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Hybridisation techniques rely on a probe sequence which is
Hybridisation techniques rely on a probe sequence which is

F. nucleatum - California State University, Long Beach
F. nucleatum - California State University, Long Beach

...  The incorporation of Neu5Ac into F. nucleatum LPS can hinder the function of the host defenses via disruption of the complement pathway as has been shown in the case of N. gonorrhoeae, which is resistant to complement activation due to the presence of Neu5Ac in the bacterium LPS.  Siaylation of F ...
A feather in the cap for bird breeders
A feather in the cap for bird breeders

... too often mar the discussion of genetics. Birkhead, for example, explains that species hybrids are especially vigorous because only one gene of each pair is expressed, and that the “genes that are turned on are those that best complement the rest of that individual’s genetic make-up”. But even if hy ...
The Complete Sequence of 340 kb of DNA around the
The Complete Sequence of 340 kb of DNA around the

... A 2.3-centimorgan (cM) segment of rice chromosome 11 consisting of 340 kb of DNA sequence around the alcohol dehydrogenase Adh1 and Adh2 loci was completely sequenced, revealing the presence of 33 putative genes, including several apparently involved in disease resistance. Fourteen of the genes were ...
Gene Section CDK4 (cyclin-dependent kinase 4) Atlas of Genetics and Cytogenetics
Gene Section CDK4 (cyclin-dependent kinase 4) Atlas of Genetics and Cytogenetics

... This work is licensed under a Creative Commons Attribution-Non-commercial-No Derivative Works 2.0 France Licence. © 2007 Atlas of Genetics and Cytogenetics in Oncology and Haematology ...
reviews - UO Blogs
reviews - UO Blogs

... such as neurological disorders, cancer, developmental disorders, metabolic and storage disorders and cardiovascular disease, as well as homologues of genes required for the visual, auditory, and immune systems. This and other bioinformatic analyses indicate that D. melanogaster can serve as a comple ...
Bacterial Gene Regulation
Bacterial Gene Regulation

... genes that perform routine tasks necessary for life • Regulated transcription – expression at particular times  for genes that are differentially required under varied conditions • Regulated transcription includes control of both initiation and amount of transcription • Control is modulated by inte ...
RNA Express Workflow - support.illumina.com
RNA Express Workflow - support.illumina.com

... This document and its contents are proprietary to Illumina, Inc. and its affiliates ("Illumina"), and are intended solely for the contractual use of its customer in connection with the use of the product(s) described herein and for no other purpose. This document and its contents shall not be used ...
Genomic imprinting effects on brain development and function
Genomic imprinting effects on brain development and function

... The unique epigenetic status of imprinted genes has led to several theories as to why they exist. These include ideas that they occur to prevent parthenogenesis99, as a means to give rise to rapid evolution at certain loci100, and to promote the coadaptation of the physiology and behaviour of the mo ...
regional mapping of the gene coding
regional mapping of the gene coding

... The locus for human a subunit ( a j has been mapped to chromosome 1 both by family study (Giblett, Chen, Anderson & Lewis, 1974) and by cell hybrid analysis (Meera Khan, Deppert, Hagemeijer & Westveld, 1974). The locus for human fi subunit (/fj) has been mapped to chromosome 12 using cell hybrids (G ...
Megavirus - Mister Gui
Megavirus - Mister Gui

... disperse to do their different jobs. Instead, they assemble into a “virus factory” that sucks in building blocks and spits out large pieces of future giant viruses. Giant viruses even get infected with their own viruses. People often ask me if I think viruses are alive. If giant viruses aren’t alive ...
complex patterns of inheritance
complex patterns of inheritance

... amount of milk a cow produces, and the number of apples on an apple tree. Consequently, much of our modern understanding of quantitative traits comes from agricultural research. Quantitative traits are polygenic, which means that several or many genes contribute to the outcome of the trait. For many ...
Gene-and-Chromosome-Mutations
Gene-and-Chromosome-Mutations

... • Chromosome mutations are normally large changes which are usually detectable under the microscope during cell division. • They usually occur during crossing over when the number or sequence of genes may be altered. • When a chromosome is broken it has a sticky end which can join onto other chromos ...
The Complete Mitochondrial DNA (mtDNA) of the Donkey and
The Complete Mitochondrial DNA (mtDNA) of the Donkey and

... Between the two whales the difference is 8.7% (eighth ranking position), whereas between Homo and the chimpanzee the difference is 11.9% (13th position). Also among different modes of comparison pronounced differences may occur. Thus the total nt difference in ATPase8 is low, whereas it is very high ...
6. Hair color genetics 2014
6. Hair color genetics 2014

... Chromosomes from 1 human cell ...
RNA Interference Regulates Gene Action
RNA Interference Regulates Gene Action

... sequence of just a portion of the gene to be targeted, the synthesis of the corresponding RNA molecule, and a method to introduce it into cells and organisms. The technical advance of RNAi could not have come at a more opportune time. Large-scale sequencing is now producing vast amounts of genomic d ...
Resources - Real Science
Resources - Real Science

Yeast Chitin Binding Domain Tag | NEB
Yeast Chitin Binding Domain Tag | NEB

... Overview of Protein Secretion in K. lactis ...
"What is a gene, in the post-ENCODE era?"
"What is a gene, in the post-ENCODE era?"

... genome has been shaken by ENCODE The ENCODE consortium recently completed its characterization of 1% of the human genome by various high-throughput experimental and computational techniques designed to characterize functional elements (The ENCODE Project Consortium 2007). This project represents a m ...
Azadeh Hamid Reza
Azadeh Hamid Reza

... Selection response by phenotypic selection would be low because of low heritability of some traits (Rothschild and Bidanel, 1998). MAS can increase the selection response (Larzal et al., 1997) by finding a QTL (Wilkie et al., 1999) or mutations in genes with physiological functions (Andersson and Ge ...
Genetics IV: Biochemical Genetics
Genetics IV: Biochemical Genetics

... -plate mutangenized cells on rich medium -replica plate (transfer) yeast colonies to minimal medium -look for colonies that cannot grow on minimal medium -this is a mutant that has some kind of defect in a biosynthetic pathway -the way you design a mutant hunt will determine what mutants you will fi ...
What constitutes an `alternative TSS`? Example 1: Alternative TSS at
What constitutes an `alternative TSS`? Example 1: Alternative TSS at

... What if the event involves a terminal exon? 1. Long (‘on’) exon? No – APA! ...
Genomic imprinting and the units of adaptation
Genomic imprinting and the units of adaptation

... class kAK ¼ {m,p} according to whether it is maternal or paternal in origin (each individual having one maternally derived gene and one paternally derived gene at the locus of interest). Accordingly, every gene in the population is uniquely identifiable by its carrier’s index i and its own class k. ...
Mining medical data using multiple corpora
Mining medical data using multiple corpora

... developped by INIST/ CNRS and INRIA. It works under the Unix operating system and is composed of two main kinds of tools : first, functions for converting heterogeneous data into SGML/XML trees and for handling such trees or records, and, second, for building information retrieval systems like inves ...
Analysis of Gene expression data using MATLAB Software
Analysis of Gene expression data using MATLAB Software

... one of the most frequently used methods for clustering gene expression profiles. However, commonly used methods for agglomerative hierarchical clustering rely on the setting of some score threshold to distinguish members of a particular cluster from non-members, making the determination of the numbe ...
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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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