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Guide to 2nd Drosophila discussion
Guide to 2nd Drosophila discussion

... chromosomes in interphase allows the “cis” acting regulatory sequences to act in trans on the promoter of the homolog. Thus, mutations in “cis” acting regulatory regions are thought to complemented by an allele with normal “cis” acting sequences but a defective coding sequence. While this interpreta ...
Evolution of Livestock Improvement
Evolution of Livestock Improvement

... Retroviruses are unique organisms in that they use RNA as their genome rather than DNA, therefore they code genetic information from RNA to DNA. When retroviruses infect a host organism a DNA sequence (provirus) complementary to their RNA is produced in the infected cells. This provirus inserts itse ...
Meiosis
Meiosis

... Mitosis – division of body cells (somatic cells) • End result - 2 cells identical to starting cell w/same number of chromosomes • Meiosis – production of sex cells (sperm & egg) (gametes) • End result – 4 cells with ½ the chromosome number as starting cell ...
7.1 Chromosomes and Phenotype KEY CONCEPT affect the expression of traits.
7.1 Chromosomes and Phenotype KEY CONCEPT affect the expression of traits.

Recombinant DNA Technology
Recombinant DNA Technology

... 2. Once a gene is sequenced, it can be used in recombinant DNA techniques. Sequencing is a technique used to determine the order of genetic information in DNA. For example the sequence of a gene might begin as C A T A T G. One of the first genes sequenced was the gene that codes for insulin, a hormo ...
PDF
PDF

... expression of the transcription factors Drifter, Runt, Homothorax and Brainspecific homeobox. The birth order of the medulla neurons correlates with the expression pattern of these factors, they report, and each neuronal type exhibits an extensive but defined pattern of migration that disrupts the c ...
Human immunodeficiency virus (HIV)
Human immunodeficiency virus (HIV)

... (Côt) – Côte d’Ivore (MIDDLE AFRICA) (Rus) – Northwest Russia (MIDDLE ASIA) ...
PDF
PDF

... expression of the transcription factors Drifter, Runt, Homothorax and Brainspecific homeobox. The birth order of the medulla neurons correlates with the expression pattern of these factors, they report, and each neuronal type exhibits an extensive but defined pattern of migration that disrupts the c ...
What Do Genes Look Like? - Effingham County Schools
What Do Genes Look Like? - Effingham County Schools

... • Genetically engineering chickens so they have no feathers – why? • Genetically engineering mice so they have no fur – why? • Genetically engineering salmon (fish) so they grow much faster than normal salmon – why? http://www.exn.ca/Stories/2 000/04/11/61.asp • Glowing mice ...
Document
Document

... • traits are the result of interactions of the genes of both parents. • 1. Inherited characteristics are controlled by factors called genes • 2. One gene masks the effects of another. Principle of dominance • 3. A pair of factors or genes, segregate during the formation of gametes – law of Segregati ...
PDF
PDF

... expression of the transcription factors Drifter, Runt, Homothorax and Brainspecific homeobox. The birth order of the medulla neurons correlates with the expression pattern of these factors, they report, and each neuronal type exhibits an extensive but defined pattern of migration that disrupts the c ...
plasmid vector
plasmid vector

... 7. The relaxosome, consisting of Y, M, l and hostencoded lHF bound to the nicked DNA in oriT is shown interacting with the coupling protein, D, which in turn interacts with B. 8. The 5’ end of the nicked strand is shown bound to a tyrosine (Y) in l, and the 3’ end is shown being associated with l in ...
cDNA Sequences of Three Kinds of /3
cDNA Sequences of Three Kinds of /3

... R2242) were determined. Southern hybridization indicated that these /3-tubulins consist of one gene family. Using RFLP mapping, these three /3-tubulin cDNAs were mapped to different chromosomes indicating at least three loci for the /3-tubulin gene. The deduced amino acid sequences of these cDNAs sh ...
Leukaemia Section t(12;22)(p13;q11-12) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(12;22)(p13;q11-12) Atlas of Genetics and Cytogenetics in Oncology and Haematology

Gene Section IGK (Immunoglobulin Kappa) Atlas of Genetics and Cytogenetics
Gene Section IGK (Immunoglobulin Kappa) Atlas of Genetics and Cytogenetics

Answers to Mastering Concepts Questions
Answers to Mastering Concepts Questions

... 13. Parkinson disease causes rigidity, tremors, and other motor symptoms. Only 2% of cases are inherited, and these tend to have an early onset of symptoms. Some inherited cases result from mutations in a gene that encodes the protein parkin, which has 12 exons. Indicate whether each of the followi ...
Coding for Amino Acids and Proteins
Coding for Amino Acids and Proteins

... (Emphasize that the mutation changed all the amino acids in the sequence.) 4. Provide each group of students with a Snickers Bar, a 3Muskateers bar, or a Reese cup. 5. Have each group figure out their base sequence by simply matching, in order, their candy bar’s simple ingredients. 6. Use the base s ...
ch 10 Human GeneticsTest Qustions Study Guide
ch 10 Human GeneticsTest Qustions Study Guide

... b. All of the symbols are unshaded c. All of the symbols are half-shaded d. All of the symbols are shaded 10. Some gametes may have an extra copy of some genes if nondisjunction occurs during meiosis 11. Is PKU caused by a dominant allele? PKU? Huntington’s? 12. Which blood genotype also has the sam ...
Number 4 - Laboratory Animal Boards Study Group
Number 4 - Laboratory Animal Boards Study Group

... linkage cross (high resolution cross). To identify the mutated gene, one then either sequences candidate genes in DNA from mutant mice or performs expression analysis to look for reduced or lack of expression. Because each new spontaneous or chemically induced mutation is a unique event, efficient ...
population
population

... • Two processes, mutation and sexual recombination, produce the variation in gene pools that contributes to differences among individuals ...
Station Lab Part 2
Station Lab Part 2

... hormone that the body needs to get glucose from the bloodstream into the cells of the body. Type 1 and Type 2 diabetes have different causes. Yet two factors are important in both. You inherit a predisposition to the disease then something in your environment triggers it. Genes alone are not enough. ...
Genetic Nomenclature
Genetic Nomenclature

... Aa is equivalent to A/a to describe a genotype. “/” is used to show that “A” allele and “a” allele are associated with homologous chromosomes “A” is on one homologue, “a” is on the other ...
Genes are…
Genes are…

... What if an offspring inherits one recessive gene from their mother and one recessive gene from their father? Example: bb for blond hair We call that being homozygous recessive. Two genes the same; use lower case. ...
Genetic Nomenclature
Genetic Nomenclature

... Aa is equivalent to A/a to describe a genotype. “/” is used to show that “A” allele and “a” allele are associated with homologous chromosomes “A” is on one homologue, “a” is on the other ...
how to read a pedigree - Doral Academy Preparatory
how to read a pedigree - Doral Academy Preparatory

... By Cutting DNA from one organism and inserting fragments into a host Recombinant DNA Alters the allele frequency of a population by artificial ...
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Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
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