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... The use of effective gene contents for obtaining orthogonal contrasts under HWD is summarized in Table 1. Obtaining the coefficients for the orthogonal additive contrast, wij , as zij − E(z), warrants that Σpij wij = 0, where pij , ij = 11, 12, 22, are the genotypic frequencies of the population (see ...
Math of Genetics - College of William & Mary
Math of Genetics - College of William & Mary

... paternal genotype on the top and the maternal genotype down the left side  In the center sections of the table, combine the ...
Gene Section FOXP3 (forkhead box P3) Atlas of Genetics and Cytogenetics
Gene Section FOXP3 (forkhead box P3) Atlas of Genetics and Cytogenetics

... development. Most of which are not directly related to FOXP3-mediated repression of ErbB2 (Zuo et al., 2007b). Interestingly, when we used the GeneGo MetaCore knowledgebase to analyze genes that related to ErbB2 signaling pathway, we found that FOXP3 downregulated 10 genes in this pathway. With the ...
RecA maintains the integrity of chloroplast DNA molecules in
RecA maintains the integrity of chloroplast DNA molecules in

... almost nothing is known about the DNA repair process in plant organelles, especially chloroplasts. Since the RecA protein functions in DNA repair for bacteria, an analogous function may exist for chloroplasts. The effects on chloroplast DNA (cpDNA) structure of two nuclear-encoded, chloroplast-targe ...
Transformation Lab - Towson University
Transformation Lab - Towson University

... Bacterial transformation serves as an essential basis to a number of DNA technologies. In transformation, bacteria take up exogenous (foreign) DNA and produce the genetic products (proteins) encoded in the foreign DNA. Transformation enables inexpensive and reliable production of important medical p ...
An Analysis of the Arabidopsis Pollen
An Analysis of the Arabidopsis Pollen

... and translation were underrepresented. This is surprising in light of a need for protein synthesis upon pollen germination and during pollen tube growth. The authors hypothesize that the lack of representation in the pollen transcriptome could be due to presynthesis and storage of proteins involved ...
Topologically Non-linked Circular Duplex DNA
Topologically Non-linked Circular Duplex DNA

... giving rise ultimately to a structure whose strands are topologically non-linked. Since the structures proposed by each of the above authors differ somewhat, I shall refer to them collectively by the initials TN DNA, for topologically non-linked DNA (Fig. 1). It has been known for decades that the i ...
Drafts Disorders - NewbornScreening.info
Drafts Disorders - NewbornScreening.info

... Most babies do not have symptoms right away because they are protected by their mother’s thyroid hormone for a few weeks after birth. After about three to four weeks of age babies must rely solely on their own thyroid hormone. If they don’t make enough, symptoms will show up at that time. A small nu ...
Signal Transduction and the Chemically Addressed Nervous System
Signal Transduction and the Chemically Addressed Nervous System

... and GABA (gamma-aminobutyric acid). These six are sometimes considered the "classic" neurotransmitters because they were discovered first and also because they have developed into the major target systems for psychotropic drugs. Classic neurotransmitters are relatively low-molecular weight amines or ...
Information about Rare Diseases and Scientific Inquiry
Information about Rare Diseases and Scientific Inquiry

... of the central nervous system. For reasons unknown, the normal protein, PrP, sometimes misfolds, and in its new conformational state is able to induce other PrP molecules to do the same. This wave of PrP molecules turning into prions becomes an assault on the brain, thus producing the disease sympto ...
Tumor metastasis-associated human MTA1 gene and its MTA1
Tumor metastasis-associated human MTA1 gene and its MTA1

... cells resulted in 10–20-fold increase in reporter expression over poorly MTA1-expressing cells. Since it was reported that nucleosome remodeling histone deacetylase complex (NuRD complex) involved in chromatin remodeling contains MTA1 protein and a MTA1-related protein (MTA2), we examined NuRD compl ...
MicroRNAs: key participants in gene regulatory networks
MicroRNAs: key participants in gene regulatory networks

... for miR165 encoded HD-Zip transcription factors. The potential complementary sites might explain the ectopic expression previously described for mutations in these genes. It seemed that complementarity to miR165 was required for confining these mRNA’s accumulation to the proper cell types [33]. Ta ...
MTHFR C677T and A1298C: Explained In Plain
MTHFR C677T and A1298C: Explained In Plain

... One of the biggest concerns for those with an MTHFR mutation is the effect it may have on homocysteine levels in the blood. Homocysteine is an amino acid linked to a wide range of health problems, and is an independent risk factor for heart disease, stroke and other forms of cardiovascular disease ...
Evolution of the vertebrate jaw: comparative embryology and
Evolution of the vertebrate jaw: comparative embryology and

