an Acute
... by the accumulation of macrophages, dendritic cells or monocytederived cells in various tissues and organs [6]. It accounts for less than 1% of all cases of haemato-lymphoid neoplasms and it has predominance in children and young adult males [7]. They are described as an entity that may arise post-t ...
... by the accumulation of macrophages, dendritic cells or monocytederived cells in various tissues and organs [6]. It accounts for less than 1% of all cases of haemato-lymphoid neoplasms and it has predominance in children and young adult males [7]. They are described as an entity that may arise post-t ...
The effect of low versus high tidal volume ventilation on
... Main Results: A significant increase in IL-6, IL-8, and urine desmosine levels was noted over time compared with baseline (P b 0.01). However, no significant difference in the levels of markers was seen between the groups at any time point when controlling for demographics, ASA physical status, body ...
... Main Results: A significant increase in IL-6, IL-8, and urine desmosine levels was noted over time compared with baseline (P b 0.01). However, no significant difference in the levels of markers was seen between the groups at any time point when controlling for demographics, ASA physical status, body ...
Comprehensive Reference Ranges for Hematology and Clinical
... laboratory test results and provision of quality services in the Health care delivery. The aim of this study was to determine ...
... laboratory test results and provision of quality services in the Health care delivery. The aim of this study was to determine ...
Urinalysis and Kidney Disease
... There are five stages of kidney disease. They are shown in the table below. Your healthcare provider determines your stage of kidney disease based on the presence of kidney damage and your glomerular filtration rate (GFR), which is a measure of your kidney function. Your treatment is based on your s ...
... There are five stages of kidney disease. They are shown in the table below. Your healthcare provider determines your stage of kidney disease based on the presence of kidney damage and your glomerular filtration rate (GFR), which is a measure of your kidney function. Your treatment is based on your s ...
Purification and renaturation of recombinant proteins produced in
... in some instances by as much as 25%. The r-proteins so produced are frequently in the form of insoluble aggregates (2, 3), so-called inclusion bodies. The inclusion bodies contain reduced and denatured proteins lacking biological activity (4, 5). Their sizes and densities are distinct from most of t ...
... in some instances by as much as 25%. The r-proteins so produced are frequently in the form of insoluble aggregates (2, 3), so-called inclusion bodies. The inclusion bodies contain reduced and denatured proteins lacking biological activity (4, 5). Their sizes and densities are distinct from most of t ...
Piezo1 links mechanical forces to red blood cell volume | eLife
... However, not much is known about the roles of these ‘Piezo’ ion channels. Red blood cells experience significant forces when they pass through narrow blood vessels. In a disease called xerocytosis, the red blood cells become severely dehydrated and shrink. In 2013, researchers discovered that patien ...
... However, not much is known about the roles of these ‘Piezo’ ion channels. Red blood cells experience significant forces when they pass through narrow blood vessels. In a disease called xerocytosis, the red blood cells become severely dehydrated and shrink. In 2013, researchers discovered that patien ...
Some Important Milestones: Hepatitis C, 1974–95
... would reduce the incidence of post-transfusion non-A, non-B hepatitis by as much as 50 per cent. The Lancet) By 1987, the problem of hepatitis C was well known. International strategies to reduce the incidence of post transfusion hepatitis caused by NANB in donated blood had been in place internatio ...
... would reduce the incidence of post-transfusion non-A, non-B hepatitis by as much as 50 per cent. The Lancet) By 1987, the problem of hepatitis C was well known. International strategies to reduce the incidence of post transfusion hepatitis caused by NANB in donated blood had been in place internatio ...
Long-Term Follow-Up of Patients With Hairy Cell
... of the percent infiltration by hairy cell leukemia of the bone marrow only if these criteria were met. There were no age restrictions. Patients were excluded if they had received treatment within 4 weeks of cladribine therapy, if they had an active infection, or if they had abnormal renal or hepatic ...
... of the percent infiltration by hairy cell leukemia of the bone marrow only if these criteria were met. There were no age restrictions. Patients were excluded if they had received treatment within 4 weeks of cladribine therapy, if they had an active infection, or if they had abnormal renal or hepatic ...
MTS Gel Card Package Insert
... non-upright position. Reactions stored in the refrigerator (2–8 oC) and effectively protected from evaporation were able to be interpreted for more than 14 days. Gel cards should not continue to be interpreted after the first sign of drying, or if hemolysis is observed. The age and condition of red ...
... non-upright position. Reactions stored in the refrigerator (2–8 oC) and effectively protected from evaporation were able to be interpreted for more than 14 days. Gel cards should not continue to be interpreted after the first sign of drying, or if hemolysis is observed. The age and condition of red ...
SICKLE CELL DISEASE - Virginia Osteopathic Medical Association
... which the individual is homozygous for the mutation that causes HbS. Normal hemoglobin is called hemoglobin A, but people with sickle cell anemia have only hemoglobin S, which in the homozygous form, turns normal, round red blood cells into abnormally curved (sickle) shapes. Sickling decreases the c ...
