Lektion 12: Bio- og beregningsteknologi
... Methods of gene transfer • Micro injection of DNA in male pronucleus • Embryonic stemcells and homologue recombination • Micro injection or other forms of gene transfer into foetal cells ...
... Methods of gene transfer • Micro injection of DNA in male pronucleus • Embryonic stemcells and homologue recombination • Micro injection or other forms of gene transfer into foetal cells ...
Improved glutathione production by gene expression in
... Glutathione (GSH, or L - γ -glutamyl-L-γ -cysteinylglycine) exists widely in nature and protects cells againstoxidation (Meister 1994). Its antioxidation function is mainly due to its role in maintaining the normal redox environment of cells (Izawa et al. 1995). GSH is now widely used in pharmaceut ...
... Glutathione (GSH, or L - γ -glutamyl-L-γ -cysteinylglycine) exists widely in nature and protects cells againstoxidation (Meister 1994). Its antioxidation function is mainly due to its role in maintaining the normal redox environment of cells (Izawa et al. 1995). GSH is now widely used in pharmaceut ...
Genetic Engineering
... A possible reason why humans have such a small number of genes as opposed to what was anticipated by scientists is thatA) humans don't need more than 25,000 genes to function.B) the exons used to make a specific mRNA can be rearranged to form genes for new proteins.C) the sample size used to sequenc ...
... A possible reason why humans have such a small number of genes as opposed to what was anticipated by scientists is thatA) humans don't need more than 25,000 genes to function.B) the exons used to make a specific mRNA can be rearranged to form genes for new proteins.C) the sample size used to sequenc ...
QUANTITATIVE INHERITANCE
... Since it is not possible to "count" the number of classes in an F2 population when environmental effects smooth away the genotypic differences, or to identify individuals in the extremes, the number of genes that contribute to the trait cannot be simply estimated. Partitioning sources of variation; ...
... Since it is not possible to "count" the number of classes in an F2 population when environmental effects smooth away the genotypic differences, or to identify individuals in the extremes, the number of genes that contribute to the trait cannot be simply estimated. Partitioning sources of variation; ...
X-linked Alleles
... Colorblindness (1 in 10 males, 1 in 100 females) •Controlled by three genes on X chromosome •In males, a defect in any one of them produces red-green colorblindness •Women are much less likely to have red-green colorblindness because they have two copies of each gene, two chances to get it right. M ...
... Colorblindness (1 in 10 males, 1 in 100 females) •Controlled by three genes on X chromosome •In males, a defect in any one of them produces red-green colorblindness •Women are much less likely to have red-green colorblindness because they have two copies of each gene, two chances to get it right. M ...
SUZ12 antibody - middle region (ARP32515_P050)
... and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer.This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma ...
... and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer.This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma ...
Mendelian Genetics
... • Genome- The complete set of all chromosomes • Genetics- The study of heredity • Gene – A piece of DNA that controls the synthesis of a specific protein • Trait – expression of a gene: i.e. a purple flower, determined by DNA • Dominant trait - expressed over recessive trait when both are present • ...
... • Genome- The complete set of all chromosomes • Genetics- The study of heredity • Gene – A piece of DNA that controls the synthesis of a specific protein • Trait – expression of a gene: i.e. a purple flower, determined by DNA • Dominant trait - expressed over recessive trait when both are present • ...
Quiz 6-KEY
... Part 1- Circle the single best answer for the following questions. 1. We now know that two of the genes Mendel studied, that for flower color and that for seed color, are both located on chromosome 1. Yet Mendel’s results suggested that these two genes were inherited independently of one another. Th ...
... Part 1- Circle the single best answer for the following questions. 1. We now know that two of the genes Mendel studied, that for flower color and that for seed color, are both located on chromosome 1. Yet Mendel’s results suggested that these two genes were inherited independently of one another. Th ...
2_16S_TREE_RECONSTRUCTION
... To perform cladistic analyses we should first align al sequences in order to recognize all homologous positions. ...
... To perform cladistic analyses we should first align al sequences in order to recognize all homologous positions. ...
Diapositiva 1
... biggest difference between mitochondria and other sub-units. mtDNA is only inherited from the mother and exhibits higher mutation rate than that of nuclear DNA as well as low repair capacity. Mitochondrial diseases have threshold effects. That means mitochondrial diseases could occur only if the abn ...
... biggest difference between mitochondria and other sub-units. mtDNA is only inherited from the mother and exhibits higher mutation rate than that of nuclear DNA as well as low repair capacity. Mitochondrial diseases have threshold effects. That means mitochondrial diseases could occur only if the abn ...
