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THE EFFECT OF INBREEDING ON THE VARIATION DUE TO
THE EFFECT OF INBREEDING ON THE VARIATION DUE TO

Dissecting plant meiosis using Arabidopsis thaliana mutants
Dissecting plant meiosis using Arabidopsis thaliana mutants

... nucleolus (arrowed). (f) Metaphase I in mei1/mcd1 illustrating the severe chromosome fragmentation which occurs in this mutant, (g) dyad stage in the mei1/mcd1 mutant showing the acentric chromosome fragments which are not incorporated in either nucleus, (h) metaphase II in wild type showing ®ve chr ...
Clinical and Molecular Aspects of Diseases of Mitochondrial DNA
Clinical and Molecular Aspects of Diseases of Mitochondrial DNA

... Mitochondria within human cells contain vast numbers of mitochondrial DNA (mtDNA), which are small, circular, and double-stranded. The proper functions of mtDNA depend totally on specific proteins that are encoded by the nucleus and then imported into mitochondria. Thus instability of mtDNA can stem ...
Risk of Gastric Cancer in Hereditary Nonpolyposis Colorectal
Risk of Gastric Cancer in Hereditary Nonpolyposis Colorectal

... gastric cancer, than that of hMSH2 (18 –20), and almost all mutations in Korean HNPCC patients were located in the hMLH1 gene (15, 16). Therefore, this unique mutational spectrum should also be considered in interpreting the lower relative risk. Various environmental factors are known to be associat ...
Analysis of 16S ribosomal RNA gene segments for the diagnosis of
Analysis of 16S ribosomal RNA gene segments for the diagnosis of

... Urology and Nephrology Center (UNC), Mansoura University Hospital (MUH), Pediatric University Hospital (PUH). ...
A Haploid System of Sex Determination in the Brown Alga - Hal-CEA
A Haploid System of Sex Determination in the Brown Alga - Hal-CEA

... The male SDR haplotype contains 17 protein coding genes and three pseudogenes, whereas 15 protein-coding genes and seven pseudogenes were found in the female haplotype (Figure 1C, Figure 3, Table S2). Eight of the female protein coding genes and three of the pseudogenes are homologous to male SDR s ...
Extrapolation to the whole human genome
Extrapolation to the whole human genome

PCDH19-related Infantile Epileptic Encephalopathy - HAL
PCDH19-related Infantile Epileptic Encephalopathy - HAL

... In contrast, females with heterozygous PCDH19 mutations present with early intractable seizures and a variable degree of mental retardation. PCDH19 is located in a region submitted to Xinactivation in females [Dibbens et al., 2008]. Random X-inactivation in mutated females is expected to lead to tis ...
Biophysics 101 Genomics and Computational Biology
Biophysics 101 Genomics and Computational Biology

... Sugar-binding and crystallographic studies of an arabinose-binding protein mutant (Met108Leu) that exhibits enhanced affinity & altered T7 RNA polymerase mutants with altered promoter specificities. The specificity of carboxypeptidase Y may be altered by changing the hydrophobicity of the S'1 bindin ...
Sex-specific Trans-regulatory Variation on the Drosophila melanogaster X Chromosome
Sex-specific Trans-regulatory Variation on the Drosophila melanogaster X Chromosome

... Since we were exclusively interested in trans-regulation (and since cis-regulation of these lines has previously been explored [44]), we excluded all identified SNPs located within 10 kb from the 5’ and 3’ ends of the gene in focus (i.e. SNPs associated in cis [44]). This means a cis-acting SNP for ...
GENETIC CALCULATOR (BUDGERIGAR) Help File
GENETIC CALCULATOR (BUDGERIGAR) Help File

... button. Selecting NORMAL from this list means that the selected bird contains no other genes from list, but may or may not contain genes from other lists in other Variety Combination windows, VARIETY INFORMATION The complete genetic picture for Crests is still not known. It is believed that Crests a ...
Association of a novel TAS2R38 haplotype with
Association of a novel TAS2R38 haplotype with

... these beverages and its consumption. In addition to bitter taste, the role of other tastes in alcohol intake has been analyzed. For example, it was reported that subjects who are at risk of alcoholism by having an alcoholic father, rated salty and sour solutions as more unpleasant than those with no ...
Quantitative Genetics
Quantitative Genetics