... which the individual is homozygous for the mutation that causes HbS. Normal hemoglobin is called hemoglobin A, but people with sickle cell anemia have only hemoglobin S, which in the homozygous form, turns normal, round red blood cells into abnormally curved (sickle) shapes. Sickling decreases the c ...
Clinical Characteristics of Patients with Acute Coronary Syndrome at
... this may be prognostic for a worse outcome. Our data confirmed previous results18 that, in patients with sleep-disordered breathing, glomerular filtration rate is reduced; thus, even mild renal disease, as assessed by the estimated glomerular filtration rate, should be considered as a major risk fac ...
... this may be prognostic for a worse outcome. Our data confirmed previous results18 that, in patients with sleep-disordered breathing, glomerular filtration rate is reduced; thus, even mild renal disease, as assessed by the estimated glomerular filtration rate, should be considered as a major risk fac ...
Diabetes and Chronic Liver Disease: Etiology
... increase of A1C unrelated to glucose levels or GA concentration.46 Similar findings were recently reported in pregnant women with diabetes.47 Reports in children with type 1 diabetes have also found a decrease in A1C with iron repletion independent of blood glucose control.44 In contrast, some studi ...
... increase of A1C unrelated to glucose levels or GA concentration.46 Similar findings were recently reported in pregnant women with diabetes.47 Reports in children with type 1 diabetes have also found a decrease in A1C with iron repletion independent of blood glucose control.44 In contrast, some studi ...
ROX Coupler for Treatment-resistant Hypertension
... persistent, elevated blood pressure that remains above blood pressure goals despite the use of three antihypertensive agents. Ideally, one of the antihypertensive agents should be a diuretic (a drug that promotes urine production). A patient whose blood pressure is controlled using four or more medi ...
... persistent, elevated blood pressure that remains above blood pressure goals despite the use of three antihypertensive agents. Ideally, one of the antihypertensive agents should be a diuretic (a drug that promotes urine production). A patient whose blood pressure is controlled using four or more medi ...
Fulminant Neuroleptic Malignant Syndrome Induced by Low Doses
... Neuroleptic malignant syndrome (NMS), a rare but life-threatening idiosyncratic adverse reaction to antipsychotic medication. NMS is commonly seen with typical antipsychotics, that also reported with atypical antipsychotic drugs. A 81-year-old man was presented to emergency department of our hospita ...
... Neuroleptic malignant syndrome (NMS), a rare but life-threatening idiosyncratic adverse reaction to antipsychotic medication. NMS is commonly seen with typical antipsychotics, that also reported with atypical antipsychotic drugs. A 81-year-old man was presented to emergency department of our hospita ...
An association of candidate gene haplotypes and
... Baka (HPA-3a) alloantigen determinant (frequency 0.616), whereas Ser843 represents the Bakb (HPA-3b) epitope. An initial indication that HPA-3 is related to mortality after stroke17 was followed by larger studies that did not find a risk association in either stroke18 or coronary artery disease.19 H ...
... Baka (HPA-3a) alloantigen determinant (frequency 0.616), whereas Ser843 represents the Bakb (HPA-3b) epitope. An initial indication that HPA-3 is related to mortality after stroke17 was followed by larger studies that did not find a risk association in either stroke18 or coronary artery disease.19 H ...
Serum Uric Acid Levels and Incident Chronic
... the general population and other nondiabetic high-risk patient populations. However, epidemiologic data are limited about the relationship between hyperuricemia and adverse renal outcomes in patients with type 1 (21,22) or type 2 (23) diabetes. In a post hoc analysis of 1,342 patients with type 2 di ...
... the general population and other nondiabetic high-risk patient populations. However, epidemiologic data are limited about the relationship between hyperuricemia and adverse renal outcomes in patients with type 1 (21,22) or type 2 (23) diabetes. In a post hoc analysis of 1,342 patients with type 2 di ...
Hematological changes like anaemia are the most common
... and P. malariae. Among them P. vivax and P. falciparum are the most common infectious agents in India. The most serious and sometimes fatal type of malaria is caused by Plasmodium falciparum.2 Malaria can be transmitted mainly through mosquito bites, and by blood transfusion, through needles and syr ...
... and P. malariae. Among them P. vivax and P. falciparum are the most common infectious agents in India. The most serious and sometimes fatal type of malaria is caused by Plasmodium falciparum.2 Malaria can be transmitted mainly through mosquito bites, and by blood transfusion, through needles and syr ...
Program and abstract book
... Anemia on the ICU, how to fight an ancient foe Lucas van Eijk Radboud University Medical Center, Nijmegen, The Netherlands Anemia is a frequent complication of critical illness and is associated with poor outcomes, particularly in patients with ischemic heart disease. At the same time studies have a ...
... Anemia on the ICU, how to fight an ancient foe Lucas van Eijk Radboud University Medical Center, Nijmegen, The Netherlands Anemia is a frequent complication of critical illness and is associated with poor outcomes, particularly in patients with ischemic heart disease. At the same time studies have a ...
