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Non-cell-autonomous regulation of root hair patterning genes by
Non-cell-autonomous regulation of root hair patterning genes by

... The establishment of a pattern of files forming root hairs and non-root hairs in the root epidermis is a wellstudied developmental model system (Schiefelbein et al., 2009; Tominaga-Wada et al., 2011; Grebe, 2012). Root hair cells (H-cells) develop from cell files over the cleft of two underlying cor ...
PERSPECTIVES IN HUMAN GENETICS Mendelian Inheritance in
PERSPECTIVES IN HUMAN GENETICS Mendelian Inheritance in

... MIM has been maintained on computer since early 1964.15 In those pre–word processor days, maintenance on the mainframe computer was a boon to the updating process and facilitated preparation of camera copy, including author and subject indices, for book publication. That advantage for book publicati ...
Characterization of the Arabidopsis thaliana Mutant pcb2 which
Characterization of the Arabidopsis thaliana Mutant pcb2 which

... phyll a, and the peripheral light-harvesting antenna complexes contain chlorophyll a and chlorophyll b (Grossman et al. 1995). There are some other kinds of chlorophyll found in various photosynthetic organisms, such as bacteriochlorophylls in photosynthetic bacteria. Prochlorococcus, a group of mar ...
PersPecTIves - Ralf Sommer
PersPecTIves - Ralf Sommer

... and β-catenin-independent functions16. Therefore, studies that rest on the analysis of expression patterns of shared components of such pathways can easily be misleading. Only functional investigations and comparisons between a developmental model system and an evo–devo ‘model system’ can reveal how ...
49 What is the etiologic factor of the monogenic inherited pathology?
49 What is the etiologic factor of the monogenic inherited pathology?

... 70 Which symptoms are not typical for autosomal recessive type of inheritance? A The disease occurs equally in men and women B affected parents can have healthy children C Parents of patient are clinically (by phenotype) healthy D The parents are blood relatives. E The more children in the family, t ...
Monitoring BCR-ABL transcript levels by real-time
Monitoring BCR-ABL transcript levels by real-time

... Real-time quantitative polymerase chain reaction (RQPCR) of BCR-ABL hybrid transcripts is now the standard method for monitoring the response to treatment in patients with chronic myeloid leukemia (CML) who have been induced into complete cytogenetic remission.1 Recently, various methods based on RQ ...
gramene_ontologytutorial
gramene_ontologytutorial

... Each 'child term' has a unique relationship to its 'parent term'. Instance of (is a, type of): Used to describe the relationship between a child term that represents a specific type of a more general parent term. For example: a caryopsis is a type of fruit; a panicle is an inflorescence. Part of: U ...
PDF
PDF

... tively. We find that the accuracy of FirstEF is significantly higher for CpG-related than non-CpG-related genes. To study the performance of FirstEF on the genome scale, we ran it on human chromosomes 21 and 22 and compared the predictions with the experimentally chromosomes 21 and 22. We downloaded ...
Evolution of the Actin Gene Family in Testate Lobose Amoebae
Evolution of the Actin Gene Family in Testate Lobose Amoebae

... PCR amplification yields artifactual recombinants (chimeras) when multiple closely related target sequences are present in the mixture (Judo et al. 1998). We chose to rely on an empirical strategy, performing extensive PCR-artifact formation experiments in our study system to determine chimera-reduc ...
Tomé, S., Manley, K., Simard, J.P., Clark, G.W., Slean, M.M., Swami
Tomé, S., Manley, K., Simard, J.P., Clark, G.W., Slean, M.M., Swami

... congenic mice homozygous for the B6 Msh3 gene on a CBy background, while the CAG tract was stabilized in congenics homozygous for the CBy Msh3 gene on a B6 background. The CAG stabilization was as dramatic as genetic deficiency of Msh2. The B6 and CBy Msh3 genes had identical promoters but differed ...
Medical genetics_1
Medical genetics_1

... 70 Which symptoms are not typical for autosomal recessive type of inheritance? A The disease occurs equally in men and women B affected parents can have healthy children C Parents of patient are clinically (by phenotype) healthy D The parents are blood relatives. E The more children in the family, t ...
Association of functionally significant Melanocortin
Association of functionally significant Melanocortin

... provided by its agonist a-MSH and an orexigenic signal provided by its antagonist agouti-related protein (12,13). Both of these ligands are expressed in distinct neuronal populations of the arcuate nucleus of the hypothalamus and are coordinately regulated by the adipocyte-secreted hormone, leptin, ...
View PDF - OMICS International
View PDF - OMICS International

