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00Exem hard
00Exem hard

... distance (BD) is the number of breakpoints in g, which is clearly equal to the number of breakpoints in h. The exemplar breakpoint distance (EBD) between G and H is the minimum, over all choices of exemplar strings g and h, of the breakpoint distance between g and h. A reversal transforms a string · ...
Construction of consecutive deletions of the Escherichia
Construction of consecutive deletions of the Escherichia

... chromosomes are multireplicons, and thus each origin of replication is not necessarily essential. Apart from the origin of replication, other cis-acting chromosome regions in eukaryotic cells include telomeric sequences, which are necessary for chromosome maintenance and centromeric regions, which a ...
Sec"on 8 - Small World Initiative
Sec"on 8 - Small World Initiative

... •  The  large  and  small  subunit  associate  only  in  the  presence  of  mRNA   •  The  mRNA  passes  through  a  “tunnel”  created  by  the  mature  ribosome   •  This  tunnel  contains  the  ac$ve  A,  P,  and  E  sites  where ...
File
File

... chat syndrome is due to a partial deletion of the short are of chromosome number 5. ...
Brooker Chapter 6
Brooker Chapter 6

... A plaque is a clear area on an otherwise opaque bacterial lawn on the agar surface of a petri dish It is caused by the lysis of bacterial cells as a result of the growth & reproduction of phages ...
Letter to the Editor
Letter to the Editor

... How reasonable is it to suppose that a toxin and antitoxin may come into linkage disequilibrium? It does appear unlikely that two such genes should appear side by side. However, the very same invasion condition is necessary for other analogous selfish genetic elements, and the required linkage diseq ...
Structure and evolution of Apetala3, a sex
Structure and evolution of Apetala3, a sex

... perennial herb of the Caryophyllaceae family. The sex of individual plants is genetically determined by sex chromosomes that were first described independently by Blackburn [6] and Winge [7]. Females are homogametic with a pair of X chromosomes, while the males are heterogametic, XY [8]. The X and Y ...
Bio101 Development Guide.pages
Bio101 Development Guide.pages

... This function is the working function, it calls other functions to convert file to final DNA sequences. It runs with the following steps. 1. Add length information to the end of the original DNA sequence and make sure the sequence length as the multiple of 50. 2. Split the DNA sequence to units with ...
Nucleic Acids Research
Nucleic Acids Research

... synthesis (UDS) in the wild type range (see Table 1), indicating that the isolated mouse cDNA harbors a functional ERCC-1 gene. The complete nucleotide sequence of AcDME and predicted amino acid sequence are given in Figure 1. The mouse ERCC-1 cDNA appears to encode a protein of 298 amino acids and ...
Gene Expression in Prokaryotes
Gene Expression in Prokaryotes

... genes together so that they can be regulated together. This grouping is called an operon. The clustered genes are transcribed together from one promoter giving a polycistronic messenger. ...
vital genes that flank sex-lethal, an x-linked sex
vital genes that flank sex-lethal, an x-linked sex

... 6E1-7B1 subregion of interest, and to which side of Sxl these mapped. Complementation tests of 6E1-731 lethals were generally done in groups of four to eight new mutants on the same side of Sxl, each initially being tested against all others in the group. When a complementation group acquired severa ...
genetic variation in isoniazid metabolism genes
genetic variation in isoniazid metabolism genes

... generally includes the administration of isoniazid (INH), a drug known to cause hepatotoxicity as a potentially serious side effect. INH-induced hepatotoxicity derives from toxic metabolites produced during INH breakdown. Genetic polymorphisms in Nacetyltransferase 2 (NAT2), a core enzyme in INH met ...
15_detaillectout
15_detaillectout

... homologous chromosomes at metaphase I of meiosis, which leads to the independent assortment of alleles. ...
1 A CAPS marker, FER-G8, for detection of Ty3 and Ty3a alleles
1 A CAPS marker, FER-G8, for detection of Ty3 and Ty3a alleles

... begomovirus resistance genes. Zamir et al. (1994) used LA1969 as a source of Ty-1 gene in chromosome 6 (ca. 8 cM). LA1969 was also the source of resistance against Tomato yellow leaf curl virus (TYLCV) for new lines developed in Cuba (Piňón et al., 2005). Scott and his team (Agrama and Scott, 2006; ...
Localized hypermutation and associated gene losses in legume
Localized hypermutation and associated gene losses in legume

... Carlow, Ireland Point mutations result from errors made during DNA replication or repair, so they are usually expected to be homogeneous across all regions of a genome. However, we have found a region of chloroplast DNA in plants related to sweetpea (Lathyrus) whose local point mutation rate is at l ...
At the Forefront in PGD
At the Forefront in PGD

Lecture 2 Turunen 14.9. - MyCourses
Lecture 2 Turunen 14.9. - MyCourses

... Highly condensed, duplicated chromosome of dividing nucleus ...
BWS - Beckwith-Wiedemann Syndrome support
BWS - Beckwith-Wiedemann Syndrome support

... or in women. Sometimes gene expression must be restricted to different parts of the body e.g. the genes responsible for sight must only be expressed in your eyes. Gene activity is controlled by chemical switches. As we have discussed, you inherit two copies of each gene: one copy from your mother ( ...
Mendel and the Laws of Inheritance
Mendel and the Laws of Inheritance

... there must be 2 genes that separate when gametes form Since traits can disappear for a generation and return unchanged to the next, they must be separate and distinct ...
CONTROL OF THE ACTIVITY OF THE HUMAN MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTOR
CONTROL OF THE ACTIVITY OF THE HUMAN MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTOR

... (Morris and Hollenbeck, 1993; Lee and Hollenbeck, 1995; Morris and Hollenbeck, 1995; Overly et al, 1996; Tanaka et al, 1998; Hurd and Saxton, 1996). Changes in shape and size can also be the consequence of processes like fusion or fission. Such events have been elegantly studied by time-lapse photog ...
Identification of the Minus-Dominance Gene Ortholog in
Identification of the Minus-Dominance Gene Ortholog in

... RWP12 is located at the N terminus; the initial methionine is set at the seventh residue of the multiple alignment. Since it seemed likely that the RWP-RK domain should extend farther into the 59-region, the DNA sequence neighboring RWP12 was analyzed by GENSCAN (Burge and Karlin 1997) with the ‘‘or ...
Section 13.2 Summary – pages 341
Section 13.2 Summary – pages 341

... different forms of a trait. • Hybrids produced by crossing two purebred plants are often larger and stronger than their parents. ...
Mendel and the Laws of Inheritance Biology Dobson High School
Mendel and the Laws of Inheritance Biology Dobson High School

... there must be 2 genes that separate when gametes form Since traits can disappear for a generation and return unchanged to the next, they must be separate and distinct ...
The role of duplications in the evolution of genomes highlights the
The role of duplications in the evolution of genomes highlights the

... Evolution Biologique et Modélisation.: UMR6632 CNRS, Université AixMarseille 1, 3 place V. Hugo, 13331 Marseille, France Full list of author information is available at the end of the article ...
Higher Biology
Higher Biology

... Considering the complexity of DNA, it is amazing that mutations are so infrequent. However, when a mutation does occur, resulting in a change in phenotype, the resulting individual is called a mutant. In a real sense therefore we are all mutants! Tuesday, May 23, 2017 ...
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Gene



A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.
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