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Parts of a Cell
Parts of a Cell

... strand of DNA • location of genes • humans have 2 of every chromosome (23 pairs, 46 chromosomes) ...
Regulation of Gene Expression
Regulation of Gene Expression

... Eukaryotic genes also are regulated in units of protein-coding sequences and adjacent controlling sites, but operons are not known to occur. ...
DNA, RNA, Genes, Chromosomes
DNA, RNA, Genes, Chromosomes

... It is estimated that humans have 100,000 genes. A flaw in virtually any one of them can result in disease. Each gene acts as a blueprint for making a specific enzyme or other protein. However, only certain genes in a cell are active at any given moment and, as cells mature, many of their genes becom ...
Pathway/Genome Navigator
Pathway/Genome Navigator

... regulated by ArcA.  Highlight all reactions in EcoCyc that are inhibited by ADP. ...
Document
Document

... • Gray flies with vestigal wings and black flies with normal wings are much harder to breed than the ones in b. ...
Honors Biology Final Outline
Honors Biology Final Outline

...  The central dogma for biological information: DNA, RNA, & Protein  The DNA of a gene serves as a template for transcribing this information into RNA (base pairing)  RNA must first be processed (introns, exons) in eukaryotes before a mRNA can be formed o generates transcript diversity  RNA struc ...
Profil N° (à remplir par VAS) FINANCEMENT
Profil N° (à remplir par VAS) FINANCEMENT

... study IQUB, a new Cancer/Testis gene (CT gene). These genes are a key element of methods that involve a patient’s immune system. IQUB is de-repressed in in all somatic cancers that we analyzed using GeneChip expression data from a very large cancer study published by a US consortium. Moreover, mutat ...
Promoter Analysis
Promoter Analysis

... • Frequently the effect of DNA-binding proteins depends on co-factors • E.g. ER sits on the DNA but requires estrogen as a co-factor to function • Myc requires Max as a cofactor to stimulate transcription • If Max is coupled with Mad instead, the genes are repressed ...
Gene linkage and Gene maps
Gene linkage and Gene maps

... Gene linkage and Gene maps Objectives: identify the structures that actually assort independently explain how gene maps are produced the # of genes in a cell is FAR greater than the # of chromosomes each chromosome has hundreds – thousands of genes genes located on the same chromosome that tend to b ...
Medical Symposium
Medical Symposium

...  We get all of our traits from all the generations before us.  Naturally, we each have our own probability of something in our body not working as it should the second we are born.  These include diseases we can get, to small things like poor sight. ...
Methods S1.
Methods S1.

... combines the contribution (covariance, Cov(Tp, X)) and the reliability (correlation, Cor(Tp, X)) in one score plot for interpretation of the predictive component. The SUS-plot that combines the Cor(Tp, X) profiles from two models where classes were compared to a common reference (group A) was used t ...
Section 6-1
Section 6-1

... • Traits controlled by single genes with only two alleles – Height in pea plants – Widow’s peak – Stuff from last unit • Multiple Alleles – Some traits controlled by a single gene with more than two alleles • Blood type – controlled by three alleles – Type A – IAIA or IAi – Type B – IBIB or IBi – Ty ...
BioXpress
BioXpress

... 4. Abstracts are read to identify potential true positive articles. All such articles are downloaded and read to extract key information such as cancer type and expression information. 5. All cancer types are then mapped to Disease Ontology terms and added to the BioXpress database. III. Manual cura ...
Dr. Chris Eskiw Dept. of Food and Bioproduct Sciences University of Saskatchewan
Dr. Chris Eskiw Dept. of Food and Bioproduct Sciences University of Saskatchewan

... The completion of the Human Genome Project was expected to answer many of the questions regarding what we are and how we function at the molecular level. Although this project did provide very useful and insightful information, the primary sequence of our genome is just the first level regulating fu ...
Module 5 revised
Module 5 revised

...  the principle that, among the range of inherited trait variations, those that lead to increased reproduction and survival will most likely be passed on to succeeding generations ...
Lesson 16.1 Genes and Variation
Lesson 16.1 Genes and Variation

... 2. Gene shuffling: a) Independent assortment ____________________________________ b)Crossing over ___________________________________________ c) Random fertilization (through sexual __________________________ ___________________________________________________________ _______________________________ ...
Talk2.stat.methods
Talk2.stat.methods

... Advantages of KNN approach Simple, performs as well as or better than more complex methods  Free from assumptions such as normality of the distribution of expression levels  Multivariate: takes account of dependence in expression levels  Accommodates or even identifies distinct subtypes within a ...
Gen660_Lecture9B_GeneExpressionEvo_2014
Gen660_Lecture9B_GeneExpressionEvo_2014

... Which type of change is ‘more important’ in evolution? Are some genes/processes/functions more likely to evolve by one or the other? What are the features that dictate coding vs. noncoding evolution? ...
Genetic nomenclature for Trypanosoma and Leishmania
Genetic nomenclature for Trypanosoma and Leishmania

... within tandem arrays pose a problem, especially as copy numbers may vary between strains and even between chromosome homologues. If numbering becomes essential a solution may be to use the cross-hatch symbol c , e.g. SLRNAc 3 for the third gene in the array. Nomenclature to distinguish the multiple ...
Genetics and Heredity
Genetics and Heredity

... Co-dominance: in the heterozygous genotype, two alleles are visible in the phenotype at the same ...
Heredity Lecture -Epistasis, Polygenic and Sex
Heredity Lecture -Epistasis, Polygenic and Sex

Identification of Mucin 2 as a Strong Promoter for Gut
Identification of Mucin 2 as a Strong Promoter for Gut

... As per capita consumption of poultry continues to increase, it is necessary for the poultry industry to optimize production to accommodate the growing demand. Discovery of gut-specific genes could significantly improve poultry production. In the present study, the mucin 2 promoter is used to drive o ...
Bacteria Notes File
Bacteria Notes File

... prophage excises from the bacterial chromosome and carries with it some host genes adjacent to the excision site. Also know as restricted transduction. (1) carried out only by _____________________ - phages in the lysogenic cycle. (2) Differs from general transduction in that: –host genes and phage ...
Slide 1
Slide 1

... Some individuals have been found with an XX genotype, but a MALE phenotype. What could account for this? Think-Pair-Share ...
Pierce5e_ch22_lecturePPT
Pierce5e_ch22_lecturePPT

... • Segmentation genes: control the differentiation of the embryo into individual segments • Gap genes: broad region gap differentiation −Hunchback • Pair-rule genes: affect alternate segments • Segment-polarity genes: development of individual segments ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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