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Review 1 - LFHS AP Biology
Review 1 - LFHS AP Biology

... 13. If two heterozygotes for tall (T) and green (G) are crossed, what fraction of the offspring are likely to be short and purple (both recessive, and assume no linkage). ...
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Leukaemia Section t(3;9)(q27;p24) Atlas of Genetics and Cytogenetics in Oncology and Haematology

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... time. Currently, a great deal of effort is going into the testing of this model by measuring the deleterious mutation rate, in a range of organisms from yeast to mouse. But the answer is still not entirely clear. Enter the Red Queen In the late 1980s the Red Queen hypothesis emerged, and it has been ...
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... Correlation networks are a useful tool in identifying trends in large biological data sets. In particular correlation networks have been used extensively to study gene co-expression; the process by which genes are expressed in coordination to produce proteins. Here we construct and analyse the gene ...
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... •  Molecular analysis of the homeotic genes in Drosophila has shown that they all include a sequence called a homeobox •  An identical or very similar nucleotide sequence has been discovered in the homeotic genes of both vertebrates and invertebrates •  Homeobox genes code for a domain that allows a ...
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... Heritability estimates are often made by comparing the extent of phenotype similarity in identical twins raised together versus those adopted and raised apart. For example, studies like these suggest that about 40% of the population variability in shyness can be explained in terms of genetic differe ...
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分子生物学(Molecular Biology) CAI教程

... Traits controlled by gene ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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