... the initial clinical impression was of a chronic hepatitis, the laboratory investigations for infectious or autoimmune hepatitis and/or Wilson’s disease were negative. The child was addressed to the department of pediatric neurology, where she performed muscle laboratory tests that showed elevated C ...
Integrated genome sequence and linkage map of physic nut
Integrated genome sequence and linkage map of physic nut

... 812 Pingzhi Wu et al. of the connected contigs was generally correct. Third, we used the LASTZ program to perform whole genome scaffoldto-scaffold alignment of our physic nut genome assembly (632 scaffolds were covered) with that presented by Hirakawa et al. (2012). The two genomes exhibited good c ...
Homeotic genes regulate the spatial expression
Homeotic genes regulate the spatial expression

... morphology by coordinating the spatial and temporal transcription patterns of target or 'realizator' genes (Garcia-Bellido, 1977). In the epidermis, the nervous system, and the visceral mesoderm, cross-regulatory interactions have been observed among the homeotic genes; thus the first target genes t ...
Polydactyl Maine Coons
Polydactyl Maine Coons

... reached America with early British settlers hence their greater frequency in Eastern states. A disproportionately high number of "lucky" polydactyl cats, compared to normal-toed cats, would have found their way there. This would lead to a greater proportion of polydactyls than usual for a random-bre ...
Wheat biotechnology: A minireview
Wheat biotechnology: A minireview

... Scorable markers Initial steps for genetic transformation involves delivery of a gene cassette into recipient cells followed by analysis of the expression of delivered gene. The results of the above events can be detected by assaying the expression of a reporter gene introduced into plant cell cultu ...
Speciation and Gene Flow between Snails of Opposite Chirality
Speciation and Gene Flow between Snails of Opposite Chirality

... common chiral morph to fixation. This therefore suggests a general mechanism as to how chiral variation arises in snails. In populations that contain both chiral morphs, two different situations are then possible. In the first, gene flow is substantial between morphs even without interchiral mating, ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... endocrine disorder in women of reproductive age and is considered as a multifactorial reproductive, cosmetic and metabolic problem. The etiology of PCOS is not well understood and its pathophysiological and molecular basis is still obscure. PCOS is likely to be the outcome of a number of both geneti ...
Chromatin Evolution and Molecular Drive in Speciation
Chromatin Evolution and Molecular Drive in Speciation

... but male hybrids are sterile (for a review see [94]; see also [95, 96]). Backcross analyses have indicated that three or more independently segregating loci are involved in this male hybrid sterility. One gene, Hybrid sterility 1 (Hst1) of M. m. domesticus, is polymorphic: the Hst1s allele causes st ...
The Mobile Genetic Element Alu in the Human Genome
The Mobile Genetic Element Alu in the Human Genome

... responsible for innumerable genetic disorders, can be markers for human identification and are raw material for evolution mine the molecular basis of a growing number of identified diseases and to provide new. directions in genome mapping and biomedical research. Only a small fraction of the human g ...
December 8, 2006 - Brandeis University
December 8, 2006 - Brandeis University

... Experimental errors might have also influenced the progeny count. Incubation conditions may not have allowed for proper fly development. An incubation temperature set too high, for example, may have made female flies sterile, affecting the progeny count. It is also still possible that some female fl ...
iron-regulatory protein 1
iron-regulatory protein 1

... in the 5th exon, and led to a deletion of 8 bp, and to the addition of 5 bp extra sequence at the 3 -junction. The aco3-1 line has ...
The Origin of Subfunctions and Modular Gene Regulation
The Origin of Subfunctions and Modular Gene Regulation

... regulatory element (A). Consecutive regulatory element accretion events involving B and C sites produce an enhancer that redundantly drives expression in both tissues. Degenerative mutations lead to the loss of the ancestral positive regulatory element (A), resulting in an enhancer with semi-indepen ...
The Origin and Development of Neural Crest
The Origin and Development of Neural Crest

... therefore select the migratory path because they are specified. Alternatively, the presence of extrinsic factors in the environment through which the cells migrate may contribute to the specification of melanocytes. In support of this latter theory, adhesion molecules, including Ephrin-B (EphB), ext ...
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Nutriepigenomics

Nutriepigenomics is the study of food nutrients and their effects on human health through epigenetic modifications. There is now considerable evidence that nutritional imbalances during gestation and lactation are linked to non-communicable diseases, such as obesity, cardiovascular disease, diabetes, hypertension, and cancer. If metabolic disturbances occur during critical time windows of development, the resulting epigenetic alterations can lead to permanent changes in tissue and organ structure or function and predispose individuals to disease.
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