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Web API In addition to the web interface, one can access Cas
Web API In addition to the web interface, one can access Cas

... {"page_count": 1, "offtargets": [{"chromosome": "chr2", "sequence": "GCATGACAAAAgATaAGACAGGG", "region": "Intergenic", "strand": "+", "position": 126565746, "mismatch_count": 2}, {"chromosome": "chr3", "sequence": "tCATGACAAAAAATCAGAaACAG", "region": "Intergenic", "strand": "+", "position": 16399127 ...
Genetics
Genetics

... • Two alleles are necessary for a trait • The genes are symbolized by the first letter of the dominant gene. • The letter for the dominant gene is always capitalized. • The letter for the recessive trait is always lower case (make sure you can tell the difference between the two) • Wild Type is the ...
Lecture#16 Page 1 BIOLOGY 207
Lecture#16 Page 1 BIOLOGY 207

... Round, Yellow Round, green wrinkled, Yellow ...
De novo assembled expressed gene catalog of a
De novo assembled expressed gene catalog of a

... exclude low quality and ribosomal RNA-derived reads. Supplemental Table S2. The complete gene catalog from Arabidopsis thaliana (TAIR 9) was used to query the EucALL dataset and the Velvet assembled dataset containing 18,894 contigs from this study. Significant BLAST hits were counted in incrementin ...
Lecture slides
Lecture slides

Problem Set II Answer Key
Problem Set II Answer Key

... trehalose (glucose only), the operon should be off with the repressor bound. When tre B is absent, the  operon is on, so tre B must be a repressor. A is an activator because in the presence of trehalose only  (no glucose), we would expect high expression of the operon due to activator activity. But  ...
BME435 BIOINFORMATICS
BME435 BIOINFORMATICS

... BIOINFORMATICS involves the technology that uses computers for  Storage,  Retrieval,  Manipulation,  Distribution of information related to biological macromolecules such as DNA, RNA, and proteins. ...
Genetics PowerPoint
Genetics PowerPoint

... In a genetic cross, the combination of alleles that parents can pass to an offspring is based on probability = the mathematical chance that an event will occur Punnett Square (designed by Reginald C. Punnett) a chart that shows all the possible ways alleles can combine in a genetic cross ...
The Genetics of SLE
The Genetics of SLE

... deoxyribonucleic acid, or DNA. Genes act as the cell’s instruction guide for all life-supporting functions. This process in turn determines an individual’s traits and features, such as eye-color or height, as well as day-to-day cellular activities. Humans have an estimated 27,000 genes, over 23 chro ...
142KB - NZQA
142KB - NZQA

... Gene expression – information from one gene is used to synthesise a functional protein / the production of a gene product(protein) using the DNA template and the genetic code / the whole process of transcription and translation – including protein folding and any post-translational modifications. ...
103KB - NZQA
103KB - NZQA

... and its anticodon complementary (H bonding) matches to the codon (3 consecutive bases) on the mRNA strand. The amino acid bonds with another amino acid to produce a polypeptide chain. The cell continually makes mRNA because it’s a (relatively) short-lived molecule; DNA is long-lived. DNA is protecte ...
E. Linked genes
E. Linked genes

... A. only his mother B. only his father C. the mother or father, but not both D. both the mother and the father E. it is impossible to determine with certainly using only the given information 54. Why are traits controlled by sex-linked recessive genes more often expressed in males? A. Males inherit t ...
Chapter 11 - Evangel University
Chapter 11 - Evangel University

... • Elongation is controlled by: • _________ sites, where RNA Pol will hesitate • _________, which proceeds past the normal termination point • _________ _________ _________ _________ (P-TEF) and _________ _________ _________ _________ (N-TEF) ...
CHAPTER 10 STUDY GUIDE (Mendel and Meiosis)
CHAPTER 10 STUDY GUIDE (Mendel and Meiosis)

... 5) Know the reasons why Mendel used Pea plants as a means to study heredity (4). 6) Be able to generate possible parental genotypes from a single genotype. For example, what are the possible genotypes from a parent TtGg? 7) Know how to complete a monohybrid and dihybrid punnett square cross from two ...
Document
Document

... on both transcriptional regulation (TR) and metabolism. In response to external oxygen level, two global regulators, FNR and ArcA, activate or repress a large number of enzymes, which in turn switches on/off certain metabolic pathways. Based on metabolic flux simulations and the known regulatory net ...
File
File

... 18) Mendel was able to draw his ideas of segregation and independent assortment because of the influence of which of the following? A) His reading and discussion of Darwin's Origin of Species B) The understanding of particulate inheritance he learned from renowned scientists of his time C) His disc ...
Powerpoint Slides 6.2 Part B
Powerpoint Slides 6.2 Part B

... If cII builds up fast enough it activates the transcription of cI and also some integration functions. cI is called the lambda repressor. It shuts off all lambda genes except itself and allows lambda DNA to integrate into the host chromosome. ...
biocyc-data-content - Bioinformatics Research Group at SRI
biocyc-data-content - Bioinformatics Research Group at SRI

... • Databases • Genome Browser • Genes, Proteins, Regulation, Reactions, Pathways • Overviews ...
PSet - CS109
PSet - CS109

... • if both of the eye-color genes are blue-eyed genes, then the person will have blue eyes • if one or more of the genes is a brown-eyed gene, then the person will have brown eyes A newborn child independently receives one eye-color gene from each of its parents, and the gene it receives from a paren ...
EcoCyc: Encyclopedia of Escherichia coli genes and metabolism
EcoCyc: Encyclopedia of Escherichia coli genes and metabolism

... can suppress the display of enzyme names or side-compound names; they can also draw chemical structures for the compounds within a pathway. More details on the display algorithms can be found in ref. 5. THE EcoCyc DATA The EcoCyc data are stored within a frame knowledge representation system (FRS) c ...
Investigation of the role of the Inflammasome triggering HIN200
Investigation of the role of the Inflammasome triggering HIN200

... the Slam locus. ANA slides were prepared using Hep2 cells and titres were quantified according to the serial dilutions at which fluorescence in cells converted from positive to negative. Renal H&E sections were graded according to mesangial hypercellularity and matrix increase. Grade 0= no histologi ...
Nobel Laureate 1995
Nobel Laureate 1995

... knowledge of what the genes are made of. Actually, the dogma of the t ime was that they were proteins, but this didn't help, and in fact was completely wrong. " Drosophila genetics had many advantages then, and now, according to Lewis. "There was an immense background of information available as wel ...
Core
Core

... (a) Obtain all the CpG islands on the first 5 Mb of dog chromosome 20. Print the total number of CpG islands and the position and sequence of each CpG island. (b) Obtain all the protein alignment features on the first 5 Mb of dog chromosome 20. Print for each alignment the name of the aligned protei ...
Use it or lose it: molecular evolution of sensory
Use it or lose it: molecular evolution of sensory

... followed by a relaxation of selective pressure on the gene that leads to disruption in the coding sequence; in some cases, duplicated genes were redundant and thus quickly eliminated from the genome, but in other cases they acquired a function only to become obsolete at a later time in evolution. By ...
gaynes school scheme of work b1
gaynes school scheme of work b1

... H: explain the link between the sex-determining gene and the development of sex organs into either ovaries or testes  explain that chromosomes in a pair carry the same genes in the same place  explain that there may be different versions of the genes called alleles  explain that an individual usu ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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