... career many of the members ever considered. ''It's in our blood'' said Brian Jacobsen, president of Madison Park Greetings, a stationery and gifts company. Mr. Jacobsen's brother, mother, grandfather, two uncles, two cousins and an aunt all started and ran their own companies and say they cannot ima ...
The Inheritance of Penicillin Titre in Crosses between
The Inheritance of Penicillin Titre in Crosses between

... heterokaryon compatibility (h-c) groups (Merrick, I 975), since these groups are genetically diverse (Jinks et al. 1966;Merrick & Caten, 1975a).Each of the initial isolates presumably carried different genes and/or alleles affecting penicillin titre, leading to the establishment of different high-ti ...
Identification and Isolation of Dominant Susceptibility Loci for
Identification and Isolation of Dominant Susceptibility Loci for

... Rheumatoid arthritis is a chronic inflammatory autoimmune disorder, controlled by multiple genes as well as environmental factors. With animal models, like the pristane-induced arthritis (PIA) in rats, it is possible to reduce the environmental effects and the genetic heterogeneity to identify chrom ...


... GLFG nucleoporin, Nup98, is an essential component of multiple RNA export pathways. J Cell Biol 1997 Jan ...
D. melanogaster - GEP Community Server
D. melanogaster - GEP Community Server

Ectocarpus
Ectocarpus

Model information sheet - EU
Model information sheet - EU

... enlarged lymphoid follicles containing multiple germinal centres. Later in life a second phase of lymphoproliferation occurs; this is characterised by extreme plasma cell hyperplasia in lymphoid tissue throughout the body (ILAR, 1989). An increased incidence of lymphoma has been reported (East, 1970 ...
Selecting an Ontology for Biomedical Text Mining He Tan, Patrick Lambrix Abstract
Selecting an Ontology for Biomedical Text Mining He Tan, Patrick Lambrix Abstract

... Verification We checked the consistency and redundancy in the UMLS Semantic Network and GENIA ontologies, respectively, by translating them into OWL format and then sending to the reasoner, Racer. Both of them are consistent and have minimal representations. Evaluation We perform two evaluations. Th ...
Mendel & Heredity
Mendel & Heredity

... and how it will function DNA is passed down from parents to offspring during reproduction In sexually reproducing organisms (ex. humans), the DNA comes from 2 parents and is passed down through special cells called gametes ...
CHK2 kinase: cancer susceptibility and cancer therapy – two sides
CHK2 kinase: cancer susceptibility and cancer therapy – two sides

... with a number of other substrates. In particular, in response to etoposide-induced double-strand breaks, CHK2 phosphorylates S364 of the E2F1 transcription factor (from the E2F family), resulting in its stabilization, transcriptional activation and induction of apoptosis through a p53-independent me ...
Acanthamoeba mitochondrial 16S rDNA sequences: inferred
Acanthamoeba mitochondrial 16S rDNA sequences: inferred

... reproduction is asexual. In asexual reproduction, the assignment of species names becomes more arbitrary and totally depends on the ability to distinguish subgroups on the basis of other characteristics that are consistently reliable. Until the present time, efforts to classify Acanthamoeba species ...
Frequent, independent transfers of a catabolic gene from bacteria to
Frequent, independent transfers of a catabolic gene from bacteria to

... genomic rearrangements have shaped eukaryotic genomes [1]. However, genetic innovation can also result from the acquisition of exogenous genes by horizontal gene transfer (HGT). Prokaryotes adapt largely by HGT, and strains of a particular species can differ by large fractions of their genome [2–6]. ...
improving pritikin - Soil and Health Library
improving pritikin - Soil and Health Library

... and disease — I finally put aside my prejudice and read "The Health Revolution". I was most impressed by the book and realized the tremendous amount of research that had gone into the formulation of Ross's ideas. Nathan Pritikin's own story, related in "The Pritikin Program", convinced me further to ...
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Nutriepigenomics

Nutriepigenomics is the study of food nutrients and their effects on human health through epigenetic modifications. There is now considerable evidence that nutritional imbalances during gestation and lactation are linked to non-communicable diseases, such as obesity, cardiovascular disease, diabetes, hypertension, and cancer. If metabolic disturbances occur during critical time windows of development, the resulting epigenetic alterations can lead to permanent changes in tissue and organ structure or function and predispose individuals to disease.
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