Corchorus yellow vein virus, a New World geminivirus from the Old
... identical between components of each individual virus. These comprise iterative sequences (iterons) that are recognized and bound by Rep protein (Fontes et al., 1994; Orozco et al., 1998) and a conserved inverted repeat sequence with the potential to form a stem–loop where rolling circle replication ...
... identical between components of each individual virus. These comprise iterative sequences (iterons) that are recognized and bound by Rep protein (Fontes et al., 1994; Orozco et al., 1998) and a conserved inverted repeat sequence with the potential to form a stem–loop where rolling circle replication ...
View/Open - Cadair - Aberystwyth University
... MYB3R1, MYB3R3, and MYB3R5 act redundantly as transcriptional repressors Phylogenetic analysis showed that there are two evolutionarily conserved groups in plant MYB3R family (Fig 1A). One contains MYB3R1 and MYB3R4 (hereafter MYB3R1/4) from Arabidopsis, which were previously shown to act as transcr ...
... MYB3R1, MYB3R3, and MYB3R5 act redundantly as transcriptional repressors Phylogenetic analysis showed that there are two evolutionarily conserved groups in plant MYB3R family (Fig 1A). One contains MYB3R1 and MYB3R4 (hereafter MYB3R1/4) from Arabidopsis, which were previously shown to act as transcr ...
Some Calpain History- Part 2: GENETICS and EVOLUTION
... The information for calpain genetics is organized by genes for component subunits of calpain-1 (Capn1 and Capns1), calpain-2 (Capn2 and Capns1) and calpastatin (Cast) Capn3 – a genetic link to human disease- Limb-Girdle Muscular Dystrophy type IIA Capn10- a genetic link to human disease- type ...
... The information for calpain genetics is organized by genes for component subunits of calpain-1 (Capn1 and Capns1), calpain-2 (Capn2 and Capns1) and calpastatin (Cast) Capn3 – a genetic link to human disease- Limb-Girdle Muscular Dystrophy type IIA Capn10- a genetic link to human disease- type ...
Data-driven integration of epidemiological and toxicological data to
... Fig. 1. Method of integrating epidemiological and toxicological data to create variant by environment interaction candidates. (A) Summary of epidemiological databases, VARIMED (source of genetic associations, red) and NHANES (source of environmental data, green). (B) Factors are chosen by their stre ...
... Fig. 1. Method of integrating epidemiological and toxicological data to create variant by environment interaction candidates. (A) Summary of epidemiological databases, VARIMED (source of genetic associations, red) and NHANES (source of environmental data, green). (B) Factors are chosen by their stre ...
Factors Affecting synonymous codon Usage Bias in chloroplast
... plant nuclear genes and in chloroplasts.32 Chloroplasts differ from the nuclear genome of higher plants in that they encode only 30 tRNA species. Since chloroplasts have restricted their tRNA genes, the use of preferred codons by chloroplast encoded proteins appears more extreme. However, a positive ...
... plant nuclear genes and in chloroplasts.32 Chloroplasts differ from the nuclear genome of higher plants in that they encode only 30 tRNA species. Since chloroplasts have restricted their tRNA genes, the use of preferred codons by chloroplast encoded proteins appears more extreme. However, a positive ...
1 Article: Investigation Evidence for Stabilizing Selection on Codon
... evidence suggests that this is non-uniform across an inversion, as genetic flux among arrangements has been observed within the boundaries of inversion breakpoints resulting from gene conversion or of double crossovers (Kovacevic and Schaeffer 2000; Andolfatto et al. 2001; Schaeffer et al. 2003; Ken ...
... evidence suggests that this is non-uniform across an inversion, as genetic flux among arrangements has been observed within the boundaries of inversion breakpoints resulting from gene conversion or of double crossovers (Kovacevic and Schaeffer 2000; Andolfatto et al. 2001; Schaeffer et al. 2003; Ken ...
A pseudogene cluster in the leader region of the Euglena
... -like cloverleaf structure but has changed considerably from the functional counterpart, both in terms of alternations in Invariant sites and 1n loss of base pairing 1n stem regions. These alternations rendered 1t unable to function normally, and thus this gene was identified as a pseudogene. Simila ...
... -like cloverleaf structure but has changed considerably from the functional counterpart, both in terms of alternations in Invariant sites and 1n loss of base pairing 1n stem regions. These alternations rendered 1t unable to function normally, and thus this gene was identified as a pseudogene. Simila ...
Coordinated repression and activation of two
... somatic and visceral muscles (Giesen et al., 1997; Murawsky et al., 2001). We confirmed this observation and, in addition, found that Futsch is also misexpressed in the cardiac mesoderm (supplementary material Fig. S2), suggesting that ttk might be expressed at subdetectable levels in the heart and/ ...
... somatic and visceral muscles (Giesen et al., 1997; Murawsky et al., 2001). We confirmed this observation and, in addition, found that Futsch is also misexpressed in the cardiac mesoderm (supplementary material Fig. S2), suggesting that ttk might be expressed at subdetectable levels in the heart and/ ...
A whole-genome assembly of the domestic cow, Bos taurus
... Having an accurate assembly of the genome of an important species provides an invaluable substrate for future research. For example, studies of genetic diversity need a good reference genome in order to catalog differences in new strains or lineages. Expression analyses that sequence RNA from variou ...
... Having an accurate assembly of the genome of an important species provides an invaluable substrate for future research. For example, studies of genetic diversity need a good reference genome in order to catalog differences in new strains or lineages. Expression analyses that sequence RNA from variou ...
Chapter 14: Mendel and the Gene Idea
... Before we begin: Define these terms: Gene: functional unit of heredity - a segment of DNA located in a specific site on a chromosome that gives the instrcutions to make one (or more) enzyme or other protein. Dive into the chromosome here! ! Phenotype: Observable characteristics of an organism, for ...
... Before we begin: Define these terms: Gene: functional unit of heredity - a segment of DNA located in a specific site on a chromosome that gives the instrcutions to make one (or more) enzyme or other protein. Dive into the chromosome here! ! Phenotype: Observable characteristics of an organism, for ...
GENETICS TEST II - Daytona State College
... moths/butterflies, fish, reptiles, and amphibians. • The presence of one Z chromsome and one W chromosome (ZW) results in female offspring. (heterogametic) • The presence of two X chromsomes (ZZ) in the zygote results in male offspring (homogametic). • All male gametes have an Z chromosome, female g ...
... moths/butterflies, fish, reptiles, and amphibians. • The presence of one Z chromsome and one W chromosome (ZW) results in female offspring. (heterogametic) • The presence of two X chromsomes (ZZ) in the zygote results in male offspring (homogametic). • All male gametes have an Z chromosome, female g ...
Codon - Ziheng Yang
... c Parameters in parentheses are not free parameters. d PSS is the number of positive selection sites. The first number is the PSS with posterior probabilities > 50%. The second number, in parentheses, is the PSS with posterior probabilities > ...
... c Parameters in parentheses are not free parameters. d PSS is the number of positive selection sites. The first number is the PSS with posterior probabilities > 50%. The second number, in parentheses, is the PSS with posterior probabilities > ...
Pairwise sequence alignment - uni
... The process of lining up two sequences to achieve maximal levels of identity (and conservation, for amino acid sequences) for the purpose of assessing the degree of similarity and the possibility of homology. ...
... The process of lining up two sequences to achieve maximal levels of identity (and conservation, for amino acid sequences) for the purpose of assessing the degree of similarity and the possibility of homology. ...
Deprivation of protein or amino acid induces C/EBPβ synthesis and
... but not completely inhibit, the AARE-enhanced transcription [12]. However, additional data to support the proposal that C/EBPβ acts as a suppressor, rather than its more common function of activation, is necessary. The C/EBP family of transcription proteins represents a subclass of the bZIP (basic l ...
... but not completely inhibit, the AARE-enhanced transcription [12]. However, additional data to support the proposal that C/EBPβ acts as a suppressor, rather than its more common function of activation, is necessary. The C/EBP family of transcription proteins represents a subclass of the bZIP (basic l ...
I Gregor Mendel - Nutley Public Schools
... 2. If an organism heterozygous for two traits is crossed with another recessive for both traits, expected phenotypic ratio is ________________ 3. In dihybrid genetics problems, the individual has ________________, two for each trait. IV. Mendelism and the Genotype A. Incomplete Dominance and Codomin ...
... 2. If an organism heterozygous for two traits is crossed with another recessive for both traits, expected phenotypic ratio is ________________ 3. In dihybrid genetics problems, the individual has ________________, two for each trait. IV. Mendelism and the Genotype A. Incomplete Dominance and Codomin ...
A unique pattern of intrastrand anomalies in base
... DNA are islands of purine richness in which A>T and G>C. These islands may serve as signals for the excision of macronuclear molecules during macronuclear development. We have found no published reports of coding or non-coding native DNA with such anomalous base composition. INTRODUCTION The DNA in ...
... DNA are islands of purine richness in which A>T and G>C. These islands may serve as signals for the excision of macronuclear molecules during macronuclear development. We have found no published reports of coding or non-coding native DNA with such anomalous base composition. INTRODUCTION The DNA in ...
Commentaries on Viewpoint: Epigenetic regulation of the ACE gene
... because the definition of the “elite athlete” and the heterogeneity of the elite athlete phenotype may be variable. It is not clear how the ACE I/D polymorphism contributes to the enzyme level, nevertheless, in some cases it is known that the D allele mRNA is more abundant that the I allele mRNA (5) ...
... because the definition of the “elite athlete” and the heterogeneity of the elite athlete phenotype may be variable. It is not clear how the ACE I/D polymorphism contributes to the enzyme level, nevertheless, in some cases it is known that the D allele mRNA is more abundant that the I allele mRNA (5) ...
Nature vs. Nurture: Behavioral Genetics and the Law
... expert testified that there were “no genetic factors” that “might predispose BB to violence;” nobody objected to this testimony DD: High activity MAOA; heterozygous for SLC6A4; court suggested that genetic testing could become necessary component of defense FF: High activity MAOA; short SLC6A4 allel ...
... expert testified that there were “no genetic factors” that “might predispose BB to violence;” nobody objected to this testimony DD: High activity MAOA; heterozygous for SLC6A4; court suggested that genetic testing could become necessary component of defense FF: High activity MAOA; short SLC6A4 allel ...
DNA behind coat colors - American Shetland Sheepdog Association
... appearance of the dog is the same whether the dog is homozygous or heterozygous. An example of this is the sable coat color. Recessive alleles are those that are expressed only when two copies of the allele are present. For example, bicolor is recessive. When more than two alleles are present in a b ...
... appearance of the dog is the same whether the dog is homozygous or heterozygous. An example of this is the sable coat color. Recessive alleles are those that are expressed only when two copies of the allele are present. For example, bicolor is recessive. When more than two alleles are present in a b ...
Molecular Characterization of a Zygote Wall
... as GCCAGCCSG. An informal survey of various Chlamydomonas nuclear genes indicates that only the adenosine positioned three nucleotides upstream of the AUG is highly conserved. This situation is similar to that in yeast mRNA sequences (Kozak, 1989). Restriction mapping data from both the genomic and ...
... as GCCAGCCSG. An informal survey of various Chlamydomonas nuclear genes indicates that only the adenosine positioned three nucleotides upstream of the AUG is highly conserved. This situation is similar to that in yeast mRNA sequences (Kozak, 1989). Restriction mapping data from both the genomic and ...
Document
... and accumulates in the nuclear periphery.4 Progerin is then able intercalate into the nuclear membrane and dimerize with normal lamin A to form a protein complex that disrupts the intended protein scaffolding function; this results in the abnormal nuclear morphology characteristic of HGPS.1 ...
... and accumulates in the nuclear periphery.4 Progerin is then able intercalate into the nuclear membrane and dimerize with normal lamin A to form a protein complex that disrupts the intended protein scaffolding function; this results in the abnormal nuclear morphology characteristic of HGPS.1 ...
Supplementary Notes S1 (doc 64K)
... polymorphisms listed in the DGV (version- variation.hg18.v10.nov.2010) as described above. Primers were designed using Primer Express (Applied Biosystems) and purchased from Integrated DNA Technologies (www.idtdna.com) in lab ready format. The patient's DNA was diluted in PCR-grade water, and the qu ...
... polymorphisms listed in the DGV (version- variation.hg18.v10.nov.2010) as described above. Primers were designed using Primer Express (Applied Biosystems) and purchased from Integrated DNA Technologies (www.idtdna.com) in lab ready format. The patient's DNA was diluted in PCR-grade water, and the qu ...
Molecular Characterization of a Zygote Wall Protein
... as GCCAGCCSG. An informal survey of various Chlamydomonas nuclear genes indicates that only the adenosine positioned three nucleotides upstream of the AUG is highly conserved. This situation is similar to that in yeast mRNA sequences (Kozak, 1989). Restriction mapping data from both the genomic and ...
... as GCCAGCCSG. An informal survey of various Chlamydomonas nuclear genes indicates that only the adenosine positioned three nucleotides upstream of the AUG is highly conserved. This situation is similar to that in yeast mRNA sequences (Kozak, 1989). Restriction mapping data from both the genomic and ...
Example of a poster - University of Florida
... and accumulates in the nuclear periphery.4 Progerin is then able intercalate into the nuclear membrane and dimerize with normal lamin A to form a protein complex that disrupts the intended protein scaffolding function; this results in the abnormal nuclear morphology characteristic of HGPS.1 ...
... and accumulates in the nuclear periphery.4 Progerin is then able intercalate into the nuclear membrane and dimerize with normal lamin A to form a protein complex that disrupts the intended protein scaffolding function; this results in the abnormal nuclear morphology characteristic of HGPS.1 ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse