How to respond to radiological, biological and chemical threats: guide for the European
... Although the perception of risk for the intentional release of a biological agent to cause harm is different across the 27 EU MS, the risk is real and should not be ignored by the different levels of the health and public health sector. Various attempts to prioritize the biological agents of highest ...
... Although the perception of risk for the intentional release of a biological agent to cause harm is different across the 27 EU MS, the risk is real and should not be ignored by the different levels of the health and public health sector. Various attempts to prioritize the biological agents of highest ...
The airway microbiome in cystic fibrosis
... fibrosis (CF) patients has increased dramatically with one of the most important interventions being antibiotic treatment directed against pulmonary infection. Antibiotic regimens have been developed for prophylaxis, eradication of initial infection and control of chronic infection and exacerbations ...
... fibrosis (CF) patients has increased dramatically with one of the most important interventions being antibiotic treatment directed against pulmonary infection. Antibiotic regimens have been developed for prophylaxis, eradication of initial infection and control of chronic infection and exacerbations ...
Promise of Pharmacogenomics - Academy of Managed Care
... raised by the development and use of genetic technologies and their integration into clinical and public health practice. Because the scope of its charge encompasses a broad range of issues, the Committee undertook a prioritization process during its first year to help focus on areas in which policy ...
... raised by the development and use of genetic technologies and their integration into clinical and public health practice. Because the scope of its charge encompasses a broad range of issues, the Committee undertook a prioritization process during its first year to help focus on areas in which policy ...
introduction to genetic epidemiology
... The heuristic interpretation is that aggregation exists when cases of disease appear in families more often than one would expect if diseased cases were spread uniformly and randomly over individuals: “it runs in the family” Actual approaches for detecting aggregation depend on the nature of the ...
... The heuristic interpretation is that aggregation exists when cases of disease appear in families more often than one would expect if diseased cases were spread uniformly and randomly over individuals: “it runs in the family” Actual approaches for detecting aggregation depend on the nature of the ...
Free Scientific Papers Update Proctology 2011
... pain, PR bleeding, local - burning & itching. Apart from parentral route of analgesic drugs, administration of locally acting drug need to be used. Rectal drug administration could represent a convenient, alternative route of drug administration over oral route which has its own drawbacks like intol ...
... pain, PR bleeding, local - burning & itching. Apart from parentral route of analgesic drugs, administration of locally acting drug need to be used. Rectal drug administration could represent a convenient, alternative route of drug administration over oral route which has its own drawbacks like intol ...
Leukaemia Section 3q27 rearrangements in non Hodgkin lymphoma,
... in the REAL classification; very rare cases were also reported with mantle cell lymphoma and chronic lymphocytic leukemia. 3q27 breaks are usually, but not invariably, associated with rearrangements of the BCL6 gene located at the 3q27 chromosome band; likewise rearrangements of this gene may occur ...
... in the REAL classification; very rare cases were also reported with mantle cell lymphoma and chronic lymphocytic leukemia. 3q27 breaks are usually, but not invariably, associated with rearrangements of the BCL6 gene located at the 3q27 chromosome band; likewise rearrangements of this gene may occur ...
EVD - Regional Public Health
... Fever, or history of fever, with additional symptoms such as intense weakness, headache, myalgia, abdominal pain, sore throat, vomiting, diarrhoea or unexplained haemorrhage. Initial symptoms are usually not specific and may worsen after a few days, often with prostration, rash, evidence of capillar ...
... Fever, or history of fever, with additional symptoms such as intense weakness, headache, myalgia, abdominal pain, sore throat, vomiting, diarrhoea or unexplained haemorrhage. Initial symptoms are usually not specific and may worsen after a few days, often with prostration, rash, evidence of capillar ...
The evolutionary history of the CCR5-Δ32 HIV
... that drove this allele to observed frequencies has drawn considerable attention. The coincidence of the age of the allele and the infamous bubonic plague Black Death pandemic led Stephens et al. (1998) to suggest that plague had been responsible for the selective rise of the allele. Indeed, the bubo ...
... that drove this allele to observed frequencies has drawn considerable attention. The coincidence of the age of the allele and the infamous bubonic plague Black Death pandemic led Stephens et al. (1998) to suggest that plague had been responsible for the selective rise of the allele. Indeed, the bubo ...
L1-L2-Gastroesophage..