... Dlx and Otx genes The shared developmental features identified between the lamprey and gnathostomes are most likely to represent the ancestral programme possessed by the common ancestor (Fig. 3B; also see Trainor et al. 2003, for a similar method of speculation), whereas there can also be programmes ...
(1977) New Genes for Resistance to the Brown Planthopper in Rice
(1977) New Genes for Resistance to the Brown Planthopper in Rice

... tall tropical cultivars have been identified that are highly resistant to the brown planthopper (9, 10). Someof these cultivars are being used as sources of resistance in breeding programs at IRRI and elsewhere (6). Inheritance of resistance to the brown planthopper in six cultivars was investigated ...
The DpnI/DpnII pneumococcal system, defense against foreign
The DpnI/DpnII pneumococcal system, defense against foreign

... of SSB proteins (Fig. 3A).12 Could there be a utility for homologous transformation in methylation of ssDNA by DpnA in the reservoir, since such DNA could be methylated by DpnM in the form of dsDNA once integrated into the heteroduplex? This could be useful during transformation of homologous DNA wi ...
Mining Multi-Faceted Overviews of Arbitrary Topics in a Text Collection
Mining Multi-Faceted Overviews of Arbitrary Topics in a Text Collection

... regardless of whether it contains any extra information. • To study how different methods affect the final generated summary, we evaluated them based on the precision of best five sentences for each facet separately. • The results are shown in Table 2 and 4. ...
“Genes” and “Mutations” - Native American Cancer Research
“Genes” and “Mutations” - Native American Cancer Research

... NOTE: PCR stands for polymerase chain reaction. This is the method that allows researchers to copy and amplify almost any piece of DNA to better understand it. Many of the genetic tests currently in use require PCR as part of the process of determining if the patient has a SNP Bemis, UMN-Duluth, Bur ...
Full Text
Full Text

... If the notochord precursor cells isolated in the early phase of the ...
Engineering of steroid biotransformation in rhodococcus van
Engineering of steroid biotransformation in rhodococcus van

... Molecular tools for Rhodococcus species Bioengineering of the steroid catabolic pathway at the molecular level requires a genetically accessible Rhodococcus strain capable of rapidly degrading sterols. R. erythropolis strain SQ1 was chosen in a comparative study of several Rhodococcus strains as a s ...
Specification of floral organs in Arabidopsis
Specification of floral organs in Arabidopsis

... with the sterile organs of the perianth (i.e. sepals and petals), the vast majority of these transcripts were assigned to stamens and carpels, implying that highly specialized gene expression programmes underlie the formation of these organ types. One caveat of these studies was that they were typic ...
Scientific background report AMFLORA potato
Scientific background report AMFLORA potato

... antibiotic kanamycin is present, only those plants carrying the nptII gene and demonstrating kanamycin resistance will develop. Plants that carry the nptII gene will carry the gbss gene as well, since the two are coupled in one and the same piece of DNA. So this is a very simple way to select only t ...
Bruce Wallace Biotechnology Lab Program Student Guide 5th
Bruce Wallace Biotechnology Lab Program Student Guide 5th

... Beta lactamase, then, enables bacteria to reproduce in the presence of ampicillin. In addition, pARA carries a gene for the AraC protein, a protein that helps the bacterium make proteins encoded by genes inserted into this plasmid. A gene, even a foreign one, can be expressed (produced) if it is ins ...
Ribosomal Protein RPL27a Promotes Female Gametophyte
Ribosomal Protein RPL27a Promotes Female Gametophyte

... developmental phenotypes. Why ribosomal protein mutants have specific phenotypes is not fully known but such defects potentially result from ribosome insufficiency, ribosome heterogeneity or extra-ribosomal functions of ribosomal proteins. Here, we report that ovule development is sensitive to the l ...
CONSERVATION AND DIVERGENCE IN MOLECULAR
CONSERVATION AND DIVERGENCE IN MOLECULAR

... Many organisms manifest polarity at some level; indeed, asymmetry seems essential for promoting meaningful interaction with the environment. Even the simplest unicellular organisms display temporary polarity in response to their environment; for example, in reception and response to chemotactic sign ...
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Nutriepigenomics

Nutriepigenomics is the study of food nutrients and their effects on human health through epigenetic modifications. There is now considerable evidence that nutritional imbalances during gestation and lactation are linked to non-communicable diseases, such as obesity, cardiovascular disease, diabetes, hypertension, and cancer. If metabolic disturbances occur during critical time windows of development, the resulting epigenetic alterations can lead to permanent changes in tissue and organ structure or function and predispose individuals to disease.
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