The Drosophila serum response factor homolog is required for formation of intervein tissue of the wing and is allelic to blistered. Development 122, 2589-2597. pdf
... 1996). All blistered alleles were kindly provided by D. Fristrom (Fristrom et al., 1994 and unpublished results). Homozygous lethal excision alleles from a P-element insertion in slbo were generously provided by D. Eberl and L. M. Hall. The slbo transcription unit (Montell et al., 1992) maps approxi ...
... 1996). All blistered alleles were kindly provided by D. Fristrom (Fristrom et al., 1994 and unpublished results). Homozygous lethal excision alleles from a P-element insertion in slbo were generously provided by D. Eberl and L. M. Hall. The slbo transcription unit (Montell et al., 1992) maps approxi ...
Neuroendocrine Gene Regulation in Hypothalamic Cell Lines
... were viewed as ‘feeding’ or ‘satiety’ centers. However, as our knowledge expanded, studies revealed that these ‘feeding’ and ‘satiety’ centers were comprised of a complex array of distinct neuronal populations, expressing a specific complement of neuropeptides, neurotransmitters and receptors that r ...
... were viewed as ‘feeding’ or ‘satiety’ centers. However, as our knowledge expanded, studies revealed that these ‘feeding’ and ‘satiety’ centers were comprised of a complex array of distinct neuronal populations, expressing a specific complement of neuropeptides, neurotransmitters and receptors that r ...
Carnitine Palmitoyltransferase CPT2 Deficiency (CPT2 Deficiency)
... gene detects >95% of patients with CPT2 deficiency. The sensitivity of DNA sequencing is over 99% for the detection of nucleotide base changes, small deletions and insertions in the regions analyzed. Mutations in regulatory regions or other untranslated regions are not detected by this test. Large d ...
... gene detects >95% of patients with CPT2 deficiency. The sensitivity of DNA sequencing is over 99% for the detection of nucleotide base changes, small deletions and insertions in the regions analyzed. Mutations in regulatory regions or other untranslated regions are not detected by this test. Large d ...
Genetics of ankylosing spondylitis
... complex segregation analysis has demonstrated a high degree of genetic control of disease severity assessed by the Bath AS Disease Activity index (BASDAI) and functional impairment assessed by the Bath AS Functional Index (BASFI) (4). Heritability of these measures was estimated at 51% and 68% respe ...
... complex segregation analysis has demonstrated a high degree of genetic control of disease severity assessed by the Bath AS Disease Activity index (BASDAI) and functional impairment assessed by the Bath AS Functional Index (BASFI) (4). Heritability of these measures was estimated at 51% and 68% respe ...
Genomic Analysis of Hox Clusters in the Sea Lamprey
... Gene orthology The entire homeobox was sequenced from each clone, which had a unique restriction map. Nucleotide sequences are available in GenBank, accession numbers AF410908–AF410925. The deduced amino acid sequences are shown aligned to mouse and amphioxus sequences in Figure 2. To assign genes t ...
... Gene orthology The entire homeobox was sequenced from each clone, which had a unique restriction map. Nucleotide sequences are available in GenBank, accession numbers AF410908–AF410925. The deduced amino acid sequences are shown aligned to mouse and amphioxus sequences in Figure 2. To assign genes t ...
Transformation of Maize Cells and Regeneration of
... gene bar. The Streptomyces hygroscopicus bar gene encodes phosphinothricin acetyltransferase (PAT), an enzyme that inactivates the herbicidal compound phosphinothricin (PPT) by acetylation (Murakami et ai., 1986; Thompson et ai., 1987). PPT inhibits glutamine synthetase (Tachibana et ai., 1986a), ca ...
... gene bar. The Streptomyces hygroscopicus bar gene encodes phosphinothricin acetyltransferase (PAT), an enzyme that inactivates the herbicidal compound phosphinothricin (PPT) by acetylation (Murakami et ai., 1986; Thompson et ai., 1987). PPT inhibits glutamine synthetase (Tachibana et ai., 1986a), ca ...
Gene Section MELK (maternal embryonic leucine zipper kinase) in Oncology and Haematology
... diverse functions such as cell cycle, cytokinesis, mRNA splicing and apoptosis. ...
