
Expression of death-related genes and reactive oxygen species
... The effects of 4E/Z-octadienal (OCTA) on ScDSP-1 and ScDSP-2 gene expression and reactive oxygen species (ROS) production were investigated in the marine diatom Skeletonema tropicum (formerly costatum) using qRTPCR and flow cytometry. ScDSP-1 and ScDSP-2 genes have been previously shown to be involv ...
... The effects of 4E/Z-octadienal (OCTA) on ScDSP-1 and ScDSP-2 gene expression and reactive oxygen species (ROS) production were investigated in the marine diatom Skeletonema tropicum (formerly costatum) using qRTPCR and flow cytometry. ScDSP-1 and ScDSP-2 genes have been previously shown to be involv ...
draft - University of Michigan
... al. 2012). This network was constructed by integrating TF binding motif conservation, ChIP-chip and ChIP-seq for TFs and chromatin marks, and microarray and RNA-seq measures of gene expression (Marbach et al. 2012). Using the edges in this network, we compared the proportion of X-linked target genes ...
... al. 2012). This network was constructed by integrating TF binding motif conservation, ChIP-chip and ChIP-seq for TFs and chromatin marks, and microarray and RNA-seq measures of gene expression (Marbach et al. 2012). Using the edges in this network, we compared the proportion of X-linked target genes ...
PDF of article
... that was discovered some decades ago, but its functional role in eukaryotes still awaits elucidation. 5-Hydroxymethylcytosine is an epigenetic marker that is crucial for multiple biological processes. The profile is altered under certain disease conditions such as cancer, Huntington’s disease and Al ...
... that was discovered some decades ago, but its functional role in eukaryotes still awaits elucidation. 5-Hydroxymethylcytosine is an epigenetic marker that is crucial for multiple biological processes. The profile is altered under certain disease conditions such as cancer, Huntington’s disease and Al ...
First mutation in the red blood cell-specific
... Utrecht), in a patient previously diagnosed with HK deficiency. To our knowledge, these three patients are the only ones in which the molecular basis has been studied. In all three cases mutations were located in that part of the gene that encodes both HK-R and HK-1. The erythroid-specific promoter ...
... Utrecht), in a patient previously diagnosed with HK deficiency. To our knowledge, these three patients are the only ones in which the molecular basis has been studied. In all three cases mutations were located in that part of the gene that encodes both HK-R and HK-1. The erythroid-specific promoter ...
"PCR-based Species Identification and Gene Tagging"
... Detection of infected progeny from a systemically infected maize plant via dot-blot hybridization using genomic P. sorghi gDNA ...
... Detection of infected progeny from a systemically infected maize plant via dot-blot hybridization using genomic P. sorghi gDNA ...
osb week10 lab
... White spotted, or piebald, cats are very common. Spotting may occur with any coat color, and is mainly due to the effect of one gene with two co-dominant alleles. The spotted allele, S, is phenotypically expressed as white spots, while the s allele is expressed as no white spots or even any white ha ...
... White spotted, or piebald, cats are very common. Spotting may occur with any coat color, and is mainly due to the effect of one gene with two co-dominant alleles. The spotted allele, S, is phenotypically expressed as white spots, while the s allele is expressed as no white spots or even any white ha ...
Modes of selection: directional, balancing and disruptive RR Rr rr
... (1) Most are “special-purpose” genes needed only under certain circumstances (stresses that occur in nature but not in the lab). (2) Most are “fine-tuning” genes that increase the efficiency or accuracy of some physiological or developmental process in most environments. ...
... (1) Most are “special-purpose” genes needed only under certain circumstances (stresses that occur in nature but not in the lab). (2) Most are “fine-tuning” genes that increase the efficiency or accuracy of some physiological or developmental process in most environments. ...
Warren, ST: Trinucleotide repetition and fragile X syndrome. Hospital Practice 32:73 - 98 (1997). cover illustration.
... As much as 3% of the human population is mentally retarded, and at least 300 genetic disorders include mental retardation. In seeking the genes involved, it has long been clear that males are at special risk--as much as three times greater than females. Thus, there has long been reason to suspect X- ...
... As much as 3% of the human population is mentally retarded, and at least 300 genetic disorders include mental retardation. In seeking the genes involved, it has long been clear that males are at special risk--as much as three times greater than females. Thus, there has long been reason to suspect X- ...
Chromosome Structure Variations
... for some genes and deleted for other genes. (They do have 1 centromere apiece though). The gametes resulting from these are aneuploid and do not survive. • Thus, either kind of inversion has lethal results when it crosses over with a normal chromosome. The only offspring that survive are those that ...
... for some genes and deleted for other genes. (They do have 1 centromere apiece though). The gametes resulting from these are aneuploid and do not survive. • Thus, either kind of inversion has lethal results when it crosses over with a normal chromosome. The only offspring that survive are those that ...
Structure of a DNA polymerase
... * Topoisomerases II change the linking number in steps of 2 by passing both strands of double-stranded DNA through a break. * Eukaryotic topoisomerases isolated to date only relax supercoiled DNA, while prokaryotic topoisomerases (gyrases) can, given ATP, add supercoils. * TopoII releases catenated ...