A Case of Hemophilia A Presenting in a Neonate and a Review of
... Hemophilia A is an X-linked hereditary condition caused by decreased factor VIII activity, which predominately occurs in males.1 Severe hemophilia occurs when circulating levels of a factor are less than 1% of normal activity in the blood and is typically diagnosed in the first 2 years of life.2 Ear ...
... Hemophilia A is an X-linked hereditary condition caused by decreased factor VIII activity, which predominately occurs in males.1 Severe hemophilia occurs when circulating levels of a factor are less than 1% of normal activity in the blood and is typically diagnosed in the first 2 years of life.2 Ear ...
Clinical significance of serum TNF-a and IL
... overweight adolescents and children with MetS had significantly greater serum IL-6 levels than their counterparts without MetS (22). In contrast, some studies have shown that IL-6 serum levels are not associated with MetS, which disagrees with our results (23, 24). Aldaham et al. showed that IL-6 se ...
... overweight adolescents and children with MetS had significantly greater serum IL-6 levels than their counterparts without MetS (22). In contrast, some studies have shown that IL-6 serum levels are not associated with MetS, which disagrees with our results (23, 24). Aldaham et al. showed that IL-6 se ...
Sideroblastic anaemias
... pseudouridylation of mitochondrial tRNAs was proposed as the pathophysiological mechanism leading to SA (32). 2.3 SA attributable to mutations in mitochondrial DNA 2.3.1 Pearson syndrome Pearson syndrome is characterised by severe, transfusion-dependent SA in childhood, exocrine pancreatic insuffici ...
... pseudouridylation of mitochondrial tRNAs was proposed as the pathophysiological mechanism leading to SA (32). 2.3 SA attributable to mutations in mitochondrial DNA 2.3.1 Pearson syndrome Pearson syndrome is characterised by severe, transfusion-dependent SA in childhood, exocrine pancreatic insuffici ...
Dengue presenting as Acute Liver Failure – A case report
... done to rule out autoimmune hepatitis but it came out to be negative. Patient developed super added sepsis during hospital stay as there was evidence of raised total leukocyte counts associated with neutrophilia. Acute liver failure manifested in the form of raised liver enzymes, coagulopathy, and e ...
... done to rule out autoimmune hepatitis but it came out to be negative. Patient developed super added sepsis during hospital stay as there was evidence of raised total leukocyte counts associated with neutrophilia. Acute liver failure manifested in the form of raised liver enzymes, coagulopathy, and e ...
Each team will determine the blood type of: the victim, the four
... If very high numbers of antibody molecules bind to high concentration of antigen, “clumping” (also called agglutination) may occur as the mixture becomes insoluble and large. “Clumping” in the blood plasma is not a beneficial response as it can lead to kidney damage, kidney failure, and even death. ...
... If very high numbers of antibody molecules bind to high concentration of antigen, “clumping” (also called agglutination) may occur as the mixture becomes insoluble and large. “Clumping” in the blood plasma is not a beneficial response as it can lead to kidney damage, kidney failure, and even death. ...
Hemolytic-uremic syndrome
Hemolytic-uremic syndrome (or haemolytic-uraemic syndrome), abbreviated HUS, is a disease characterized by hemolytic anemia (anemia caused by destruction of red blood cells), acute kidney failure (uremia), and a low platelet count (thrombocytopenia). It predominantly, but not exclusively, affects children. Most cases are preceded by an episode of infectious, sometimes bloody, diarrhea acquired as a foodborne illness or from a contaminated water supply and caused by E. coli O157:H7, although Shigella, Campylobacter and a variety of viruses have also been implicated. It is now the most common cause of acquired acute renal failure in childhood. It is a medical emergency and carries a 5–10% mortality; of the remainder, the majority recover without major consequences but a small proportion develop chronic kidney disease and become reliant on renal replacement therapy.The primary target appears to be the vascular endothelial cell. This may explain the pathogenesis of HUS, in which a characteristic renal lesion is capillary microangiopathy.HUS was first defined as a syndrome in 1955. The more common form of the disease, Shiga-like toxin-producing E. coli HUS (STEC-HUS), is triggered by the infectious agent E. coli O157:H7. Certain Shiga toxin secreting strains of Shigella dysenteriae can also cause HUS. Approximately 5% of cases are classified as pneumococcal HUS, which results from infection by Streptococcus pneumoniae, the agent that causes traditional lobar pneumonia. There is also a rare, chronic, and severe form known as atypical hemolytic uremic syndrome (aHUS), which is caused by genetic defects resulting in chronic, uncontrolled complement activation. Both STEC-HUS and aHUS cause endothelial damage, leukocyte activation, platelet activation, and widespread inflammation and multiple thromboses in the small blood vessels, a condition known as systemic thrombotic microangiopathy (TMA), which leads to thrombotic events as well as organ damage/failure and death.