... • usually less than 20 mm in diameter but they may > 100 mm in diameter. • The classic peptic ulcer is a round to oval, sharply punched-out defect • In contrast, heaped-up margins are more characteristic of cancers • Microscopy • the base consists of necrotic tissue and polymorph exudate overlying i ...
... • usually less than 20 mm in diameter but they may > 100 mm in diameter. • The classic peptic ulcer is a round to oval, sharply punched-out defect • In contrast, heaped-up margins are more characteristic of cancers • Microscopy • the base consists of necrotic tissue and polymorph exudate overlying i ...
Chapter 9. Patterns of single
... usually have at least one affected parent (vertical transmission). Exceptions: new mutations and reduced penetrance. A child of an affected and an unaffected individual usually has a 50% chance of being affected (If the disease is rare, almost all affecteds are heterozygotes) Affects both sexes, ...
... usually have at least one affected parent (vertical transmission). Exceptions: new mutations and reduced penetrance. A child of an affected and an unaffected individual usually has a 50% chance of being affected (If the disease is rare, almost all affecteds are heterozygotes) Affects both sexes, ...
Spinal muscular atrophy: diagnosis, treatment and future prospects R A
... Objective: To report on recent genetic and molecular discoveries and on future prospects for the treatment of spinal muscular atrophy (SMA), thereby helping healthcare professionals to make a quick diagnosis and provide appropriate and timely therapeutic support. Sources: Information was collected f ...
... Objective: To report on recent genetic and molecular discoveries and on future prospects for the treatment of spinal muscular atrophy (SMA), thereby helping healthcare professionals to make a quick diagnosis and provide appropriate and timely therapeutic support. Sources: Information was collected f ...
- Wiley Online Library
... and, in fact, older adults prefer to choose among fewer options than younger adults (Reed, Mikels, & Simon, 2008), perhaps a reflection of their declining cognitive abilities. At the same time, older adults have more experience and expertise in making decisions (e.g., medical decisions), enabling th ...
... and, in fact, older adults prefer to choose among fewer options than younger adults (Reed, Mikels, & Simon, 2008), perhaps a reflection of their declining cognitive abilities. At the same time, older adults have more experience and expertise in making decisions (e.g., medical decisions), enabling th ...
West Nile Virus - Providers - Select Health of South Carolina
... cerebrospinal fluid (CSF) within eight days of illness onset (WNV IgM preferred) using Food and Drug Administration (FDA)-approved commercial test kits or CDC-defined IgM and IgG enzyme-linked immunosorbent assay (ELISA) testing. Convalescent phase serum testing to confirm negative screen or retro ...
... cerebrospinal fluid (CSF) within eight days of illness onset (WNV IgM preferred) using Food and Drug Administration (FDA)-approved commercial test kits or CDC-defined IgM and IgG enzyme-linked immunosorbent assay (ELISA) testing. Convalescent phase serum testing to confirm negative screen or retro ...
The Chicken (Gallus gallus) Z Chromosome Contains at Least Three
... mechanisms for such segmental steps of sex chromosome divergence are inversions on Y (W) and recombination restriction without inversions. Neither of these alternatives can currently be tested, as the poor assembly of the repeat-rich chicken W chromosome precludes gene-order analysis, and no antagon ...
... mechanisms for such segmental steps of sex chromosome divergence are inversions on Y (W) and recombination restriction without inversions. Neither of these alternatives can currently be tested, as the poor assembly of the repeat-rich chicken W chromosome precludes gene-order analysis, and no antagon ...
High mutation rates in human and ape pseudoautosomal genes
... another human pseudoautosomal gene, SHOX, is not higher than elsewhere in the genome (May et al., 2002). A noncoding pseudoautosomal region close to the Xp/Yp telomere was reported to have a high substitution rate (Cooke et al., 1985; Baird and Royle, 1997), however, subtelomeric regions are known t ...
... another human pseudoautosomal gene, SHOX, is not higher than elsewhere in the genome (May et al., 2002). A noncoding pseudoautosomal region close to the Xp/Yp telomere was reported to have a high substitution rate (Cooke et al., 1985; Baird and Royle, 1997), however, subtelomeric regions are known t ...
a2 - Molecular and Cell Biology
... The polycomb group protein EZH2 is involved in progression of prostate cancer Varambally et al. Prostate cancer is a leading cause of cancer-related death in males and is second only to lung cancer. Although effective surgical and radiation treatments exist for clinically localized prostate cancer, ...
