Genetics and Genomics of Core Short Tandem Repeat Loci
... - Triallelic patterns have been observed for many of the core STR loci and recorded on the NIST STRBase Web site can occur as an imbalance in amounts between the three alleles (type 1) or equal amounts of all three alleles (type 2) ...
... - Triallelic patterns have been observed for many of the core STR loci and recorded on the NIST STRBase Web site can occur as an imbalance in amounts between the three alleles (type 1) or equal amounts of all three alleles (type 2) ...
Genetic Regulatory Network Identification Using
... Abstract— We present a method for identification of gene regulatory network topology using a time series of gene expression data. The underlying assumption is that the regulatory effects of a set of regulators to a gene can be described by a multivariate function. The multivariate function is constr ...
... Abstract— We present a method for identification of gene regulatory network topology using a time series of gene expression data. The underlying assumption is that the regulatory effects of a set of regulators to a gene can be described by a multivariate function. The multivariate function is constr ...
I = -[1/3*log 2 (1/3)+ 1/3*log 2 (1/3)+ 1/3*log 2 (1/3)] + 4.32 = 2.73
... Mutiple alignment of 3 protein sequences: ...
... Mutiple alignment of 3 protein sequences: ...
Annotations
... used to query the Gene Ontology database to recover associated functional terms. Also the evidence code of each particular annotation is recovered. The evidence codes indicate how the functional assignment in the Gene Ontology database has been obtained. 2. GO terms are selected from this original p ...
... used to query the Gene Ontology database to recover associated functional terms. Also the evidence code of each particular annotation is recovered. The evidence codes indicate how the functional assignment in the Gene Ontology database has been obtained. 2. GO terms are selected from this original p ...
CalbiCyc, Metabolic Pathways at the Candida Genome Database
... Curation of pathways at CGD Two-part curation approach: Step 1. Triage – Literature searches, assemble citation list – Decide to keep or delete pathway – Kept 181, deleted 227, added 15 ...
... Curation of pathways at CGD Two-part curation approach: Step 1. Triage – Literature searches, assemble citation list – Decide to keep or delete pathway – Kept 181, deleted 227, added 15 ...
isolation and sequencing of a genomic dna encoding for ascorbat
... biosynthetic pathway of AA is rarely met in plant species, being put into evidence so far only in spinach and beans [9]. Figure1 presents the two biosynthetic pathways of AA discussed above. Several strategies of achieving higher accumulation of biosynthetic products in plants, by means of altering ...
... biosynthetic pathway of AA is rarely met in plant species, being put into evidence so far only in spinach and beans [9]. Figure1 presents the two biosynthetic pathways of AA discussed above. Several strategies of achieving higher accumulation of biosynthetic products in plants, by means of altering ...
Gene Section PHOX2B (paired-like homeobox 2b) Atlas of Genetics and Cytogenetics
... system developmental stages by E2a and Hand2 (Hashimoto et al., 2011). Finally, SOX10 (Nagashimada et al., 2012), as well as PHOX2A and HASH1 (reviewed by Brunet and Pattyn, 2002) have shown a degree of cross-regulation with respect to PHOX2B. Hoxb1 and Hoxb2 have also shown to form a trimer with Pb ...
... system developmental stages by E2a and Hand2 (Hashimoto et al., 2011). Finally, SOX10 (Nagashimada et al., 2012), as well as PHOX2A and HASH1 (reviewed by Brunet and Pattyn, 2002) have shown a degree of cross-regulation with respect to PHOX2B. Hoxb1 and Hoxb2 have also shown to form a trimer with Pb ...
RELATIONSHIPS BETWEEN HEMATOLOGICAL PARAMETERS AND GLOBIN TYPES IN GENTILE DI PUGLIA OVINE BREED
... The effect of genotypes at globin systems on hematological data was evaluated on 289 Gentile di Puglia animals. A significant effect was detected for β-globin locus on hematocrit (HCT) and mean corpuscolar volume (MCV), with decreasing HCT and MCV for decreasing number of βA alleles in the genotype. ...
... The effect of genotypes at globin systems on hematological data was evaluated on 289 Gentile di Puglia animals. A significant effect was detected for β-globin locus on hematocrit (HCT) and mean corpuscolar volume (MCV), with decreasing HCT and MCV for decreasing number of βA alleles in the genotype. ...
Distinguishing Among Evolutionary Models for the Maintenance of
... end joining (NHEJ; reviewed in Paques and Haber 1999). The difference in the 2 pathways is largely based on whether homologous sequences are used as a template during double-strand break repair, and this difference can also be used to infer the mechanism by which individual genes are duplicated (une ...
... end joining (NHEJ; reviewed in Paques and Haber 1999). The difference in the 2 pathways is largely based on whether homologous sequences are used as a template during double-strand break repair, and this difference can also be used to infer the mechanism by which individual genes are duplicated (une ...
Chapter 20 Biotechnology Multiple-Choice Questions
... B) A genomic library varies, dependent on the cell type used to make it, whereas the content of a cDNA library does not. C) A genomic library can be made using a restriction enzyme and DNA ligase only, whereas a cDNA library requires both of these as well as reverse transcriptase and DNA polymerase. ...
... B) A genomic library varies, dependent on the cell type used to make it, whereas the content of a cDNA library does not. C) A genomic library can be made using a restriction enzyme and DNA ligase only, whereas a cDNA library requires both of these as well as reverse transcriptase and DNA polymerase. ...
14.1 The lacI Gene Encodes a Diffusible Repressor
... lacI gene on the chromosome may be a lacI– allele that causes constitutive expression, while the lacI gene on the F' factor may be normal. Second, the genes on the F' factor and the genes on the bacterial chromosome are not physically adjacent to each other. As we now know, the expression of the lac ...
... lacI gene on the chromosome may be a lacI– allele that causes constitutive expression, while the lacI gene on the F' factor may be normal. Second, the genes on the F' factor and the genes on the bacterial chromosome are not physically adjacent to each other. As we now know, the expression of the lac ...
DNA-Based Technologies
... of each cell is deoxyribonucleic acid (DNA). DNA is made up of pairs of four nucleotides abbreviated as “A”, “C”, “G”, and “T” (Figure 1). The entire genetic makeup, or genome, of an organism is stored in one or more chromosomes located inside each cell. DNA has two important functions; first, it tr ...
... of each cell is deoxyribonucleic acid (DNA). DNA is made up of pairs of four nucleotides abbreviated as “A”, “C”, “G”, and “T” (Figure 1). The entire genetic makeup, or genome, of an organism is stored in one or more chromosomes located inside each cell. DNA has two important functions; first, it tr ...
Identification of helper T cell master regulator candidates using the
... expression. To quantify the number of highly variable probesets in each plot, we use a variance cutoff of 0.04. In time, over 800 probesets are highly variable, whereas the treatment conditions lead to only 70 to 100 highly variable probesets (Fig. 2b– d). This suggests that the activation of cells ...
... expression. To quantify the number of highly variable probesets in each plot, we use a variance cutoff of 0.04. In time, over 800 probesets are highly variable, whereas the treatment conditions lead to only 70 to 100 highly variable probesets (Fig. 2b– d). This suggests that the activation of cells ...
Study Guide Chapter 11
... 1. Describe Mendel’s principle of independent assortment of alleles in your own words. Use an example to illustrate your answer. ...
... 1. Describe Mendel’s principle of independent assortment of alleles in your own words. Use an example to illustrate your answer. ...
Screening for homozygosity by descent in families with autosomal
... the minimum number since the sample size was small and there may be more alleles which can be detected from an adequate sample size. An initial screen was conducted with DNA from parents and one affected offspring. There were 10 sets of genotypes (one set for each family) per marker. Seven markers d ...
... the minimum number since the sample size was small and there may be more alleles which can be detected from an adequate sample size. An initial screen was conducted with DNA from parents and one affected offspring. There were 10 sets of genotypes (one set for each family) per marker. Seven markers d ...
Summarizer PowerPoint - Butler Biology
... which may contain 1000’s of genes! ANEUPLOIDY: an abnormal number of chromosomes resulting from mistakes in meiois ...
... which may contain 1000’s of genes! ANEUPLOIDY: an abnormal number of chromosomes resulting from mistakes in meiois ...
