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5. Differential Gene Expression
5. Differential Gene Expression

... Location in DNA ­ highly variable:  ­ upstream (5’), downstream (3’), or within transcribed region  ­ in close proximity to gene or as many as 10 6  bp away  Enhancers and promoters are both DNA regulatory sequences,  but enhancers:  1) need a promoter to work  2) can work at a distance  3) can work ...
Heredity - Hazlet.org
Heredity - Hazlet.org

... Before Mendel performed his experiments people thought that offspring were just a mixture between the mother & father’s traits. For example if you mixed a short plant & a tall plant the offspring would be of medium height. Mendel noticed that each plant has two “heritable factors”. ...
Fulltext PDF - Indian Academy of Sciences
Fulltext PDF - Indian Academy of Sciences

... The impact of the operon model was great, and its main characteristics are still a part of our “common biological knowledge”: the expression of genes varies constantly, and is under the direct control of proteins – two ideas revolutionary at the time they were proposed. The paradox raised by Thomas ...
Lab 8
Lab 8

... Most cells in our body contain DNA, the molecule that makes up the genes that control our physical characteristics. Half your DNA came from your mother, and half from your father. Your DNA is what determines your eye color, hair color, height, blood type, and all other physical properties of your bo ...
Worksheet for Morgan/Carter Laboratory #9 Drosophila
Worksheet for Morgan/Carter Laboratory #9 Drosophila

... Correctly write the names of the wild-type and mutant alleles. By convention, wild-type alleles are designated with a superscript + after the name (e.g., gene+). ...
DNA, RNA and Protein Synthesis
DNA, RNA and Protein Synthesis

... ii. tRNA carrying the appropriate amino acid pairs its anticodon with the second codon in the mRNA iii. the ribosome then detaches methionine from the first tRNA, and a peptide bond forms between methionine and the second amino acid. iv. The first tRNA then exits the ribosome. The ribosome then move ...
DETERMINATIVE DEGREE AND NUCLEOTIDE CONTENT OF DNA
DETERMINATIVE DEGREE AND NUCLEOTIDE CONTENT OF DNA

... amino acids. For latter the analogous, but passive characteristics “predeterminativity” is also proposed, and it is shown that it correlates with the interaction energy of nitrous bases in corresponding DNA triplets. Purine-pyrimidine content of DNA sequences is considered in terms of the determinat ...
CH24
CH24

... --There are three primary sources of genetic variation Mutations are changes in the DNA structure Gene flow in genes’ movement [Sex determination (non somatic cells)] --It provides the raw material for natural selection ...
ATP16 Genes and Neighboring ORFs Are Duplicated on
ATP16 Genes and Neighboring ORFs Are Duplicated on

... al., 2003). The total DNAs (genomic DNAs) of the ATP16-disruptants derived from four different laboratory strains, DC5, LL20, W303-1A, and W303-1B, were digested with HincII, transferred on membranes, and then hybridized successively with DIG-labeled (a) ATP16 and (b) yeast HIS3 as probes. The DNAs ...
Review Materials for Chapter 14-16
Review Materials for Chapter 14-16

... Tobacco mosaic virus has RNA rather than DNA as its genetic material. In a hypothetical situation where RNA from a tobacco mosaic virus is mixed with proteins from a related DNA virus, the result could be a hybrid virus. If that virus were to infect a cell and reproduce, what would the resulting "of ...
Genetic Variation in Human Populations
Genetic Variation in Human Populations

chapter 18 microbial models: the genetics of viruses and bacteria
chapter 18 microbial models: the genetics of viruses and bacteria

...  Chemical modifications to the bacteria’s own DNA prevent its destruction by restriction nucleases.  Natural selection also favors phage mutants that are resistant to restriction enzymes.  In the lysogenic cycle, the phage genome replicates without destroying the host cell.  Temperate phages, li ...
Cynthia Smith
Cynthia Smith

... • practical for curation • cross-reference to other ontologies ...
Homologous Recombination (Introductory Concepts
Homologous Recombination (Introductory Concepts

... organism.  Bacteria  are  in  general  haploid,  containing  one  copy  of  the  chromosome  (for  practical  ...
Cis-regulatory mutations in human disease
Cis-regulatory mutations in human disease

... level of a given gene. Several studies have recently expanded on this concept by showing that variation in gene expression is widespread in the human genome [16]. Humans are more polymorphic at functional regulatory sequences than they are in coding exons [17]. Interestingly, variation in gene expre ...
name: student ID: Genetics L311 exam 3 November 21, 2014
name: student ID: Genetics L311 exam 3 November 21, 2014

... clone yourself might go awry (I’m not looking for reasons why your clone might be different from yourself but rather potential problems with the process itself (4 points). Many of the embryos won’t “take” (i.e. it’s extremely inefficient) Many of those that do develop have problems that can lead to ...
Notes For Genetics!! File
Notes For Genetics!! File

... saw chromosome behaviour during meiosis was like that of Mendel’s factors (fig 16.19 pg546) they made 3 key observations - chromosomes occur in pairs which segregate during meiosis - align independently of one another - inheritance of one doesn’t affect other chromosome being found in the gamete for ...
The Difference Makers
The Difference Makers

... 4. Would evolution still happen if there were no transposons, retrotransposons or retroviruses messing with the genome? [Yes, but it would probably be slower, relying on ordinary mutations that arise during DNA replication when cells divide or genetic recombination of chromosomes in a new generati ...
The Sequence Manipulation Suite—a collection of JavaScript prog
The Sequence Manipulation Suite—a collection of JavaScript prog

... Several minor enhancements have been made to the Sequence Manipulation Suite, including the addition of new features and options to many of the programs. For example, Filter DNA/Protein can now remove specific types of non-DNA and nonprotein characters, or it can replace them with alternative charac ...
protein - Warren County Schools
protein - Warren County Schools

... •A three-letter code is used because there are 20 different amino acids that are used to make proteins. •If a two-letter code were used there would not be enough codons to select all 20 amino acids. •That is, there are 4 bases in RNA, so 42 (4x 4)=16; where as 43 (4x4x4)=64. ...
7.2 Transcription and gene expression (HL ONLY
7.2 Transcription and gene expression (HL ONLY

... Transcription in Prokaryotes The RNA polymerase forms covalent bonds between the nucleotides. Free energy is released from the oxidation of the nucleoside triphosphates to form the bond. The bonds are formed by joining the 5' of the free nucleotide to the 3' end of the nucleotide already part of th ...
6.2 Genetic Engineering
6.2 Genetic Engineering

... Genetic Engineering Altering the sequence of DNA molecules Important in developing drugs ...
Genetic Testing
Genetic Testing

... This image was derived from Eukaryote DNA.svg, via Wikimedia Commons In the centre (nucleus) of most cells in your body, the DNA molecule is packaged into thread-like structures called chromosomes. You have 46 chromosomes arranged in 23 pairs. These include one pair of sex chromosomes (either XX for ...
Lecture 23
Lecture 23

... Culture: refers to differences in behaviors between various subgroups within a species where these differences are due to social learning (cultural transmission) rather than genetic differences Two examples of cultural transmission in animals: a. dialects in bird song---different breeding population ...
News in DNA/RNA electrophoresis: Midori
News in DNA/RNA electrophoresis: Midori

... Midori Green DNA Stain is a nucleic acid stain which can be used as a safer alternative to the traditional Ethidium Bromide stain for detecting nucleic acid in agarose gels. It is as sensitive as ethidium bromide and can be used exactly the same way in agarose gel electrophoresis (Figure 1). ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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