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slg mock midterm – for practice only
slg mock midterm – for practice only

... 14. Rachel and Ross just got married. Ross was married once before and had albino child. Rachel has an albino sister. Neither Ross, Rachel, nor any of their parents are albinos. Calculate the probability that Ross and Rachel will have an albino child. Albinism is an autosomal recessive disorder. a. ...
PowerPoint Presentation - Antigenic variation in Trypanosoma brucei
PowerPoint Presentation - Antigenic variation in Trypanosoma brucei

... proteins is transcribed by the RNA polymerase Pol2 (this enzyme can be inhibited by the toxin a amanitin)  Ribosomal RNA is generally transcribed by Pol1 (which is resistant to the toxin)  VSG transcription is insensitive to aamanitin suggesting it is transcribed by the highly processive Pol I (ho ...
Chapter 5 PRINCIPLES OF INHERITANCE AND VARIATION One
Chapter 5 PRINCIPLES OF INHERITANCE AND VARIATION One

... and intercrossed their F1 progeny. He observed that the two genes did not segregate independently of each other and the F2 ratio deviated very significantly from 9:3:3:1. Morgan found that even when genes were grouped on the same chromosome, some genes were very tightly linked (showed very low recom ...
DNA STRUCTURE - Teachers Network
DNA STRUCTURE - Teachers Network

... It is used to ____________________________________________________________________________. a. _________________________ _____________________ are used to cut the DNA. How does it know where to cut the DNA? b. After the DNA is cut, it is inserted into the gel. Then the gel is turned on. Which pieces ...
Ch 11 RNO
Ch 11 RNO

... 5. Differentiate between phenotype and genotype. 6. How can a Punnett Square be used to predict the outcomes of genetic crosses? a. Be able to make predictions for an F₁ generation. 7. Describe a two-factor, or “dihybrid”, cross. a. Be able to successfully complete a dihybrid cross using a Punnett s ...
Patterns of Inheritance
Patterns of Inheritance

... • He demonstrated with pea plants that both parents pass on to their offspring genetic factors that remain separate generation after generation. • Today the concept of genes has replaced Mendel’s vague idea of factors. • Gene: is a segment of DNA whose sequence of nucleotides codes for a specific fu ...
Lab 4 Restriction Analysis
Lab 4 Restriction Analysis

... containing thousands of genes. The only way to break it into smaller segments was to physically shear it. But these fragments would be random, not reproducible, and were rapidly degraded by cellular nucleases if reintroduced into the cell. RE's, for the first time, allowed scientists to cut DNA into ...
Epigenetic and genetic factors affect transgene
Epigenetic and genetic factors affect transgene

... In order to account for the segregation of these phenotypes from diploid Fi ova, the expression of this locus must either be subject to allelic exclusion (if expression begins prior to meiosis in the oocyte) or expression must not begin until the completion of meiosis, i.e. after formation of the se ...
Detecting phenotype-specific interactions between
Detecting phenotype-specific interactions between

... chains of amino acids - proteins ...
linkage-recomb2
linkage-recomb2

... a crossover value (COV) A recombinant frequency (COV) of 1% represents one unit of measure on the genetic map. If genes A/a and B/b show a recombination frequency of 9%, then they will be: 9 units apart on the genetic map. ...
Causes, Risks, Prevention
Causes, Risks, Prevention

... and it’s not clear how this might affect any risk. These risks are being studied, but it will probably be many years before firm conclusions can be made. In the meantime, for people concerned about the possible risks, there are ways to lower your exposure, such as using an earpiece to move the phone ...
Bombay Phenotype
Bombay Phenotype

... What does it mean to lack the H substance? •Must have the H substance to make antigen A or B •Can only receive a blood transfusion from other individuals with the Bombay phenotype –OhOh ...
Genomes and SNPs in Malaria and Sickle Cell Anemia
Genomes and SNPs in Malaria and Sickle Cell Anemia

... and can lead to several complications including anemia. Sickle cell anemia is more common in regions where malaria is present. Sickle-shaped blood cells provide some resistance to malaria. Individuals with the sickle cell variation are less likely to get infected by malaria, and if infected they sho ...
DNA, RNA and Proteins
DNA, RNA and Proteins

... In cells three types of RNA complement DNA and translate the genetic code into proteins. RNA vs. DNA ◦ Both have four bases and carry genetic information. ◦ RNA is composed of one strand of nucleotides and DNA is composed of two strands of nucleotides. ◦ RNA substitutes Uracil for Thymine. ...
File
File

... DNA Fingerprinting Activity Introduction: DNA fingerprinting relies on the fact that the DNA code is universal for all living things and that there are differences between individuals within that code. Because human DNA is very similar to every other human’s DNA, DNA fingerprinting primarily focuses ...
Microbial Genetics
Microbial Genetics

... • This process can only be mediated by temperate phages. • The only genes that can be transferred from the donor to the recipient are the genes that are immediately adjacent to the phage insertion site on the donor chromosome. • When the phage DNA is excised from the chromosome as the virus enters i ...
Carcinomas with DNA Mismatch Repair Deficiency
Carcinomas with DNA Mismatch Repair Deficiency

... methylation, including promoter silencing of genes that are important to tumor biology.[231] Referred to as the CpG island methylator phenotype (CIMP), this includes most sporadic MSI-H cancers with methylation silencing of MLH1.[ ...
Biology 102A
Biology 102A

... c. trisomy 3. ___ occurs when chromosomes overlap and genes change places. a. chromosomal b. crossing over c. point 4. In ___ a needle withdraws a small amount of fluid from around the fetus for testing. ...
DNA Structure and Replication
DNA Structure and Replication

Mendelian Genetics
Mendelian Genetics

... Inherited traits: Characteristics that are inherited or passed on from parents to offspring Acquired traits: characteristics that you get as you go through life (not inherited) Gregor Mendel: the father of genetics. ˃ Mendelian Genetics ˃ He worked with garden pea inheritance in the 1800’s. ˃ His id ...
Lec 08 - Development of e
Lec 08 - Development of e

... Auerbach, who showed that nitrogen mustard (component of poisonous mustard gas used in World Wars I and II) could cause mutations in cells. Since that time, many other mutagenic chemicals have been identified and there is a huge industry and government bureaucracy dedicated to finding them in food a ...
presentation - Harlem Children Society
presentation - Harlem Children Society

... Inoculated the strains into flasks and put them in a 30 degree C shaker Measure their Optical Density(OD) If they all reach .5 great but if not then I would have to spin them down for about 10 minutes. Dilute so that it’s 3.3 x10 6 cells/ml2 using the Dimensional Analysis technique. Then inoculate o ...
Genetics
Genetics

... lactose/galactose from the diet. ...
Y genetic variation and phenotypic diversity in health and disease
Y genetic variation and phenotypic diversity in health and disease

... and prevalence of many cardiovascular diseases [38]. Blood pressure is a risk factor associated with cardiovascular disease, and rodent models of hypertension have identified ChrY as a contributor to hypertension in males. A rat model was used to investigate the genetic mechanism driving spontaneous ...
Mapping Disease Genes
Mapping Disease Genes

... affected offspring. However, you only see families with at least 1 affected child, so you miss all those families that by chance didn’t have any affected children. – 16 families, each with 2 children. Each child has a 3/4 chance of being normal, so with 2 children the chance of having no affected ch ...
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Nutriepigenomics

Nutriepigenomics is the study of food nutrients and their effects on human health through epigenetic modifications. There is now considerable evidence that nutritional imbalances during gestation and lactation are linked to non-communicable diseases, such as obesity, cardiovascular disease, diabetes, hypertension, and cancer. If metabolic disturbances occur during critical time windows of development, the resulting epigenetic alterations can lead to permanent changes in tissue and organ structure or function and predispose individuals to disease.
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