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Visualizations of Microarray Data in Partek Genomics Suite 6.6
Visualizations of Microarray Data in Partek Genomics Suite 6.6

... PGS’s function Sort rows by prototype enables you to identify genes with similar expression profiles. For instance, if a gene with an interesting expression pattern has been detected, using Sort by prototype makes it possible to find other genes that have a similar pattern of intensity values. Altho ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008.
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) e-ISSN: 2278-3008.

... based on their sequence and structural similarities they are classified into family 18 and family 19 glycosidases. Family 18 chitinases are structurally different from family 19 chitinases and consist of a highly conserved catalytic motif (DxxDxDWEYP) and are inhibited by allosamidin, a pseudotrisac ...
slides - DTU CBS
slides - DTU CBS

... • My answer: gene claims should have same scope as all other claims – Traditional compound claims cover all uses – Why should gene patent stop development and research while patents in other fields enhance research? – Again: do not confuse patent applications with valid granted claims ...
Chapter 6 - Speedway High School
Chapter 6 - Speedway High School

... KEY CONCEPT Genes encode proteins that produce a diverse range of traits. ...
genetic disorder of haemoglobin
genetic disorder of haemoglobin

... Major abnormalities & problems in SCA Sickling of the red cell during deoxygenation, as the HbS has low solubility at low O2 partial pressure and precipitates.  Chronic haemolytic anaemia due to repeated sickling in tissues and unsickling in the lungs.  Plugging of microcapillaries by rigid sick ...
beckwith-wiedemann syndrome
beckwith-wiedemann syndrome

... 1. Some cases of BWS warrant a cytogenetic analysis to rule out chromosome translocations (seen in <1% of BWS patients) 2. Parental samples are required to confirm paternal UPD in cases where a dosage discrepancy is suspected in the patient. 3. A negative molecular test result does not rule out the ...
Coupling of zygotic transcription to mitotic control at the Drosophila
Coupling of zygotic transcription to mitotic control at the Drosophila

... degradation are coupled through the transcription of specific microRNAs that promote maternal RNA deadenylation and clearance (Giraldez et al., 2006). A similar role for zygotically expressed miRNAs has been postulated for maternal RNA degradation during Drosophila MBT (Bushati et al., 2008). Howeve ...
Accurate and Comprehensive Mapping of Multi-omic Data
Accurate and Comprehensive Mapping of Multi-omic Data

... Pathway analysis provides a useful biological context for differentially expressed entities resulting from the analysis of high-throughput data in any ‘omics’ (for example genomics, transcriptomics, proteomics, or metabolomics) experiment. Pathways overrepresented or enriched in the entities of inte ...
“The Genetics of Depression and Related Traits,” by Patricia Huezo
“The Genetics of Depression and Related Traits,” by Patricia Huezo

... genes, those whose proteins are responsible for the synthesis, transportation, inactivation and degradation of these neurotransmitters are being investigated with the assump on that allelic variants within these genes may affect function and contribute to vulnerability to depression. Several associa ...
It might, however, be useful to Thus  fl^Y
It might, however, be useful to Thus fl^Y

... located the gene for resistance to chromosome V; there were 10 resistant fac^+ and 20 sensitive fac^- haploids, with markers on all other chromosomes segregating independently. Colonies of HU-R2, 3 and 4 had a linear growth rate on CM less than that of wild type, and a modified surface morphology se ...
Document
Document

... o Not just naked DNA, but coded in nucleoprotein material  Nucleoprotein material of the eukaryotic chromosome is called chromatin (complex of DNA, protein and RNA) Slide 7 – EM of a liver cell nucleus  Note the cytoplasm, nucleus & nuclear membrane  Two types of chromatin:  Euchromatin – more a ...
(a) (b)
(a) (b)

... Behavior of a Chromosome Pair • In one experiment, Morgan mated male flies with white eyes (mutant) with female flies with red eyes (wild type) – The F1 generation all had red eyes – The F2 generation showed the 3:1 red:white ...
Recombination and clonal groupings within Helicobacter pylori from
Recombination and clonal groupings within Helicobacter pylori from