Lecture_9_2005
... for replication origins. • Used known replication initiation factors to perform ChIP/chip analysis • Identified hundreds of additional replication origins in a single experiment. ...
... for replication origins. • Used known replication initiation factors to perform ChIP/chip analysis • Identified hundreds of additional replication origins in a single experiment. ...
Presentation - people.vcu.edu
... Results in a single ORF integrated into the host genome 6 of them (protein 7, 8, 14, 15, 18, and 30) were found to have a phenotypic impact on host bacteria Repeated in both E. coli MG1655 and P. aeruginosa PA14 to verify the accuracy of results in P. aeruginosa PAO1 Moved on to Yeast two-hybrid ...
... Results in a single ORF integrated into the host genome 6 of them (protein 7, 8, 14, 15, 18, and 30) were found to have a phenotypic impact on host bacteria Repeated in both E. coli MG1655 and P. aeruginosa PA14 to verify the accuracy of results in P. aeruginosa PAO1 Moved on to Yeast two-hybrid ...
Sex Chromosomes and Male Functions
... obvious: genes with male germline function would be enriched in autosomes after sufficient evolutionary time. This prediction is well corroborated by Drosophila expression analysis using DNA microarray technology26,28 and for many individual genes.17,25-28 Male germline genes also show a strong pref ...
... obvious: genes with male germline function would be enriched in autosomes after sufficient evolutionary time. This prediction is well corroborated by Drosophila expression analysis using DNA microarray technology26,28 and for many individual genes.17,25-28 Male germline genes also show a strong pref ...
Population Genetics
... has reduced the fraction from 25% to 11% in one generation. It would further reduce the fraction each generation, but since there are fewer of them, fewer would be selected against, as well. N.B. natural selection - acts on phenotypes - selects only among variants present Natural selection acts on p ...
... has reduced the fraction from 25% to 11% in one generation. It would further reduce the fraction each generation, but since there are fewer of them, fewer would be selected against, as well. N.B. natural selection - acts on phenotypes - selects only among variants present Natural selection acts on p ...
Population genetics and microevolution
... 3. There is no mutation. If one A mutated to a per 100 alleles, then what was 50% A in the starting population would become 49%A after mutation. Actual mutation rates are about 1/106 per gene, but that translates to about 1 mutation per gamete for us. We are, thus, each unique. ...
... 3. There is no mutation. If one A mutated to a per 100 alleles, then what was 50% A in the starting population would become 49%A after mutation. Actual mutation rates are about 1/106 per gene, but that translates to about 1 mutation per gamete for us. We are, thus, each unique. ...
sequencing all mRNAs
... – Sequencing errors exist, as well as RNA editing – Some species have very few known mRNAs ...
... – Sequencing errors exist, as well as RNA editing – Some species have very few known mRNAs ...
Figures from Chapter 3
... • What we do today was adaptive for ancestors • Example: mothers invest more in child rearing ...
... • What we do today was adaptive for ancestors • Example: mothers invest more in child rearing ...
Cell Evolution in Fast Motion - Max-Planck
... understanding of genetic homogeneity within a species and within an organism. When one considers, for example, that a tobacco leaf comprises significantly more than five million cells, it becomes clear that the cells in one and the same leaf on a plant are not necessarily geneti- ...
... understanding of genetic homogeneity within a species and within an organism. When one considers, for example, that a tobacco leaf comprises significantly more than five million cells, it becomes clear that the cells in one and the same leaf on a plant are not necessarily geneti- ...
12-1 Chromosomes and Inheritance patterns
... • Offer an explanation for why morgan did not find white-eyed female drosophilia in the F2 generation when he crossed white eyed males with red eyed females. • The eye color gene is located on the X chromosome and any female offspring would be heterozygotes ...
... • Offer an explanation for why morgan did not find white-eyed female drosophilia in the F2 generation when he crossed white eyed males with red eyed females. • The eye color gene is located on the X chromosome and any female offspring would be heterozygotes ...
+ - + - + CsgD
... Cyclic-di-GMP is a “fashionable” second messenger in bacteria • Originally identified as allosteric inducer of cellulose biosynthesis in G. xylinum • Involved in exopolysaccharide production in many bacteria • Cell cycle and differentiation in C. ...
... Cyclic-di-GMP is a “fashionable” second messenger in bacteria • Originally identified as allosteric inducer of cellulose biosynthesis in G. xylinum • Involved in exopolysaccharide production in many bacteria • Cell cycle and differentiation in C. ...
Gene expression profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.