... The polycomb group protein EZH2 is involved in progression of prostate cancer Varambally et al. Prostate cancer is a leading cause of cancer-related death in males and is second only to lung cancer. Although effective surgical and radiation treatments exist for clinically localized prostate cancer, ...
the genome of herpes simplex virus: structure, replication and
... and of its replication, and to explore implications which analyses of genome sequence may have for the mechanisms of replication. H SV is a member of the family Herpesviridae, a large group of viruses responsible for a variety of diseases of man and animals (Matthews, 1982). All have large, icosahed ...
... and of its replication, and to explore implications which analyses of genome sequence may have for the mechanisms of replication. H SV is a member of the family Herpesviridae, a large group of viruses responsible for a variety of diseases of man and animals (Matthews, 1982). All have large, icosahed ...
The Comparison of Transcriptomes Undergoing Waterlogging at the
... under waterlogging stress. It is interesting to note that 3.1% of differentially expressed transcripts encode products that are involved in pathways related to cell-wall loosening enzymes. An additional 6.7% of the differentially expressed transcripts were predicted to encode enzymes related to prot ...
... under waterlogging stress. It is interesting to note that 3.1% of differentially expressed transcripts encode products that are involved in pathways related to cell-wall loosening enzymes. An additional 6.7% of the differentially expressed transcripts were predicted to encode enzymes related to prot ...
Jenkins_et_al_LRM_Revision_three_Revised
... Idiopathic pulmonary fibrosis (IPF) is a progressive and inevitably fatal disease with a 5 year survival of only 20%1. With the advent of specific anti-fibrotic medications there is now hope that diseasemodification and improved survival may be realistic therapeutic goals2, 3. Advances in IPF manage ...
... Idiopathic pulmonary fibrosis (IPF) is a progressive and inevitably fatal disease with a 5 year survival of only 20%1. With the advent of specific anti-fibrotic medications there is now hope that diseasemodification and improved survival may be realistic therapeutic goals2, 3. Advances in IPF manage ...
Cellular Biology
... Recurrence risk becomes higher if more than one family member is affected If the expression of the disease in the proband is more severe, the recurrence risk is higher The recurrence risk is higher if the proband is of the less commonly affected sex The recurrence risk for the disease usually decrea ...
... Recurrence risk becomes higher if more than one family member is affected If the expression of the disease in the proband is more severe, the recurrence risk is higher The recurrence risk is higher if the proband is of the less commonly affected sex The recurrence risk for the disease usually decrea ...
Parallel Evolution of Cold Tolerance within
... higher inversion frequencies. Each cold-adapted population shows lower inversion frequencies than a closely-related warm-adapted population, suggesting that inversion frequencies may decrease with altitude in addition to latitude. Using the FST-based “Population Branch Excess” statistic (PBE), we fo ...
... higher inversion frequencies. Each cold-adapted population shows lower inversion frequencies than a closely-related warm-adapted population, suggesting that inversion frequencies may decrease with altitude in addition to latitude. Using the FST-based “Population Branch Excess” statistic (PBE), we fo ...
TITLE: Pediatric Syndromic Hearing Loss
... phenotypes between Stickler types 1 and 3, and Stickler type 2. The genes with loci responsible for STL 1, 2 and 3 are COL2A1, COL11A1, and COL11A2 respectively. Treacher Collins (TC): Also known as Fraceschetti-Zwahlen-Klein Syndrome or MandibuloFacial Dysostosis, this autosomal dominant entity is ...
... phenotypes between Stickler types 1 and 3, and Stickler type 2. The genes with loci responsible for STL 1, 2 and 3 are COL2A1, COL11A1, and COL11A2 respectively. Treacher Collins (TC): Also known as Fraceschetti-Zwahlen-Klein Syndrome or MandibuloFacial Dysostosis, this autosomal dominant entity is ...
Genetics Tutorial
... only physical. But now that you know the risk, you must weigh the consequences before making your decisions to start a family of your own, adopt, or have no children at all. I wish you the best of luck.” One more family to help ...
... only physical. But now that you know the risk, you must weigh the consequences before making your decisions to start a family of your own, adopt, or have no children at all. I wish you the best of luck.” One more family to help ...