• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Supplementary Method Legends
Supplementary Method Legends

... Tissue sections were imaged with a Keyence BZ-9000 All-in-one Fluorescence Microscope (Biorevo) at a 20x magnification. For fluorescence quantification, 3 fields per mouse tissue section were chosen at random by DAPI nuclear staining; total fluorescence area normalized to nuclear count per field was ...
campbell biology in focus
campbell biology in focus

... Which of the following is true of heterochromatin but not of euchromatin? A. It is accessible to enzymes needed for gene expression. B. It becomes less tightly compacted after cell division. C. It includes DNA primarily found in expressed genes. D. It appears more pale when observed microscopically ...
Chapter 2 - Test Bank 1
Chapter 2 - Test Bank 1

... 8. The 20 amino acids are strung together in different amounts and sequences to produce a very large number of proteins. This is the genetic code, common to all forms of life. B. Genes and Alleles 1. The text then focuses more narrowly on genes. These units specify production of an enzyme, or a kind ...


... Second, most of these differences occur in DNA that we assume to be neutral, between genes rather than in coding sequences. Therefore, unlike protein differences which are often deleterious or selective, DNA differences may be passed from generation to generation, apparently making little or no diff ...
Biology Pre-Learning Check
Biology Pre-Learning Check

...  Complete (Simple ) dominance  Incomplete dominance  Codominance  Dihybrid crosses  Sex-linked traits  Pedigrees The assessment for this unit will be a paper and pencil test over genetics and inheritance. It has multiple choice and diagrams. There will be some genetic problems for you to inter ...
Seven types of pleiotropy
Seven types of pleiotropy

... 1979; Finney et al., 1988). Again, when the locus was cloned it became clear that the nondisjunction alleles were all small deletions affecting not only unc-86 but also two adjacent transcription units, one of which is presumably required for normal meiosis (Finney et al., 1989). The multiple effect ...
Transcription PPT
Transcription PPT

... How do we move information from DNA to proteins? ...
Resources: http://sciencevideos
Resources: http://sciencevideos

... Hemoglobin is a protein composed of two pairs of globin molecules. During the process of development from conception to adulthood, human hemoglobin changes in composition. Adult hemoglobin consists of two alpha- and two beta-globin molecules. Two globin genes occur on chromosome 16: alpha- and zeta- ...
Genome Evolution, Chromosomal Mutations, Paralogy
Genome Evolution, Chromosomal Mutations, Paralogy

... [Bejerano Fall09/10] ...
Transformation of the bacterium E. coli using a gene for green
Transformation of the bacterium E. coli using a gene for green

... production of insulin. Some bacteria have been modified such that they are able to digest oil from accidental spills. Bacteria are single celled organisms that can easily pass information between one another and thus changes in genetic make-up are rapidly passed on to subsequent generations. Transfo ...
Mutations and Disorders worksheet-ANS
Mutations and Disorders worksheet-ANS

... occurs during meiosis I, all of the cells will be affected and if one of the cells is fertilized it will result in a zygote with too many or too few chromosomes. If nondisjunction occurs during meiosis II, half of the cells will be affected and half will be normal. ...
File
File

... and hybridising it to the gene chip. After scanning, the two data sets were compared. Genes showing increased or decreased expression, relative to the control, were highlighted and statistically analysed by Dr Marta Milo. Although 82 genes were found to have significant differences in expression, To ...
Learning Grid Cellular control
Learning Grid Cellular control

... How many amino acids are used for protein synthesis? The genetic code What is meant by a degenerate code? What else other than amino acids can a triplet code for? ...
Experimental Procedures for Grant Write-Up
Experimental Procedures for Grant Write-Up

... b. Background values: The background value provides a measure of the signal intensity resulting from autofluorescence of the array surface and nonspecific binding of target or stain molecules. The background values for all the arrays in one experiment should be within +25% of the overall average bac ...
New Title - Gravette School District
New Title - Gravette School District

... Eukaryotic Gene Regulation The general principles of gene regulation in prokaryotes also apply to eukaryotic cells, although there are some important differences. Operons are generally not found in eukaryotes. Most eukaryotic genes are controlled individually and have regulatory sequences that are m ...
The Molecular - MolGen | RuG
The Molecular - MolGen | RuG

... Phages have been widely used as tools by researchers ...
Diolistics: A Pun Within a Pun
Diolistics: A Pun Within a Pun

... First: bio + ballistics = biolistics (coined by Ed and Marlene Wolf, 1986) ...
Development of a New Method to Prioritise Gene Analysis in
Development of a New Method to Prioritise Gene Analysis in

... was not excluded in any of the analyses performed. • More genes tend to be excluded when more distantly related individuals such as first cousins or aunt/niece, nephew pairs are considered, rather than more closely related sibs • GLEAM can be used to determine the order in which genes are sequenced ...
Sordaria
Sordaria

... chromatid of a synapsed tetrad to be followed through the entire meiotic process, including the events of recombination and crossing over if they occur. Two major types of important information can be obtained in this way. The first (using ordered tetrad analysis) allows identification of which two ...
Chromosome Mutations
Chromosome Mutations

... nucleotide sequence of DNA  May occur in somatic cells (aren’t passed to offspring)  May occur in gametes (eggs & sperm) and be passed to offspring ...
SUMMARY NOTIFICATION INFORMATION FORMAT FOR THE RELEASE OF GENETICALLY MODIFIED HIGHER PLANTS
SUMMARY NOTIFICATION INFORMATION FORMAT FOR THE RELEASE OF GENETICALLY MODIFIED HIGHER PLANTS

... The cisgenic potato line contains the NB-LRR gene Rpi-vnt1.1 from S. venturii, which confers broad spectrum resistance to P. infestans. Many conventional potato varieties also contain NB-LRR-genes that have been introgressed from wild Solanum species. The NB-LRR class of genes are present in many cu ...
Gene discovery within the planctomycete division of the domain
Gene discovery within the planctomycete division of the domain

... comparison of individual clone nucleotide sequence translated in all reading frames against protein-sequence databases using the BLASTX algorithm (Tables 1,2). Only sequence matches with expected (e) values below E-4 (as determined by BLASTX) were considered to be significant [33] and are presented ...
A1982NA86800001
A1982NA86800001

... ography of 763 citations. Obviously, New Haven, CT 06510 not every person using E. co/i could afford to perform this synthesis for himself. It is the drawing, the bibliogOctober 27, 1981 raphy, and the table of gene functions that are most often used. Apparently, “The series of linkage maps of few p ...
Gene Section ETV6 (ETS variant gene 6 (TEL oncogene))
Gene Section ETV6 (ETS variant gene 6 (TEL oncogene))

Gene Section THBS1 (thrombospondin-1) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Gene Section THBS1 (thrombospondin-1) Atlas of Genetics and Cytogenetics in Oncology and Haematology

< 1 ... 752 753 754 755 756 757 758 759 760 ... 1288 >

Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report