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RNA Splicing
RNA Splicing

Preparing and Analyzing Expressed Sequence Tags (ESTs) Library
Preparing and Analyzing Expressed Sequence Tags (ESTs) Library

... were determined. Also the 1001 ESTs (82.3%) showed significant similarities to putative genes with score of below 80% homology and 63 ESTs had no similarity to situated sequences in databases. Among the 1196 postnatal ESTs, 268 of them (22.4%) showed 80% and higher similarity; 923 ESTs (77.2%) showe ...
Characterization of the Arabidopsis thaliana Mutant pcb2 which
Characterization of the Arabidopsis thaliana Mutant pcb2 which

... in higher plants (Lange and Ghassemian 2003). Two glutamates form a porphobilinogen after the conversion to 5-aminolevulinic acids, and then four porphobilinogens make up a tetrapyrol ring that leads to protoporphyrin IX after some modifications. Insertion of a Mg ion into protoporphyrin IX by Mg-ch ...
Discovering the Distribution of Palindromic Sequences in the
Discovering the Distribution of Palindromic Sequences in the

... (length) (Supplementary Data Index 3) reads and writes .fasta files which are necessary file types for genetic sequences. Parameters were set on lengths of palindromes because 2 base pair (bp) palindromes are not important and a single nucleotide would not be a DNA palindrome. Due to the lack of lar ...
CoevolPaper2 - University of Illinois Archives
CoevolPaper2 - University of Illinois Archives

... time the various Darwinian transitions (to the vertical, or genealogical, mode of evolution) occurred in the three primary organismal lineages. The universally distributed r-proteins exhibit what is called the full canonical pattern [Woese et al., 2000], wherein the various taxa group into three dis ...
(De)regulation of key enzyme steps in the shikimate pathway and
(De)regulation of key enzyme steps in the shikimate pathway and

... Prephenate dehydratase (PDT), chorismate mutase (CM) and 3-deoxy-D-arabino-7-heptulosonate 7-phosphate (DAHP) synthase are key regulatory enzymes in aromatic amino acid biosynthesis in the actinomycete Amycolatopsis methanolica. Deregulated, feedback-control-resistant mutants were isolated by incuba ...
Geminivirus Replication Origins Have a Modular
Geminivirus Replication Origins Have a Modular

... TGMV A (Figure 1, cf. lanes 2 and 3), while BGMV B only replicated in the presence of BGMV A (cf. lanes 6 and 7). These results established that BGMV is able to replicate efficiently in tobacco cells and that, similar to TGMV A (Rogers et al., 1986; Hayes and Buck, 1989), BGMV A provides all of the ...


... same as those used for Williams and Williams 82. The majority of the amplified fragments were identical between these two pairs of NILs. All six primers except the primer UBC123 that produced polymorphic fragments in resistant cv. Williams 82 also generated the same fragments in resistant E420 but n ...
Phosphorus Partitioning of Soybean Lines Containing Different
Phosphorus Partitioning of Soybean Lines Containing Different

... appear to have a lower overall effect (Maupin and Rainey, 2011), which can at least partially be ameliorated by appropriate genetic selection (Anderson and Fehr, 2008; Spear and Fehr, 2007). Commercial cultivars with the reduced phytic acid trait derived from mutant alleles of the two Lpa genes are ...
マニュアル Megaprime DNA Labelling System
マニュアル Megaprime DNA Labelling System

... Previous protocols for the random primer labelling of DNA have required reaction times of at least 30 minutes. GE Healthcare’s Magaprime DNA labelling system allows the labelling of template DNA to the same high specific activity but at a greatly accelerated rate. Probes of specific activity 1.9x109 ...
Preview Sample 2
Preview Sample 2

... No, you cannot tell how coat color is inherited from the results of this one mating. In effect, this was a test cross – a cross between animals of different phenotypes resulting in offspring of two phenotypes. This does not indicate whether red or black is the dominant phenotype. To determine which ...
Chapter 10
Chapter 10

... makes up its genotype. ...
1 Single molecule sequencing of THCA synthase reveals
1 Single molecule sequencing of THCA synthase reveals

... has  5  THCAS  copies  in  total  (one  with  a  stop  codon,  one  that  is  inactive  and  three  that   are  putatively  active).  One  haplogroup  in  Chemdog91  is  identical  in  amino  acid   sequence  to  the  active  THCAS ...
AUTISM AS A PARADIGMATIC COMPLEX GENETIC DISORDER
AUTISM AS A PARADIGMATIC COMPLEX GENETIC DISORDER