... * Topoisomerases II change the linking number in steps of 2 by passing both strands of double-stranded DNA through a break. * Eukaryotic topoisomerases isolated to date only relax supercoiled DNA, while prokaryotic topoisomerases (gyrases) can, given ATP, add supercoils. * TopoII releases catenated ...
DNA-dependent DNA polymerase (DDDP)
... • Many DNA fragments are synthesized sequentially on the DNA template strand having the 5´- end. These DNA fragments are called Okazaki fragments. They are 1000 – 2000 nt long for prokaryotes and 100-150 nt ...
... • Many DNA fragments are synthesized sequentially on the DNA template strand having the 5´- end. These DNA fragments are called Okazaki fragments. They are 1000 – 2000 nt long for prokaryotes and 100-150 nt ...
Integrated Analysis of Microarray Data and Gene Function Information.
... may represent one gene or a group of genes with same “response pattern”, which means the genes have the same 0 and 1 strings in their rows in the indicator table. Because the total squared lengths of the edges are minimized, the categories that have large intersection set are likely to be pulled tog ...
... may represent one gene or a group of genes with same “response pattern”, which means the genes have the same 0 and 1 strings in their rows in the indicator table. Because the total squared lengths of the edges are minimized, the categories that have large intersection set are likely to be pulled tog ...
in yeast pontecorvo, roper, hemmons, jacob
... at the first division, but the chromosomes do not separate into four separate nuclei at the second division. This may be due to nondisjunction or to restitution of the pairs of haploid telophase nuclei into two diploid nuclei. This is shown in Figure 3. The consequences of meiotic crossing over and ...
... at the first division, but the chromosomes do not separate into four separate nuclei at the second division. This may be due to nondisjunction or to restitution of the pairs of haploid telophase nuclei into two diploid nuclei. This is shown in Figure 3. The consequences of meiotic crossing over and ...
Article Positive Selection Underlies Faster-Z
... Fast-Z in gene expression; however, in contrast to coding sequence, our data indicate that Fast-Z in expression is due to positive selection acting primarily in females. In the soma, where gene expression is highly correlated between the sexes, we detected Fast-Z in both sexes, although at a higher ...
... Fast-Z in gene expression; however, in contrast to coding sequence, our data indicate that Fast-Z in expression is due to positive selection acting primarily in females. In the soma, where gene expression is highly correlated between the sexes, we detected Fast-Z in both sexes, although at a higher ...
Lac A
... LacIS repressor is always bound on the Operator repressing the transcription of Operon Lac : the operon Lac genes are not transcribed and expressed In order to analyse the phenotype I’ll grow the mutant in a condition where I can detect the expression of enzyme…with the presence of lactose (inductio ...
... LacIS repressor is always bound on the Operator repressing the transcription of Operon Lac : the operon Lac genes are not transcribed and expressed In order to analyse the phenotype I’ll grow the mutant in a condition where I can detect the expression of enzyme…with the presence of lactose (inductio ...
Stochastic Modeling of Chemical Reactions (and more
... For African honey bees: a1 = .3, a2 = .02, b1 = .015, b2 = .001 [Matis et al 1998] ...
... For African honey bees: a1 = .3, a2 = .02, b1 = .015, b2 = .001 [Matis et al 1998] ...
LDhat 2.2: A package for the population genetic analysis of
... table, pre-computed tables for a range of parameter values are available from http://ldhat.sourceforge.net/instructions.shtml • fin. Coalescent simulation program to generate data sets for analysis with LDhat. The principal novelty of the program is that it enables simulation of arbitrary mutation m ...
... table, pre-computed tables for a range of parameter values are available from http://ldhat.sourceforge.net/instructions.shtml • fin. Coalescent simulation program to generate data sets for analysis with LDhat. The principal novelty of the program is that it enables simulation of arbitrary mutation m ...
Document
... Post-Genome Informatics Classical Organisms have extensive Genetic Descriptions There will be NO more classical organisms beyond Mice and Men other than Worms and Flies, Yeasts and Weeds. So must use comparative genomics to classical organisms, Via sequence homologies and literature analysis. Autom ...
... Post-Genome Informatics Classical Organisms have extensive Genetic Descriptions There will be NO more classical organisms beyond Mice and Men other than Worms and Flies, Yeasts and Weeds. So must use comparative genomics to classical organisms, Via sequence homologies and literature analysis. Autom ...
Analysis and nucleotide sequence of an origin of DNA replication in
... pWH1266 and transformants were scored on LB plates containing 100/~gAp/ml. Competency is observed from the early log phase to the stationary phase. A maximum of competency is found in the late log phase of growth with about 6 × l0 s transformants per 500 ng of plasmid DNA. This procedure is slightly ...
... pWH1266 and transformants were scored on LB plates containing 100/~gAp/ml. Competency is observed from the early log phase to the stationary phase. A maximum of competency is found in the late log phase of growth with about 6 × l0 s transformants per 500 ng of plasmid DNA. This procedure is slightly ...
Genetic Inheritance - leavingcertbiology.net
... • Females have a pair of genes governing each trait – if one gene is faulty, then she has a second one to cover ...
... • Females have a pair of genes governing each trait – if one gene is faulty, then she has a second one to cover ...
Site-specific recombinase technology

Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse