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Reporter Genes and Traps
Reporter Genes and Traps

... region to the gene’s promoter region allowing the scientist to follow in on the gene's activity (i.e synthesis of functional proteins), when the gene is turned on, it not only synthesizes proteins it synthesizes the reporter gene as well, thus a scientist can detect when and where the gene is active ...
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No Slide Title

... e.g., Bork group - associate pathological conditions with Gene Ontology terms. ...
MUTATIONS
MUTATIONS

... • Immunity to HIV ...
Leukaemia Section t(6;14)(p25;q32) IRF4/IGH / t(2;6)(p12;p25) IRF4/IGK / t(6;22)(p25;q11) IRF4/IGL
Leukaemia Section t(6;14)(p25;q32) IRF4/IGH / t(2;6)(p12;p25) IRF4/IGK / t(6;22)(p25;q11) IRF4/IGL

... immunoglobulin heavy chain gene to the IRF4 gene have been shown to activate the transcription factor MUM1/IRF4 in multiple myeloma and in a subtype of mature B-cell lymphomas (Iida et al., 1997; Salaverria et al., 2011). The translocation leads to the overexpression of the MUM1/IRF4 gene. In multip ...
Unit 3 Problem Set Unit3_ProblemSet
Unit 3 Problem Set Unit3_ProblemSet

... 1. If a particular gene has a sequence that is 21% A (among A, C, G, and T), what percent can be deduced to be made up of G? 2. DNA has many properties that allowed us to isolate it in lab. For each property listed, describe how we exploited that property in the DNA isolation. a) VERY long b) Negati ...
Gene Frequencies Lab
Gene Frequencies Lab

... dominant to the absence of fur (f), which is recessive. Bengal tigers that inherit two dominant alleles (FF) or one dominant and one recessive allele (Ff) have fur, while tigers that inherit two recessive alleles (ff) have no fur. Because of this, the homozygous recessive trait is lethal. In this ac ...
EXTENSION OF MENDELIAN INHERITANCE: BEYOND
EXTENSION OF MENDELIAN INHERITANCE: BEYOND

... Mitochondria are organelles which function to produce energy as a result of cellular respiration of human, plants, …. Chloroplasts are organelles which function to produce sugars via photosynthesis in plants and algae. The genes located in mitochondria and chloroplasts are very important for proper ...
How does probability relate to genetics?
How does probability relate to genetics?

... What  is  the  chance  that  Bernard  will  have  pea  plant  offspring  that  match  the  phenotype  he  is  looking  for  (green,   ...
Chemistry Problem Solving Drill
Chemistry Problem Solving Drill

... (A) X-linked dominant (B) Autosomal dominant (C) Mitochondrial inheritance (D) X-linked recessive (E) Autosomal recessive A. Incorrect! In X-linked dominant inheritance transmission is through both parents: if the father is affected, then all female offspring are diseased, and if the mother is affec ...
Ch. 11 Genetic Problems
Ch. 11 Genetic Problems

... 4. In rabbits, the homozygous CC is normal, Cc results in rabbits with deformed legs, and cc is lethal. For a gene for coat color, the genotype BB produced black, Bb brown, and bb a white coat. If a deformed-leg, brown rabbit mates with a deformed-leg, white rabbit, determine the probability of gett ...
Gene Section FAD (Fanconi anaemia group D) Atlas of Genetics and Cytogenetics
Gene Section FAD (Fanconi anaemia group D) Atlas of Genetics and Cytogenetics

... This work is licensed under a Creative Commons Attribution-Non-commercial-No Derivative Works 2.0 France Licence. © 1998 Atlas of Genetics and Cytogenetics in Oncology and Haematology ...
Leukaemia Section -Y, Y loss in leukemia Atlas of Genetics and Cytogenetics
Leukaemia Section -Y, Y loss in leukemia Atlas of Genetics and Cytogenetics

... Loss of the Y chromosome from individual metaphases is common in metaphase cells from both PHAstimulated lymphocytes and spontaneously dividing bone marrow cells. The frequency of Y loss is greater in older men, and the size of the 45,X,-Y cell population probably increases gradually with advancing ...
Genetic Gamble
Genetic Gamble

... The phenotype of the full siblings provides a better reflection of the genes carried by the breeding individual than the phenotype of the parents. It is expected that the phenotypically normal dog with only one dysplastic littermate would carry fewer genes for dysplasia than the phenotypically norma ...
Appendix A: Re-Turking Results
Appendix A: Re-Turking Results

... combining automated extraction and crowdsourcing. Database (2014) Vol. 2014: article ID bau094; doi:10.1093/database/bau094 We also include the five items used for the qualifier. Turkers were required to answer at least four of these items correctly in order to participate in the task. We show the e ...
Seven types of pleiotropy
Seven types of pleiotropy

... a distinctive phenotype is far from obvious, and the possibility of ...
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tree - Tecfa

... Input data must be homolog! Number of character states Content of phylogenetic information Size of the dataset ...
Pet Points_ Pets` eye problems require expert care
Pet Points_ Pets` eye problems require expert care

... To surgically remove a cataract, the eye specialist uses a device called a phacoemulsification unit. This unit is often the same equipment used by medical doctors to perform cataract surgery in humans. The unit uses ultrasound to break up the cataract and then aspirates the remaining cataract fragme ...
A few inborn errors
A few inborn errors

...  Median actuarial survival was 49yrs; death from RCCs  Type I do not develop pheochromocytoma  Type II do have pheochromocytoma, +/- RCCs ...
Localization of CSNBX (CSNB4) between the retinitis
Localization of CSNBX (CSNB4) between the retinitis

... __ —i ...
Lab 08-Bacterial Transformation
Lab 08-Bacterial Transformation

... for the uptake of DNA from the external environment. E. coli does not appear to have these types of membrane proteins; however, placing E. coli in a relatively high concentration of calcium ions and performing a procedure called “heat shock” will stimulate these cells to take up pieces of foreign DN ...
Lack of correlation between IL-10R1 S138G loss-of
Lack of correlation between IL-10R1 S138G loss-of

... the different subunits that form the IL10 receptor. These proteins are encoded by the IL10RA and IL10RB genes, respectively. Three different homozygous mutations that perturb STAT3 (signal transducer and activator of transcription 3) phosphorylation via abrogated IL-10-induced immunomodulatory signa ...
AP Biology - Genetic Practice Problems Choose the answer which
AP Biology - Genetic Practice Problems Choose the answer which

... that were heterozygous at both loci (5.) none of the above 32. Huntington's disease is an example of a genetic disorder caused by (1.) late-acting lethal dominant allele (2.) a nonlethal dominant allele (3.) a late-acting recessive allele (4.) homozygous recessive alleles (5.) multiple alleles 33. S ...
review - acpsd.net
review - acpsd.net

... In which kind of cross would you expect to find two different kinds of ratios among the offspring, either 1:1 or 1:1:1:1? ...
Document
Document

... man with type A blood and a normal woman with type B blood already have one child with the disease. The woman is now pregnant for the second time. What is the probability that the second child will also have this disease? Assume both parents are heterozygous for the disease gene. 10. A man has six f ...
CONGENITAL DISORDERS OF GLYCOSYLATION
CONGENITAL DISORDERS OF GLYCOSYLATION

... glycoproteins, are linked to sugar chains, which increase their stability, determine its final shape, facilitate their interaction with other proteins, and also the differentiation and development of cells. These sugar chains are called glycans. Many of them have similar composition and are synthesi ...
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Neuronal ceroid lipofuscinosis

Neuronal ceroid lipofuscinoses (NCL) is the general name for a family of at least eight genetically separate neurodegenerative disorders that result from excessive accumulation of lipopigments (lipofuscin) in the body's tissues. These lipopigments are made up of fats and proteins. Their name comes from the word stem lipo-, which is a variation on ""lipid"" or ""fat"", and from the term pigment, used because the substances take on a greenish-yellow color when viewed under an ultraviolet light microscope. These lipofuscin materials build up in neuronal cells and many organs, including the liver, spleen, myocardium, and kidneys.
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