... autism may more appropriately refer to autism spectrum disorder (ASD). Evidence suggests that ASD has a large genetic component with complex inheritance. The most recent estimate places the prevalence at 0.1% to 0.2% (24) for narrow diagnosis of autistic disorder and 0.6% for ASD. The prevalence of ...
Leukaemia Section t(7;12)(q34;p13), t(12;14)(p13;q11) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(7;12)(q34;p13), t(12;14)(p13;q11) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... interphasic nuclei from a patient with t(7;12)(q34;p13) using CCND2 flanking probes at 12p13. The centromeric BAC clone RP11-388F6 (red) and the telomeric BAC clone RP11-320N7 (green) show one fusion signal at the normal chromosome 12, and dissociated signals at der(12) (red signal) and der(7) ...
Chapter 6
Chapter 6

... Nübler-Jung 1994). It was originally based on anatomical observations (Geoffroy St. Hilaire 1822) and has recently received support from molecular data (De Robertis and Sasai 1996; Arendt and Nübler-Jung 1997). The theory predicts that the protostome and deuterostome nervous systems are homologous ( ...
Stage- and Tissue-Specific Expression of Ethylene Receptor
Stage- and Tissue-Specific Expression of Ethylene Receptor

... (Zhou et al., 1996; corresponding to LeETR1) is not affected by ethylene treatment. RP-ERS1 is under environmental control, and the mRNA level increases after submergence at low O2 concentrations and at high CO2 concentrations (Voesenek et al., 1997; Vriezen et al., 1997). However, because there are ...
A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal system. PLoS Genetics 7: e1002087.
A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal system. PLoS Genetics 7: e1002087.

... Many of the new tracheal genes are ‘‘morphogenesis genes’’ that encode proteins involved in cell structure or intracellular transport. The results suggest that genetic screens can elucidate a full organogenesis program and that over 200 patterning and morphogenesis genes are required to build even a ...
Chapter 8 Power Point
Chapter 8 Power Point

... • Nature - the influence of our inherited characteristics on our personality, physical growth, intellectual growth, and social interactions. • Nurture - the influence of the environment on personality, physical growth, intellectual growth, and social interactions. • Behavioral genetics – examines th ...
Trade-offs between tRNA abundance and mRNA secondary
Trade-offs between tRNA abundance and mRNA secondary

... choice and mRNA secondary structure affected translation, we used absolute expression data from a library of 29 DNA polymerase synonymous codon variants (36). In total, this contained 39 gene variants of which 30 exhibited measurable expression. Hence, only these 30 variants were included in our an ...
Close - Journal of Integrated OMICS
Close - Journal of Integrated OMICS

... Enterococci were obtained from 96 (98%) of the 98 samples analysed. E. hirae was the most prevalent detected species (35 isolates), followed by E. faecalis (30 isolates), E. faecium (27 isolates) and E. durans (4 isolates). E. coli isolates were detected in 90 (92%) of the 98 Iberian lynx faecal sam ...
Defining the Epigenetic Mechanism of Asymmetric Cell Division of
Defining the Epigenetic Mechanism of Asymmetric Cell Division of

... chromatids such that one specific member of the two is imprinted. The cell inheriting the template (arbitrarily named) Watson strand-containing chromatid is switching competent, and its sister cell, inheriting the template Crick strand-containing chromatid, is always incompetent (Klar 1987a, 1990, 20 ...
Genetic Characterization and Inheritance of Belly Spot
Genetic Characterization and Inheritance of Belly Spot

... In the cell wall of the melanocyte several proteins are attached, among them Kit, a transmembrane tyrosine kinase receptor. Kit has a ligand called Kitligand, steel or stem cell growth factor (SCF) (Alberts B. et al, 2002). From previous studies we know that Kit is involved in fetal development. The ...
Association of Apolipoprotein E Alleles with Susceptibility to Age
Association of Apolipoprotein E Alleles with Susceptibility to Age

... receptor-binding region, they affect the receptorbinding affinity of this molecule (25). It is known that the ε2 has a Cys at positions 112 and 158, which decrease the receptor-binding affinity of this molecule to its lowest. Therefore, the lipids, which are released through the age-related physiolo ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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