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O - Faculty Web Pages
O - Faculty Web Pages

Normal BRCA1 gene
Normal BRCA1 gene

... The function of the BRCA1 protein is to prevent our cells from becoming cancerous. If a cell is dividing too much, the BRCA1 protein can repair the cell so that it undergoes mitosis normally. A portion of the BRCA1 gene (the DNA with instructions on how to make the BRCA1 protein) is shown below. TAC ...
topic 4 genetics
topic 4 genetics

... sickle-cell allele is codominant; homozygote/HbS HbS have sickle cell anemia/is lethal / heterozygote/HbS HbA has the sickle trait/is carrier (and is more resistant to malaria); ...
BDOL Interactive Chalkboard
BDOL Interactive Chalkboard

... Diagnosis of genetic disorders • The DNA of people with and without a genetic disorder is compared to find differences that are associated with the disorder. Once it is clearly understood where a gene is located and that a ____________ in the gene causes the disorder, a diagnosis can be made for an ...
Document
Document

... different versions of one gene; polygenic traits are influenced by multiple genes ...
Eigen-R2 for dissecting variation in high
Eigen-R2 for dissecting variation in high

... With thousands of response variables, one can calculate R2 values for each one, resulting in thousands of these values. Even though it is reasonable to simply plot the distribution of these R2 values, sometimes it is also desirable to calculate an average R2 , so that statements can be made about th ...
Select one of your Biology instructors from another class and look
Select one of your Biology instructors from another class and look

... these cereal grasses are highly sterile and have many characteristics intermediate between the parental species. How many chromosomes do the hybrids possess? 3.2 The diagrams shown here depict anaphase in cell division in a cell of a hypothetical organism with two pairs of chromosomes. Identify the ...
PAG2006workshop
PAG2006workshop

... Markers: Find a marker based upon name, type or species; View it’s detail; Link to the maps, literature and ontologies databases. Proteins: Find a protein and it’s sequence; Determine it’s cellular location and function; Explore protein families; Link to ontologies and literature databases. Genes: L ...
S3 Text.
S3 Text.

... Because we simulated the data, by design, the correct answer for the algorithm is three clusters with different variance parameters, i.e. 3-V for Test Cases 1 and 3, and 3-E for Test Case 2. For a given number of clusters, the mixture model will assign a score (the Bayesian Information Criterion, BI ...
Powerpoint template for scientific posters (Swarthmore
Powerpoint template for scientific posters (Swarthmore

... • Major difference in our work and Pollard’s was our samples. Pollard solely used pediatric samples, while we used both pediatric and adult AML samples. Pollard also had ~5x more samples than our lab (203 compared to 41), thus, the sample size and type may have affected our results. • Pollard et al. ...
Arabidopsis is Cool
Arabidopsis is Cool

... June 27, 2008 ...
Introduction to Genetics
Introduction to Genetics

... plants to better understand heredity, sometimes referred to as the father of modern genetics, came up with Principle of Dominance. The principle of dominance states that some alleles are dominant and some are recessive. The dominant allele is seen when in combination with itself or a recessive allel ...
Enhancers reside in a unique epigenetic environment during early
Enhancers reside in a unique epigenetic environment during early

AQA A2 level Biology
AQA A2 level Biology

... polypeptides they don’t need or that they can get from their environment. This is more efficient and less wasteful than making everything all the time. Certain cells do not need certain genes. 8 What is an operon? Explain why they are important to prokaryotes. An operon is a group of genes that may ...
Progressive rod-cone degeneration (PRCD) in selected dog breeds
Progressive rod-cone degeneration (PRCD) in selected dog breeds

... gion, but others do not have any obvious role. It has been proposed that these conserved canine/ human sequences might represent unidentified genes or sequences that regulate processes such as transcription, replication, and chromosome pairing and condensation (Frazer et al., 2001). To establish mor ...
Example 2. - the Gene Ontology Consortium Wiki
Example 2. - the Gene Ontology Consortium Wiki

... Figure 2. Recombinant CYR61 induces BMP-2 expression. A and B, RT-PCR for mRNA of different BMP family members is shown. The coding regions of cDNA were used as probes as indicated under “Experimental Procedures.” A GAPDH probe was used as an internal control for RNA quantity. C, MC3T3-E1 cells wer ...
Chapter 9 - Personal
Chapter 9 - Personal

... – One gene influencing many characteristics – The gene for sickle cell disease ...
Bone mineral density in pediatric inflammatory bowel disease
Bone mineral density in pediatric inflammatory bowel disease

... Low bone mineral density (BMD) has been highlighted as a potential problem in children with inflammatory bowel disease (IBD), which is one of the most common chronic childhood diseases in the westernized world. The mechanisms behind reduced BMD in pediatric IBD are still not completely understood, b ...
A1993LB48800002
A1993LB48800002

... In the 1960s, 1970s, and early 1980s, it was common practice to characterize and correlate a cytochrome P450 enzyme activity with a partially purified protein (antigen) and/or antibody. Each laboratory then assigned the P450 its own name, few investigators were willing to share antigens or antibodie ...
DNA Structure, Function and Replication – Teacher Notes
DNA Structure, Function and Replication – Teacher Notes

... I estimate that this activity will require roughly one 50-minute period, depending on your students and how much they know about DNA before beginning this activity. I recommend that you use the PDF of the Student Handout for photocopying since some of the figures in the Student Handout may not displ ...
Genetics
Genetics

... to gray coat color in mice, what do you know about the genotype of a mouse with gray coat color? Why? ...
Unit 3 - OrgSites.com
Unit 3 - OrgSites.com

... 9. The life cycles of sexual organisms can differ in their timing of fertilization and meiosis, the level of development of the haploid generation (single-celled or multicellular), and the level of development of the diploid generation. Look at figure 13.6 and briefly draw/describe the characterist ...
principles of inheritance and variation
principles of inheritance and variation

... dominates the other (as in the F1) and hence is called the dominant factor while the other factor is recessive Mendel crossed the tall plant from F2 with a dwarf plant. This he called a test cross. In a typical test cross an organism (pea plants here) showing a dominant phenotype (and whose genotyp ...
File S2 - Genes | Genomes | Genetics
File S2 - Genes | Genomes | Genetics

Expression analysis of a chicory fructan 1‐exohydrolase gene
Expression analysis of a chicory fructan 1‐exohydrolase gene

... localized in the vacuoles, it might be expected that plant 1FEH cDNAs would be more closely related to the vacuolar invertases; however, unexpectedly, based on sequence alignments, 1-FEH is more similar to the cell wall invertases than to vacuolar invertases (Van den Ende et al., 2000, 2001). Low te ...
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Nutriepigenomics

Nutriepigenomics is the study of food nutrients and their effects on human health through epigenetic modifications. There is now considerable evidence that nutritional imbalances during gestation and lactation are linked to non-communicable diseases, such as obesity, cardiovascular disease, diabetes, hypertension, and cancer. If metabolic disturbances occur during critical time windows of development, the resulting epigenetic alterations can lead to permanent changes in tissue and organ structure or function and predispose individuals to disease.
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