... diverse functions such as cell cycle, cytokinesis, mRNA splicing and apoptosis. ...
Environmental Pollution
... This heap originates from the residuals of below-ground mining performed between 1905 and 1926 (Horst and Redel, 1977). The soil surrounding this heap supports the typical belt formation of plants dependent upon the salt concentration, with a surprisingly high richness of different halophytes. Soil ...
... This heap originates from the residuals of below-ground mining performed between 1905 and 1926 (Horst and Redel, 1977). The soil surrounding this heap supports the typical belt formation of plants dependent upon the salt concentration, with a surprisingly high richness of different halophytes. Soil ...
Development Duplication
... On August 14, 2013, the American Angus Association released results of a new genetic condition, referred to as Developmental Duplication (“DD”). The studies were conducted by Dr. Jonathan Beever of the ...
... On August 14, 2013, the American Angus Association released results of a new genetic condition, referred to as Developmental Duplication (“DD”). The studies were conducted by Dr. Jonathan Beever of the ...
the contribution of gene movement to the two rules of speciation
... introduce these mechanisms below, returning to the evidence for each in the next section. There are three mechanisms by which genes can move between chromosomes. The first involves the simple movement of a gene from one chromosome to another with no duplicative intermediate. Movement of large chromo ...
... introduce these mechanisms below, returning to the evidence for each in the next section. There are three mechanisms by which genes can move between chromosomes. The first involves the simple movement of a gene from one chromosome to another with no duplicative intermediate. Movement of large chromo ...
Document
... encode the twenty standard amino acids, giving most amino acids more than one possible codon. There are also three 'stop' or 'nonsense' codons signifying the end of the coding region; these are the TAA, TGA and TAG codons. ...
... encode the twenty standard amino acids, giving most amino acids more than one possible codon. There are also three 'stop' or 'nonsense' codons signifying the end of the coding region; these are the TAA, TGA and TAG codons. ...
Inference of homologous recombination in bacteria using whole
... locations where recombination occurred. The implementation of that method in software is called ClonalFrame [13]. ClonalFrame has proved useful to identify interesting patterns of recombination in a wide variety of organisms including Campylobacter [14], Neisseria [15] and Francisella [16]. In order ...
... locations where recombination occurred. The implementation of that method in software is called ClonalFrame [13]. ClonalFrame has proved useful to identify interesting patterns of recombination in a wide variety of organisms including Campylobacter [14], Neisseria [15] and Francisella [16]. In order ...
Tobacco TTG2 regulates vegetative growth and seed production via
... and Gretchen Hagen 3 (GH3) gene families [31–33]. Different ARFs regulate the expression of target genes by binding the auxin response elements, TGTCTC, GAGACA [29, 34, 35], or TGTCT [26] that are present in target promoters. These elements have numerous potential combinations with ARFs [4, 19, 30], ...
... and Gretchen Hagen 3 (GH3) gene families [31–33]. Different ARFs regulate the expression of target genes by binding the auxin response elements, TGTCTC, GAGACA [29, 34, 35], or TGTCT [26] that are present in target promoters. These elements have numerous potential combinations with ARFs [4, 19, 30], ...
Migration and mutation
... [4] Class [3] refers to migration of individual genes rather than pairs of genes, as expected if migration involves diploid individuals. Our first paper [5], which I wrote, with migration from the mainland into a single island population, ignores this complication. I have to admit that I entirely fo ...
... [4] Class [3] refers to migration of individual genes rather than pairs of genes, as expected if migration involves diploid individuals. Our first paper [5], which I wrote, with migration from the mainland into a single island population, ignores this complication. I have to admit that I entirely fo ...
PDF - Blood Journal
... obvious phenotype.28 Further testing may reveal abnormalities in these mutant mice, analogous to many microRNAs, in which in vivo loss-of-function phenotypes are only apparent under specific stresses. Understanding the functions of lncRNAs is also complicated by their interesting and unusual evolutio ...
