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Orthology, paralogy and GO annotation
Orthology, paralogy and GO annotation

... • Practical considerations for RefGenome ...
Darwinian Reductionism and Genocentrism
Darwinian Reductionism and Genocentrism

... The notion of the gene is itself problematic. The idea that there is a single univocal notion of the gene, and that it allows them to be distinguished, individuated, counted, and otherwise treated as the relevant units of hereditary transmission and developmental control, is mistaken. The complexiti ...
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Document

... custom images of the physical or genetic positions of specified sets of genes in one or more genomes or parts of genomes. The positions of user-selected sets of genes are displayed along the chromosomes based on either physical or genetic distances. Multiple sets of genes can be shown simultaneously ...
Lecture 6
Lecture 6

... – How would you test your hypothesis? ...
Lesson 2- environmental inheritance and dominant recessive alleles
Lesson 2- environmental inheritance and dominant recessive alleles

... VARIATION Examples include: - Language spoken - Religion - Hair length - Weight - Piercings - Tattoos ...
ALK Gene Rearrangement: the Evaluation of a New Strategy
ALK Gene Rearrangement: the Evaluation of a New Strategy

Neanderthals in Tibet
Neanderthals in Tibet

... The EPAS1 gene encodes a half of a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall (hypoxia). From Wikipedia ...
Exam301ANS
Exam301ANS

... 1. The addition of a poly T sequence at the 5' end of the gene and the addition of a poly U tail at the 3' end. 2. Addition of a poly A sequence at the 5' end and the addition of a "cap" at the 3' end of the RNA transcript. 3. The addition of a cap at the 5' end of the transcript and the addition o ...
Gene Regulation - public.iastate.edu
Gene Regulation - public.iastate.edu

... Gene Expression DNA Î RNA Î Protein Differentiation requires control ‹All cells in an organism have the same genes ...
Structure and Sequence of the Human Sulphamidase Gene
Structure and Sequence of the Human Sulphamidase Gene

... intron-exon boundaries. These partial sequence data are sufficient to allow definition of mutations in Sanfilippo syndrome patients from genomic DNA and to explore diagnostically useful polymorphisms in this region. The cDNA clone that contained the full coding sequence of sulphamidase, ANS6,4 was u ...
non-mendelian genetics
non-mendelian genetics

... • (Very few genes are found on the Y Chromosome) • Only females can be carriers for sex-linked disorders on the X. ...
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Cabbage(Brassica oleracea L

... tumefaciens-mediated transformation,. In trypsin inhibitor or chitinase activity assay, we found that both sporamin and chitinase activity can be increasing 1-2 times at 2 hrs after wounding. In bioassay, we found that transgenic line 4 is more effectivel to defend Diamond-back moth(Plutella xyloste ...
Divergent evolution: Same basic structure, different appearance
Divergent evolution: Same basic structure, different appearance

... · Allopatric: Physical barrier, isolation can be rapid, influenced by differences in environments · Sympatric: Same country, separated by intrinsic factors, populations evolve separately within range of parent species/same environment, behavioural differences Hardy-Weinberg Principle: · Phenotypic f ...
Principle of Dominance
Principle of Dominance

... alleles segregate from each other so that each gamete carries only a ______ single copy of each gene ____. ...
Chapter 11
Chapter 11

... – Dolly the sheep was the first cloned mammal – Endangered animals that were cloned include cows, oxen, sheep, wildcats, and wolves ...
DNA Subway - iPlant Pods
DNA Subway - iPlant Pods

... • Gene prediction programs search for patterns to predict genes and their structure. • Different gene prediction programs may predict different genes and/or structures. ...
HIT*nDRIVE: Multi-driver Gene Prioritization Based on Hitting Time
HIT*nDRIVE: Multi-driver Gene Prioritization Based on Hitting Time

... Adoption of Cancer Gene Census DB (CGC) and Catalogue of Somatic Mutation Cancer (COSMIC) ...
ANSWERS TO REVIEW QUESTIONS
ANSWERS TO REVIEW QUESTIONS

... Codominance introduces a third phenotype for a gene with two alleles. Epistasis eliminates a progeny class when a gene masks another's expression. Incomplete penetrance produces a phenotype that does not reveal the genotype. Variable expressivity can make the same genotype appear to different degree ...
Thomas Hunt Morgan, 1933
Thomas Hunt Morgan, 1933

... Sturtevant took home some of Morgan’s breeding records. Reasoning that the closer genes are on the chromosome the less likely they are to cross over with the homologous chromosome, he worked all night and the next morning presented Morgan with a linear arrangement of the genes on the X chromosome. S ...
ללא כותרת שקופית
ללא כותרת שקופית

... Highly conserved DNA sequence that encodes ~130 aa• First identified in Drosophila• Encode DNA binding proteins• 8 Pax genes identified in mice and humans• Mutations in Pax1 cause vertebral malformations in mice• Mutations in Pax3 cause pigmentary abnormalities in mice• Mutations in Pax6 cause small ...
BIOLOGY TEST Senior 5 TEAM B Name
BIOLOGY TEST Senior 5 TEAM B Name

... C Mutagens can cause mutations whereas carcinogens can cause cancer. This means that all mutagens are carcinogenic. D Some of the roles of mitosis are growth, asexual reproduction, cell repair following tissue ...
Lecture 1/3/2006
Lecture 1/3/2006

... • Actual measurements (sample) are used to calculate sample-parameters that are used as estimates of population parameters • Example: if we have n replicated microarray experiment, the average of observed log-ratios can be used to estimate the underlying population mean ...
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... C17. A tetrad contains four spores; an octad contains eight. In a tetrad, meiosis produces four spores. In an octad, meiosis produces four cells, and then they all go through mitosis to double the number to eight cells. C18. In an unordered ascus, the products of meiosis are free to move around. In ...
C1. Genetic recombination is a term that refers to a new combination
C1. Genetic recombination is a term that refers to a new combination

... C17. A tetrad contains four spores; an octad contains eight. In a tetrad, meiosis produces four spores. In an octad, meiosis produces four cells, and then they all go through mitosis to double the number to eight cells. C18. In an unordered ascus, the products of meiosis are free to move around. In ...
GenomePixelizer—a visualization program for comparative
GenomePixelizer—a visualization program for comparative

... and incorporated into Web pages. Images may also be saved as a PostScript file and then transformed into GIF or PNG file format. ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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