• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Chapter 6 – Microbial Growth
Chapter 6 – Microbial Growth

... a. Transposase gene to facilitate recombination. Can cut and paste DNA strands. b. Inverted repeats – sequences that target new location and also is recognized by transposase. Chapter 8 Problems: Review 1, 2, 4, 7-9. MC 1, 2, 4-10. CT 1, 3. CA 2, 3. ...
A Novel Chimeric Low-Molecular-Weight Glutenin
A Novel Chimeric Low-Molecular-Weight Glutenin

... possessed characteristics of both LMW-i (1–43 residues) and LMW-m (44–298 residues) type genes. Five cloned LMW-GS genes were expressed in E. coli by two kinds of expression vectors (pGEX-4T-2 and pET-30a) to confirm their authenticity. The nucleotide sequences coding for mature proteins and complet ...
Division 4.qxd
Division 4.qxd

... eymour Benzer's work changed our notion of the concept of the gene, by demonstrating that the gene had a fine structure consisting of a linear array of subelements. At the time Benzer began his classic work, the concept of the gene was different from what it is today. Genes were thought to be indivi ...
Snurfle Meiosis
Snurfle Meiosis

... 1. In the first activity at the end of Meiosis 1 you had 4 haploid cells that were genetically ______________. Draw the 4 haploid cells. USE COLOR WITH PURPOSE!! ...
Chapter 11 Transcription and RNA Processing
Chapter 11 Transcription and RNA Processing

... – Only one strand of DNA is used as a template. – RNA chains can be initiated de novo (no primer required). ...
Frequency of mutations in the early growth response 2 gene
Frequency of mutations in the early growth response 2 gene

... The fact that the CMT, CH, and DSS phenotypes are associated with mutations of the same gene has previously been observed for MPZ and PMP22. Altered expression of a dosage sensitive gene in the peripheral nervous system can modify myelin structure and could potentially cause CH, in much the same way ...
a database designed for the polymorphisms of the human ccr2 gene
a database designed for the polymorphisms of the human ccr2 gene

... polymorphic markers (predominantly SNPs) in the CCR2 gene and its neighboring DNA regions, their population frequencies and also about the trait and diseases associated with these polymorphisms. The database consists of 4 interrelated tables. Table “GENE” contains the general information about the g ...
11 Chapter 7 Genetic Disorders
11 Chapter 7 Genetic Disorders

... environmental factors. Failure of closure of developing neural tube leads to a number of related conditions collectively termed as neural tube defects. The precise etiology of such conditions is not known, but can involve a number of environmental and genetic factors. There are many families where o ...
Ditto Chapter 15 Chromosomes
Ditto Chapter 15 Chromosomes

... translocation in which one copy of chromosome 21 becomes attached to chromosome 14 during meiosis. How does this differ from "conventional" Down Syndrome. ...
Human Genetics
Human Genetics

... Look at the handout provided: ...
Genetics Notes
Genetics Notes

... appear till later in life. • Ex. Muscular dystrophy has different onset ages, even for related individuals. • Huntington's disease, a dominant condition, does not usually appear till after the age of 40. ...
Epilepsy genetics update 080916
Epilepsy genetics update 080916

... • 69/335 Nottingham arrayCGH are above common CNVs ...
Coat Color Mutations, Animals
Coat Color Mutations, Animals

... During embyronic development, pigment cell precursors, melanoblasts, differentiate from a specialized region of the neural tube, the neural crest, which also gives rise to the peripheral nervous system, connective tissue of the head and neck, and a portion of the adrenal gland. The melanoblasts prol ...
Chapter 1: Characteristics of Living Things
Chapter 1: Characteristics of Living Things

... and intervals between data points have no meaning (points) d. Determining interval values for axis: i. First, find the difference between the smallest and largest values ii. Then divide by 5 (usually) iii. Round to nearest convenient counting number e. Summarizing Trends on a Line Graph: i. When the ...
Lecture 10 in molecular biology by Dr. Sawsan Saijd
Lecture 10 in molecular biology by Dr. Sawsan Saijd

...  1- The main function of DNA methylation in bacteria is to provide a mechanism, which protects the cell from the effect of foreign DNA introduction .Restriction endonucleases between endogenous differentiated and foreign DNA by its methylation pattern. Introduced DNA which is not protected by methy ...
Nomenclature I
Nomenclature I

... The first gene symbol allocated to an inherited clinical phenotype (monogenic mendelian inheritance) may be based on an acronym which has been established as a name for the disorder, while following the rules described previously, e.g., ACH for “achondroplasia.” It is usual for this symbol to change ...
DNA: The Molecule of Inheritance
DNA: The Molecule of Inheritance

... Early DNA Experiments: Griffith  Inject mice with live R bacteriamice live, no live R cells in blood  Inject mice with live S bacteriamice die, live S cells in blood  Inject mice with dead S bacteriamice live, no live S cells in blood  Inject mice with live R bacteria + dead S bacteriamice ...
Biology for Bioinformatics - NIU Department of Biological
Biology for Bioinformatics - NIU Department of Biological

... In prokaryotes, transcription and translation are essentially simultaneous: translation of the messenger RNA starts before transcription is completed. In eukaryotes, transcription occurs in the nucleus (where the DNA is), and translation occurs in the cytoplasm. This de-coupling of transcription and ...
Biology for Bioinformatics
Biology for Bioinformatics

... In prokaryotes, transcription and translation are essentially simultaneous: translation of the messenger RNA starts before transcription is completed. In eukaryotes, transcription occurs in the nucleus (where the DNA is), and translation occurs in the cytoplasm. This de-coupling of transcription and ...
unit v study guide for bio 156
unit v study guide for bio 156

... (D) During anaphase of Meiosis II, how many chromosomes are there per cell? 12 chromosomes. Each cell started meiosis II with 6 chromosomes, however, when the sister chromatids separate, the chromosomes number is temporarily doubled until the cell divides. (E) After Meiosis II is complete, and cytok ...
7.1 Chromosomes and Phenotype
7.1 Chromosomes and Phenotype

... KEY CONCEPT The chromosomes on which genes are located can affect the expression of traits. ...
Mendels Laws of Genetics
Mendels Laws of Genetics

... ▪One from MOM ▪One from DAD ...
Pedigree Analysis
Pedigree Analysis

... In 1996, Dolly the sheep became the first mammal to be cloned by transferring the nucleus from an adult body cell into an enucleated egg cell. To confirm that Dolly was truly a clone, researchers at the University of Hawaii used a similar process in 1998 and ultimately cloned 50 mice. In this activi ...
Population Genetics
Population Genetics

... frequencies to a population Tends to counteract natural selection and genetic drift ...
Sexual Preproduction and Meiosis
Sexual Preproduction and Meiosis

... • These terms refer to the number of sets of chromosomes an organism has. • Humans are Diploid, we have two sets of chromosomes 46 total or 23 Pairs of “Homologous” chromosomes • Sperm and eggs are haploid they only have 23 chromosomes each. • When sperm and egg join the resulting zygote will have 4 ...
< 1 ... 543 544 545 546 547 548 549 550 551 ... 1288 >

Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report