Single-Gene Inheritance (Learning Objectives) • Review the
... phenotype, allele, autosomal dominant and recessive traits, and a monohybrid cross. Explain Mendel’s law of allele segregation. Learn what is meant by a test cross and when it is used. Explain Mendel’s law of independent assortment for the simultaneous inheritance or two characters. Understand and u ...
... phenotype, allele, autosomal dominant and recessive traits, and a monohybrid cross. Explain Mendel’s law of allele segregation. Learn what is meant by a test cross and when it is used. Explain Mendel’s law of independent assortment for the simultaneous inheritance or two characters. Understand and u ...
2013 Holiday Lectures on Science Medicine in the
... their data to the spreadsheet, and the whole class can see it build collectively. If the tally column is built as a formula, it will grow as the students enter their data. You could draw an analogy between the collaborative, online building of a data set accomplished by the students and the genome a ...
... their data to the spreadsheet, and the whole class can see it build collectively. If the tally column is built as a formula, it will grow as the students enter their data. You could draw an analogy between the collaborative, online building of a data set accomplished by the students and the genome a ...
A Separate Peace – Pre
... Before you read: Although Gene does not want to attend meetings of the “Super Suicide Society,” he attends the meetings, stating, “Otherwise, I would have lost face with Phineas, and that would have been unthinkable.” What does this tell us about Gene’s attitude towards Phineas? How important is ...
... Before you read: Although Gene does not want to attend meetings of the “Super Suicide Society,” he attends the meetings, stating, “Otherwise, I would have lost face with Phineas, and that would have been unthinkable.” What does this tell us about Gene’s attitude towards Phineas? How important is ...
General enquiries on this form should be made to
... The executive summary must not exceed 2 sides in total of A4 and should be understandable to the intelligent non-scientist. It should cover the main objectives, methods and findings of the research, together with any other significant events and options for new work. TILLING (Targetted Local Lesions ...
... The executive summary must not exceed 2 sides in total of A4 and should be understandable to the intelligent non-scientist. It should cover the main objectives, methods and findings of the research, together with any other significant events and options for new work. TILLING (Targetted Local Lesions ...
Chapter 17--6 slides per page
... The information content of genes is in the specific sequences of nucleotides The DNA inherited by an organism leads to specific traits by dictating the synthesis of proteins Thus, proteins are the links between genotype and phenotype Gene expression, the process by which DNA directs protein ...
... The information content of genes is in the specific sequences of nucleotides The DNA inherited by an organism leads to specific traits by dictating the synthesis of proteins Thus, proteins are the links between genotype and phenotype Gene expression, the process by which DNA directs protein ...
Inked
... IV. Phylogenetic Trees A. Basically two ways to create a phylogenic tree: 1. using: 2. using: B. The molecular-based system 1. Phylogenetic Tree shown in Fig 1.6 a)) b) The tree is derived from c) Pioneered by ________________________(Box 17.4) 2. This organization suggests that most of the diversit ...
... IV. Phylogenetic Trees A. Basically two ways to create a phylogenic tree: 1. using: 2. using: B. The molecular-based system 1. Phylogenetic Tree shown in Fig 1.6 a)) b) The tree is derived from c) Pioneered by ________________________(Box 17.4) 2. This organization suggests that most of the diversit ...
Gene
A gene is a locus (or region) of DNA that encodes a functional RNA or protein product, and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as the gene–environment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life.Genes can acquire mutations in their sequence, leading to different variants, known as alleles, in the population. These alleles encode slightly different versions of a protein, which cause different phenotype traits. Colloquial usage of the term ""having a gene"" (e.g., ""good genes,"" ""hair colour gene"") typically refers to having a different allele of the gene. Genes evolve due to natural selection or survival of the fittest of the alleles.The concept of a gene continues to be refined as new phenomena are discovered. For example, regulatory regions of a gene can be far removed from its coding regions, and coding regions can be split into several exons. Some viruses store their genome in RNA instead of DNA and some gene products are functional non-coding RNAs. Therefore, a broad, modern working definition of a gene is any discrete locus of heritable, genomic sequence which affect an organism's traits by being expressed as a functional product or by regulation of gene expression.