
IJBT 11(4) 412-415
... rust (Puccinia triticina). It has been indicated that PBW65 expresses non-hypersensitive type of resistance against race 77-5. F2 and F3 crossing of PBW65 with WL711, a leaf rust susceptible wheat cultivar, and allelic tests with such already known genes (present in cultivars RL 6058 and HD 2009) re ...
... rust (Puccinia triticina). It has been indicated that PBW65 expresses non-hypersensitive type of resistance against race 77-5. F2 and F3 crossing of PBW65 with WL711, a leaf rust susceptible wheat cultivar, and allelic tests with such already known genes (present in cultivars RL 6058 and HD 2009) re ...
Tracking bacterial DNA replication forks in vivo by pulsed field gel
... 20% of the chromosome is devoid of Not I sites (i.e. compare 1000 kb with 868 kb). In addition, the experiments described below will show that the DNA replication origin and terminus as well as the genes described above appear to be arranged in a similar manner in the two isolates (K12 and 15). Iden ...
... 20% of the chromosome is devoid of Not I sites (i.e. compare 1000 kb with 868 kb). In addition, the experiments described below will show that the DNA replication origin and terminus as well as the genes described above appear to be arranged in a similar manner in the two isolates (K12 and 15). Iden ...
p2 - Glenelg High School
... does each of these formulas mean, and how are the formulas derived? p + q = 1: If you add all the dominant alleles for a gene to all the recessive alleles for the gene, you get all of the alleles for that gene, or 100% of the alleles for the gene. (Note: This assumes the gene has only two alleles.) ...
... does each of these formulas mean, and how are the formulas derived? p + q = 1: If you add all the dominant alleles for a gene to all the recessive alleles for the gene, you get all of the alleles for that gene, or 100% of the alleles for the gene. (Note: This assumes the gene has only two alleles.) ...
Functional SNPs in the SCGB3A2 promoter are
... Defining the GD susceptibility region by association analysis of a 3.0 Mb region surrounding marker D5s2090 To narrow down the GD susceptibility locus, we started with a 3.0 Mb region surrounding D5s2090, defined by a decrease in the LOD score of 1.5 or more with an 99% confidence interval for link ...
... Defining the GD susceptibility region by association analysis of a 3.0 Mb region surrounding marker D5s2090 To narrow down the GD susceptibility locus, we started with a 3.0 Mb region surrounding D5s2090, defined by a decrease in the LOD score of 1.5 or more with an 99% confidence interval for link ...
ppt
... Genetic manipulation of vectors Controversial but attractive and potentially selfpropagating. Many questions need to be addressed first about the feasibility and consequences of this approach. Serious issues are: reduced fitness of modified vectors, the ecological impact of transgenic arthropods an ...
... Genetic manipulation of vectors Controversial but attractive and potentially selfpropagating. Many questions need to be addressed first about the feasibility and consequences of this approach. Serious issues are: reduced fitness of modified vectors, the ecological impact of transgenic arthropods an ...
PubMed-EX: a web browser extension to enhance PubMed search
... on the maximum matching algorithm. We compiled a dictionary of about 40 000 disease terms with corresponding unique identifiers from the MeSH database. It achieves satisfactory F-score of 83.4% on Jimeno et al.’s (2008) corpus. Detailed results can be found in the Supplementary Material. 2.2.3 Relat ...
... on the maximum matching algorithm. We compiled a dictionary of about 40 000 disease terms with corresponding unique identifiers from the MeSH database. It achieves satisfactory F-score of 83.4% on Jimeno et al.’s (2008) corpus. Detailed results can be found in the Supplementary Material. 2.2.3 Relat ...
What is systems biology? - McGraw Hill Higher Education
... GAL 1, GAL 5, GAL 7, and GAL 10 genes encode four enzymes One transporter molecule carries galactose into cell Four transcription factors that turn the system on and off ...
... GAL 1, GAL 5, GAL 7, and GAL 10 genes encode four enzymes One transporter molecule carries galactose into cell Four transcription factors that turn the system on and off ...
Meiosis PowerPoint
... The Sexual Lifecycle--Humans Somatic cells are the cells other than the sperm and egg. Each one contains 46 c-somes (23 pairs, 1 pair from each parent). Each parent contributes 22 autosomes and 1 sex c-some. ...
... The Sexual Lifecycle--Humans Somatic cells are the cells other than the sperm and egg. Each one contains 46 c-somes (23 pairs, 1 pair from each parent). Each parent contributes 22 autosomes and 1 sex c-some. ...
Searching for Mobile Genetic Elements in the Genome of the
... TEs. There exists a strong possibility that this is in fact a TE that was passed through the marsupial linage by way of horizontal transfer. ...
... TEs. There exists a strong possibility that this is in fact a TE that was passed through the marsupial linage by way of horizontal transfer. ...
Dermatosparaxis type fact sheet
... Edvard Ehlers and Henri-Alexandre Danlos. Edvard Ehlers first described the syndrome as a separate entity in 1901. There are currently 6 main types of EDS: the arthrochalasia type the classic type the dermatosparaxis type the hypermobility type the kyphoscoliosis type the vascular type O ...
... Edvard Ehlers and Henri-Alexandre Danlos. Edvard Ehlers first described the syndrome as a separate entity in 1901. There are currently 6 main types of EDS: the arthrochalasia type the classic type the dermatosparaxis type the hypermobility type the kyphoscoliosis type the vascular type O ...
Isolation of DNA from A Single Helminth Using New Developed Kit
... low, when the worms were used for the DNA extraction promptly after removing from 70% ethanol solution. The important critical point for the DNA extraction is to ensure that the worm is well disrupted, homogenized, the cells are completely lysed and the DNA is free in the solution. Otherwise, the de ...
... low, when the worms were used for the DNA extraction promptly after removing from 70% ethanol solution. The important critical point for the DNA extraction is to ensure that the worm is well disrupted, homogenized, the cells are completely lysed and the DNA is free in the solution. Otherwise, the de ...
Using comparative genomic hybridization to
... such as GC content, also contribute to variation in hybridization ratio, as does technical variation. Conclusions: Here we demonstrate that aCGH can accurately be used as a proxy to estimate genome-wide divergence, thus providing an efficient way to evaluate how evolutionary processes and genomic ar ...
... such as GC content, also contribute to variation in hybridization ratio, as does technical variation. Conclusions: Here we demonstrate that aCGH can accurately be used as a proxy to estimate genome-wide divergence, thus providing an efficient way to evaluate how evolutionary processes and genomic ar ...
Application of rpoB sequence similarity analysis, REP‐PCR and
... the rpoB tree, both phylogenetic analyses shared satisfactory bootstrap support. In terms of the 16S rRNA gene sequences of Geobacillus and Bacillus type strains and isolates, similarity values among 90% and 100% were retrieved, in agreement with Zeigler (2005) who confirmed 16S rRNA gene sequences ...
... the rpoB tree, both phylogenetic analyses shared satisfactory bootstrap support. In terms of the 16S rRNA gene sequences of Geobacillus and Bacillus type strains and isolates, similarity values among 90% and 100% were retrieved, in agreement with Zeigler (2005) who confirmed 16S rRNA gene sequences ...
Mitochondrial DNA disease - Human Molecular Genetics
... exposure to ambient conditions (29). Therefore, it will be important to perform the manipulations in tightly controlled environmental conditions and to develop techniques to minimize the risk of inducing aneuploidy during transplantation of the metaphase II spindle. While pronuclear transfer offers ...
... exposure to ambient conditions (29). Therefore, it will be important to perform the manipulations in tightly controlled environmental conditions and to develop techniques to minimize the risk of inducing aneuploidy during transplantation of the metaphase II spindle. While pronuclear transfer offers ...
Mouse models of obesity
... function, leading to obesity. Targeted deletion of the Mc3r gene also results in a lateonset obesity phenotype, but regulation of appetite and metabolism appear to be intact.[29] Mc3r transgenic mouse also seem more susceptible to diet-induced obesity, with high-fat diets leading to significantly in ...
... function, leading to obesity. Targeted deletion of the Mc3r gene also results in a lateonset obesity phenotype, but regulation of appetite and metabolism appear to be intact.[29] Mc3r transgenic mouse also seem more susceptible to diet-induced obesity, with high-fat diets leading to significantly in ...
The genomic rate of adaptive evolution
... genetic variation, within a genomic region. Regions of low recombination are particularly prone to this process. Dn: the number of non-synonymous substitutions per gene. dn: the number of non-synonymous substitutions per site. An alternative symbol is Ka. Ds: the number of synonymous substitutions p ...
... genetic variation, within a genomic region. Regions of low recombination are particularly prone to this process. Dn: the number of non-synonymous substitutions per gene. dn: the number of non-synonymous substitutions per site. An alternative symbol is Ka. Ds: the number of synonymous substitutions p ...
genetic testing - NYU School of Medicine
... may have a birth defect. While this test is the most common prenatal test, it is also known to result in spontaneous abortion (about 1 in 400). D. Genetic Testing in Adults Carrier Testing These forms of genetic tests may be done with a physician and usually take place when a patient is considering ...
... may have a birth defect. While this test is the most common prenatal test, it is also known to result in spontaneous abortion (about 1 in 400). D. Genetic Testing in Adults Carrier Testing These forms of genetic tests may be done with a physician and usually take place when a patient is considering ...
2557-9370-1-RV
... and phylogenetic trees analysis of CAX families; Sequence were obtained from the GeneBank database. The accession number are listed in the Material and methods section. (B) The transmembrane domains in AtCAX4 were predicted by the TMHMM algorithm (http://www.cbs.dtu.dk/services/TMHMM/). ...
... and phylogenetic trees analysis of CAX families; Sequence were obtained from the GeneBank database. The accession number are listed in the Material and methods section. (B) The transmembrane domains in AtCAX4 were predicted by the TMHMM algorithm (http://www.cbs.dtu.dk/services/TMHMM/). ...
Regulatory genes
... Regulatory genes regulate the expression of ot her genes. For example, a regulatory gene may ‘silence’ another gene from expressing its dominant trait. The Manx cat has no tail because it has a r egulatory gene that silences the gene that e xpresses the tail. This tail silencing gene is d ominant an ...
... Regulatory genes regulate the expression of ot her genes. For example, a regulatory gene may ‘silence’ another gene from expressing its dominant trait. The Manx cat has no tail because it has a r egulatory gene that silences the gene that e xpresses the tail. This tail silencing gene is d ominant an ...
Computational Biology
... This lecture rounds up the first block of the Bioinformatics III course on genome structure, rearrangements etc. Next block until Christmas: gene finding, SNPs, functional genomics 8. Lecture WS 2003/04 ...
... This lecture rounds up the first block of the Bioinformatics III course on genome structure, rearrangements etc. Next block until Christmas: gene finding, SNPs, functional genomics 8. Lecture WS 2003/04 ...
Origin of the Science of genetics
... "disappear" in F1 pea plants? 3. Assuming complete dominance, the F2 generation following the cross Aa x Aa will show a phenotypic ratio of _____ . 4. In meiosis what happens to chromosome from each homologous pair? ...
... "disappear" in F1 pea plants? 3. Assuming complete dominance, the F2 generation following the cross Aa x Aa will show a phenotypic ratio of _____ . 4. In meiosis what happens to chromosome from each homologous pair? ...
Origin of the Science of genetics
... "disappear" in F1 pea plants? 3. Assuming complete dominance, the F2 generation following the cross Aa x Aa will show a phenotypic ratio of _____ . 4. In meiosis what happens to chromosome from each homologous pair? ...
... "disappear" in F1 pea plants? 3. Assuming complete dominance, the F2 generation following the cross Aa x Aa will show a phenotypic ratio of _____ . 4. In meiosis what happens to chromosome from each homologous pair? ...
Domestication genes in plants
... Domestication is a process • The distinction ‘domesticated’ or ‘not domesticated’ is an oversimplification • Some crops have moved further along this process further than others. • We can recognize different levels of domestication • How can we decide which level? ...
... Domestication is a process • The distinction ‘domesticated’ or ‘not domesticated’ is an oversimplification • Some crops have moved further along this process further than others. • We can recognize different levels of domestication • How can we decide which level? ...
Site-specific recombinase technology

Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse