SERIES ‘‘GENETICS OF ASTHMA AND COPD IN THE POSTGENOME ERA’’
... gene-targeted mouse with normal development but spontaneous emphysema with ageing. This represents another use of gene-targeted mice to determine important molecules and pathways in COPD. Limitations of transgenic and gene-targeted mice Transgenic technology depends upon random introduction of the g ...
... gene-targeted mouse with normal development but spontaneous emphysema with ageing. This represents another use of gene-targeted mice to determine important molecules and pathways in COPD. Limitations of transgenic and gene-targeted mice Transgenic technology depends upon random introduction of the g ...
Trachemys scripta elegans Red-Eared Turtle ( Fc)
... IgY is a low m.w. serum Ab encoded by the y gene in nonmammalian tetrapods, including birds (6–8), reptiles (9, 10), and amphibians (11–14). The gene is thought to have developed from m by a duplication event (2, 15) because of their sequence homology and similar gene structures. It is also thought ...
... IgY is a low m.w. serum Ab encoded by the y gene in nonmammalian tetrapods, including birds (6–8), reptiles (9, 10), and amphibians (11–14). The gene is thought to have developed from m by a duplication event (2, 15) because of their sequence homology and similar gene structures. It is also thought ...
Identification of editing positions in the ndhB transcript from maize
... chloroplasts shows that the ndhB transcript Is edited by C-to-U transitions at six positions which appear to exist as editing sites also in the chloroplast ndhB genes from rice and tobacco but not from liverwort. In order to identify possible sequence determinants necessary for editing, the sequence ...
... chloroplasts shows that the ndhB transcript Is edited by C-to-U transitions at six positions which appear to exist as editing sites also in the chloroplast ndhB genes from rice and tobacco but not from liverwort. In order to identify possible sequence determinants necessary for editing, the sequence ...
Gene expression patterns in human placenta
... complement inhibitor, Crry, which is similar to MCP and CD55. Deletion of Crry leads to death in utero, with C3 deposited on the placenta and marked invasion of inflammatory cells into the placenta (27). Also, the amnion compared with the chorion is remarkably nonimmunogenic: the amniotic membrane t ...
... complement inhibitor, Crry, which is similar to MCP and CD55. Deletion of Crry leads to death in utero, with C3 deposited on the placenta and marked invasion of inflammatory cells into the placenta (27). Also, the amnion compared with the chorion is remarkably nonimmunogenic: the amniotic membrane t ...
Genetic Algorithms - Iust personal webpages
... cells all with the same genetic contents Although all cells contain the same genes, depending on, for example where they are in the organism, they will behave differently This process of differential behaviour during development is called ontogenesis All of this uses, and is controlled by, the same ...
... cells all with the same genetic contents Although all cells contain the same genes, depending on, for example where they are in the organism, they will behave differently This process of differential behaviour during development is called ontogenesis All of this uses, and is controlled by, the same ...
A Protein - Cygnus Technologies
... using PicoGreen® Solution. Test samples should be diluted to 1mg/mL total protein prior to performing the DNA extraction. We recommend running the test samples at ~1mg/mL of total protein, however higher concentrations can be performed if assay qualification allows. 2. The PicoGreen® Solution will b ...
... using PicoGreen® Solution. Test samples should be diluted to 1mg/mL total protein prior to performing the DNA extraction. We recommend running the test samples at ~1mg/mL of total protein, however higher concentrations can be performed if assay qualification allows. 2. The PicoGreen® Solution will b ...
Ectopic expression of the PttKN1 gene in Cardamine hirsuta
... in C. hirsuta (Hay & Tsiantis, 2006; Canales et al., 2010), and that this species could be a new model system for studying compound leaf development (Barkoulas et al., 2008; Canales et al., 2010). In the present study, conserved domain was identified in the PttKN1 protein sequence, and then they wer ...
... in C. hirsuta (Hay & Tsiantis, 2006; Canales et al., 2010), and that this species could be a new model system for studying compound leaf development (Barkoulas et al., 2008; Canales et al., 2010). In the present study, conserved domain was identified in the PttKN1 protein sequence, and then they wer ...
Resurrection in cosmetics
... Figure 1: The resurrection fern Selaginella lepidophylla in the dry state (left) and two days after watering. ...
... Figure 1: The resurrection fern Selaginella lepidophylla in the dry state (left) and two days after watering. ...
Document
... Therapeutic targets (except for gene therapy) are phenotypic. Nonsymptomatic diagnosis where disease phenotype is not (yet) expressed may raise ethical concerns. Most disease and normal traits are multicomponent systems. ...
... Therapeutic targets (except for gene therapy) are phenotypic. Nonsymptomatic diagnosis where disease phenotype is not (yet) expressed may raise ethical concerns. Most disease and normal traits are multicomponent systems. ...
Identifying 3D expression domains by graph clustering
... These expression levels help identify the state of the chromatin, as ‘closed’ chromatin will result in lower expression levels compared to ‘open’ chromatin. Before the publication of the TRIP method this generally required low throughput analyses as reporters could only target specific genomic l ...
... These expression levels help identify the state of the chromatin, as ‘closed’ chromatin will result in lower expression levels compared to ‘open’ chromatin. Before the publication of the TRIP method this generally required low throughput analyses as reporters could only target specific genomic l ...
Microbiology
... A series of transposons are described which contain the gusA gene, encoding B-glucuronidase (GUS), expressed from a variety of promoters, both regulated and constitutive. The regulated promoters include the tac promoter which can be induced by IPTG, and nifH promoters which are symbiotically activat ...
... A series of transposons are described which contain the gusA gene, encoding B-glucuronidase (GUS), expressed from a variety of promoters, both regulated and constitutive. The regulated promoters include the tac promoter which can be induced by IPTG, and nifH promoters which are symbiotically activat ...
Pearl millet, food for the future in the Sahel
... one species to another, the PHYC gene and those governing flowering time, and also certain morphological traits such as spike length and stem diameter. Flowering time was strongly linked to climatic conditions: a long flowering time was better adapted to more humid climates, a shorter one suitable f ...
... one species to another, the PHYC gene and those governing flowering time, and also certain morphological traits such as spike length and stem diameter. Flowering time was strongly linked to climatic conditions: a long flowering time was better adapted to more humid climates, a shorter one suitable f ...
Document
... 11) Lesson. Role of small dose radiation effects and biological types of reaction of body. 11) practical (laboratory) lesson. To use of biological dosimeter method. 11)Quiz 12) Lesson. Positive results of adaptation and homeosis processing to small dose irradiated effect on body. 12) practical (labo ...
... 11) Lesson. Role of small dose radiation effects and biological types of reaction of body. 11) practical (laboratory) lesson. To use of biological dosimeter method. 11)Quiz 12) Lesson. Positive results of adaptation and homeosis processing to small dose irradiated effect on body. 12) practical (labo ...
The Expression in Staphylococcus aureus of Cloned DNA Encoding
... resistant/sensitive strain pair constructed by transduction. Furthermore, MF5 showed strong homology to a mec-associated fragment of identical length and endonuclease map which had been cloned independently by Beck et al. (1986). MF5 was later shown to be present at one end of a larger section of ch ...
... resistant/sensitive strain pair constructed by transduction. Furthermore, MF5 showed strong homology to a mec-associated fragment of identical length and endonuclease map which had been cloned independently by Beck et al. (1986). MF5 was later shown to be present at one end of a larger section of ch ...
Biotechnology Explorer™ Ligation and Transformation - Bio-Rad
... • Screening — When bacteria are being transformed with a ligation reaction, not all of the religated vectors will necessarily contain the DNA fragment of interest. To produce visible indicators that cells contain an insert, vectors frequently contain reporter genes, which distinguish them from cell ...
... • Screening — When bacteria are being transformed with a ligation reaction, not all of the religated vectors will necessarily contain the DNA fragment of interest. To produce visible indicators that cells contain an insert, vectors frequently contain reporter genes, which distinguish them from cell ...
Molecular Genetics of Alcohol-Related Brain Damage
... deficiency comparable to other hereditary metabolic disorders. The aim of this paper is to review the most recent knowledge on the genetic susceptibility to the development of alcohol-related Wernicke–Korsakoff syndrome (WKS). Methods: A literature review was carried out looking at the molecular gen ...
... deficiency comparable to other hereditary metabolic disorders. The aim of this paper is to review the most recent knowledge on the genetic susceptibility to the development of alcohol-related Wernicke–Korsakoff syndrome (WKS). Methods: A literature review was carried out looking at the molecular gen ...
Quantitative analysis of NOR expression in a B chromosome of the
... B chromosomes are supernumerary (accessory) chromosomes found in some individuals of about 15% of eukaryote species, which frequently show drive (i.e., higher transmission rate than standard (A) chromosomes) and decrease the fitness of individuals carrying them, thus behaving as genome parasites (fo ...
... B chromosomes are supernumerary (accessory) chromosomes found in some individuals of about 15% of eukaryote species, which frequently show drive (i.e., higher transmission rate than standard (A) chromosomes) and decrease the fitness of individuals carrying them, thus behaving as genome parasites (fo ...
chapter 23 - Scranton Prep Biology
... 5. No natural selection. All genotypes are equal in survival and reproductive success.Differential reproductivesuccesscan alter gene frequencies. In real populations, several factors can upset Hardy-Weinberg equilibrium and cause microevolut ionary change. Microevolution : Small scale evolutionary c ...
... 5. No natural selection. All genotypes are equal in survival and reproductive success.Differential reproductivesuccesscan alter gene frequencies. In real populations, several factors can upset Hardy-Weinberg equilibrium and cause microevolut ionary change. Microevolution : Small scale evolutionary c ...
- Wiley Online Library
... nodular heterotopia or they may be the direct result of the combined deletion/duplication of genes specific to our patient’s particular chromosomal aberration. None of the reported cases with deletions or duplications similar to those constituting our patient’s set of modifications had periventricul ...
... nodular heterotopia or they may be the direct result of the combined deletion/duplication of genes specific to our patient’s particular chromosomal aberration. None of the reported cases with deletions or duplications similar to those constituting our patient’s set of modifications had periventricul ...
Arabidopsis thaliana Arabidopsis thaliana
... hydraulics in a wide range of plant processes. - Compared with other sequenced organisms, Arabidopsis has 10-fold more predicted peptide transporters, primarily of the proton-dependent oligopeptide transport (POT) family, emphasizing the importance of peptide transport or indicating that there is br ...
... hydraulics in a wide range of plant processes. - Compared with other sequenced organisms, Arabidopsis has 10-fold more predicted peptide transporters, primarily of the proton-dependent oligopeptide transport (POT) family, emphasizing the importance of peptide transport or indicating that there is br ...
Kernels for gene regulatory regions
... start from a set of genes known to be similarly regulated, for example by clustering gene expression data, and search for over-represented short sequences in their proximal intergenic regions. Alternatively, some authors have proposed to represent each intergenic sequence by its content in short se ...
... start from a set of genes known to be similarly regulated, for example by clustering gene expression data, and search for over-represented short sequences in their proximal intergenic regions. Alternatively, some authors have proposed to represent each intergenic sequence by its content in short se ...
Impact of genetic engineering on the understanding of
... (Tyro3, Axl and Mer) and their simultaneous inactivation had led to azoospermia (Lu et al., 1999). Alternatives are to create conditional genome alterations by controlling their onset, frequency, spatial location and tissue/cell type speci®city. To avoid potential transcriptional interference, point ...
... (Tyro3, Axl and Mer) and their simultaneous inactivation had led to azoospermia (Lu et al., 1999). Alternatives are to create conditional genome alterations by controlling their onset, frequency, spatial location and tissue/cell type speci®city. To avoid potential transcriptional interference, point ...
Supplementary Methods Tables
... TCGA data at the DCC is organized by platform, data type and data level. Each platform may produce several types of data. For example, SNP-based platforms yield three data types: SNP, Copy Number Results, and Loss of Heterozygosity (LOH). The TCGA concept of data level segregates raw data from deriv ...
... TCGA data at the DCC is organized by platform, data type and data level. Each platform may produce several types of data. For example, SNP-based platforms yield three data types: SNP, Copy Number Results, and Loss of Heterozygosity (LOH). The TCGA concept of data level segregates raw data from deriv ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse