• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Drosophila
Drosophila

... Expansion of tandem gene clusters ...
4. Chromosomes and Inheritance
4. Chromosomes and Inheritance

DNA - Fort Bend ISD
DNA - Fort Bend ISD

... Each strand (side) of DNA serves as a template for a new strand of DNA 2. Steps of replication: a) Enzymes unzip DNA breaking hydrogen bonds between bases. ...
Chapter 14
Chapter 14

... blood. Type A blood has type B antibodies. If type B blood is put into their bodies, their immune system reacts as if it were a foreign invader, the antibodies clump the blood - can cause death. •Type AB blood has no antibodies, any blood can be donated to them - they are called the "universal accep ...
Genetics Objectives/keywords
Genetics Objectives/keywords

... 3. How can we use Punnett squares to predict genetic outcomes? 4. How can we use Mendel’s laws and Punnett squares to make assumptions of our own genotypes and phenotypes? PERFORMANCE OBJECTIVES: Students will be able to:  Describe the steps involved in Mendel’s experiments on garden peas.  Define ...
coxL - Université du Québec
coxL - Université du Québec

... explanatory variables) and coxL gene sequences (Hellinger-transformed OTU frequency data) were integrated into redundancy analysis (RDA) in order to identify clone sequences linked to elevated CO uptake activity and the environmental factors influencing their distribution. The most parsimonious mode ...
Identifying Factors that Control Mechanoreceptor Neuron
Identifying Factors that Control Mechanoreceptor Neuron

... However, the genes that restrict FLP fate in other cells remain unknown. We hypothesize that another gene or network of genes is restricting sto-5 expression to FLP neurons and is not allowing mec gene expression in the FLPs (which inhibits TRN fate). One morphological mutant was identified through ...
Supplementary Methods and Results Sequencing bias due to
Supplementary Methods and Results Sequencing bias due to

... Several investigators (notably Oshlack and Wakefield, 2009) have pointed out that a long transcript will tend to have higher aggregate read counts than a short transcript, even if the two have equal expression, as the long transcript has more opportunities for sequences from fragmented reads to appe ...
The Human Genome.
The Human Genome.

... available to all – like calendar  or Einstein theory of Relativity  or Double Helix of DNA ...
Examples of genetic disorders
Examples of genetic disorders

... the mutation of tumor suppressor gene (FAP) → risk of malignancy in adulthood → progression toward an adenocarcinoma: 1) deletion of the second normal FAP gene, 2) hypomethylation of DNA, 3) activation of K-ras oncogene, 4) deletion of DCC (deleted in colorectal carcinoma) gene, 5) deletion of P53 g ...
Gene7-21
Gene7-21

... 6. HLH (helix-loop-helix) proteins have amphipathic helices that are responsible for dimerization, adjacent to basic regions that bind to DNA. 7. Many transcription factors function as dimers, and it is common for there to be multiple members of a family that form homodimers and heterodimers. 8. The ...
genetics, health and disease
genetics, health and disease

... Our bodies are built from millions of cells, each of which contains the information for making and maintaining a human body. The full set of information, our genome, consists of around 25,000 individual genes that organise how our bodies grow and develop from a single fertilised egg. Genetics is the ...
Variation in Natural Populations
Variation in Natural Populations

... Alleles in an inversion are “locked together” and may be selected together as one ...
cinnabar - UWL faculty websites
cinnabar - UWL faculty websites

... more flanking lethal complementation groups (Alexandrov, 1984; Alexandrov & Alexandrov, 1991; Lindsley & Zimm, 1992; Wustmann et al., 1989). Radiolabelled DNA prepared from the )tG3 clone was found to hybridize to Df( 2R )CA5 31CyO and Df( 2R )cn-h31CyO DNA with approximately half the intensity of t ...
Leukaemia Section t(5;14)(q33;q24) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(5;14)(q33;q24) Atlas of Genetics and Cytogenetics in Oncology and Haematology

Genetic alterations and DNA repair in human carcinogenesis
Genetic alterations and DNA repair in human carcinogenesis

... “birth rate” of cells [7]. The p53 protein is important in cellular responses to stress, controlling DNA repair, cell cycle checkpoints, and apoptosis [9]. Perhaps, the most important of these pathways for cancer development is apoptosis; loss of p53 function can lead to decreased apoptosis, i.e., a ...
Deteksi Mutasi Gen Gyrase A Porphyromonas Gingivalis Resisten
Deteksi Mutasi Gen Gyrase A Porphyromonas Gingivalis Resisten

... ABSTRACT One of resistance mechanisms to ciprofloxacin shown by bacterium Porphyromonas gingivalis isolated from periodontitis patients is mutations of genes through changes in DNA topoisomerase. Ciprofloxacin is an effective antimicrobial for Gram-negative bacteria effectively used for clinical inf ...
AGRA: analysis of gene ranking algorithms
AGRA: analysis of gene ranking algorithms

... The use of microarray chips in gene expression analysis requires an enormous amount of data to be analysed and often, while at the same time, selecting the most informative genes from different gene sets. One of the possible ways to rank the genes is to use a feature selection (FS) method. FS is a m ...
CLEFT CHIN (PPT picture #8)
CLEFT CHIN (PPT picture #8)

... This is a super-weird result, because it tells us that freckles are a dominant trait, being expressed even when there’s only one copy of the gene in question, but red hair itself is recessive-even though they’re both caused by the same gene. Genetics is really cool and complicated, guys. BLUE EYES ...
double core - MG University
double core - MG University

Chapter 7 Human Inheritance
Chapter 7 Human Inheritance

... Unable to produce melanin – the pigment responsible for human skin color Have no color in hair or skin Sensitive to light Most common fatal genetic disease. Recessive allele on chromosome 7 Makes a defective cell membrane protein that interferes with the movement of chloride ions into and out of the ...
Genes
Genes

... Some traits are coded for by one gene which codes for one protein causing a trait.  i.e. freckles, earlobe attachment, etc ...
Chapter 15 Study Questions
Chapter 15 Study Questions

Glucocorticoid-remediable aldosteronism
Glucocorticoid-remediable aldosteronism

... in GRA, they have been found in rodents to have only weak mineralocorticoid activity [8]. However, it is possible that these hybrid compounds possesssignificant mineralocorticoid activity in humans. The molecular basis of GRA was discovered by applying a candidategene approachin a pedigree where aff ...
Heredity Basics Powerpoint
Heredity Basics Powerpoint

... the offspring. The Zygote (fertilized egg) would have at two least genes for each characteristic (one from mom and one from dad). The two genes that govern the same characteristic are known as alleles. A punnett square is used to visualize all possible combinations of alleles from parents.  PP = al ...
< 1 ... 648 649 650 651 652 653 654 655 656 ... 1288 >

Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report