... obvious phenotype.28 Further testing may reveal abnormalities in these mutant mice, analogous to many microRNAs, in which in vivo loss-of-function phenotypes are only apparent under specific stresses. Understanding the functions of lncRNAs is also complicated by their interesting and unusual evolutio ...
1: Summary and Options
... they limit human studies, so the results from animal experiments, using current methods, detect only a small proportion of the kinds and numbers of mutations that can occur. Recent advances in molecular biology have led to the development of new technologies for examining DNA that may provide insigh ...
... they limit human studies, so the results from animal experiments, using current methods, detect only a small proportion of the kinds and numbers of mutations that can occur. Recent advances in molecular biology have led to the development of new technologies for examining DNA that may provide insigh ...
No Slide Title
... The genes having lowest correlation with the “super gene” is removed (shaved). The process is continued until the subset of genes contains only one gene. This process produces a sequence of gene blocks, each containing genes that are similar to one another and displaying large variance across sample ...
... The genes having lowest correlation with the “super gene” is removed (shaved). The process is continued until the subset of genes contains only one gene. This process produces a sequence of gene blocks, each containing genes that are similar to one another and displaying large variance across sample ...
A Unified Statistical Framework for RNA Sequence Data from
... e that are priorly known to be nonother words, there are several rows of A zero at only one column. This is equivalent to the separability assumption introduced by Donoho and Stodden (2003) for the uniqueness of NMF. Unfortunately, marker genes are rarely known in practice. In fact, extracting high- ...
... e that are priorly known to be nonother words, there are several rows of A zero at only one column. This is equivalent to the separability assumption introduced by Donoho and Stodden (2003) for the uniqueness of NMF. Unfortunately, marker genes are rarely known in practice. In fact, extracting high- ...
Nematode genome evolution
... 3. The evolution of chromosome number and structure 3.1. The range of haploid chromosome numbers among nematodes Most nematodes have haploid chromosome numbers of n=4–12 (Walton, 1959). The karyotypes of just ~300 species have been studied, but nematodes display a lot of karyotypic variation (Špakul ...
... 3. The evolution of chromosome number and structure 3.1. The range of haploid chromosome numbers among nematodes Most nematodes have haploid chromosome numbers of n=4–12 (Walton, 1959). The karyotypes of just ~300 species have been studied, but nematodes display a lot of karyotypic variation (Špakul ...
Meiosis II - Solon City Schools
... • http://www.biology.arizona.edu/CELL_BIO/tut orials/meiosis/page3.html ...
... • http://www.biology.arizona.edu/CELL_BIO/tut orials/meiosis/page3.html ...
Lecture Notes in Population Genetics
... In humans, 22 of the 23 chromosome pairs are composed of two chromosomes that are more-or-less the same size and have the same genetic loci. These are called autosomal loci. The remaining chromosome pair has two different types of chromosomes, one (type X) about six times the size of the other (type ...
... In humans, 22 of the 23 chromosome pairs are composed of two chromosomes that are more-or-less the same size and have the same genetic loci. These are called autosomal loci. The remaining chromosome pair has two different types of chromosomes, one (type X) about six times the size of the other (type ...
Ectopic segmentation gene expression and
... absence of the even-numbered en stripes, i.e. misestablishment of the initial embryonic metameres (Ingham & Martinez-Arias, 1986). fn heat-shocked HSF embryos, all en stripes are initiated but alternate domains become unstable (Ish-Horowicz et al. 1988). This appears to be due to the repression of a ...
... absence of the even-numbered en stripes, i.e. misestablishment of the initial embryonic metameres (Ingham & Martinez-Arias, 1986). fn heat-shocked HSF embryos, all en stripes are initiated but alternate domains become unstable (Ish-Horowicz et al. 1988). This appears to be due to the repression of a ...
Genetic testinG
... any of the symptoms or features, then whole genome sequencing can be performed. This test will sequence all 3 billion base pairs in the human genome. It also requires DNA to be extracted, preferably through a blood draw. This test is typically only available on a research basis at this time, given t ...
... any of the symptoms or features, then whole genome sequencing can be performed. This test will sequence all 3 billion base pairs in the human genome. It also requires DNA to be extracted, preferably through a blood draw. This test is typically only available on a research basis at this time, given t ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse