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Meiosis Notes November 14, 2012
Meiosis Notes November 14, 2012

... • When homologous chromosomes are paired together, this is referred to as a tetrad. • Example: Humans have 46 chromosomes or 23 pairs. One set from dad ...
punnet squares, crosses, linked genes and pedigreesppt
punnet squares, crosses, linked genes and pedigreesppt

... A crossing over point is more likely to occur on a chromosome between two genes that are widely separated compared to genes that are closer together ...
Lab #2
Lab #2

... • Neither tests is as sensitive as the T-test, ie they require more data points to detect the same amount of difference, so use the T-test whenever it is valid. • K-S test and WMW can give you different answers: K-S detects difference of distributions, WMW detects difference of medians • Rare proble ...
Evolution of colour vision in primates
Evolution of colour vision in primates

B/B a/a - kcpe-kcse
B/B a/a - kcpe-kcse

... Other example is achondroplasia, the most common form of dwarfism, with a normal length body trunk but shortened limbs. ...
Coeliac tissue typing
Coeliac tissue typing

... Inactivation of the FMR1 (Fragile X Mental Retardation 1) gene leads to Fragile X syndrome, the most common single gene cause of intellectual disability/developmental delay. Fragile X syndrome can include intellectual disability, autistic spectrum disorder and characteristic physical features. Inact ...
Divergent Evolutionary and Expression Patterns between Lineage
Divergent Evolutionary and Expression Patterns between Lineage

... To identify A. thaliana specific new genes, we selected new genes based on two criteria: first, the gene was not located in any of the syntenic regions between A. thaliana and the rest of three species A. lyrata, C. rubella, B. rapa; second, the gene did not have any reciprocal ortholog in A. lyrata ...
Structure, expression differentiation and evolution of duplicated fiber
Structure, expression differentiation and evolution of duplicated fiber

... genes, except Exp1 in the Hai7124 cultivar, to be independently isolated with a single copy from the diploid species and two homeologs from each tetraploid species for each gene. There was a single copy of Exp1 in the diploid species and two distinct copies in TM-1, however, the Exp1 sequence from H ...
Handouts
Handouts

... The  Yoneda  lemma  allows  the  embedding  of  any  category  into  a  category  of  functors  defined   on  that  category.  It  suggests  that  instead  of  studying  the  (small)  category  C,  one  should  study   the  category  o ...
Chapter 7
Chapter 7

... • The lac operon is an inducible operon and contains genes that code for enzymes used in the hydrolysis and metabolism of lactose • By itself, the lac repressor is active and switches the lac operon off • A molecule called an inducer inactivates the repressor to turn the lac operon on ...
Preview Study Guide
Preview Study Guide

... the differences among individuals reflect the combined influences of many genes (in interaction with the environment, of course), not the effects of single genes. 9. Characteristics affected by many different genes are called traits. When we measure differences among individuals in such traits, they ...
Markscheme
Markscheme

Hands-On Activities That Relate Mendelian Genetics To Cell
Hands-On Activities That Relate Mendelian Genetics To Cell

... be heterozygous for that trait.If an individual has two alleles of the same type, for example two alleles for brown eyes, then it is called homozygous. Gregor Mendel, the founder of modern genetics, discovered that alleles separate during meiosis and end up in different gametes. We now call this the ...
The Drosophila Expression System.
The Drosophila Expression System.

... A wide range of proteins have been expressed using DES®. ...
Pedigree Analysis in Human Genetics
Pedigree Analysis in Human Genetics

... •  Pattern of inheritance that results from genes located only on the Y chromosome ...
Evolution by the birth-and-death process in multigene
Evolution by the birth-and-death process in multigene

... the polymorphism include those of maternal–fetal incompatibility, mating preference, overdominant selection, frequencydependent selection due to minority advantage, and interlocus gene conversion. This problem has been discussed by Hughes and Nei several times (15, 16, 30, 31), and we are not going ...
Article The Pseudoautosomal Regions of the U/V Sex
Article The Pseudoautosomal Regions of the U/V Sex

... size (Spearman’s correlation test  = 0.113, P = 0.598) whereas gene density and GC percentage increase with ...
Chapter 6: Extranuclear Inheritance, Imprinting, and Maternal Effect
Chapter 6: Extranuclear Inheritance, Imprinting, and Maternal Effect

... As with chloroplasts, mitochondria have their own genetic material, and their pattern of transmission is non-Mendelian. In this section, we will examine the nature of the mitochondrial genome, and how mitochondria are transmitted from parents to offspring. Note that the genetic material of the mitoc ...
Introduction to pGLO lab
Introduction to pGLO lab

...  Then the bacteria will express the new “foreign” DNA, and the bacteria will perform new functions. ...
Chapter 15~ The Chromosomal Basis of Inheritance
Chapter 15~ The Chromosomal Basis of Inheritance

... X R Xr ...
Slide 1
Slide 1

... • is a member of the TCP family of transcriptional regulators, a class of genes involved in the transcriptional regulation of cell-cycle genes. •Differences in tb1 expression patterns between maize and teosinte indicate that human selection was targeted at regulatory differences that produced a high ...
Posterior uncertainty for rank data aggregation and a priori plans for
Posterior uncertainty for rank data aggregation and a priori plans for

... Prob ( member Nils likes movie A better than movie B? ) Prob ( for member Nils movie A will be among his top 5 preferences ?) MovieLens uses collaborative filtering to generate recommendations. It matches users with similar opinions about movies. Each user has a 'neighbourhood' of other like-minded ...
Gene Conversion in Human Genetic Disease
Gene Conversion in Human Genetic Disease

... 4. Gene Conversion vs Transient Hypermutability: A Mechanistic Comparison Data from a wide variety of organisms (including viruses, prokaryotes and yeast, as well as cell lines and tissues from higher eukaryotes) have clearly demonstrated that the number of instances of multiple mutation is signific ...
Document
Document

... • Ensembl is a joint project between EMBL - European Bioinformatics Institute (EBI) and the Wellcome Trust Sanger Institute (WTSI) to develop a software system which produces and maintains automatic annotation on selected eukaryotic genomes. Ensembl is primarily funded by the Wellcome Trust. • Goals ...
Chapter 15 final
Chapter 15 final

... (EG. Positive or negative blood factor, right or left handed, ear lobe shape, dimpled chin, hand clasp) ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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