• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
q 2 - cloudfront.net
q 2 - cloudfront.net

... • The Hardy-Weinberg equation is useful for predicting the percent of a human population that may be heterozygous carriers of recessive alleles for certain genetic diseases. Phenylketonuria (PKU) is a human metabolic disorder that results in mental retardation if it is untreated in infancy. In the U ...
Microbial Genetics - University of Montana
Microbial Genetics - University of Montana

... T-even and T-odd phage The T-even phages, T2, T4 and T6, are all related serologically and all have large genomes; T4 has a genome 168,895 bp in length The T-odd phages fall into three serological groups: T3 and T7 are related to each other but not to T1 or to T5, which are unrelated. The T7 genome ...
chapter_07a
chapter_07a

... Liver enzymes are required to detect mutagens that are converted to carcinogenic forms by the liver (e.g., procarcinogens). ...
Overview - University of Missouri
Overview - University of Missouri

... Recombination and Mapping  Assume that the frequency of crossing-over is equal along the chromosome.  Two genes that are very close to one another will have a lower likelihood of having a cross-over between them than two genes that are very far apart. ...
Biotechnology and Recombinant DNA
Biotechnology and Recombinant DNA

...  Uses probes to detect DNA sequences in restriction fragments separated using gel ...
Gene Section EXT1 (exostoses (multiple) 1) Atlas of Genetics and Cytogenetics
Gene Section EXT1 (exostoses (multiple) 1) Atlas of Genetics and Cytogenetics

Are Humans Still Evolving? - AHRC Centre for the Evolution of
Are Humans Still Evolving? - AHRC Centre for the Evolution of

... Whatever lies in our evolutionary future, (PNAS) that natural selection probably traits such as modern human skull shape may scientists agree that the modern human drove the evolution of facial form up to the be due to random drift, some changes in body form is largely the result of evolution- birth ...
Practice Exam II-1 _ _1. The arrows in the pathway represent? a
Practice Exam II-1 _ _1. The arrows in the pathway represent? a

... ___11. If Iodothyroxin production is regulated by feedback inhibition, the regulated step is expected to involve "arrow"? a. #5 b. #8 c. #9 d. #10 e. several ___ 12. The compound which would accumulate in a mutant missing #12 is: a. Dietary protein b. Tyrosine c. p-HPA d. DHPA ...
Of Flies and Fishes - School of Natural Sciences
Of Flies and Fishes - School of Natural Sciences

Slide 1
Slide 1

... The Human Genome Project:  This is the sequencing of all of the DNA of ...
Biology 40S – Final Exam Review (2013
Biology 40S – Final Exam Review (2013

... o Animals are heterotrophs, through and through. They are multicellular (not like those protozoans, being all “single-celled” and obsessively individual. What hipsters!), eukaryotic, and often have systems of tissues and organs. Sexual reproduction is common, as is motility (though some sessile anim ...
genes and chromosomes chromosomes in sex cells - Florida 4-H
genes and chromosomes chromosomes in sex cells - Florida 4-H

... stallion. Both would be black. But their genotypes are different. The foal is Bb and the stallion is BB. What then would happen if a black stallion that had a Bb genotype were bred to a red (bb) mare? Two possible kinds of sperm would be produced by the Bb stallion. Half of the sperm would have the ...
Supplementary Information (doc 6692K)
Supplementary Information (doc 6692K)

... by immunohistochemical analysis of kidney sections (C) or immunofluorescence using cells purified from kidney metastases (D). Supplementary Figure 5. Gene expression profile analysis and qRT-PCR validation of the microarray data. (A) Unsupervised hierarchical clustering of Mec-1/CD38WT, /CD38M or /G ...
CR75th Anniversary Commentary
CR75th Anniversary Commentary

... that "few proteins have had such a strong impact on a field as the lac repressor has had in Molecular Biology" (2). It is hard to imagine, looking back, the degree to which the work of Jacob and Monod would become a knowledge base to build upon in elucidating the vast series of mechanisms used by cel ...
File
File

... 4.DNA polymerase has a proofreading function that enables it to detect (errors / enzymes) and correct them. 5.DNA replication occurs (before / after) cell division. 6.Where is DNA located inside the cell? So, where in the cell does DNA replication occur? 7.If a strand of DNA has the sequence T A G G ...
BLOOM HELICASE (and BLOOM SYNDROME)
BLOOM HELICASE (and BLOOM SYNDROME)

... BLM to pair homologous sequences and exchange DNA strands to form recombination intermediates  BLM is then needed to remove these intermediates in order to prevent excessive recombination ...
are we still evolving?
are we still evolving?

... evolutionary makeover from Stone Age times to the present is nothing short of blasphemous. Yet a team of researchers has done just that. They find an abundance of recent adaptive mutations etched in the human genome; even more shocking, these mutations seem ...
Supplementary Material Deep sequencing of the human
Supplementary Material Deep sequencing of the human

... Supplementary Figure S2. The anti-OR antibodies specifically detect recombinantly expressed ORs in Hana3A cells. Co-immunostaining of Hana3A cells transiently transfected with the respective rhotagged OR plasmid. Detection of the recombinant rho-OR5P3 (A) or rho-OR10AD1-protein (B) was performed us ...
Unique Human Subjects Concerns for j Genetic Research
Unique Human Subjects Concerns for j Genetic Research

... Genetic Information Non-discrimination Act of 2008 (plus prior HIPAA) Genetic information is defined as: Genetic tests on individual (including those done for research): analysis of DNA, RNA, chromosomes, proteins or metabolites to detect genotypes, mutations, or chromosomal changes Genetic tests o ...
6-6 Study Guide
6-6 Study Guide

... Refer to your cell sketch in the last box on the previous page. Also refer to Figure 2.3 if necessary. 1. In the first box below, show what your cell would look like at the end of meiosis I. Remember, the result will be two cells that have one duplicated chromosome from each homologous pair. 2. In t ...
Hutchinson Gilford Progeria Syndrome: A
Hutchinson Gilford Progeria Syndrome: A

... potentiality for its use in gene therapy. In fact, it permits to manipulate the site of pathogenic mutations using transient viral vectors such as the adenoviral-derived vectors or other non-integrating vectors. The great advantage is that even if the vector cannot integrate within the host, the con ...
H_Pylori_MicroArray_Data_Analysis
H_Pylori_MicroArray_Data_Analysis

... • Under the control of the RpoN there is an increase in transcription of genes ...
Cell Cycle DNA Structure and Replication Student PPT Nts
Cell Cycle DNA Structure and Replication Student PPT Nts

... • ______________________: when a chunk of DNA (usually large) is removed from 1 chromosome and attached to another ...
Document
Document

... Double Crossovers • More than one crossover event can occur in a single tetrad between non-sister chromatids, – if recombination occurs between genes A and B 30% of the time, • (p = 0.3), • then the probability of the event occurring twice is 0.3 x 0.3 = 0.09, or nearly 10 map units. ...
mutations
mutations

... replication DNA replication is very accurate The enzyme DNA polymerase “proofreads” the copied DNA & repairs most mutations Mutations can be harmful, beneficial or have no effect at all ...
< 1 ... 715 716 717 718 719 720 721 722 723 ... 1288 >

Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report