Evolution of the vertebrate jaw: comparative embryology and
Evolution of the vertebrate jaw: comparative embryology and

... Dlx and Otx genes The shared developmental features identified between the lamprey and gnathostomes are most likely to represent the ancestral programme possessed by the common ancestor (Fig. 3B; also see Trainor et al. 2003, for a similar method of speculation), whereas there can also be programmes ...
Multiple domestications of Asian rice
Multiple domestications of Asian rice

... Huang and Han1 also contend that the presence of similar haplotypes, including identical coding sequences, in cultivated groups for loci such as sh4 and PROG1 argues against multiple domestication. In our Supplementary Information2 we explained how selection of similar haplotypes that are geographic ...
One vitellogenin gene in an ocean of many: The molecular ecology
One vitellogenin gene in an ocean of many: The molecular ecology

... matches within Alveolata WGS and TSAs. Blast hits of up to 96% identity were found within TSAs for Symbiodinium species, and we suggest that the aqpH1-5 orthologs are likely derived from zooanthellate endosymbiotic dinoflagellates. Similarly, the divergent starlet sea anemone sequence (EDO28361) enc ...
How pupils use a model for abstract concepts in genetics
How pupils use a model for abstract concepts in genetics

... needs hair to keep warm and a bird needs feathers to fly. The relationship between the dog and the hair was not compared with the relationship between the bird and the feathers. Older children of approximately 11 years of age and older were able to consciously explain the hierarchical relation and c ...
Controlling morpholino experiments: don`t stop making antisense
Controlling morpholino experiments: don`t stop making antisense

... genetic screens are of inestimable value in understanding a particular process, they cannot be guaranteed to target the desired gene nor can they be guaranteed to produce a null mutation. Thus, researchers need a way to inhibit the functions of genes. Dominant-negative approaches have their place, b ...
Investigation 9: Genetic Variation
Investigation 9: Genetic Variation

... walkingsticks change over the course of several generations. Today we are going to start an investigation into the question of just how that kind of change can happen in a population. ...
Introduction to Adipose Tissue Adipose tissue is not merely an
Introduction to Adipose Tissue Adipose tissue is not merely an

... lipid metabolism by inducing the expression of the macrophage scavenger receptor, CD36. The CD36 receptor is also known as fatty acid translocase (FAT) and it is one of the receptors responsible for the cellular uptake of fatty acids. The role of SREBP-1c in activation of adipocyte differentiation i ...
Extended Life-Span and Stress Resistance in Drosophila
Extended Life-Span and Stress Resistance in Drosophila

... Not all the InR alleles extend longevity because the gene is highly variable. • Some alleles produced developmental defects that carry over into adults. ...
FEMS Microbiology Ecology
FEMS Microbiology Ecology

... partners in a mycelial shelter. The light-exposed joint organisms can be extremely robust to changing conditions in harsh natural environments. In these habitats, however, infections with specialized fungal parasites commonly occur. These lichen-inhabiting fungi have been recognized even before the ...
Slide 1
Slide 1

... • “Does the gene for seed shape have anything to do with the seed for seed color?” ...
H4K20me1 Contributes to Downregulation of X
H4K20me1 Contributes to Downregulation of X

... with apparently normal DCC protein localization on X ...
Virus induced gene silencing, a post transcriptional gene silencing
Virus induced gene silencing, a post transcriptional gene silencing

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Gene expression profiling



In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell.DNA microarray technology measures the relative activity of previously identified target genes. Sequence based techniques, like serial analysis of gene expression (SAGE, SuperSAGE) are also used for gene expression profiling. SuperSAGE is especially accurate and can measure any active gene, not just a predefined set. The advent of next-generation sequencing has made sequence based expression analysis an increasingly popular, ""digital"" alternative to microarrays called RNA-Seq. However, microarrays are far more common, accounting for 17,000 PubMed articles by 2006.
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