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AP Biology: Unit 3B Homework
AP Biology: Unit 3B Homework

... 11. Describe the ways in which repetitive DNA can occur. 12. What is a multigene family? 13. Finish the sentence: “Multigene families are hypothesized to have evolved from …” 14. What is the function of the globin multigene family in humans? 15. Describe how duplication of an entire chromosome set c ...
Mendelian Genetics
Mendelian Genetics

... expressed in most heterozygous organisms. • Tt, Aa, Rr ...
Patterns of Inheritance Worksheet #5
Patterns of Inheritance Worksheet #5

... acids. In many cases, the dominant allele codes for a polypeptide that works, whereas the recessive allele codes for a polypeptide that does not work. For example, suppose that the allele B codes for an enzyme that makes a black pigment in a mouse’s fur and allele b codes for a defective enzyme that ...
Affymetrix Data analysis
Affymetrix Data analysis

... Now we are ready to examine the selected genes for differential expression between the BCR/ABL samples and the cytogenetically normal ones. 4.1. Use the two–sample t–test to identify genes that are differentially expressed between the two groups. The function mt.teststat from the multtest package al ...
The Good, the bad and the ugly of Genetic Engineering
The Good, the bad and the ugly of Genetic Engineering

... What it did do: Tell us each an every nucleotide of the human genome (all 3.2 billion) What it did not do: Tell us what it all means!!! ...
Genomics and Behavior “Central Dogma” Outline
Genomics and Behavior “Central Dogma” Outline

... • Can identify splice variants – Some genes like brain derived neurotrophic factor have many splice variants ...
AP Biology Review Unit 5 and 6
AP Biology Review Unit 5 and 6

... 2 Testosterone binds to a receptor protein in the cytoplasm, activating it. ...
Zoo/Bot 3333
Zoo/Bot 3333

... heterozygotes "uncovered" (see p. 496/3e; p. 435/4e in text) these recessive mutations and allowed them to show pseudodominance, indicated by a minus sign in the table: ...
A BIT ON DROSOPHILA GENETICS AND NOMENCLATURE
A BIT ON DROSOPHILA GENETICS AND NOMENCLATURE

... Complementation analysis is one of the most simple and yet extremely informative tools in a geneticist’s arsenal. The analysis is used when you wish to find out if two separate mutations occur in the same gene or different ones. Complementation analysis is based on the mendelian concept of one gene ...
Library screening
Library screening

... The cDNA library is then plated at a relatively low density to facilitate subsequent identification of individual clones by colonies or plaques hybridization Two replica filters are taken from the master plate and hybridized independently to labeled probes obtained by reverse transcription of the mR ...
Glossary Adaptability, evolvability or adaptive potential: the ability of
Glossary Adaptability, evolvability or adaptive potential: the ability of

... and seed movement which can reach considerable distances. It is one of the major processes that affects (usually increases) the genetic diversity of a population. Gene: a segment of DNA carrying heritable genetic information. A locus (plural loci) can refer to a gene, a part of it or to non-genic DN ...
Document
Document

...  Alterations of chromosome number and structure are associated with some serious disorders  Some types of aneuploidy appear to upset the genetic balance less than others, resulting in individuals surviving to birth and beyond  These surviving individuals have a set of symptoms, or syndrome, chara ...
Gene-linkage and Karyotype
Gene-linkage and Karyotype

... INTRODUCTION TO LINKED GENES AND SEX LINKAGE H. Biology/ Ms. Kim ...
Gene Duplication
Gene Duplication

... Pigments are proteins that are sensitive to certain wavelengths (colors) of light. Your retina contains four different light-sensitive pigments (rhodopsin, blue, red, and green pigments). The gene that codes for rhodopsin is the original eye-pigment gene. It is found on chromosome #4. All the other ...
April 3 lecture slides
April 3 lecture slides

... promoter and the interactions between them ...
Genes and Genetic Disease
Genes and Genetic Disease

...  Homozygous – loci on a pair of chromosomes have identical genes Example: O blood type (OO)  Heterozygous – loci on a pair of chromosomes have different genes Example: AB blood type (A & B genes on a pair of loci) ...
Paroxysmal movement disorders
Paroxysmal movement disorders

... -Age of onset: Mean 5 years, range 6 months to 35 years (RARE to have onset > age 18) -Trigger: NOT movement; classically alcohol, caffeine, or strong emotion/stress that elicits the abnormal movement, though sometimes may have no clear trigger at all. -Aura: Sometimes present. Tightness in a limb, ...
Exercise 2 — Zebrafish
Exercise 2 — Zebrafish

... dbSNP and literature? (http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs=1801133) (d) What is the major allele in rs1801133? (e) In which paper(s) is the association between rs1801133 and homocysteine levels described? (f) According to the data imported from dbSNP, the ancestral allele for rs1 ...
Evidence for the design of life: part 1—genetic redundancy
Evidence for the design of life: part 1—genetic redundancy

... systems. It is ironic that standard wall charts of biochemical reactions show hundreds of coupled reactions working together in networks, while graduate students are tacitly encouraged to think in terms of linear cause and effect. The linear cause-and-effect thinking in ancient Greek philosophy ...
Evidence for the design of life: part 1—genetic redundancy
Evidence for the design of life: part 1—genetic redundancy

... systems. It is ironic that standard wall charts of biochemical reactions show hundreds of coupled reactions working together in networks, while graduate students are tacitly encouraged to think in terms of linear cause and effect. The linear cause-and-effect thinking in ancient Greek philosophy ...
Genetics of Cancer
Genetics of Cancer

... Tumour Suppressor Genes- are genes that act to inhibit cell proliferation and tumour development. Mutation or inactivation of the tumour suppressor gene will cause cancer or cell transformation.  RB gene is a tumor suppresser protein  The retinoblastoma protein (abbreviated pRb, RB or RB1) is a tu ...
Chapter 7.3-7.4
Chapter 7.3-7.4

... 11. How does genetic inheritance follow similar patterns in all sexually reproducing organisms? ___________________________________________________________________________________________ ___________________________________________________________________________________________ 12. Who can be carr ...
Designer Babies & the government
Designer Babies & the government

... what body type they will have their hair and eye color what sorts of illnesses they will be naturally resistant to and even, conceivably, their IQ and personality type. ...
Brooker Chapter 5
Brooker Chapter 5

... • In diploid eukaryotic species, linkage can be altered during meiosis as a result of crossing over • Crossing over – Occurs during prophase I of meiosis at the bivalent stage – Non-sister chromatids of homologous chromosomes exchange DNA segments ...
Mosaic Analysis
Mosaic Analysis

... basis of charge and molecular weight Mass spectrometry for identifying proteins by measuring the mass-to-charge ratio of their ionized ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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